IL216742A0 - Bace inhibitors - Google Patents

Bace inhibitors

Info

Publication number
IL216742A0
IL216742A0 IL216742A IL21674211A IL216742A0 IL 216742 A0 IL216742 A0 IL 216742A0 IL 216742 A IL216742 A IL 216742A IL 21674211 A IL21674211 A IL 21674211A IL 216742 A0 IL216742 A0 IL 216742A0
Authority
IL
Israel
Prior art keywords
bace inhibitors
bace
inhibitors
Prior art date
Application number
IL216742A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42985394&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL216742(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL216742A0 publication Critical patent/IL216742A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
    • C07D279/08—1,3-Thiazines; Hydrogenated 1,3-thiazines condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
IL216742A 2009-07-09 2011-12-01 Bace inhibitors IL216742A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22424109P 2009-07-09 2009-07-09
PCT/US2010/041034 WO2011005738A1 (en) 2009-07-09 2010-07-06 Bace inhibitors

Publications (1)

Publication Number Publication Date
IL216742A0 true IL216742A0 (en) 2012-03-01

Family

ID=42985394

Family Applications (1)

Application Number Title Priority Date Filing Date
IL216742A IL216742A0 (en) 2009-07-09 2011-12-01 Bace inhibitors

Country Status (26)

Country Link
US (2) US8278441B2 (cg-RX-API-DMAC7.html)
EP (1) EP2451793B1 (cg-RX-API-DMAC7.html)
JP (1) JP5666578B2 (cg-RX-API-DMAC7.html)
KR (1) KR101362557B1 (cg-RX-API-DMAC7.html)
CN (1) CN102471296B (cg-RX-API-DMAC7.html)
AR (1) AR077277A1 (cg-RX-API-DMAC7.html)
AU (1) AU2010270691B8 (cg-RX-API-DMAC7.html)
BR (1) BR112012000525A2 (cg-RX-API-DMAC7.html)
CA (1) CA2764429C (cg-RX-API-DMAC7.html)
CL (1) CL2012000033A1 (cg-RX-API-DMAC7.html)
CO (1) CO6480979A2 (cg-RX-API-DMAC7.html)
CR (1) CR20120011A (cg-RX-API-DMAC7.html)
DO (1) DOP2012000004A (cg-RX-API-DMAC7.html)
EA (1) EA019892B1 (cg-RX-API-DMAC7.html)
EC (1) ECSP12011581A (cg-RX-API-DMAC7.html)
HN (1) HN2012000012A (cg-RX-API-DMAC7.html)
IL (1) IL216742A0 (cg-RX-API-DMAC7.html)
MA (1) MA33492B1 (cg-RX-API-DMAC7.html)
MX (1) MX2012000510A (cg-RX-API-DMAC7.html)
NZ (1) NZ596579A (cg-RX-API-DMAC7.html)
PE (1) PE20120632A1 (cg-RX-API-DMAC7.html)
SG (1) SG177594A1 (cg-RX-API-DMAC7.html)
TN (1) TN2011000673A1 (cg-RX-API-DMAC7.html)
TW (1) TWI405765B (cg-RX-API-DMAC7.html)
WO (1) WO2011005738A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201109385B (cg-RX-API-DMAC7.html)

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GB201100181D0 (en) * 2011-01-06 2011-02-23 Eisai Ltd Fused aminodihydrothiazine derivatives
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EA023824B1 (ru) 2011-03-09 2016-07-29 Янссен Фармацевтика Нв ПРОИЗВОДНЫЕ 3,4-ДИГИДРОПИРРОЛО[1,2-a]ПИРАЗИН-1-ИЛАМИНА, ПРИГОДНЫЕ В КАЧЕСТВЕ ИНГИБИТОРОВ БЕТА-СЕКРЕТАЗЫ (BACE)
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CN103608345A (zh) 2011-04-26 2014-02-26 盐野义制药株式会社 噁嗪衍生物和含有该噁嗪衍生物的bace1抑制剂
US8604024B2 (en) 2011-05-24 2013-12-10 Bristol-Myers Squibb Company Compounds for the reduction of beta-amyloid production
AR086539A1 (es) 2011-05-24 2014-01-08 Bristol Myers Squibb Co COMPUESTOS PARA LA REDUCCION DE LA PRODUCCION DE b-AMILOIDE
US8927535B2 (en) * 2011-07-06 2015-01-06 Hoffman-La Roche Inc. Cyclopropyl-fused-1,3-thiazepines as BACE1 and/or BACE2 inhibitors
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JP6043355B2 (ja) 2011-08-31 2016-12-14 ファイザー・インク ヘキサヒドロピラノ［３，４−ｄ］［１，３］チアジン−２−アミン化合物
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TWI675034B (zh) * 2016-05-20 2019-10-21 美商美國禮來大藥廠 四氫呋喃并<img align="absmiddle" height="18px" width="27px" file="d10999.TIF" alt="其他非圖式 ed10999.png" img-content="tif" orientation="portrait" inline="yes" giffile="ed10999.png"></img>化合物及其作為選擇性ＢＡＣＥ１抑制劑之用途
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AU2017378316B2 (en) 2016-12-15 2021-04-01 Amgen Inc. Cyclopropyl fused thiazine derivatives as beta-secretase inhibitors and methods of use
JP7148518B2 (ja) 2016-12-15 2022-10-05 アムジエン・インコーポレーテツド β－セクレターゼ阻害剤としての二環式チアジンおよびオキサジン誘導体ならびに使用方法
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MA33492B1 (fr) 2012-08-01
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CN102471296A (zh) 2012-05-23
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ZA201109385B (en) 2013-05-29
CA2764429C (en) 2014-11-18
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JP2012532874A (ja) 2012-12-20
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AU2010270691B8 (en) 2013-11-28
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AU2010270691A1 (en) 2011-12-22
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