IL296875A - Fat-wrapped gas microsphere preparations and related methods - Google Patents

Fat-wrapped gas microsphere preparations and related methods

Info

Publication number
IL296875A
IL296875A IL296875A IL29687522A IL296875A IL 296875 A IL296875 A IL 296875A IL 296875 A IL296875 A IL 296875A IL 29687522 A IL29687522 A IL 29687522A IL 296875 A IL296875 A IL 296875A
Authority
IL
Israel
Prior art keywords
composition
container
lipid
chamber
glycerol
Prior art date
Application number
IL296875A
Other languages
English (en)
Hebrew (he)
Original Assignee
Lantheus Medical Imaging Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lantheus Medical Imaging Inc filed Critical Lantheus Medical Imaging Inc
Publication of IL296875A publication Critical patent/IL296875A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/225—Microparticles, microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Acoustics & Sound (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
IL296875A 2014-12-31 2015-12-28 Fat-wrapped gas microsphere preparations and related methods IL296875A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462098453P 2014-12-31 2014-12-31
PCT/US2015/067615 WO2016109400A2 (en) 2014-12-31 2015-12-28 Lipid-encapsulated gas microsphere compositions and related methods

Publications (1)

Publication Number Publication Date
IL296875A true IL296875A (en) 2022-12-01

Family

ID=56285147

Family Applications (2)

Application Number Title Priority Date Filing Date
IL296875A IL296875A (en) 2014-12-31 2015-12-28 Fat-wrapped gas microsphere preparations and related methods
IL252705A IL252705B2 (en) 2014-12-31 2015-12-28 Fat-wrapped gas microsphere preparations and related methods

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL252705A IL252705B2 (en) 2014-12-31 2015-12-28 Fat-wrapped gas microsphere preparations and related methods

Country Status (16)

Country Link
US (5) US10583207B2 (enExample)
EP (2) EP3240579B1 (enExample)
JP (3) JP6728186B2 (enExample)
KR (2) KR102618877B1 (enExample)
CN (2) CN107206111B (enExample)
AU (2) AU2015374286B2 (enExample)
BR (1) BR112017013787A2 (enExample)
CA (1) CA2972423A1 (enExample)
EA (1) EA201791437A1 (enExample)
ES (1) ES2928401T3 (enExample)
IL (2) IL296875A (enExample)
MX (3) MX2017008721A (enExample)
NZ (1) NZ733010A (enExample)
TW (2) TWI821755B (enExample)
WO (1) WO2016109400A2 (enExample)
ZA (1) ZA201704426B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102618877B1 (ko) 2014-12-31 2023-12-28 랜티우스 메디컬 이메징, 인크. 지질-캡슐화된 기체 마이크로스피어 조성물 및 관련 방법
EP3452108A4 (en) * 2016-05-04 2019-12-25 Lantheus Medical Imaging, Inc. METHOD AND DEVICES FOR THE PRODUCTION OF ULTRASONIC CONTRASTING AGENTS
US9789210B1 (en) 2016-07-06 2017-10-17 Lantheus Medical Imaging, Inc. Methods for making ultrasound contrast agents

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