IL66518A - 2-(2'-hydroxy-3'-(1,1-dimethylpropylamino)-propoxy)beta-phenylpropiophenone,its acid addition salts,process for its preparation and pharmaceutical compositions - Google Patents
2-(2'-hydroxy-3'-(1,1-dimethylpropylamino)-propoxy)beta-phenylpropiophenone,its acid addition salts,process for its preparation and pharmaceutical compositionsInfo
- Publication number
- IL66518A IL66518A IL66518A IL6651882A IL66518A IL 66518 A IL66518 A IL 66518A IL 66518 A IL66518 A IL 66518A IL 6651882 A IL6651882 A IL 6651882A IL 66518 A IL66518 A IL 66518A
- Authority
- IL
- Israel
- Prior art keywords
- acid addition
- addition salts
- phenylpropiophenone
- dimethylpropylamino
- propoxy
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 4
- 150000003839 salts Chemical class 0.000 title abstract 4
- QGGZBXOADPVUPN-UHFFFAOYSA-N dihydrochalcone Chemical compound C=1C=CC=CC=1C(=O)CCC1=CC=CC=C1 QGGZBXOADPVUPN-UHFFFAOYSA-N 0.000 title 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- OSVOQDOCGKKCPJ-UHFFFAOYSA-N 2-[2-hydroxy-3-(2-methylbutan-2-ylamino)propoxy]-1,3-diphenylpropan-1-one Chemical compound C=1C=CC=CC=1C(=O)C(OCC(O)CNC(C)(C)CC)CC1=CC=CC=C1 OSVOQDOCGKKCPJ-UHFFFAOYSA-N 0.000 abstract 1
- 230000033764 rhythmic process Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
- C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
- C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
- C07C217/36—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by carbon atoms having at least two bonds to oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3133814A DE3133814C2 (de) | 1981-08-25 | 1981-08-25 | 2-[2'-Hydroxy-3'-(1,1-dimethylpropylamino)-propoxy]-β-phenylpropiophenon, seine Säureadditionssalze und Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL66518A true IL66518A (en) | 1985-09-29 |
Family
ID=6140190
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL66518A IL66518A (en) | 1981-08-25 | 1982-08-11 | 2-(2'-hydroxy-3'-(1,1-dimethylpropylamino)-propoxy)beta-phenylpropiophenone,its acid addition salts,process for its preparation and pharmaceutical compositions |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4460605A (en, 2012) |
| EP (1) | EP0074014B1 (en, 2012) |
| JP (1) | JPS58501324A (en, 2012) |
| KR (1) | KR870000957B1 (en, 2012) |
| AT (1) | ATE8129T1 (en, 2012) |
| AU (1) | AU555818B2 (en, 2012) |
| CA (1) | CA1192224A (en, 2012) |
| CS (1) | CS241511B2 (en, 2012) |
| DD (1) | DD211783A5 (en, 2012) |
| DE (2) | DE3133814C2 (en, 2012) |
| DK (1) | DK156430C (en, 2012) |
| ES (1) | ES515222A0 (en, 2012) |
| FI (1) | FI71123C (en, 2012) |
| GR (1) | GR77591B (en, 2012) |
| HU (1) | HU193523B (en, 2012) |
| IL (1) | IL66518A (en, 2012) |
| NO (1) | NO155880C (en, 2012) |
| PL (1) | PL135591B1 (en, 2012) |
| PT (1) | PT75460B (en, 2012) |
| RO (1) | RO87061B (en, 2012) |
| SU (1) | SU1331424A3 (en, 2012) |
| WO (1) | WO1983000688A1 (en, 2012) |
| YU (1) | YU42792B (en, 2012) |
| ZA (1) | ZA826025B (en, 2012) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3226863A1 (de) * | 1981-09-18 | 1983-04-07 | Basf Ag, 6700 Ludwigshafen | Aminopropanolderivate von 2-hydroxy-ss-phenyl-propiophenonen, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel |
| DE3309595A1 (de) * | 1983-03-17 | 1984-09-20 | Basf Ag, 6700 Ludwigshafen | Neue aminopropanolderivate von 1-(2-hydroxy-phenyl)-3-phenyl-propanolen, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel |
| DE3328376A1 (de) | 1983-07-21 | 1985-01-31 | Helopharm W. Petrik & Co Kg, 1000 Berlin | Aminopropanolderivate von 2-hydroxy-ss-phenyl-propiophenonen, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
| DE3348170C2 (en, 2012) * | 1983-07-21 | 1993-03-11 | Helopharm W. Petrik Gmbh & Co Kg, 1000 Berlin, De | |
| DE3343671A1 (de) * | 1983-12-02 | 1985-06-20 | Basf Ag, 6700 Ludwigshafen | Aminopropanolderivate von substituierten 2-hydroxy-propiophenonen, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel |
| US5095151A (en) * | 1985-05-21 | 1992-03-10 | American Home Products Corporation | Preparation of propranolol hydrochloride macrocrystals |
| DE3725273A1 (de) * | 1987-07-30 | 1989-02-09 | Basf Ag | Verfahren zur synthese von enantiomeren des propafenons sowie diese enthaltende therapeutische mittel |
| US4954347A (en) * | 1988-05-03 | 1990-09-04 | Basf K & F Corp. | Long lasting composition of propafenone and quinidine for treatment of cardiac conditions |
| DE3907512C2 (de) * | 1989-03-08 | 1997-08-14 | Laevosan Gmbh & Co Kg | Neue Aryloxy-alkylamine, deren Herstellung und diese enthaltende Arzneimittel |
| DE3911069A1 (de) * | 1989-04-06 | 1990-10-11 | Knoll Ag | Einkristalle von ss-phenylpropiophenonen |
| DE4000213A1 (de) * | 1990-01-05 | 1991-07-11 | Helopharm Petrik Co Kg | O-hydroxy-ss-(1-naphthyl)-propiophenonderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| US6168615B1 (en) | 1998-05-04 | 2001-01-02 | Micrus Corporation | Method and apparatus for occlusion and reinforcement of aneurysms |
| EP2546410B1 (en) | 2011-07-11 | 2013-11-13 | Omya International AG | Hydrophobised calcium carbonate particles |
| CN104262178A (zh) * | 2014-09-28 | 2015-01-07 | 常州瑞明药业有限公司 | 盐酸普罗帕酮的合成方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2001431C3 (de) * | 1970-01-06 | 1974-12-12 | Helopharm W. Petrik & Co Kg, 1000 Berlin | 2-(2'-Hydroxy-3'-alkylaminopropoxy)-Omega-phenyl-propiophenone und Verfahren zur Herstellung derselben |
-
1981
- 1981-08-25 DE DE3133814A patent/DE3133814C2/de not_active Expired
-
1982
- 1982-08-11 IL IL66518A patent/IL66518A/xx not_active IP Right Cessation
- 1982-08-12 AU AU87113/82A patent/AU555818B2/en not_active Ceased
- 1982-08-18 KR KR8203707A patent/KR870000957B1/ko not_active Expired
- 1982-08-19 ZA ZA826025A patent/ZA826025B/xx unknown
- 1982-08-23 PL PL1982238012A patent/PL135591B1/pl unknown
- 1982-08-23 DD DD82250311A patent/DD211783A5/de unknown
- 1982-08-24 EP EP82107750A patent/EP0074014B1/de not_active Expired
- 1982-08-24 JP JP57502643A patent/JPS58501324A/ja active Granted
- 1982-08-24 AT AT82107750T patent/ATE8129T1/de not_active IP Right Cessation
- 1982-08-24 WO PCT/EP1982/000180 patent/WO1983000688A1/en active IP Right Grant
- 1982-08-24 CS CS826167A patent/CS241511B2/cs unknown
- 1982-08-24 DE DE8282107750T patent/DE3260301D1/de not_active Expired
- 1982-08-24 US US06/410,933 patent/US4460605A/en not_active Expired - Lifetime
- 1982-08-24 PT PT75460A patent/PT75460B/pt not_active IP Right Cessation
- 1982-08-24 ES ES515222A patent/ES515222A0/es active Granted
- 1982-08-24 GR GR69096A patent/GR77591B/el unknown
- 1982-08-24 HU HU823093A patent/HU193523B/hu not_active IP Right Cessation
- 1982-08-24 YU YU1907/82A patent/YU42792B/xx unknown
- 1982-08-25 CA CA000410054A patent/CA1192224A/en not_active Expired
-
1983
- 1983-04-15 NO NO83831339A patent/NO155880C/no unknown
- 1983-04-21 RO RO110735A patent/RO87061B/ro unknown
- 1983-04-22 SU SU833583671A patent/SU1331424A3/ru active
- 1983-04-22 FI FI831388A patent/FI71123C/fi not_active IP Right Cessation
- 1983-04-22 DK DK178883A patent/DK156430C/da not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| RH | Patent void |