PL277261A1 - Method of obtaining analogues of dideoxydihydrocarbocyclic nucleosides - Google Patents

Method of obtaining analogues of dideoxydihydrocarbocyclic nucleosides

Info

Publication number
PL277261A1
PL277261A1 PL89277261A PL27726189A PL277261A1 PL 277261 A1 PL277261 A1 PL 277261A1 PL 89277261 A PL89277261 A PL 89277261A PL 27726189 A PL27726189 A PL 27726189A PL 277261 A1 PL277261 A1 PL 277261A1
Authority
PL
Poland
Prior art keywords
dideoxydihydrocarbocyclic
nucleosides
obtaining analogues
analogues
obtaining
Prior art date
Application number
PL89277261A
Other versions
PL163814B1 (en
Original Assignee
Univ Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/146,252 external-priority patent/US4916224A/en
Priority claimed from GB888821011A external-priority patent/GB8821011D0/en
Priority claimed from US07/278,652 external-priority patent/US4931559A/en
Application filed by Univ Minnesota filed Critical Univ Minnesota
Publication of PL277261A1 publication Critical patent/PL277261A1/en
Publication of PL163814B1 publication Critical patent/PL163814B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
PL89277261A 1988-01-20 1989-01-19 Method of obtaining novel analogous compounds of dideoxy-didehydrocarbocyclic nucleosides PL163814B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/146,252 US4916224A (en) 1988-01-20 1988-01-20 Dideoxycarbocyclic nucleosides
GB888821011A GB8821011D0 (en) 1988-09-07 1988-09-07 Chemical compounds
US07/278,652 US4931559A (en) 1988-01-20 1988-12-05 Optically-active isomers of dideoxycarbocyclic nucleosides

Publications (2)

Publication Number Publication Date
PL277261A1 true PL277261A1 (en) 1989-09-18
PL163814B1 PL163814B1 (en) 1994-05-31

Family

ID=27264063

Family Applications (1)

Application Number Title Priority Date Filing Date
PL89277261A PL163814B1 (en) 1988-01-20 1989-01-19 Method of obtaining novel analogous compounds of dideoxy-didehydrocarbocyclic nucleosides

Country Status (29)

Country Link
JP (1) JP2793825B2 (en)
KR (1) KR0127137B1 (en)
AT (1) AT397801B (en)
AU (2) AU626278B2 (en)
BE (1) BE1003815A4 (en)
CA (1) CA1339896C (en)
CH (1) CH679152A5 (en)
DE (1) DE3901502C2 (en)
DK (1) DK175131B1 (en)
ES (1) ES2010091A6 (en)
FI (1) FI93546C (en)
FR (1) FR2626002B1 (en)
GB (1) GB2217320B (en)
GR (1) GR890100033A (en)
HU (1) HU203755B (en)
IE (1) IE62275B1 (en)
IL (1) IL88999A (en)
IT (1) IT1229531B (en)
LU (1) LU87437A1 (en)
MY (1) MY103801A (en)
NL (1) NL8900122A (en)
NO (1) NO169123C (en)
NZ (1) NZ227663A (en)
OA (1) OA09031A (en)
PL (1) PL163814B1 (en)
PT (1) PT89482B (en)
RU (1) RU2114846C1 (en)
SE (1) SE505213C2 (en)
YU (1) YU47791B (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1215339B (en) * 1987-01-14 1990-02-08 Co Pharma Corp Srl PROCEDURE FOR THE PREPARATION OF 9- (HYDROXIALCHIL) -IPOXANTINE
US5631370A (en) 1988-01-20 1997-05-20 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
GB8815265D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
US4939252A (en) * 1989-04-20 1990-07-03 Hoffmann-La Roche Inc. Novel intermediates for the preparation of Carbovir
EP0479822B1 (en) * 1989-06-27 1999-08-18 The Wellcome Foundation Limited Therapeutic nucleosides
GB8916478D0 (en) * 1989-07-19 1989-09-06 Glaxo Group Ltd Chemical process
GB8916479D0 (en) * 1989-07-19 1989-09-06 Glaxo Group Ltd Chemical process
GB8916477D0 (en) * 1989-07-19 1989-09-06 Glaxo Group Ltd Chemical process
GB8916480D0 (en) * 1989-07-19 1989-09-06 Glaxo Group Ltd Chemical process
MY104575A (en) * 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.
US5144034A (en) * 1990-04-06 1992-09-01 Glaxo Inc. Process for the synthesis of cyclopentene derivatives of purines
US5057630A (en) * 1990-04-06 1991-10-15 Glaxo Inc. Synthesis of cyclopentene derivatives
US5241069A (en) * 1990-04-06 1993-08-31 Glaxo Inc. Carbonate intermediates for the synthesis of purine substituted cyclopentene derivatives
US5126452A (en) * 1990-04-06 1992-06-30 Glaxo Inc. Synthesis of purine substituted cyclopentene derivatives
GB9108376D0 (en) * 1991-04-19 1991-06-05 Enzymatix Ltd Cyclopentenes
CA2175897A1 (en) * 1993-11-12 1995-05-18 David R. Borcherding 6-oxo-nucleosides useful as immunosuppressants
GB9721780D0 (en) 1997-10-14 1997-12-10 Glaxo Group Ltd Process for the synthesis of chloropurine intermediates
CN1115338C (en) * 1998-10-30 2003-07-23 隆萨股份公司 Method for producing 4[(2',5'-diamino-6'-halopyrimidine-4'-yl) amino]-cyclopent-2-enylmethanols
US6433170B1 (en) 1998-10-30 2002-08-13 Lonza Group Method for producing 4-[2',5'-diamino-6'-halopyrimidine-4'-yl)amino]- cyclopent-2-enylmethanols
TWI229674B (en) 1998-12-04 2005-03-21 Astra Pharma Prod Novel triazolo[4,5-d]pyrimidine compounds, pharmaceutical composition containing the same, their process for preparation and uses
GB9903091D0 (en) * 1999-02-12 1999-03-31 Glaxo Group Ltd Therapeutic nucleoside compound
AR039540A1 (en) * 2002-05-13 2005-02-23 Tibotec Pharm Ltd MICROBICIDE COMPOUNDS WITH PIRIMIDINE OR TRIAZINE CONTENT
EP3831388B1 (en) 2018-07-27 2024-02-28 FUJIFILM Corporation Cyclopentenyl purine derivative or salt thereof for use in suppressing adenovirus
TW202019941A (en) 2018-07-27 2020-06-01 日商富士軟片股份有限公司 Cyclobutylpurine derivative or its salt
JP2023519882A (en) 2020-03-27 2023-05-15 ソム、イノベーション、バイオテック、ソシエダッド、アノニマ Compounds useful for treating synucleinopathies

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268672A (en) * 1977-02-09 1981-05-19 The Regents Of The University Of Minnesota Adenosine deaminase resistant antiviral purine nucleosides and method of preparation
US4742064A (en) * 1985-09-10 1988-05-03 Regents Of The University Of Minnesota Antiviral carbocyclic analogs of xylofuranosylpurines
JPS62177234A (en) * 1986-01-30 1987-08-04 Mitsubishi Heavy Ind Ltd Production device of carbon fiber by centrifugal spinning
IN164556B (en) * 1986-03-06 1989-04-08 Takeda Chemical Industries Ltd
NZ229453A (en) * 1988-06-10 1991-08-27 Univ Minnesota & Southern Rese A pharmaceutical composition containing purine derivatives with nucleosides such as azt, as antiviral agents
GB8815265D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
MY104575A (en) * 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.

Also Published As

Publication number Publication date
BE1003815A4 (en) 1992-06-23
DK23489D0 (en) 1989-01-19
FR2626002A1 (en) 1989-07-21
DK23489A (en) 1989-07-21
KR0127137B1 (en) 1997-12-29
DK175131B1 (en) 2004-06-14
FI890286L (en) 1989-07-21
NO890253D0 (en) 1989-01-19
ES2010091A6 (en) 1989-10-16
NO169123C (en) 1992-05-13
NL8900122A (en) 1989-08-16
IE62275B1 (en) 1995-01-25
CA1339896C (en) 1998-06-02
HU203755B (en) 1991-09-30
NO169123B (en) 1992-02-03
RU2114846C1 (en) 1998-07-10
OA09031A (en) 1991-03-31
CH679152A5 (en) 1991-12-31
ATA10689A (en) 1993-11-15
FI890286A0 (en) 1989-01-19
FI93546B (en) 1995-01-13
IE890153L (en) 1989-07-20
DE3901502A1 (en) 1989-07-27
AU637015B2 (en) 1993-05-13
GR890100033A (en) 1994-03-31
LU87437A1 (en) 1989-08-30
GB8901187D0 (en) 1989-03-15
MY103801A (en) 1993-09-30
GB2217320A (en) 1989-10-25
KR890011902A (en) 1989-08-23
AU1018092A (en) 1992-03-12
PL163814B1 (en) 1994-05-31
JPH02196788A (en) 1990-08-03
IT1229531B (en) 1991-09-04
AU2867189A (en) 1989-07-20
AT397801B (en) 1994-07-25
JP2793825B2 (en) 1998-09-03
SE8900192L (en) 1989-07-21
FR2626002B1 (en) 1994-01-28
DE3901502C2 (en) 2002-06-13
HUT48887A (en) 1989-07-28
GB2217320B (en) 1992-04-08
NZ227663A (en) 1990-09-26
SE8900192D0 (en) 1989-01-19
SE505213C2 (en) 1997-07-14
IT8947546A0 (en) 1989-01-19
AU626278B2 (en) 1992-07-30
NO890253L (en) 1989-07-21
YU47791B (en) 1996-01-09
IL88999A (en) 1994-12-29
PT89482A (en) 1989-10-04
YU12389A (en) 1991-10-31
PT89482B (en) 1994-02-28
FI93546C (en) 1995-04-25
IL88999A0 (en) 1989-08-15

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