IT8947546A0 - NUCLEOSIDE DIDEOXYDEHYDROCARBOCYCLIC COMPOUNDS AND PHARMACEUTICAL FORMULATION THAT CONTAINS THEM - Google Patents

NUCLEOSIDE DIDEOXYDEHYDROCARBOCYCLIC COMPOUNDS AND PHARMACEUTICAL FORMULATION THAT CONTAINS THEM

Info

Publication number
IT8947546A0
IT8947546A0 IT8947546A IT4754689A IT8947546A0 IT 8947546 A0 IT8947546 A0 IT 8947546A0 IT 8947546 A IT8947546 A IT 8947546A IT 4754689 A IT4754689 A IT 4754689A IT 8947546 A0 IT8947546 A0 IT 8947546A0
Authority
IT
Italy
Prior art keywords
dideoxydehydrocarbocyclic
nucleoside
compounds
pharmaceutical formulation
formulation
Prior art date
Application number
IT8947546A
Other languages
Italian (it)
Other versions
IT1229531B (en
Inventor
Vince Robert
Hua Mei
Leslie Myers Peter
Storer Richard
Original Assignee
Univ Minnesota Minneapolis Min
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/146,252 external-priority patent/US4916224A/en
Priority claimed from GB888821011A external-priority patent/GB8821011D0/en
Priority claimed from US07/278,652 external-priority patent/US4931559A/en
Application filed by Univ Minnesota Minneapolis Min filed Critical Univ Minnesota Minneapolis Min
Publication of IT8947546A0 publication Critical patent/IT8947546A0/en
Application granted granted Critical
Publication of IT1229531B publication Critical patent/IT1229531B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
IT8947546A 1988-01-20 1989-01-19 DIDEOXIDE / HYDROCARBOCYCLIC NUCLEOSID COMPOUNDS AND PHARMACEUTICAL FORMULATION CONTAINING THEM IT1229531B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/146,252 US4916224A (en) 1988-01-20 1988-01-20 Dideoxycarbocyclic nucleosides
GB888821011A GB8821011D0 (en) 1988-09-07 1988-09-07 Chemical compounds
US07/278,652 US4931559A (en) 1988-01-20 1988-12-05 Optically-active isomers of dideoxycarbocyclic nucleosides

Publications (2)

Publication Number Publication Date
IT8947546A0 true IT8947546A0 (en) 1989-01-19
IT1229531B IT1229531B (en) 1991-09-04

Family

ID=27264063

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8947546A IT1229531B (en) 1988-01-20 1989-01-19 DIDEOXIDE / HYDROCARBOCYCLIC NUCLEOSID COMPOUNDS AND PHARMACEUTICAL FORMULATION CONTAINING THEM

Country Status (29)

Country Link
JP (1) JP2793825B2 (en)
KR (1) KR0127137B1 (en)
AT (1) AT397801B (en)
AU (2) AU626278B2 (en)
BE (1) BE1003815A4 (en)
CA (1) CA1339896C (en)
CH (1) CH679152A5 (en)
DE (1) DE3901502C2 (en)
DK (1) DK175131B1 (en)
ES (1) ES2010091A6 (en)
FI (1) FI93546C (en)
FR (1) FR2626002B1 (en)
GB (1) GB2217320B (en)
GR (1) GR890100033A (en)
HU (1) HU203755B (en)
IE (1) IE62275B1 (en)
IL (1) IL88999A (en)
IT (1) IT1229531B (en)
LU (1) LU87437A1 (en)
MY (1) MY103801A (en)
NL (1) NL8900122A (en)
NO (1) NO169123C (en)
NZ (1) NZ227663A (en)
OA (1) OA09031A (en)
PL (1) PL163814B1 (en)
PT (1) PT89482B (en)
RU (1) RU2114846C1 (en)
SE (1) SE505213C2 (en)
YU (1) YU47791B (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1215339B (en) * 1987-01-14 1990-02-08 Co Pharma Corp Srl PROCEDURE FOR THE PREPARATION OF 9- (HYDROXIALCHIL) -IPOXANTINE
US5631370A (en) 1988-01-20 1997-05-20 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
GB8815265D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
US4939252A (en) * 1989-04-20 1990-07-03 Hoffmann-La Roche Inc. Novel intermediates for the preparation of Carbovir
ES2136061T3 (en) * 1989-06-27 1999-11-16 Wellcome Found THERAPEUTIC NUCLEOSIDES.
GB8916477D0 (en) * 1989-07-19 1989-09-06 Glaxo Group Ltd Chemical process
GB8916479D0 (en) * 1989-07-19 1989-09-06 Glaxo Group Ltd Chemical process
GB8916478D0 (en) * 1989-07-19 1989-09-06 Glaxo Group Ltd Chemical process
GB8916480D0 (en) * 1989-07-19 1989-09-06 Glaxo Group Ltd Chemical process
MY104575A (en) * 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.
US5144034A (en) * 1990-04-06 1992-09-01 Glaxo Inc. Process for the synthesis of cyclopentene derivatives of purines
US5241069A (en) * 1990-04-06 1993-08-31 Glaxo Inc. Carbonate intermediates for the synthesis of purine substituted cyclopentene derivatives
US5126452A (en) * 1990-04-06 1992-06-30 Glaxo Inc. Synthesis of purine substituted cyclopentene derivatives
US5057630A (en) * 1990-04-06 1991-10-15 Glaxo Inc. Synthesis of cyclopentene derivatives
GB9108376D0 (en) * 1991-04-19 1991-06-05 Enzymatix Ltd Cyclopentenes
KR960705825A (en) * 1993-11-12 1996-11-08 게리 디. 스트리트 6-Oxo-nucleosides useful as immunosuppressants
GB9721780D0 (en) 1997-10-14 1997-12-10 Glaxo Group Ltd Process for the synthesis of chloropurine intermediates
CN1115338C (en) * 1998-10-30 2003-07-23 隆萨股份公司 Method for producing 4[(2',5'-diamino-6'-halopyrimidine-4'-yl) amino]-cyclopent-2-enylmethanols
KR100606625B1 (en) 1998-10-30 2006-07-28 론자 아게 Method for producing 4-[2',5'-diamino-6'-halopyrimidine-4'-ylamino]-cyclopent-2-enylmethanols
TWI229674B (en) 1998-12-04 2005-03-21 Astra Pharma Prod Novel triazolo[4,5-d]pyrimidine compounds, pharmaceutical composition containing the same, their process for preparation and uses
GB9903091D0 (en) * 1999-02-12 1999-03-31 Glaxo Group Ltd Therapeutic nucleoside compound
AR039540A1 (en) 2002-05-13 2005-02-23 Tibotec Pharm Ltd MICROBICIDE COMPOUNDS WITH PIRIMIDINE OR TRIAZINE CONTENT
EP3831388B1 (en) 2018-07-27 2024-02-28 FUJIFILM Corporation Cyclopentenyl purine derivative or salt thereof for use in suppressing adenovirus
WO2021191417A1 (en) 2020-03-27 2021-09-30 Som Innovation Biotech, S.A. Compounds for use in the treatment of synucleinopathies

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268672A (en) * 1977-02-09 1981-05-19 The Regents Of The University Of Minnesota Adenosine deaminase resistant antiviral purine nucleosides and method of preparation
US4742064A (en) * 1985-09-10 1988-05-03 Regents Of The University Of Minnesota Antiviral carbocyclic analogs of xylofuranosylpurines
JPS62177234A (en) * 1986-01-30 1987-08-04 Mitsubishi Heavy Ind Ltd Production device of carbon fiber by centrifugal spinning
IN164556B (en) * 1986-03-06 1989-04-08 Takeda Chemical Industries Ltd
NZ229453A (en) * 1988-06-10 1991-08-27 Univ Minnesota & Southern Rese A pharmaceutical composition containing purine derivatives with nucleosides such as azt, as antiviral agents
GB8815265D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
MY104575A (en) * 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.

Also Published As

Publication number Publication date
DE3901502A1 (en) 1989-07-27
GB2217320A (en) 1989-10-25
ES2010091A6 (en) 1989-10-16
SE8900192L (en) 1989-07-21
FI890286A0 (en) 1989-01-19
JPH02196788A (en) 1990-08-03
PL163814B1 (en) 1994-05-31
NL8900122A (en) 1989-08-16
NO890253L (en) 1989-07-21
SE505213C2 (en) 1997-07-14
KR890011902A (en) 1989-08-23
YU47791B (en) 1996-01-09
JP2793825B2 (en) 1998-09-03
MY103801A (en) 1993-09-30
PT89482A (en) 1989-10-04
LU87437A1 (en) 1989-08-30
OA09031A (en) 1991-03-31
YU12389A (en) 1991-10-31
NO169123C (en) 1992-05-13
AU637015B2 (en) 1993-05-13
PL277261A1 (en) 1989-09-18
PT89482B (en) 1994-02-28
SE8900192D0 (en) 1989-01-19
FI93546B (en) 1995-01-13
HU203755B (en) 1991-09-30
IE62275B1 (en) 1995-01-25
AU2867189A (en) 1989-07-20
FI890286A (en) 1989-07-21
DK23489A (en) 1989-07-21
AU1018092A (en) 1992-03-12
CA1339896C (en) 1998-06-02
GB2217320B (en) 1992-04-08
AU626278B2 (en) 1992-07-30
DK23489D0 (en) 1989-01-19
HUT48887A (en) 1989-07-28
FR2626002A1 (en) 1989-07-21
NZ227663A (en) 1990-09-26
AT397801B (en) 1994-07-25
IL88999A0 (en) 1989-08-15
IT1229531B (en) 1991-09-04
DE3901502C2 (en) 2002-06-13
CH679152A5 (en) 1991-12-31
GB8901187D0 (en) 1989-03-15
NO169123B (en) 1992-02-03
IL88999A (en) 1994-12-29
DK175131B1 (en) 2004-06-14
KR0127137B1 (en) 1997-12-29
FR2626002B1 (en) 1994-01-28
ATA10689A (en) 1993-11-15
FI93546C (en) 1995-04-25
GR890100033A (en) 1994-03-31
IE890153L (en) 1989-07-20
BE1003815A4 (en) 1992-06-23
RU2114846C1 (en) 1998-07-10
NO890253D0 (en) 1989-01-19

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19990128