IL226398B2 - Pharmaceutical formulations containing corticosteroids for administration on the skin - Google Patents
Pharmaceutical formulations containing corticosteroids for administration on the skinInfo
- Publication number
- IL226398B2 IL226398B2 IL226398A IL22639813A IL226398B2 IL 226398 B2 IL226398 B2 IL 226398B2 IL 226398 A IL226398 A IL 226398A IL 22639813 A IL22639813 A IL 22639813A IL 226398 B2 IL226398 B2 IL 226398B2
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical formulations
- topical administration
- formulations containing
- containing corticosteroids
- corticosteroids
- Prior art date
Links
- 239000003246 corticosteroid Substances 0.000 title 1
- 229960001334 corticosteroids Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 238000011200 topical administration Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45833910P | 2010-11-22 | 2010-11-22 | |
| PCT/US2011/059861 WO2012087443A1 (en) | 2010-11-22 | 2011-11-09 | Pharmaceutical formulations containing corticosteroids for topical administration |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL226398B IL226398B (en) | 2020-03-31 |
| IL226398B2 true IL226398B2 (en) | 2023-09-01 |
Family
ID=46064916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL226398A IL226398B2 (en) | 2010-11-22 | 2013-05-16 | Pharmaceutical formulations containing corticosteroids for administration on the skin |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US8809307B2 (enExample) |
| EP (2) | EP4233838A3 (enExample) |
| JP (1) | JP6111007B2 (enExample) |
| KR (2) | KR20140043044A (enExample) |
| CN (1) | CN103228281B (enExample) |
| AU (1) | AU2011345240B2 (enExample) |
| BR (1) | BR112013012476B1 (enExample) |
| CA (2) | CA2817524C (enExample) |
| ES (1) | ES2935814T3 (enExample) |
| HR (1) | HRP20230032T1 (enExample) |
| HU (1) | HUE061270T2 (enExample) |
| IL (1) | IL226398B2 (enExample) |
| LT (1) | LT2643002T (enExample) |
| MX (1) | MX346961B (enExample) |
| NZ (1) | NZ610659A (enExample) |
| PL (1) | PL2643002T3 (enExample) |
| PT (1) | PT2643002T (enExample) |
| RU (1) | RU2568598C2 (enExample) |
| SI (1) | SI2643002T1 (enExample) |
| WO (1) | WO2012087443A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11957753B2 (en) | 2010-11-22 | 2024-04-16 | Bausch Health Ireland Limited | Pharmaceutical formulations containing corticosteroids for topical administration |
| US8809307B2 (en) | 2010-11-22 | 2014-08-19 | Dow Pharmaceutical Sciences, Inc. | Pharmaceutical formulations containing corticosteroids for topical administration |
| CN103705440B (zh) * | 2012-10-08 | 2017-05-10 | 天津金耀集团有限公司 | 一种哈西奈德乳膏 |
| CN103705441B (zh) * | 2012-10-08 | 2017-06-23 | 天津金耀集团有限公司 | 一种丙酸倍氯米松乳膏 |
| US20140112959A1 (en) * | 2012-10-18 | 2014-04-24 | MiCal Pharmaceuticals LLC - H Series, a Series of MiCal Pharmaceuticals LLC, a Multi-Division Limite | Topical steroid composition and method |
| US10111956B2 (en) | 2013-06-03 | 2018-10-30 | Tolmar, Inc. | Corticosteroid compositions |
| CN104095805B (zh) * | 2014-01-02 | 2016-08-24 | 江苏知原药业有限公司 | 地奈德乳膏及其制备方法 |
| US20160184431A1 (en) * | 2014-03-11 | 2016-06-30 | Promius Pharma Llc | Topical compositions comprising a corticosteroid |
| KR102779108B1 (ko) * | 2015-06-18 | 2025-03-07 | 밸리언트 파마슈티컬즈 노오쓰 아메리카 엘엘씨 | 건선을 치료하기 위한 코르티코스테로이드 및 레티노이드를 포함하는 국소 조성물 |
| US20190133943A1 (en) * | 2015-06-18 | 2019-05-09 | Valeant Pharmaceuticals North America | Topical compositions and methods for treating skin diseases |
| CN106474052B (zh) * | 2016-12-16 | 2019-10-25 | 重庆华邦制药有限公司 | 二丙酸阿氯米松乳膏及其制备方法 |
| US11311482B2 (en) | 2017-05-12 | 2022-04-26 | Bausch Health Us, Llc | Topical compositions and methods for treating skin diseases |
| US10653656B2 (en) | 2018-04-05 | 2020-05-19 | Bausch Health Ireland Limited | Topical pharmaceutical compositions for treating skin conditions |
| CA3133174A1 (en) | 2019-03-14 | 2020-09-17 | Crescita Therapeutics Inc. | Rinse-off compositions and uses thereof for delivery of active agents |
| WO2021162796A1 (en) * | 2020-02-11 | 2021-08-19 | Taro Pharmaceutical Industries Ltd. | Compositions comprising desoximetasone and tazarotene |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5422361A (en) * | 1989-12-20 | 1995-06-06 | Schering Corporation | Stable cream and lotion bases for lipophilic drug compositions |
| WO2003055455A1 (en) * | 2001-12-21 | 2003-07-10 | Rhodia Inc. | Combined stable cationic and anionic surfactant compositions |
| US6656928B1 (en) * | 1999-09-02 | 2003-12-02 | Mccadden Michael E. | Composition for the topical treatment of rashes, dermatoses and lesions |
Family Cites Families (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LU75903A1 (enExample) | 1976-09-29 | 1978-05-16 | ||
| NL7105591A (en) | 1971-04-24 | 1972-10-26 | Topical antiphlogistic compsns - contng 3, 20-diketo-9 alpha, 11 beta-dichloro - 16 alpha, 17 alpha-dimethyl-21-hydroxy pregna-1,4- | |
| DE2655570A1 (de) | 1975-12-12 | 1977-06-16 | Ciba Geigy Ag | Neue polyhalogensteroide und verfahren zu ihrer herstellung |
| US4048310A (en) | 1976-02-24 | 1977-09-13 | E. R. Squibb & Sons, Inc. | Topical steroid formulation in form of lotion or cream |
| US4083974A (en) | 1977-03-07 | 1978-04-11 | The Upjohn Company | Topical steroidal anti-inflammatory preparations containing polyoxypropylene 15 stearyl ether |
| JPS5850964B2 (ja) * | 1978-03-07 | 1983-11-14 | 東興薬品工業株式会社 | ステロイド含有クリ−ム製剤およびその製造方法 |
| US4299828A (en) * | 1979-05-31 | 1981-11-10 | E. R. Squibb & Sons, Inc. | Corticosteroid stick formulations |
| US4233295A (en) | 1979-05-31 | 1980-11-11 | E. R. Squibb & Sons, Inc. | Corticosteroid formulations containing sebacate carrier |
| AU5794680A (en) | 1979-05-31 | 1980-12-04 | E.R. Squibb & Sons, Inc. | Corticosteroid stick formulations |
| CH649923A5 (de) | 1980-10-06 | 1985-06-28 | Glaxo Group Ltd | Topisch verabreichbare pharmazeutische zusammensetzungen, enthaltend anti-inflammatorische steroide. |
| JPS58225009A (ja) | 1982-06-23 | 1983-12-27 | Shionogi & Co Ltd | コルチコステロイド外用製剤 |
| DE3225848A1 (de) | 1982-07-07 | 1984-01-19 | Schering AG, 1000 Berlin und 4709 Bergkamen | Kortikoidhaltige zubereitung zur topischen applikation |
| US4552872A (en) | 1983-06-21 | 1985-11-12 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing corticosteroids |
| GB8401965D0 (en) | 1984-01-25 | 1984-02-29 | Beecham Group Plc | Composition |
| JPH0764734B2 (ja) * | 1986-03-17 | 1995-07-12 | 大正製薬株式会社 | 経皮投与製剤 |
| CA1303991C (en) | 1986-03-31 | 1992-06-23 | Chung H. Cheng | Composition and method for delivering a steroid active ingredient |
| JPS62238216A (ja) * | 1986-04-03 | 1987-10-19 | Otsuka Pharmaceut Factory Inc | ステロイドクリ−ム製剤 |
| US5019569A (en) | 1986-11-03 | 1991-05-28 | Ortho Pharmaceutical Corporation | Reversal of glucocorticoid-induced skin atrophy |
| JPH0676327B2 (ja) | 1987-04-14 | 1994-09-28 | 株式会社大塚製薬工場 | ステロイド軟膏製剤 |
| JPH0676328B2 (ja) * | 1987-04-14 | 1994-09-28 | 株式会社大塚製薬工場 | ステロイドクリ−ム製剤 |
| JPH07116026B2 (ja) | 1987-07-07 | 1995-12-13 | 株式会社資生堂 | ジクロフェナックナトリウム含有乳化外用剤 |
| KR0168436B1 (ko) | 1990-03-02 | 1999-01-15 | 후쿠하라 요시하루 | 비스테로이드계 소염진통제를 함유하는 수중유형 유화 조성물 |
| TW218849B (enExample) * | 1991-05-17 | 1994-01-11 | Bristol Myers Squibb Co | |
| US5326566A (en) | 1991-05-17 | 1994-07-05 | Bristol-Myers Squibb Company | Use of dibutyl adipate and isopropyl myristate in topical and transdermal products |
| WO1993009583A1 (en) * | 1991-10-29 | 1993-05-13 | Audio Authority Corporation | Apparatus and method for interconnecting electronic products |
| US6974807B1 (en) | 1997-02-20 | 2005-12-13 | Allergan, Inc. | Tazarotene and corticosteroid treatment for psoriasis |
| US5972920A (en) * | 1998-02-12 | 1999-10-26 | Dermalogix Partners, Inc. | Formulation containing a carrier, active ingredient, and surfactant for treating skin disorders |
| SE9800729L (sv) | 1998-03-06 | 1999-09-07 | Scotia Lipidteknik Ab | Ny topikal formulering I |
| US5990100A (en) * | 1998-03-24 | 1999-11-23 | Panda Pharmaceuticals, L.L.C. | Composition and method for treatment of psoriasis |
| GB9823036D0 (en) * | 1998-10-22 | 1998-12-16 | Glaxo Group Ltd | Fluticasone lotion having improved vasoconstrictor activity |
| WO2000040250A1 (fr) * | 1999-01-06 | 2000-07-13 | Taisho Pharmaceutical Co.,Ltd. | Lotion a base d'amelometasone |
| AU2877800A (en) | 1999-02-12 | 2000-08-29 | Susan Bershad | Short contact treatment of psoriasis with topical retinoids |
| US6271219B2 (en) | 1999-06-25 | 2001-08-07 | Rajaram Vaidyanathan | Topical formulations comprising skin penetration agents and the use thereof |
| US6479058B1 (en) | 1999-09-02 | 2002-11-12 | Mccadden Michael E. | Composition for the topical treatment of poison ivy and other forms of contact dermatitis |
| US6387383B1 (en) | 2000-08-03 | 2002-05-14 | Dow Pharmaceutical Sciences | Topical low-viscosity gel composition |
| US6579512B2 (en) * | 2001-06-15 | 2003-06-17 | Crutchfield, Iii Charles E. | Topical steroid spray |
| US6709663B2 (en) | 2001-08-31 | 2004-03-23 | Healthpoint, Ltd. | Multivesicular emulsion drug delivery systems |
| US6765001B2 (en) | 2001-12-21 | 2004-07-20 | Medicis Pharmaceutical Corporation | Compositions and methods for enhancing corticosteroid delivery |
| US9265725B2 (en) | 2002-10-25 | 2016-02-23 | Foamix Pharmaceuticals Ltd. | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof |
| US7544674B2 (en) | 2002-10-25 | 2009-06-09 | Galderma S.A. | Topical skin care composition |
| US20060018937A1 (en) | 2002-10-25 | 2006-01-26 | Foamix Ltd. | Steroid kit and foamable composition and uses thereof |
| US7820145B2 (en) | 2003-08-04 | 2010-10-26 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
| JP2004359585A (ja) | 2003-06-03 | 2004-12-24 | Medorekkusu:Kk | 被膜形成型の副腎皮質ステロイド薬含有外用製剤 |
| US20050101582A1 (en) | 2003-11-12 | 2005-05-12 | Allergan, Inc. | Compositions and methods for treating a posterior segment of an eye |
| US8741333B2 (en) | 2004-06-07 | 2014-06-03 | Nuvo Research Inc. | Compositions and methods for treating dermatitis or psoriasis |
| US8449867B2 (en) * | 2004-08-31 | 2013-05-28 | Stiefel Research Australia Pty Ltd | Microemulsion and sub-micron emulsion process and compositions |
| JPWO2006098353A1 (ja) | 2005-03-15 | 2008-08-28 | 協和醗酵工業株式会社 | 外用剤 |
| US20060239929A1 (en) | 2005-04-25 | 2006-10-26 | Dow Gordon J | Use of a clobetasol spray formulation to treat psoriasis |
| EP1957080A4 (en) | 2005-12-09 | 2013-10-09 | Fougera Pharmaceuticals Inc | TOPICAL GLUCOCORTICOSTEROID FORMULATIONS |
| CA2633464A1 (en) | 2005-12-14 | 2007-09-07 | Zars Pharma, Inc. | Compositions and methods for dermal delivery of drugs |
| EP2051697A2 (en) | 2006-07-05 | 2009-04-29 | Foamix Ltd. | Foamable vehicle comprising dicarboxylic acid or dicarboxylic acid ester and pharmaceutical compositions thereof |
| AU2007355106A1 (en) | 2006-11-29 | 2008-12-18 | Foamix Ltd. | Foamable waterless compositions with modulating agents |
| US20100323998A1 (en) * | 2007-08-06 | 2010-12-23 | Glenmark Pharmaceuticals Ltd. | Topical composition containing the combination of mupirocin and beclomethasone |
| MX2010002592A (es) | 2007-09-10 | 2010-03-30 | Glenmark Pharmaceuticals Ltd | Composicion farmaceutica topica para la combinacion de acido fusidico y corticoesteroides. |
| WO2009084020A2 (en) | 2007-10-18 | 2009-07-09 | Glenmark Pharmaceuticals Limited | Topical composition comprising halobetasol and salicylic acid |
| MX2010013562A (es) | 2008-06-26 | 2011-02-15 | Anterios Inc | Aplicacion dermica. |
| PE20110849A1 (es) * | 2008-10-03 | 2011-12-02 | Nexmed Holdings Inc | Composicion estabilizada para el tratamiento de la psoriasis |
| US20100249060A1 (en) * | 2009-02-23 | 2010-09-30 | Smith Jan G | Topical formulation of low level clobetasol propionate for treating disorders of the skin and mucous membranes |
| CA2753497C (en) | 2009-02-25 | 2016-07-05 | Stiefel Research Australia Pty Ltd | Topical foam composition |
| US20130310355A1 (en) | 2009-12-15 | 2013-11-21 | Young Pharmaceuticals, Inc. | Low toxicity topical active agent delivery system |
| WO2012051614A2 (en) | 2010-10-15 | 2012-04-19 | Kulesza John E | Delivery of hydrophobic bioactive agents |
| US11957753B2 (en) | 2010-11-22 | 2024-04-16 | Bausch Health Ireland Limited | Pharmaceutical formulations containing corticosteroids for topical administration |
| US8809307B2 (en) | 2010-11-22 | 2014-08-19 | Dow Pharmaceutical Sciences, Inc. | Pharmaceutical formulations containing corticosteroids for topical administration |
| US20140112959A1 (en) | 2012-10-18 | 2014-04-24 | MiCal Pharmaceuticals LLC - H Series, a Series of MiCal Pharmaceuticals LLC, a Multi-Division Limite | Topical steroid composition and method |
-
2011
- 2011-11-02 US US13/287,176 patent/US8809307B2/en active Active
- 2011-11-09 JP JP2013539894A patent/JP6111007B2/ja active Active
- 2011-11-09 EP EP22215648.1A patent/EP4233838A3/en active Pending
- 2011-11-09 KR KR1020137016271A patent/KR20140043044A/ko not_active Ceased
- 2011-11-09 KR KR1020187002956A patent/KR101967121B1/ko active Active
- 2011-11-09 PT PT118504190T patent/PT2643002T/pt unknown
- 2011-11-09 EP EP11850419.0A patent/EP2643002B1/en active Active
- 2011-11-09 SI SI201132078T patent/SI2643002T1/sl unknown
- 2011-11-09 RU RU2013128607/15A patent/RU2568598C2/ru active
- 2011-11-09 LT LTEPPCT/US2011/059861T patent/LT2643002T/lt unknown
- 2011-11-09 NZ NZ610659A patent/NZ610659A/en unknown
- 2011-11-09 HR HRP20230032TT patent/HRP20230032T1/hr unknown
- 2011-11-09 AU AU2011345240A patent/AU2011345240B2/en active Active
- 2011-11-09 ES ES11850419T patent/ES2935814T3/es active Active
- 2011-11-09 MX MX2013005764A patent/MX346961B/es active IP Right Grant
- 2011-11-09 CN CN201180056051.0A patent/CN103228281B/zh active Active
- 2011-11-09 PL PL11850419.0T patent/PL2643002T3/pl unknown
- 2011-11-09 CA CA2817524A patent/CA2817524C/en active Active
- 2011-11-09 WO PCT/US2011/059861 patent/WO2012087443A1/en not_active Ceased
- 2011-11-09 HU HUE11850419A patent/HUE061270T2/hu unknown
- 2011-11-09 CA CA3055328A patent/CA3055328C/en active Active
- 2011-11-09 BR BR112013012476-8A patent/BR112013012476B1/pt active IP Right Grant
-
2013
- 2013-05-16 IL IL226398A patent/IL226398B2/en unknown
-
2014
- 2014-07-24 US US14/340,367 patent/US11213587B2/en active Active
-
2017
- 2017-06-06 US US15/615,752 patent/US10478502B2/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5422361A (en) * | 1989-12-20 | 1995-06-06 | Schering Corporation | Stable cream and lotion bases for lipophilic drug compositions |
| US6656928B1 (en) * | 1999-09-02 | 2003-12-02 | Mccadden Michael E. | Composition for the topical treatment of rashes, dermatoses and lesions |
| WO2003055455A1 (en) * | 2001-12-21 | 2003-07-10 | Rhodia Inc. | Combined stable cationic and anionic surfactant compositions |
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