IL142760A - Method for producing 4-Ä(2',5'-diamino-6'- halopyrimidine-4' -yl) aminoÜ-cyclopent -2- enyl-methanols - Google Patents

Method for producing 4-Ä(2',5'-diamino-6'- halopyrimidine-4' -yl) aminoÜ-cyclopent -2- enyl-methanols

Info

Publication number
IL142760A
IL142760A IL14276099A IL14276099A IL142760A IL 142760 A IL142760 A IL 142760A IL 14276099 A IL14276099 A IL 14276099A IL 14276099 A IL14276099 A IL 14276099A IL 142760 A IL142760 A IL 142760A
Authority
IL
Israel
Prior art keywords
diamino
cyclopent
amino
general formula
halopyrimidine
Prior art date
Application number
IL14276099A
Other languages
English (en)
Other versions
IL142760A0 (en
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of IL142760A0 publication Critical patent/IL142760A0/xx
Publication of IL142760A publication Critical patent/IL142760A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/50—Three nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IL14276099A 1998-10-30 1999-10-29 Method for producing 4-Ä(2',5'-diamino-6'- halopyrimidine-4' -yl) aminoÜ-cyclopent -2- enyl-methanols IL142760A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98120529 1998-10-30
US14610599P 1999-07-29 1999-07-29
PCT/EP1999/008270 WO2000026193A1 (de) 1998-10-30 1999-10-29 Verfahren zur herstellung von 4-[(2',5'-diamino-6'-halogenpyrimidin-4'-yl)amino]-cyclopent-2-enylmethanolen

Publications (2)

Publication Number Publication Date
IL142760A0 IL142760A0 (en) 2002-03-10
IL142760A true IL142760A (en) 2005-12-18

Family

ID=56289961

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14276099A IL142760A (en) 1998-10-30 1999-10-29 Method for producing 4-Ä(2',5'-diamino-6'- halopyrimidine-4' -yl) aminoÜ-cyclopent -2- enyl-methanols

Country Status (14)

Country Link
EP (1) EP1124805B1 (cs)
JP (1) JP4457496B2 (cs)
CN (1) CN1115338C (cs)
AT (1) ATE240945T1 (cs)
AU (1) AU1158000A (cs)
CA (1) CA2348374C (cs)
CZ (1) CZ300155B6 (cs)
DK (1) DK1124805T3 (cs)
ES (1) ES2200594T3 (cs)
HU (1) HU227559B1 (cs)
IL (1) IL142760A (cs)
PL (1) PL198180B1 (cs)
SK (1) SK285271B6 (cs)
WO (1) WO2000026193A1 (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6433170B1 (en) 1998-10-30 2002-08-13 Lonza Group Method for producing 4-[2',5'-diamino-6'-halopyrimidine-4'-yl)amino]- cyclopent-2-enylmethanols
WO2008084261A1 (en) 2007-01-10 2008-07-17 Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
WO2009087381A1 (en) 2008-01-08 2009-07-16 Merck Sharp & Dohme Ltd Pharmaceutically acceptable salts of 2-{4-[(3s)-piperidin-3- yl]phenyl} -2h-indazole-7-carboxamide
CN103626745B (zh) * 2013-12-04 2016-02-24 青岛黄海制药有限责任公司 一种替卡格雷中间体的制备方法
EP3860988A1 (en) 2018-10-03 2021-08-11 Tesaro, Inc. Crystalline forms of niraparib freebase

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3901502C2 (de) * 1988-01-20 2002-06-13 Univ Minnesota Didesoxydehydrocarbocyclische Nucleoside, diese enthaltende pharmazeutische Formulierungen und Pyrimidinylamino-cyclopentenylcarbinol-Derivate
GB8916698D0 (en) * 1989-07-21 1989-09-06 Beecham Group Plc Novel process
MY104575A (en) * 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.
CA2145928C (en) * 1994-04-27 2007-10-09 Gerhard Stucky N-(2-amino-4,6-dichloropyrimidin-5-yl)formamide, and a process for its preparation
HU226141B1 (en) * 1996-05-30 2008-05-28 Lonza Ag Process for the preparation of amino alcohols and derivatives thereof

Also Published As

Publication number Publication date
ATE240945T1 (de) 2003-06-15
HU227559B1 (en) 2011-08-29
CZ20011486A3 (cs) 2001-10-17
CA2348374C (en) 2009-04-07
PL198180B1 (pl) 2008-06-30
DK1124805T3 (da) 2003-09-15
CN1325386A (zh) 2001-12-05
IL142760A0 (en) 2002-03-10
CN1115338C (zh) 2003-07-23
PL347503A1 (en) 2002-04-08
JP2003500333A (ja) 2003-01-07
HUP0104045A2 (hu) 2002-05-29
EP1124805A1 (de) 2001-08-22
CA2348374A1 (en) 2000-05-11
CZ300155B6 (cs) 2009-02-25
AU1158000A (en) 2000-05-22
SK285271B6 (sk) 2006-10-05
WO2000026193A1 (de) 2000-05-11
SK5692001A3 (en) 2001-12-03
EP1124805B1 (de) 2003-05-21
JP4457496B2 (ja) 2010-04-28
HUP0104045A3 (en) 2002-07-29
ES2200594T3 (es) 2004-03-01

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Legal Events

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KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees