IL73639A - Crystalline cephalexin hydrochloride monohydrate,process for its preparation and a pharmaceutical composition containing it - Google Patents

Crystalline cephalexin hydrochloride monohydrate,process for its preparation and a pharmaceutical composition containing it

Info

Publication number
IL73639A
IL73639A IL73639A IL7363984A IL73639A IL 73639 A IL73639 A IL 73639A IL 73639 A IL73639 A IL 73639A IL 7363984 A IL7363984 A IL 7363984A IL 73639 A IL73639 A IL 73639A
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical composition
composition containing
hydrochloride monohydrate
cephalexin hydrochloride
Prior art date
Application number
IL73639A
Other languages
English (en)
Other versions
IL73639A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL73639A0 publication Critical patent/IL73639A0/xx
Publication of IL73639A publication Critical patent/IL73639A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/227-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IL73639A 1983-12-01 1984-11-26 Crystalline cephalexin hydrochloride monohydrate,process for its preparation and a pharmaceutical composition containing it IL73639A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/556,887 US4600773A (en) 1983-12-01 1983-12-01 Crystalline cephalexin hydrochloride monohydrate

Publications (2)

Publication Number Publication Date
IL73639A0 IL73639A0 (en) 1985-02-28
IL73639A true IL73639A (en) 1988-06-30

Family

ID=24223233

Family Applications (1)

Application Number Title Priority Date Filing Date
IL73639A IL73639A (en) 1983-12-01 1984-11-26 Crystalline cephalexin hydrochloride monohydrate,process for its preparation and a pharmaceutical composition containing it

Country Status (46)

Country Link
US (1) US4600773A (ar)
EP (1) EP0143658B1 (ar)
JP (1) JPS60132990A (ar)
KR (1) KR870000527B1 (ar)
AT (1) AT390616B (ar)
AU (1) AU566080B2 (ar)
BE (1) BE901142A (ar)
BG (1) BG40966A3 (ar)
BR (1) BR8406037A (ar)
CH (1) CH661732A5 (ar)
CS (1) CS248725B2 (ar)
CY (1) CY1505A (ar)
DD (1) DD229410A5 (ar)
DE (1) DE3443065A1 (ar)
DK (1) DK158354C (ar)
ES (1) ES538019A0 (ar)
FI (1) FI80274C (ar)
FR (1) FR2555990B1 (ar)
GB (1) GB2150566B (ar)
GR (1) GR81043B (ar)
GT (1) GT198400146A (ar)
HK (1) HK92089A (ar)
HU (1) HU192516B (ar)
IE (1) IE57886B1 (ar)
IL (1) IL73639A (ar)
IN (1) IN163078B (ar)
IT (1) IT1177329B (ar)
JO (1) JO1347B1 (ar)
LU (1) LU85650A1 (ar)
MA (1) MA20279A1 (ar)
MX (1) MX159670A (ar)
MY (1) MY102966A (ar)
NL (1) NL8403588A (ar)
NO (1) NO844711L (ar)
NZ (1) NZ210357A (ar)
OA (1) OA07876A (ar)
PH (1) PH20849A (ar)
PL (1) PL146014B1 (ar)
PT (1) PT79553B (ar)
SE (1) SE464026B (ar)
SG (1) SG59789G (ar)
SU (1) SU1251807A3 (ar)
YU (1) YU45680B (ar)
ZA (1) ZA849224B (ar)
ZM (1) ZM6384A1 (ar)
ZW (1) ZW19084A1 (ar)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2555989B1 (fr) * 1983-12-06 1987-02-20 Bristol Myers Sa Monohydrate de chlorocephadroxyle
JPS60142987A (ja) * 1983-12-29 1985-07-29 Mochida Pharmaceut Co Ltd セフアロスポリン誘導体
DE3485860T2 (de) * 1983-12-29 1993-01-14 Mochida Pharm Co Ltd Cephalosporinverbindungen, verfahren zu ihrer herstellung und pharmazeutishe praeparate.
US4840945A (en) * 1985-04-01 1989-06-20 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
US4775751A (en) * 1985-06-03 1988-10-04 Eli Lilly & Company Process for cephalexin hydrochloride alcoholates
US4880798A (en) * 1986-11-25 1989-11-14 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
JPS63132893A (ja) * 1986-11-25 1988-06-04 Mochida Pharmaceut Co Ltd 新規セフアロスポリン誘導体、その製法およびそれらを有効成分とする抗菌剤
US5721229A (en) * 1995-12-26 1998-02-24 Veterinary Pharmacy Corporation Soluble forms of cephalosporins and treatment of animals
GB9717629D0 (en) 1997-08-21 1997-10-22 Johnson Matthey Plc Removal of residual organic solvents
AT413282B (de) * 2002-02-01 2006-01-15 Sandoz Ag Kristalline salze der 7-(((5-amino-1,2,4-thiadiazol-3-yl) (fluoromethoxy-imino)acetyl)amino)-3- ((imino-1-piperazinylmethyl)
US20040033262A1 (en) * 2002-08-19 2004-02-19 Orchid Health Care Sustained release pharmaceutical composition of a cephalosporin antibiotic

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3507861A (en) * 1966-09-14 1970-04-21 Lilly Co Eli Certain 3-methyl-cephalosporin compounds
US3655656A (en) * 1970-06-04 1972-04-11 Lilly Co Eli Crystalline cephalexin monohydrate
DE2317179C2 (de) * 1973-04-05 1982-11-25 Bristol-Myers Co., 10154 New York, N.Y. Verfahren zur Herstellung der relativ wasserunlöslichen kristallinen Form von Cefalexinmonohydrat
US3985747A (en) * 1974-05-24 1976-10-12 Bristol-Myers Company Crystalline sesquihydrate of 7-[D-α-amino-α-(p-hydroxyphenyl)acetamido]-3-(1,2,3-triazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid
JPS50151890A (ar) * 1974-05-30 1975-12-06
CH642850A5 (it) * 1978-10-20 1984-05-15 Ausonia Farma Srl Composizioni farmaceutiche ad attivita antibatterica contro infezioni da germi gram-positivi e gram-negativi.
NZ206600A (en) * 1983-05-11 1987-01-23 Alza Corp Osmotic drug delivery device

Also Published As

Publication number Publication date
FR2555990A1 (fr) 1985-06-07
FI80274B (fi) 1990-01-31
KR850004765A (ko) 1985-07-27
ZM6384A1 (en) 1985-07-22
YU45680B (sh) 1992-07-20
SE8405954D0 (sv) 1984-11-26
AU3589784A (en) 1985-06-06
EP0143658A3 (en) 1986-02-12
CH661732A5 (de) 1987-08-14
NZ210357A (en) 1988-05-30
AU566080B2 (en) 1987-10-08
FI80274C (fi) 1990-05-10
OA07876A (fr) 1986-11-20
HUT35685A (en) 1985-07-29
JO1347B1 (ar) 1986-11-30
MA20279A1 (fr) 1985-07-01
DK158354C (da) 1990-10-01
PL250593A1 (en) 1985-07-30
IN163078B (ar) 1988-08-06
JPS60132990A (ja) 1985-07-16
EP0143658B1 (en) 1989-03-22
SG59789G (en) 1989-12-29
ATA373284A (de) 1989-11-15
MY102966A (en) 1993-03-31
DK561284A (da) 1985-06-02
PT79553A (en) 1984-12-01
IT8423746A0 (it) 1984-11-27
BR8406037A (pt) 1985-08-27
IT8423746A1 (it) 1986-05-27
IE843033L (en) 1985-06-01
NO844711L (no) 1985-06-03
YU199684A (en) 1987-02-28
ZW19084A1 (en) 1985-06-12
HK92089A (en) 1989-11-24
BG40966A3 (en) 1987-03-14
GB8430073D0 (en) 1985-01-09
NL8403588A (nl) 1985-07-01
AT390616B (de) 1990-06-11
FI844631L (fi) 1985-06-02
US4600773A (en) 1986-07-15
DE3443065C2 (ar) 1989-03-23
JPH0548234B2 (ar) 1993-07-20
ES8602011A1 (es) 1985-11-01
MX159670A (es) 1989-08-02
FI844631A0 (fi) 1984-11-26
DD229410A5 (de) 1985-11-06
FR2555990B1 (fr) 1986-12-26
SU1251807A3 (ru) 1986-08-15
ZA849224B (en) 1986-07-30
SE8405954L (sv) 1985-06-02
GB2150566A (en) 1985-07-03
EP0143658A2 (en) 1985-06-05
SE464026B (sv) 1991-02-25
DE3443065A1 (de) 1985-06-20
GB2150566B (en) 1987-08-26
GR81043B (en) 1985-03-27
LU85650A1 (fr) 1985-07-17
PH20849A (en) 1987-05-08
DK561284D0 (da) 1984-11-27
IE57886B1 (en) 1993-05-05
CS248725B2 (en) 1987-02-12
GT198400146A (es) 1986-05-20
DK158354B (da) 1990-05-07
PL146014B1 (en) 1988-12-31
PT79553B (en) 1986-12-15
CY1505A (en) 1990-08-03
IT1177329B (it) 1987-08-26
KR870000527B1 (ko) 1987-03-14
HU192516B (en) 1987-06-29
IL73639A0 (en) 1985-02-28
ES538019A0 (es) 1985-11-01
BE901142A (fr) 1985-05-28

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Legal Events

Date Code Title Description
RH Patent void