HK1042474B - 製備4-[(2'，5'-二胺基-6'-滷代咪啶-4'-)胺]-環戊-2-烯-甲醇的方法 - Google Patents

製備4-[(2'，5'-二胺基-6'-滷代咪啶-4'-)胺]-環戊-2-烯-甲醇的方法

Info

Publication number
HK1042474B
HK1042474B HK02101383.1A HK02101383A HK1042474B HK 1042474 B HK1042474 B HK 1042474B HK 02101383 A HK02101383 A HK 02101383A HK 1042474 B HK1042474 B HK 1042474B
Authority
HK
Hong Kong
Prior art keywords
enylmethanols
halopyrimidine
cyclopent
diamino
amino
Prior art date
Application number
HK02101383.1A
Other languages
English (en)
Other versions
HK1042474A1 (en
Inventor
Brieden Walter
Saikali Elie
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP1999/008270 external-priority patent/WO2000026193A1/de
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of HK1042474A1 publication Critical patent/HK1042474A1/xx
Publication of HK1042474B publication Critical patent/HK1042474B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/50—Three nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
HK02101383.1A 1998-10-30 2002-02-22 製備4-[(2'，5'-二胺基-6'-滷代咪啶-4'-)胺]-環戊-2-烯-甲醇的方法 HK1042474B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98120529 1998-10-30
US14610599P 1999-07-29 1999-07-29
PCT/EP1999/008270 WO2000026193A1 (de) 1998-10-30 1999-10-29 Verfahren zur herstellung von 4-[(2',5'-diamino-6'-halogenpyrimidin-4'-yl)amino]-cyclopent-2-enylmethanolen

Publications (2)

Publication Number Publication Date
HK1042474A1 HK1042474A1 (en) 2002-08-16
HK1042474B true HK1042474B (zh) 2003-11-21

Family

ID=26149750

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02101383.1A HK1042474B (zh) 1998-10-30 2002-02-22 製備4-[(2'，5'-二胺基-6'-滷代咪啶-4'-)胺]-環戊-2-烯-甲醇的方法

Country Status (5)

Country Link
US (1) US6433170B1 (zh)
KR (1) KR100606625B1 (zh)
DE (1) DE59905679D1 (zh)
HK (1) HK1042474B (zh)
NO (1) NO318051B1 (zh)

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO169123C (no) 1988-01-20 1992-05-13 Univ Minnesota Analogifremgangsmaate til fremstilling av terapeutisk aktive karbocykliske 2',3'-dideoksy-2',3'-didehydropurinnukleosidanaloger
US5567703A (en) 1988-01-20 1996-10-22 Regents Of The University Of Minnesota Method for treating HIV infections with dideoxycarbocyclic nucleosides
US5631370A (en) 1988-01-20 1997-05-20 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
US4916224A (en) 1988-01-20 1990-04-10 Regents Of The University Of Minnesota Dideoxycarbocyclic nucleosides
US4950758A (en) 1988-01-20 1990-08-21 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
US5175292A (en) 1988-01-20 1992-12-29 Regents Of The University Of Minnesota Intermediates for the preparation of dideoxycarbocyclic nucleosides
US4931559A (en) 1988-01-20 1990-06-05 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
GB8815265D0 (en) 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
GB8916698D0 (en) 1989-07-21 1989-09-06 Beecham Group Plc Novel process
MY104575A (en) 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.
CA2145928C (en) 1994-04-27 2007-10-09 Gerhard Stucky N-(2-amino-4,6-dichloropyrimidin-5-yl)formamide, and a process for its preparation
WO1997045529A1 (de) 1996-05-30 1997-12-04 Lonza Ag Verfahren zur herstellung von aminoalkoholen und derivaten davon
HU227559B1 (en) 1998-10-30 2011-08-29 Lonza Ag Method for producing 4-[(2',5'-diamino-6'-halopyrimidine-4'-yl)amino]-cyclopent-2-enylmethanols

Also Published As

Publication number Publication date
NO20012028L (no) 2001-04-25
KR100606625B1 (ko) 2006-07-28
NO318051B1 (no) 2005-01-24
KR20010092426A (ko) 2001-10-24
US6433170B1 (en) 2002-08-13
HK1042474A1 (en) 2002-08-16
DE59905679D1 (de) 2003-06-26
NO20012028D0 (no) 2001-04-25

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20131029