FR2626002B1 - DIDEOXYDIDEHYDROCARBOCYCLIC NUCLEOSIDES AND PHARMACEUTICAL COMPOSITION CONTAINING THEM - Google Patents
DIDEOXYDIDEHYDROCARBOCYCLIC NUCLEOSIDES AND PHARMACEUTICAL COMPOSITION CONTAINING THEMInfo
- Publication number
- FR2626002B1 FR2626002B1 FR8900592A FR8900592A FR2626002B1 FR 2626002 B1 FR2626002 B1 FR 2626002B1 FR 8900592 A FR8900592 A FR 8900592A FR 8900592 A FR8900592 A FR 8900592A FR 2626002 B1 FR2626002 B1 FR 2626002B1
- Authority
- FR
- France
- Prior art keywords
- dideoxydidehydrocarbocyclic
- nucleosides
- pharmaceutical composition
- composition containing
- pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/146,252 US4916224A (en) | 1988-01-20 | 1988-01-20 | Dideoxycarbocyclic nucleosides |
GB888821011A GB8821011D0 (en) | 1988-09-07 | 1988-09-07 | Chemical compounds |
US07/278,652 US4931559A (en) | 1988-01-20 | 1988-12-05 | Optically-active isomers of dideoxycarbocyclic nucleosides |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2626002A1 FR2626002A1 (en) | 1989-07-21 |
FR2626002B1 true FR2626002B1 (en) | 1994-01-28 |
Family
ID=27264063
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8900592A Expired - Lifetime FR2626002B1 (en) | 1988-01-20 | 1989-01-19 | DIDEOXYDIDEHYDROCARBOCYCLIC NUCLEOSIDES AND PHARMACEUTICAL COMPOSITION CONTAINING THEM |
Country Status (29)
Country | Link |
---|---|
JP (1) | JP2793825B2 (en) |
KR (1) | KR0127137B1 (en) |
AT (1) | AT397801B (en) |
AU (2) | AU626278B2 (en) |
BE (1) | BE1003815A4 (en) |
CA (1) | CA1339896C (en) |
CH (1) | CH679152A5 (en) |
DE (1) | DE3901502C2 (en) |
DK (1) | DK175131B1 (en) |
ES (1) | ES2010091A6 (en) |
FI (1) | FI93546C (en) |
FR (1) | FR2626002B1 (en) |
GB (1) | GB2217320B (en) |
GR (1) | GR890100033A (en) |
HU (1) | HU203755B (en) |
IE (1) | IE62275B1 (en) |
IL (1) | IL88999A (en) |
IT (1) | IT1229531B (en) |
LU (1) | LU87437A1 (en) |
MY (1) | MY103801A (en) |
NL (1) | NL8900122A (en) |
NO (1) | NO169123C (en) |
NZ (1) | NZ227663A (en) |
OA (1) | OA09031A (en) |
PL (1) | PL163814B1 (en) |
PT (1) | PT89482B (en) |
RU (1) | RU2114846C1 (en) |
SE (1) | SE505213C2 (en) |
YU (1) | YU47791B (en) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1215339B (en) * | 1987-01-14 | 1990-02-08 | Co Pharma Corp Srl | PROCEDURE FOR THE PREPARATION OF 9- (HYDROXIALCHIL) -IPOXANTINE |
US5631370A (en) | 1988-01-20 | 1997-05-20 | Regents Of The University Of Minnesota | Optically-active isomers of dideoxycarbocyclic nucleosides |
GB8815265D0 (en) * | 1988-06-27 | 1988-08-03 | Wellcome Found | Therapeutic nucleosides |
US4939252A (en) * | 1989-04-20 | 1990-07-03 | Hoffmann-La Roche Inc. | Novel intermediates for the preparation of Carbovir |
DE69033252T2 (en) * | 1989-06-27 | 1999-12-09 | The Wellcome Foundation Ltd., Greenford | THERAPEUTIC NUCLEOSIDES |
GB8916477D0 (en) * | 1989-07-19 | 1989-09-06 | Glaxo Group Ltd | Chemical process |
GB8916479D0 (en) * | 1989-07-19 | 1989-09-06 | Glaxo Group Ltd | Chemical process |
GB8916478D0 (en) * | 1989-07-19 | 1989-09-06 | Glaxo Group Ltd | Chemical process |
GB8916480D0 (en) * | 1989-07-19 | 1989-09-06 | Glaxo Group Ltd | Chemical process |
MY104575A (en) * | 1989-12-22 | 1994-04-30 | The Wellcome Foundation Ltd | Therapeutic nucleosides. |
US5126452A (en) * | 1990-04-06 | 1992-06-30 | Glaxo Inc. | Synthesis of purine substituted cyclopentene derivatives |
US5241069A (en) * | 1990-04-06 | 1993-08-31 | Glaxo Inc. | Carbonate intermediates for the synthesis of purine substituted cyclopentene derivatives |
US5144034A (en) * | 1990-04-06 | 1992-09-01 | Glaxo Inc. | Process for the synthesis of cyclopentene derivatives of purines |
US5057630A (en) * | 1990-04-06 | 1991-10-15 | Glaxo Inc. | Synthesis of cyclopentene derivatives |
GB9108376D0 (en) * | 1991-04-19 | 1991-06-05 | Enzymatix Ltd | Cyclopentenes |
AU677732B2 (en) * | 1993-11-12 | 1997-05-01 | Merrell Pharmaceuticals Inc. | 6-oxo-nucleosides useful as immunosuppressants |
GB9721780D0 (en) * | 1997-10-14 | 1997-12-10 | Glaxo Group Ltd | Process for the synthesis of chloropurine intermediates |
HU227559B1 (en) * | 1998-10-30 | 2011-08-29 | Lonza Ag | Method for producing 4-[(2',5'-diamino-6'-halopyrimidine-4'-yl)amino]-cyclopent-2-enylmethanols |
US6433170B1 (en) | 1998-10-30 | 2002-08-13 | Lonza Group | Method for producing 4-[2',5'-diamino-6'-halopyrimidine-4'-yl)amino]- cyclopent-2-enylmethanols |
TWI229674B (en) | 1998-12-04 | 2005-03-21 | Astra Pharma Prod | Novel triazolo[4,5-d]pyrimidine compounds, pharmaceutical composition containing the same, their process for preparation and uses |
GB9903091D0 (en) * | 1999-02-12 | 1999-03-31 | Glaxo Group Ltd | Therapeutic nucleoside compound |
AR039540A1 (en) * | 2002-05-13 | 2005-02-23 | Tibotec Pharm Ltd | MICROBICIDE COMPOUNDS WITH PIRIMIDINE OR TRIAZINE CONTENT |
TW202019942A (en) | 2018-07-27 | 2020-06-01 | 日商富士軟片股份有限公司 | Cyclopentenyl purine derivative or salt thereof |
JP2023519882A (en) | 2020-03-27 | 2023-05-15 | ソム、イノベーション、バイオテック、ソシエダッド、アノニマ | Compounds useful for treating synucleinopathies |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4268672A (en) * | 1977-02-09 | 1981-05-19 | The Regents Of The University Of Minnesota | Adenosine deaminase resistant antiviral purine nucleosides and method of preparation |
US4742064A (en) * | 1985-09-10 | 1988-05-03 | Regents Of The University Of Minnesota | Antiviral carbocyclic analogs of xylofuranosylpurines |
JPS62177234A (en) * | 1986-01-30 | 1987-08-04 | Mitsubishi Heavy Ind Ltd | Production device of carbon fiber by centrifugal spinning |
IN164556B (en) * | 1986-03-06 | 1989-04-08 | Takeda Chemical Industries Ltd | |
NZ229453A (en) * | 1988-06-10 | 1991-08-27 | Univ Minnesota & Southern Rese | A pharmaceutical composition containing purine derivatives with nucleosides such as azt, as antiviral agents |
GB8815265D0 (en) * | 1988-06-27 | 1988-08-03 | Wellcome Found | Therapeutic nucleosides |
MY104575A (en) * | 1989-12-22 | 1994-04-30 | The Wellcome Foundation Ltd | Therapeutic nucleosides. |
-
1989
- 1989-01-19 NO NO890253A patent/NO169123C/en not_active IP Right Cessation
- 1989-01-19 IT IT8947546A patent/IT1229531B/en active
- 1989-01-19 DE DE3901502A patent/DE3901502C2/en not_active Expired - Lifetime
- 1989-01-19 GB GB8901187A patent/GB2217320B/en not_active Expired - Lifetime
- 1989-01-19 HU HU89210A patent/HU203755B/en unknown
- 1989-01-19 DK DK198900234A patent/DK175131B1/en not_active IP Right Cessation
- 1989-01-19 YU YU12389A patent/YU47791B/en unknown
- 1989-01-19 IL IL8899989A patent/IL88999A/en unknown
- 1989-01-19 SE SE8900192A patent/SE505213C2/en not_active IP Right Cessation
- 1989-01-19 FR FR8900592A patent/FR2626002B1/en not_active Expired - Lifetime
- 1989-01-19 RU RU92004364A patent/RU2114846C1/en active
- 1989-01-19 MY MYPI89000064A patent/MY103801A/en unknown
- 1989-01-19 FI FI890286A patent/FI93546C/en not_active IP Right Cessation
- 1989-01-19 JP JP1008744A patent/JP2793825B2/en not_active Expired - Lifetime
- 1989-01-19 GR GR890100033A patent/GR890100033A/en not_active IP Right Cessation
- 1989-01-19 PL PL89277261A patent/PL163814B1/en unknown
- 1989-01-19 CA CA000588614A patent/CA1339896C/en not_active Expired - Lifetime
- 1989-01-19 BE BE8900061A patent/BE1003815A4/en active
- 1989-01-19 IE IE15389A patent/IE62275B1/en not_active IP Right Cessation
- 1989-01-19 OA OA59510A patent/OA09031A/en unknown
- 1989-01-19 CH CH172/89A patent/CH679152A5/de not_active IP Right Cessation
- 1989-01-19 PT PT89482A patent/PT89482B/en not_active IP Right Cessation
- 1989-01-19 AT AT0010689A patent/AT397801B/en not_active IP Right Cessation
- 1989-01-19 KR KR1019890000551A patent/KR0127137B1/en not_active IP Right Cessation
- 1989-01-19 NL NL8900122A patent/NL8900122A/en not_active Application Discontinuation
- 1989-01-19 NZ NZ227663A patent/NZ227663A/en unknown
- 1989-01-19 LU LU87437A patent/LU87437A1/en unknown
- 1989-01-19 ES ES8900184A patent/ES2010091A6/en not_active Expired
- 1989-01-20 AU AU28671/89A patent/AU626278B2/en not_active Expired
-
1992
- 1992-01-13 AU AU10180/92A patent/AU637015B2/en not_active Expired
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