GR890100033A - Method for the preparation of dideoxydidehydrocarbocyclic nucleosides - Google Patents

Method for the preparation of dideoxydidehydrocarbocyclic nucleosides

Info

Publication number
GR890100033A
GR890100033A GR890100033A GR890100033A GR890100033A GR 890100033 A GR890100033 A GR 890100033A GR 890100033 A GR890100033 A GR 890100033A GR 890100033 A GR890100033 A GR 890100033A GR 890100033 A GR890100033 A GR 890100033A
Authority
GR
Greece
Prior art keywords
dideoxydidehydrocarbocyclic
nucleosides
preparation
unions
revealed
Prior art date
Application number
GR890100033A
Other languages
Greek (el)
Inventor
Mei Hua
Peter Leslie Myers
Richard Storer
Robert Vince
Original Assignee
Univ Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/146,252 external-priority patent/US4916224A/en
Priority claimed from GB888821011A external-priority patent/GB8821011D0/en
Priority claimed from US07/278,652 external-priority patent/US4931559A/en
Application filed by Univ Minnesota filed Critical Univ Minnesota
Publication of GR890100033A publication Critical patent/GR890100033A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Abstract

Αποκαλύπτονται ενώσεις του τύπουωUnions of the press are revealed

GR890100033A 1988-01-20 1989-01-19 Method for the preparation of dideoxydidehydrocarbocyclic nucleosides GR890100033A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/146,252 US4916224A (en) 1988-01-20 1988-01-20 Dideoxycarbocyclic nucleosides
GB888821011A GB8821011D0 (en) 1988-09-07 1988-09-07 Chemical compounds
US07/278,652 US4931559A (en) 1988-01-20 1988-12-05 Optically-active isomers of dideoxycarbocyclic nucleosides

Publications (1)

Publication Number Publication Date
GR890100033A true GR890100033A (en) 1994-03-31

Family

ID=27264063

Family Applications (1)

Application Number Title Priority Date Filing Date
GR890100033A GR890100033A (en) 1988-01-20 1989-01-19 Method for the preparation of dideoxydidehydrocarbocyclic nucleosides

Country Status (29)

Country Link
JP (1) JP2793825B2 (en)
KR (1) KR0127137B1 (en)
AT (1) AT397801B (en)
AU (2) AU626278B2 (en)
BE (1) BE1003815A4 (en)
CA (1) CA1339896C (en)
CH (1) CH679152A5 (en)
DE (1) DE3901502C2 (en)
DK (1) DK175131B1 (en)
ES (1) ES2010091A6 (en)
FI (1) FI93546C (en)
FR (1) FR2626002B1 (en)
GB (1) GB2217320B (en)
GR (1) GR890100033A (en)
HU (1) HU203755B (en)
IE (1) IE62275B1 (en)
IL (1) IL88999A (en)
IT (1) IT1229531B (en)
LU (1) LU87437A1 (en)
MY (1) MY103801A (en)
NL (1) NL8900122A (en)
NO (1) NO169123C (en)
NZ (1) NZ227663A (en)
OA (1) OA09031A (en)
PL (1) PL163814B1 (en)
PT (1) PT89482B (en)
RU (1) RU2114846C1 (en)
SE (1) SE505213C2 (en)
YU (1) YU47791B (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1215339B (en) * 1987-01-14 1990-02-08 Co Pharma Corp Srl PROCEDURE FOR THE PREPARATION OF 9- (HYDROXIALCHIL) -IPOXANTINE
US5631370A (en) 1988-01-20 1997-05-20 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
GB8815265D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
US4939252A (en) * 1989-04-20 1990-07-03 Hoffmann-La Roche Inc. Novel intermediates for the preparation of Carbovir
WO1991000282A1 (en) * 1989-06-27 1991-01-10 The Wellcome Foundation Limited Therapeutic nucleosides
GB8916480D0 (en) * 1989-07-19 1989-09-06 Glaxo Group Ltd Chemical process
GB8916479D0 (en) * 1989-07-19 1989-09-06 Glaxo Group Ltd Chemical process
GB8916478D0 (en) * 1989-07-19 1989-09-06 Glaxo Group Ltd Chemical process
GB8916477D0 (en) * 1989-07-19 1989-09-06 Glaxo Group Ltd Chemical process
MY104575A (en) * 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.
US5126452A (en) * 1990-04-06 1992-06-30 Glaxo Inc. Synthesis of purine substituted cyclopentene derivatives
US5144034A (en) * 1990-04-06 1992-09-01 Glaxo Inc. Process for the synthesis of cyclopentene derivatives of purines
US5241069A (en) * 1990-04-06 1993-08-31 Glaxo Inc. Carbonate intermediates for the synthesis of purine substituted cyclopentene derivatives
US5057630A (en) * 1990-04-06 1991-10-15 Glaxo Inc. Synthesis of cyclopentene derivatives
GB9108376D0 (en) * 1991-04-19 1991-06-05 Enzymatix Ltd Cyclopentenes
WO1995013277A1 (en) * 1993-11-12 1995-05-18 Merrell Pharmaceuticals Inc. 6-oxo-nucleosides useful as immunosuppressants
GB9721780D0 (en) * 1997-10-14 1997-12-10 Glaxo Group Ltd Process for the synthesis of chloropurine intermediates
EP1124805B1 (en) * 1998-10-30 2003-05-21 Lonza AG Method for producing 4-[(2',5'- diamino-6'- halopyrimidine- 4'-yl)amino]- cyclopent- 2-enylmethanols
DE59905679D1 (en) 1998-10-30 2003-06-26 Lonza Ag METHOD FOR PRODUCING 4 - [(2 ', 5'-DIAMINO-6'-HALOGENPYRIMIDIN-4'-YL) AMINO] -CYCLOPENT-2-ENYLMETHANOLS
TWI229674B (en) * 1998-12-04 2005-03-21 Astra Pharma Prod Novel triazolo[4,5-d]pyrimidine compounds, pharmaceutical composition containing the same, their process for preparation and uses
GB9903091D0 (en) * 1999-02-12 1999-03-31 Glaxo Group Ltd Therapeutic nucleoside compound
AR039540A1 (en) * 2002-05-13 2005-02-23 Tibotec Pharm Ltd MICROBICIDE COMPOUNDS WITH PIRIMIDINE OR TRIAZINE CONTENT
JP7104154B2 (en) 2018-07-27 2022-07-20 富士フイルム株式会社 Cyclopentenylpurine derivative or salt thereof
WO2021191417A1 (en) 2020-03-27 2021-09-30 Som Innovation Biotech, S.A. Compounds for use in the treatment of synucleinopathies

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268672A (en) * 1977-02-09 1981-05-19 The Regents Of The University Of Minnesota Adenosine deaminase resistant antiviral purine nucleosides and method of preparation
US4742064A (en) * 1985-09-10 1988-05-03 Regents Of The University Of Minnesota Antiviral carbocyclic analogs of xylofuranosylpurines
JPS62177234A (en) * 1986-01-30 1987-08-04 Mitsubishi Heavy Ind Ltd Production device of carbon fiber by centrifugal spinning
IN164556B (en) * 1986-03-06 1989-04-08 Takeda Chemical Industries Ltd
NZ229453A (en) * 1988-06-10 1991-08-27 Univ Minnesota & Southern Rese A pharmaceutical composition containing purine derivatives with nucleosides such as azt, as antiviral agents
GB8815265D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
MY104575A (en) * 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.

Also Published As

Publication number Publication date
OA09031A (en) 1991-03-31
SE505213C2 (en) 1997-07-14
HUT48887A (en) 1989-07-28
BE1003815A4 (en) 1992-06-23
AU626278B2 (en) 1992-07-30
NZ227663A (en) 1990-09-26
IL88999A0 (en) 1989-08-15
LU87437A1 (en) 1989-08-30
DK23489D0 (en) 1989-01-19
NO890253L (en) 1989-07-21
IL88999A (en) 1994-12-29
JP2793825B2 (en) 1998-09-03
AU637015B2 (en) 1993-05-13
GB8901187D0 (en) 1989-03-15
IE62275B1 (en) 1995-01-25
JPH02196788A (en) 1990-08-03
AU1018092A (en) 1992-03-12
YU47791B (en) 1996-01-09
DE3901502C2 (en) 2002-06-13
YU12389A (en) 1991-10-31
DK23489A (en) 1989-07-21
PL163814B1 (en) 1994-05-31
NO169123B (en) 1992-02-03
DE3901502A1 (en) 1989-07-27
NL8900122A (en) 1989-08-16
DK175131B1 (en) 2004-06-14
IT8947546A0 (en) 1989-01-19
PT89482A (en) 1989-10-04
AU2867189A (en) 1989-07-20
KR890011902A (en) 1989-08-23
RU2114846C1 (en) 1998-07-10
GB2217320B (en) 1992-04-08
CA1339896C (en) 1998-06-02
FI890286A0 (en) 1989-01-19
PL277261A1 (en) 1989-09-18
SE8900192D0 (en) 1989-01-19
PT89482B (en) 1994-02-28
NO169123C (en) 1992-05-13
SE8900192L (en) 1989-07-21
FI890286A (en) 1989-07-21
FI93546B (en) 1995-01-13
HU203755B (en) 1991-09-30
MY103801A (en) 1993-09-30
IE890153L (en) 1989-07-20
ES2010091A6 (en) 1989-10-16
NO890253D0 (en) 1989-01-19
FI93546C (en) 1995-04-25
IT1229531B (en) 1991-09-04
GB2217320A (en) 1989-10-25
FR2626002A1 (en) 1989-07-21
CH679152A5 (en) 1991-12-31
FR2626002B1 (en) 1994-01-28
AT397801B (en) 1994-07-25
KR0127137B1 (en) 1997-12-29
ATA10689A (en) 1993-11-15

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