IL86751A - תכשירי רוקחות המכילים ציקלוספורינים וציקלוספורינים למיניהם - Google Patents

תכשירי רוקחות המכילים ציקלוספורינים וציקלוספורינים למיניהם

Info

Publication number
IL86751A
IL86751A IL8675188A IL8675188A IL86751A IL 86751 A IL86751 A IL 86751A IL 8675188 A IL8675188 A IL 8675188A IL 8675188 A IL8675188 A IL 8675188A IL 86751 A IL86751 A IL 86751A
Authority
IL
Israel
Prior art keywords
residue
cyclosporin
cyclosporins
mebmt
ciclosporin
Prior art date
Application number
IL8675188A
Other languages
English (en)
Other versions
IL86751A0 (en
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878714118A external-priority patent/GB8714118D0/en
Priority claimed from GB878714100A external-priority patent/GB8714100D0/en
Priority claimed from GB878714090A external-priority patent/GB8714090D0/en
Priority claimed from GB878714093A external-priority patent/GB8714093D0/en
Priority claimed from GB878714098A external-priority patent/GB8714098D0/en
Priority claimed from GB878714119A external-priority patent/GB8714119D0/en
Priority claimed from GB878714125A external-priority patent/GB8714125D0/en
Priority claimed from GB878714115A external-priority patent/GB8714115D0/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IL86751A0 publication Critical patent/IL86751A0/xx
Publication of IL86751A publication Critical patent/IL86751A/he

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL8675188A 1987-06-17 1988-06-15 תכשירי רוקחות המכילים ציקלוספורינים וציקלוספורינים למיניהם IL86751A (he)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
GB878714118A GB8714118D0 (en) 1987-06-17 1987-06-17 Organic compounds
GB878714100A GB8714100D0 (en) 1987-06-17 1987-06-17 Organic compounds
GB878714090A GB8714090D0 (en) 1987-06-17 1987-06-17 Organic compounds
GB878714093A GB8714093D0 (en) 1987-06-17 1987-06-17 Organic compounds
GB878714098A GB8714098D0 (en) 1987-06-17 1987-06-17 Organic compounds
GB878714119A GB8714119D0 (en) 1987-06-17 1987-06-17 Organic compounds
GB878714125A GB8714125D0 (en) 1987-06-17 1987-06-17 Organic compounds
GB878714115A GB8714115D0 (en) 1987-06-17 1987-06-17 Organic compounds

Publications (2)

Publication Number Publication Date
IL86751A0 IL86751A0 (en) 1988-11-30
IL86751A true IL86751A (he) 1994-02-27

Family

ID=27571252

Family Applications (1)

Application Number Title Priority Date Filing Date
IL8675188A IL86751A (he) 1987-06-17 1988-06-15 תכשירי רוקחות המכילים ציקלוספורינים וציקלוספורינים למיניהם

Country Status (21)

Country Link
US (1) US5525590A (he)
EP (1) EP0296122B1 (he)
JP (2) JPH0832724B2 (he)
KR (1) KR970010927B1 (he)
AT (1) ATE95193T1 (he)
AU (1) AU614086B2 (he)
CA (1) CA1338728C (he)
CY (1) CY1939A (he)
CZ (1) CZ411791A3 (he)
DE (1) DE3884470T2 (he)
DK (1) DK173873B1 (he)
ES (1) ES2059558T3 (he)
HK (1) HK152796A (he)
HU (1) HU211678A9 (he)
IE (1) IE62482B1 (he)
IL (1) IL86751A (he)
MY (1) MY103582A (he)
NZ (1) NZ225041A (he)
PT (1) PT87745B (he)
SA (1) SA97170746A (he)
SK (1) SK411791A3 (he)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
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US5236899A (en) * 1987-11-16 1993-08-17 Merck & Co., Inc. 6-position cyclosporin a analogs as modifiers of cytotoxic drug resistance
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
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US5122511A (en) * 1990-02-27 1992-06-16 Merck & Co., Inc. Immunosuppressive cyclosporin analogs with modified amino acids at position-8
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
GB9204466D0 (en) * 1992-03-02 1992-04-15 Sandoz Ltd Improvements in or relating to organic compounds
GB9208712D0 (en) * 1992-04-22 1992-06-10 Sandoz Ltd Pharmaceutical compositions containing cyclosporin derivates
WO1993023010A1 (en) 1992-05-13 1993-11-25 Sandoz Ltd. Ophthalmic compositions containing a cyclosporin
SK278290B6 (en) * 1992-09-07 1996-08-07 Milan Stuchlik Medicaments with n-methylated cyclic undecapeptides
ES2168271T3 (es) 1992-09-25 2002-06-16 Novartis Ag Composiciones farmaceuticas que contienen ciclosporinas.
US20020099067A1 (en) * 1993-07-08 2002-07-25 Ulrich Posanski Pharmaceutical compositions for sparingly soluble therapeutic agents
US6187547B1 (en) 1993-09-08 2001-02-13 Novartis Ag Assay kit
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US6334997B1 (en) * 1994-03-25 2002-01-01 Isotechnika, Inc. Method of using deuterated calcium channel blockers
KR20040068613A (ko) * 1994-03-25 2004-07-31 이소테크니카 인코포레이티드 중수소화된 화합물 이를 포함하는 고혈압 치료용 조성물
EP0789580B1 (de) 1994-11-03 2002-06-05 Novartis AG Neue zubereitungsformen des cyclosporins zur oralen applikation mit einfacher zusammensetzung und hoher bioverfügbarkeit und verfahren zu deren herstellung
GR1002687B (el) * 1995-04-17 1997-05-06 Novartis Ag (Novartis Sa) (Novartis Inc.) Διαδικασια παραγωγης.
US6395770B1 (en) 1995-10-26 2002-05-28 Baker Norton Pharmaceuticals, Inc. Method and compositions for administering taxanes orally to human patients
US6245805B1 (en) * 1995-10-26 2001-06-12 Baker Norton Pharmaceuticals, Inc. Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents
DE19544507B4 (de) 1995-11-29 2007-11-15 Novartis Ag Cyclosporin enthaltende Präparate
GB9601120D0 (en) * 1996-01-19 1996-03-20 Sandoz Ltd Organic compounds
ES2229473T3 (es) 1997-01-30 2005-04-16 Novartis Ag Composiciones farmaceuticas sin aceite que contienen ciclosporina a.
US20030220234A1 (en) * 1998-11-02 2003-11-27 Selvaraj Naicker Deuterated cyclosporine analogs and their use as immunodulating agents
ATE314388T1 (de) * 1997-10-08 2006-01-15 Isotechnika Inc Deuterierte und undeuterierte cyclosporin-analoga und ihre verwendung als immunmodulierende agentien
US6201165B1 (en) 1997-10-16 2001-03-13 Board Of Regents, University Of Texas System Transgenic animal models for cardiac hypertrophy and methods of use thereof
EP1091975B1 (fr) 1998-07-01 2005-12-14 Debiopharm S.A. Nouvelle cyclosporine ayant un profil d'activite ameliore
NZ512599A (en) 1998-12-30 2003-10-31 Dexcel Ltd Formulation for cyclosporin administration featuring a hydrophilic solvent and a surfactant with a HLB of less than 5
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CH614931A5 (he) * 1975-11-04 1979-12-28 Sandoz Ag
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GB8407618D0 (en) * 1984-03-23 1984-05-02 Sandoz Ltd Organic compounds
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Also Published As

Publication number Publication date
SA97170746A (ar) 2005-12-03
JPH0832724B2 (ja) 1996-03-29
AU1767988A (en) 1988-12-22
IL86751A0 (en) 1988-11-30
ES2059558T3 (es) 1994-11-16
HU211678A9 (en) 1995-12-28
CZ411791A3 (en) 1993-02-17
MY103582A (en) 1993-08-28
PT87745B (pt) 1992-10-30
CY1939A (en) 1997-05-16
DK326588D0 (da) 1988-06-15
EP0296122A3 (en) 1990-06-20
DK326588A (da) 1988-12-18
AU614086B2 (en) 1991-08-22
KR890000519A (ko) 1989-03-15
PT87745A (pt) 1988-07-01
DE3884470T2 (de) 1994-03-10
IE62482B1 (en) 1995-02-08
JPH0848696A (ja) 1996-02-20
NZ225041A (en) 1991-03-26
DE3884470D1 (de) 1993-11-04
EP0296122A2 (en) 1988-12-21
JPS6445396A (en) 1989-02-17
SK411791A3 (en) 1995-07-11
CA1338728C (en) 1996-11-19
IE881807L (en) 1988-12-17
HK152796A (en) 1996-08-16
US5525590A (en) 1996-06-11
DK173873B1 (da) 2002-01-21
ATE95193T1 (de) 1993-10-15
KR970010927B1 (ko) 1997-07-02
EP0296122B1 (en) 1993-09-29
JP2772372B2 (ja) 1998-07-02

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