DE59905679D1 - Verfahren zur herstellung von 4-[(2',5'-diamino-6'-halogenpyrimidin-4'-yl)amino]-cyclopent-2-enylmethanolen - Google Patents

Verfahren zur herstellung von 4-[(2',5'-diamino-6'-halogenpyrimidin-4'-yl)amino]-cyclopent-2-enylmethanolen

Info

Publication number
DE59905679D1
DE59905679D1 DE59905679T DE59905679T DE59905679D1 DE 59905679 D1 DE59905679 D1 DE 59905679D1 DE 59905679 T DE59905679 T DE 59905679T DE 59905679 T DE59905679 T DE 59905679T DE 59905679 D1 DE59905679 D1 DE 59905679D1
Authority
DE
Germany
Prior art keywords
halogenpyrimidin
enylmethanols
cyclopent
diamino
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE59905679T
Other languages
English (en)
Inventor
Walter Brieden
Elie Saikali
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lonza AG
Original Assignee
Lonza AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza AG filed Critical Lonza AG
Priority claimed from PCT/EP1999/008270 external-priority patent/WO2000026193A1/de
Application granted granted Critical
Publication of DE59905679D1 publication Critical patent/DE59905679D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/50—Three nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
DE59905679T 1998-10-30 1999-10-29 Verfahren zur herstellung von 4-[(2',5'-diamino-6'-halogenpyrimidin-4'-yl)amino]-cyclopent-2-enylmethanolen Expired - Lifetime DE59905679D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98120529 1998-10-30
US14610599P 1999-07-29 1999-07-29
PCT/EP1999/008270 WO2000026193A1 (de) 1998-10-30 1999-10-29 Verfahren zur herstellung von 4-[(2',5'-diamino-6'-halogenpyrimidin-4'-yl)amino]-cyclopent-2-enylmethanolen

Publications (1)

Publication Number Publication Date
DE59905679D1 true DE59905679D1 (de) 2003-06-26

Family

ID=26149750

Family Applications (1)

Application Number Title Priority Date Filing Date
DE59905679T Expired - Lifetime DE59905679D1 (de) 1998-10-30 1999-10-29 Verfahren zur herstellung von 4-[(2',5'-diamino-6'-halogenpyrimidin-4'-yl)amino]-cyclopent-2-enylmethanolen

Country Status (5)

Country Link
US (1) US6433170B1 (de)
KR (1) KR100606625B1 (de)
DE (1) DE59905679D1 (de)
HK (1) HK1042474B (de)
NO (1) NO318051B1 (de)

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4916224A (en) 1988-01-20 1990-04-10 Regents Of The University Of Minnesota Dideoxycarbocyclic nucleosides
US4931559A (en) 1988-01-20 1990-06-05 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
US5175292A (en) 1988-01-20 1992-12-29 Regents Of The University Of Minnesota Intermediates for the preparation of dideoxycarbocyclic nucleosides
JP2793825B2 (ja) 1988-01-20 1998-09-03 リージヤンツ・オブ・ザ・ユニバーシテイ・オブ・ミネソタ ジデオキシジデヒドロ炭素環式ヌクレオシド
US4950758A (en) 1988-01-20 1990-08-21 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
US5567703A (en) 1988-01-20 1996-10-22 Regents Of The University Of Minnesota Method for treating HIV infections with dideoxycarbocyclic nucleosides
US5631370A (en) 1988-01-20 1997-05-20 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
GB8815265D0 (en) 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
GB8916698D0 (en) 1989-07-21 1989-09-06 Beecham Group Plc Novel process
MY104575A (en) 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.
CA2145928C (en) 1994-04-27 2007-10-09 Gerhard Stucky N-(2-amino-4,6-dichloropyrimidin-5-yl)formamide, and a process for its preparation
EP0904348B1 (de) 1996-05-30 2004-11-24 Lonza AG Verfahren zur herstellung von aminoalkoholen und derivaten davon
CA2348374C (en) 1998-10-30 2009-04-07 Lonza Ag Method for producing 4- [(2',5'- diamino-6'- halopyrimidine- 4'-yl)amino]- cyclopent- 2-enylmethanols

Also Published As

Publication number Publication date
HK1042474A1 (en) 2002-08-16
NO20012028D0 (no) 2001-04-25
NO20012028L (no) 2001-04-25
KR100606625B1 (ko) 2006-07-28
HK1042474B (zh) 2003-11-21
NO318051B1 (no) 2005-01-24
US6433170B1 (en) 2002-08-13
KR20010092426A (ko) 2001-10-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition