IL85671A - A multi-part differential computing device that uses light scattering methods - Google Patents
A multi-part differential computing device that uses light scattering methodsInfo
- Publication number
- IL85671A IL85671A IL8567188A IL8567188A IL85671A IL 85671 A IL85671 A IL 85671A IL 8567188 A IL8567188 A IL 8567188A IL 8567188 A IL8567188 A IL 8567188A IL 85671 A IL85671 A IL 85671A
- Authority
- IL
- Israel
- Prior art keywords
- light
- signal
- cell
- lymphocytes
- differentiating
- Prior art date
Links
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
- G01N21/53—Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
- G01N2015/016—White blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1019—Associating Coulter-counter and optical flow cytometer [OFC]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1024—Counting particles by non-optical means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
- G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
- G01N2015/139—Measuring the ratio of AC/DC impedances
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
- G01N2015/1413—Hydrodynamic focussing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1477—Multiparameters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N2021/4704—Angular selective
- G01N2021/4711—Multiangle measurement
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2544287A | 1987-03-13 | 1987-03-13 | |
US12995487A | 1987-12-04 | 1987-12-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL85671A0 IL85671A0 (en) | 1988-08-31 |
IL85671A true IL85671A (en) | 1995-12-31 |
Family
ID=26699741
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL8567188A IL85671A (en) | 1987-03-13 | 1988-03-08 | A multi-part differential computing device that uses light scattering methods |
Country Status (11)
Country | Link |
---|---|
US (1) | US5125737A (fr) |
EP (1) | EP0311655B1 (fr) |
JP (1) | JP2505873B2 (fr) |
KR (1) | KR970007077B1 (fr) |
CN (1) | CN1014742B (fr) |
AU (2) | AU602207B2 (fr) |
CA (1) | CA1315125C (fr) |
DE (1) | DE3852270T2 (fr) |
ES (1) | ES2009188A6 (fr) |
IL (1) | IL85671A (fr) |
WO (1) | WO1988007198A1 (fr) |
Families Citing this family (159)
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EP0558632B1 (fr) * | 1990-11-23 | 2000-08-16 | Coulter Corporation | Procede et appareil pour le triage de cellules microscopiques par les techniques de diffusion de la lumiere |
US5247188A (en) * | 1992-01-23 | 1993-09-21 | High Yield Technology | Concentrator funnel for vacuum line particle monitors |
US6509192B1 (en) * | 1992-02-24 | 2003-01-21 | Coulter International Corp. | Quality control method |
US5371585A (en) * | 1992-11-10 | 1994-12-06 | Pacific Scientific Company | Particle detecting instrument with sapphire detecting cell defining a rectangular flow path |
DE69434942T2 (de) * | 1993-02-25 | 2007-11-29 | Abbott Laboratories, Abbott Park | Mehrzweckreagenzsystem zur schnellen lysierung von vollblutproben |
US5534999A (en) * | 1993-03-05 | 1996-07-09 | Shinmikuni Kikai Ltd. | Monitoring sub-micron particles |
AU6830894A (en) * | 1993-05-14 | 1994-12-12 | Coulter Corporation | Reticulocyte analyzing method and apparatus utilizing light scatter techniques |
US5576185A (en) | 1994-04-15 | 1996-11-19 | Coulter Corporation | Method of positive or negative selection of a population or subpopulation of a sample utilizing particles and gravity sedimentation |
JP3355038B2 (ja) * | 1994-08-03 | 2002-12-09 | シスメックス株式会社 | 白血球分類方法 |
JP3375203B2 (ja) * | 1994-08-08 | 2003-02-10 | シスメックス株式会社 | 細胞分析装置 |
US5879900A (en) * | 1994-12-15 | 1999-03-09 | Abbott Laboratories | Method for simultaneous analysis of cell viability, nucleated red blood cells and white blood cell differentials |
US5559037A (en) * | 1994-12-15 | 1996-09-24 | Abbott Laboratories | Method for rapid and simultaneous analysis of nucleated red blood cells |
US5843608A (en) * | 1995-06-08 | 1998-12-01 | Coulter International Corp. | Reagent and method for differential determination of leukocytes in blood |
US5686308A (en) * | 1995-06-08 | 1997-11-11 | Coulter Corporation | Reagent and method for differential determination of leukocytes in blood |
US5882933A (en) * | 1995-06-08 | 1999-03-16 | Coulter International Corp. | Method for determination of leukocytes and hemoglobin concentration in blood |
US5786224A (en) * | 1995-06-29 | 1998-07-28 | Coulter Corporation | Reagent and method for differential determination of leukocytes in blood |
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US5686309A (en) * | 1996-01-19 | 1997-11-11 | Coulter International Corp. | Method and apparatus for determination of hemoglobin content of individual red blood cells |
JP4136017B2 (ja) * | 1996-09-19 | 2008-08-20 | シスメックス株式会社 | 粒子分析装置 |
US6175227B1 (en) | 1997-07-03 | 2001-01-16 | Coulter International Corp. | Potential-sensing method and apparatus for sensing and characterizing particles by the Coulter principle |
US5945293A (en) * | 1997-10-09 | 1999-08-31 | Coulter International Corp. | Protein-colloidal metal-aminodextran coated particle and methods of preparation and use |
US5874310A (en) * | 1997-11-21 | 1999-02-23 | Coulter International Corp. | Method for differentiation of nucleated red blood cells |
US5874311A (en) * | 1997-11-21 | 1999-02-23 | Coulter International Corp. | Method for differentiation of reticulocytes in blood |
US5917584A (en) * | 1997-11-21 | 1999-06-29 | Coulter International Corp. | Method for differentiation of nucleated red blood cells |
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WO1999046047A2 (fr) * | 1998-03-10 | 1999-09-16 | Large Scale Proteomics Corporation | Detection et caracterisation des micro-organismes |
FR2779296B1 (fr) * | 1998-06-02 | 2000-08-18 | France Telecom | Dispositif pour l'emission ou la reception d'un signal crypte par chaos deterministe |
JP4101994B2 (ja) * | 1999-01-21 | 2008-06-18 | シスメックス株式会社 | 粒子分析装置および自動粒子分析方法 |
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US6323632B1 (en) * | 1999-08-13 | 2001-11-27 | Coulter International Corp. | Solid state RF oscillator-detector for flow cytometer |
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JP3817091B2 (ja) * | 1999-07-02 | 2006-08-30 | テルモ株式会社 | 細胞数測定装置 |
US6232125B1 (en) | 1999-08-09 | 2001-05-15 | Coulter International Corp. | Method and apparatus for differentiating and enumerating leukocytes |
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EP2258172B1 (fr) | 2000-05-09 | 2017-04-19 | Xy, Llc | Cytométre de flux pour différencier des populations de spermatozoïdes portant un chromosome X et un chromosome Y |
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JP4708605B2 (ja) * | 2000-07-24 | 2011-06-22 | シスメックス株式会社 | 粒子分析装置とその粒子分画方法 |
US8354647B2 (en) * | 2000-11-08 | 2013-01-15 | University Of North Florida | Photoelectric chemical sensor and sensing method utilizing interfacial photo-voltages |
BRPI0115791B1 (pt) | 2000-11-29 | 2020-05-05 | Colorado State Univ | sistema para fertilização in vitro com espematozóides separados em populações portadoras de cromossoma x e cromossoma y |
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-
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- 1988-03-04 KR KR1019880701385A patent/KR970007077B1/ko not_active IP Right Cessation
- 1988-03-08 IL IL8567188A patent/IL85671A/en not_active IP Right Cessation
- 1988-03-11 CA CA000561233A patent/CA1315125C/fr not_active Expired - Fee Related
- 1988-03-11 ES ES8800748A patent/ES2009188A6/es not_active Expired
- 1988-03-12 CN CN88101232A patent/CN1014742B/zh not_active Expired
- 1988-03-14 WO PCT/US1988/000753 patent/WO1988007198A1/fr active IP Right Grant
- 1988-03-14 AU AU14970/88A patent/AU602207B2/en not_active Expired
- 1988-03-14 JP JP63502800A patent/JP2505873B2/ja not_active Expired - Lifetime
- 1988-03-14 DE DE3852270T patent/DE3852270T2/de not_active Expired - Lifetime
- 1988-03-14 EP EP88903074A patent/EP0311655B1/fr not_active Expired - Lifetime
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1990
- 1990-02-13 US US07/479,199 patent/US5125737A/en not_active Expired - Lifetime
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AU1497088A (en) | 1988-10-10 |
CA1315125C (fr) | 1993-03-30 |
AU632393B2 (en) | 1992-12-24 |
CN1014742B (zh) | 1991-11-13 |
EP0311655B1 (fr) | 1994-11-30 |
DE3852270D1 (de) | 1995-01-12 |
AU602207B2 (en) | 1990-10-04 |
JP2505873B2 (ja) | 1996-06-12 |
WO1988007198A1 (fr) | 1988-09-22 |
DE3852270T2 (de) | 1995-04-06 |
CN1031422A (zh) | 1989-03-01 |
EP0311655A4 (en) | 1990-09-05 |
KR970007077B1 (ko) | 1997-05-02 |
JPH01502533A (ja) | 1989-08-31 |
ES2009188A6 (es) | 1989-09-01 |
EP0311655A1 (fr) | 1989-04-19 |
US5125737A (en) | 1992-06-30 |
KR890700829A (ko) | 1989-04-27 |
IL85671A0 (en) | 1988-08-31 |
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