IL269970B - Polynucleotides that modulate the immune system, their antibody binding, and methods of using them - Google Patents

Polynucleotides that modulate the immune system, their antibody binding, and methods of using them

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Publication number
IL269970B
IL269970B IL269970A IL26997019A IL269970B IL 269970 B IL269970 B IL 269970B IL 269970 A IL269970 A IL 269970A IL 26997019 A IL26997019 A IL 26997019A IL 269970 B IL269970 B IL 269970B
Authority
IL
Israel
Prior art keywords
cpg
oligonucleotide
group
independently
optionally substituted
Prior art date
Application number
IL269970A
Other languages
English (en)
Hebrew (he)
Other versions
IL269970A (https=
Inventor
Sukumar Sakamuri
Curt W Bradshaw
Son Lam
Joseph Stock
Edward Hyungsuk Ha
Laxman Eltepu
Dingguo Liu
Bin Liu
Iacono Giuseppe Dello
Bryan R Meade
Ayman Kabakibi
Original Assignee
Tallac Therapeutics Inc
Sukumar Sakamuri
Curt W Bradshaw
Son Lam
Joseph Stock
Edward Hyungsuk Ha
Laxman Eltepu
Dingguo Liu
Bin Liu
Iacono Giuseppe Dello
Bryan R Meade
Ayman Kabakibi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tallac Therapeutics Inc, Sukumar Sakamuri, Curt W Bradshaw, Son Lam, Joseph Stock, Edward Hyungsuk Ha, Laxman Eltepu, Dingguo Liu, Bin Liu, Iacono Giuseppe Dello, Bryan R Meade, Ayman Kabakibi filed Critical Tallac Therapeutics Inc
Publication of IL269970A publication Critical patent/IL269970A/he
Publication of IL269970B publication Critical patent/IL269970B/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7125—Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
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