IL213668A - Botulinum toxin for injection and their therapeutic and cosmetic uses - Google Patents

Botulinum toxin for injection and their therapeutic and cosmetic uses

Info

Publication number
IL213668A
IL213668A IL213668A IL21366811A IL213668A IL 213668 A IL213668 A IL 213668A IL 213668 A IL213668 A IL 213668A IL 21366811 A IL21366811 A IL 21366811A IL 213668 A IL213668 A IL 213668A
Authority
IL
Israel
Prior art keywords
therapeutic
botulinum toxin
cosmetic uses
toxin formulations
injectable botulinum
Prior art date
Application number
IL213668A
Other languages
English (en)
Hebrew (he)
Other versions
IL213668A0 (en
Original Assignee
Revance Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42285690&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL213668(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Revance Therapeutics Inc filed Critical Revance Therapeutics Inc
Publication of IL213668A0 publication Critical patent/IL213668A0/en
Publication of IL213668A publication Critical patent/IL213668A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/08Clostridium, e.g. Clostridium tetani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/06Anti-spasmodics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/16Emollients or protectives, e.g. against radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/91Injection
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Birds (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Toxicology (AREA)
  • Otolaryngology (AREA)
  • Psychology (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
IL213668A 2008-12-31 2011-06-20 Botulinum toxin for injection and their therapeutic and cosmetic uses IL213668A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14206308P 2008-12-31 2008-12-31
PCT/US2009/069576 WO2010078242A1 (en) 2008-12-31 2009-12-28 Injectable botulinum toxin formulations

Publications (2)

Publication Number Publication Date
IL213668A0 IL213668A0 (en) 2011-07-31
IL213668A true IL213668A (en) 2017-11-30

Family

ID=42285690

Family Applications (3)

Application Number Title Priority Date Filing Date
IL213668A IL213668A (en) 2008-12-31 2011-06-20 Botulinum toxin for injection and their therapeutic and cosmetic uses
IL254558A IL254558B (en) 2008-12-31 2017-09-18 Injectable botulinum toxin formulations
IL281675A IL281675A (en) 2008-12-31 2021-03-21 Injectable botulinum toxin formulations

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL254558A IL254558B (en) 2008-12-31 2017-09-18 Injectable botulinum toxin formulations
IL281675A IL281675A (en) 2008-12-31 2021-03-21 Injectable botulinum toxin formulations

Country Status (25)

Country Link
US (5) US9956435B2 (OSRAM)
EP (2) EP2379104B1 (OSRAM)
JP (6) JP5866202B2 (OSRAM)
KR (4) KR102005930B1 (OSRAM)
CN (2) CN102300584A (OSRAM)
AU (6) AU2009332947C1 (OSRAM)
BR (1) BRPI0923731B1 (OSRAM)
CA (1) CA2749757C (OSRAM)
CO (1) CO6400199A2 (OSRAM)
CY (1) CY1120137T1 (OSRAM)
DK (2) DK3332805T3 (OSRAM)
ES (2) ES2669020T3 (OSRAM)
HR (1) HRP20180739T1 (OSRAM)
HU (1) HUE037595T2 (OSRAM)
IL (3) IL213668A (OSRAM)
LT (1) LT2379104T (OSRAM)
MX (1) MX2011007059A (OSRAM)
NO (1) NO2379104T3 (OSRAM)
PL (1) PL2379104T3 (OSRAM)
PT (1) PT2379104T (OSRAM)
RU (1) RU2011125775A (OSRAM)
SG (3) SG10201405582YA (OSRAM)
SI (1) SI2379104T1 (OSRAM)
SM (1) SMT201800215T1 (OSRAM)
WO (1) WO2010078242A1 (OSRAM)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA06009897A (es) 2004-03-03 2008-02-07 Revance Therapeutics Inc Composiciones y metodos para el diagnostico topico y el transporte terapeutico.
US9211248B2 (en) 2004-03-03 2015-12-15 Revance Therapeutics, Inc. Compositions and methods for topical application and transdermal delivery of botulinum toxins
MX2007010673A (es) * 2005-03-03 2008-04-07 Revance Therapeutics Inc Composiciones y metodos para la aplicacion topica y el suministro transdermico de toxinas botulinicas.
US20080226551A1 (en) * 2006-12-29 2008-09-18 Revance Therapeutics, Inc. Transport Molecules Using Reverse Sequence HIV-TAT Polypeptides
PT2178549T (pt) * 2007-07-26 2016-12-20 Revance Therapeutics Inc Péptido antimicrobiano e suas composições
US7967795B1 (en) 2010-01-19 2011-06-28 Lamodel Ltd. Cartridge interface assembly with driving plunger
US9345836B2 (en) 2007-10-02 2016-05-24 Medimop Medical Projects Ltd. Disengagement resistant telescoping assembly and unidirectional method of assembly for such
US9656019B2 (en) 2007-10-02 2017-05-23 Medimop Medical Projects Ltd. Apparatuses for securing components of a drug delivery system during transport and methods of using same
BRPI0817907B8 (pt) 2007-10-02 2021-06-22 Lamodel Ltd aparelho para administrar uma substância a um indivíduo
US10420880B2 (en) 2007-10-02 2019-09-24 West Pharma. Services IL, Ltd. Key for securing components of a drug delivery system during assembly and/or transport and methods of using same
US8198034B2 (en) 2008-03-14 2012-06-12 Allergan, Inc. Immuno-based botulinum toxin serotype A activity assays
US12097357B2 (en) 2008-09-15 2024-09-24 West Pharma. Services IL, Ltd. Stabilized pen injector
US9393369B2 (en) 2008-09-15 2016-07-19 Medimop Medical Projects Ltd. Stabilized pen injector
NO2379104T3 (OSRAM) 2008-12-31 2018-07-28
KR101975051B1 (ko) * 2009-06-25 2019-05-03 레반스 테라퓨틱스, 아이엔씨. 알부민­불포함 보툴리눔 독소 제제
US10071198B2 (en) 2012-11-02 2018-09-11 West Pharma. Servicees IL, Ltd. Adhesive structure for medical device
US8157769B2 (en) 2009-09-15 2012-04-17 Medimop Medical Projects Ltd. Cartridge insertion assembly for drug delivery system
US10071196B2 (en) 2012-05-15 2018-09-11 West Pharma. Services IL, Ltd. Method for selectively powering a battery-operated drug-delivery device and device therefor
SMT201800487T1 (it) * 2009-10-21 2019-01-11 Revance Therapeutics Inc Metodi e sistemi per purificare neurotossina botulinica non complessata
WO2011063395A2 (en) * 2009-11-23 2011-05-26 The Johns Hopkins University Lateral flow device for diagnosing microbial infections
US10585098B2 (en) 2009-11-23 2020-03-10 The Johns Hopkins University Optimizing diagnostics for galactofuranose containing antigens
US8348898B2 (en) 2010-01-19 2013-01-08 Medimop Medical Projects Ltd. Automatic needle for drug pump
US9452261B2 (en) * 2010-05-10 2016-09-27 Medimop Medical Projects Ltd. Low volume accurate injector
KR101134146B1 (ko) * 2010-05-31 2012-04-19 메덱스젠 주식회사 국소 근마비 효과를 갖는 비확산형 보툴리눔 독소와 그의 정제방법
HUE035057T2 (en) * 2011-01-07 2018-05-02 Revance Therapeutics Inc Topical composition comprising botulinum toxin and a dye
USD702834S1 (en) 2011-03-22 2014-04-15 Medimop Medical Projects Ltd. Cartridge for use in injection device
US9072827B2 (en) 2012-03-26 2015-07-07 Medimop Medical Projects Ltd. Fail safe point protector for needle safety flap
US20140120077A1 (en) * 2012-10-28 2014-05-01 Revance Therapeutics, Inc. Compositions and Methods for Safe Treatment of Rhinitis
US9421323B2 (en) 2013-01-03 2016-08-23 Medimop Medical Projects Ltd. Door and doorstop for portable one use drug delivery apparatus
US9011164B2 (en) 2013-04-30 2015-04-21 Medimop Medical Projects Ltd. Clip contact for easy installation of printed circuit board PCB
RU2535115C1 (ru) 2013-05-15 2014-12-10 Бости Трейдинг Лтд Фармацевтический состав, содержащий нейротоксин ботулина
GB201312317D0 (en) * 2013-07-09 2013-08-21 Syntaxin Ltd Cationic neurotoxins
US9480731B2 (en) 2013-12-12 2016-11-01 Medy-Tox, Inc. Long lasting effect of new botulinum toxin formulations
US10107822B2 (en) 2013-12-16 2018-10-23 The Johns Hopkins University Interferon-gamma release assays for diagnosis of invasive fungal infections
ES2642916T3 (es) * 2014-06-06 2017-11-20 Galit KLEINER-FISMAN Toxina botulínica para su uso en el tratamiento de la paratonia
US11484580B2 (en) 2014-07-18 2022-11-01 Revance Therapeutics, Inc. Topical ocular preparation of botulinum toxin for use in ocular surface disease
EP3747427A1 (en) * 2014-07-31 2020-12-09 Allergan, Inc. Formulations of biologics for intravesical instillation
US10864231B2 (en) * 2014-09-02 2020-12-15 American Silver, Llc Botulinum toxin and colloidal silver particles
EP3236939B2 (en) * 2014-12-23 2024-08-28 Merz Pharma GmbH & Co. KGaA Botulinum toxin prefilled container
US10293120B2 (en) 2015-04-10 2019-05-21 West Pharma. Services IL, Ltd. Redundant injection device status indication
KR102099326B1 (ko) * 2015-04-13 2020-04-09 주식회사 엘지생활건강 폴리페놀 전달용 용해성 마이크로니들
HK1247575A1 (zh) 2015-04-13 2018-09-28 株式会社Lg生活健康 含有调节神经递质释放的成分的可溶性微针
US10149943B2 (en) 2015-05-29 2018-12-11 West Pharma. Services IL, Ltd. Linear rotation stabilizer for a telescoping syringe stopper driverdriving assembly
EP3302652B1 (en) 2015-06-04 2023-09-06 Medimop Medical Projects Ltd. Cartridge insertion for drug delivery device
US10576207B2 (en) 2015-10-09 2020-03-03 West Pharma. Services IL, Ltd. Angled syringe patch injector
US9987432B2 (en) 2015-09-22 2018-06-05 West Pharma. Services IL, Ltd. Rotation resistant friction adapter for plunger driver of drug delivery device
CN112972833B (zh) 2015-10-09 2024-01-09 西医药服务以色列分公司 注射器针帽脱离器
WO2017075468A1 (en) 2015-10-29 2017-05-04 Revance Therapeutics, Inc. Injectable botulinum toxin formulations and methods of use thereof having long duration of therapeutic or cosmetic effect
CN111544704B (zh) 2016-01-21 2022-06-03 西医药服务以色列有限公司 自动注射器中的力牵制
WO2017127215A1 (en) 2016-01-21 2017-07-27 Medimop Medical Projects Ltd. Needle insertion and retraction mechanism
JP6885960B2 (ja) 2016-01-21 2021-06-16 ウェスト ファーマ サービシーズ イスラエル リミテッド 視覚的インジケータを有する薬剤デリバリデバイス
US20170209553A1 (en) * 2016-01-22 2017-07-27 Transderm, Inc. Delivery of botulinum with microneedle arrays
US11389597B2 (en) 2016-03-16 2022-07-19 West Pharma. Services IL, Ltd. Staged telescopic screw assembly having different visual indicators
US11103652B2 (en) 2016-06-02 2021-08-31 West Pharma. Services IL, Ltd. Three position needle retraction
US11730892B2 (en) 2016-08-01 2023-08-22 West Pharma. Services IL, Ltd. Partial door closure prevention spring
JP6869327B2 (ja) 2016-08-01 2021-05-12 ウェスト ファーマ サービシーズ イスラエル リミテッド 回転防止カートリッジ
BR112019004935A2 (pt) 2016-09-13 2019-06-04 Allergan Inc composições de toxina clostridial não proteíca estabilizada
MX2019005833A (es) * 2016-11-21 2019-10-30 Eirion Therapeutics Inc Administracion transdermica de agentes grandes.
AU2018222745B2 (en) * 2017-02-17 2021-02-18 Allergan, Inc. Microneedle array with active ingredient
JP7604222B2 (ja) * 2017-03-22 2024-12-23 ボンチ インコーポレイテッド 治療用のボツリヌス神経毒素
CN107185042B (zh) * 2017-04-29 2020-09-01 杭州维多利亚医疗美容医院有限公司 一种美容注射剂及其制备方法
MX2019013716A (es) * 2017-05-18 2020-10-12 Revance Therapeutics Inc Métodos de tratamiento para la distonía cervical.
EP3630226B1 (en) 2017-05-30 2025-10-22 West Pharma. Services Il, Ltd. Modular drive train for wearable injector
EP3675900A4 (en) * 2017-08-28 2021-05-05 Revance Therapeutics, Inc. Transmucosal botulinum toxin compositions, kits, and methods for treating bladder disorders
KR20190038292A (ko) * 2017-09-29 2019-04-08 한국프라임제약주식회사 효능 지속시간이 연장된 보툴리눔 독소 조성물
EP3703738A4 (en) * 2017-11-03 2021-09-08 ReVance Therapeutics, Inc. BOTULINIC TOXIN FORMULATIONS AND METHODS OF USE THEREOF IN PLANTARY FASCIITIS, WITH EXTENDED DURATION OF EFFECT
US20200384090A1 (en) * 2017-12-04 2020-12-10 Revance Therapeutics, Inc. Injectable botulinum toxin formulations and methods of use thereof having high response rate and long effect duration
CN114470420B (zh) 2017-12-22 2024-08-27 西氏医药包装(以色列)有限公司 适用于不同尺寸的药筒的注射器
KR102088104B1 (ko) 2018-06-29 2020-03-11 호서대학교 산학협력단 개망초 꽃 에센셜 오일을 포함하는 신경 근육 관련 질환 예방 및 치료용 조성물
MX2021006102A (es) 2018-12-03 2021-09-21 Eirion Therapeutics Inc Suministro mejorado de agentes grandes.
EP3969038A1 (en) 2019-05-14 2022-03-23 Eirion Therapeutics, Inc. Delaying peak effect and/or extending duration of response
MY205101A (en) 2020-03-31 2024-10-02 Obi Pharma Inc Botulinum toxin type a complex, and formulation thereof and usage method therefor
US20230165946A1 (en) * 2020-04-08 2023-06-01 Medytox Inc. Botulinum toxin pre-filled injectable formulation that facilitates discharge rate control and is stable
WO2021251789A1 (ko) 2020-06-12 2021-12-16 (주)케어젠 펜타펩타이드를 유효성분으로 포함하는 조성물
KR20220114183A (ko) * 2021-02-08 2022-08-17 주식회사 대웅 장기 저장이 가능한 보툴리눔 독소 동결건조 제형 조성물
JP2025519507A (ja) * 2022-06-10 2025-06-26 メディトックス インク. ボツリヌス毒素安定化組成物、それを含むボツリヌス毒素製剤及びそれに用いるためのポリペプチド
KR102714765B1 (ko) * 2023-05-04 2024-10-11 주식회사 파마리서치바이오 Dna 단편 혼합물 및 보툴리눔 독소를 포함하는 보툴리눔 독소의 생체 내 지속성이 증가된 지속성 제제
WO2025064729A1 (en) 2023-09-19 2025-03-27 Revance Therapeutics, Inc. Treatment with botulinum toxin in patients in need of a rapid onset cosmetic effect and smoother skin appearance
WO2025229073A1 (en) * 2024-05-01 2025-11-06 Fastox Pharma Sa Aqueous compositions of dantrolene

Family Cites Families (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5804604A (en) 1989-12-21 1998-09-08 Biogen, Inc. Tat-derived transport polypeptides and fusion proteins
US5877278A (en) 1992-09-24 1999-03-02 Chiron Corporation Synthesis of N-substituted oligomers
HU220194B (hu) 1992-10-02 2001-11-28 Genetics Institute Inc. Koagulációs faktor VIII-at tartalmazó készítmény és eljárás előállítására
EP1790352B1 (en) 1993-12-28 2008-07-09 Allergan, Inc. Use of botulinum toxin for the manufacture of a medicament for reducing low back pain
US5512547A (en) 1994-10-13 1996-04-30 Wisconsin Alumni Research Foundation Pharmaceutical composition of botulinum neurotoxin and method of preparation
US5756468A (en) 1994-10-13 1998-05-26 Wisconsin Alumni Research Foundation Pharmaceutical compositions of botulinum toxin or botulinum neurotoxin and methods of preparation
GB9508204D0 (en) 1995-04-21 1995-06-07 Speywood Lab Ltd A novel agent able to modify peripheral afferent function
US6444209B1 (en) 1996-10-28 2002-09-03 Wisconsin Alumni Research Foundation Hybrid botulinal neurotoxins
US20030095927A1 (en) 1997-10-01 2003-05-22 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating muscular and skeletal disorders
WO1999037326A1 (en) 1998-01-26 1999-07-29 University Of Massachusetts Biologically active hemagglutinin from type a clostridium botulinum and methods of use
TW574036B (en) 1998-09-11 2004-02-01 Elan Pharm Inc Stable liquid compositions of botulinum toxin
US6358917B1 (en) 1999-08-24 2002-03-19 Jean D. A. Carruthers Cosmetic use of botulinum toxin for treatment of downturned mouth
US6544548B1 (en) 1999-09-13 2003-04-08 Keraplast Technologies, Ltd. Keratin-based powders and hydrogel for pharmaceutical applications
US6844324B1 (en) 1999-11-12 2005-01-18 Massachusetts Institute Of Technology Modular peptide mediated intracellular delivery system and uses therefore
IL149778A0 (en) 1999-11-22 2002-11-10 Universal Preservation Technologies Inc Preservation of sensitive biological material
US7780967B2 (en) 2000-02-08 2010-08-24 Allergan, Inc. Reduced toxicity Clostridial toxin pharmaceutical compositions
NZ520201A (en) 2000-02-08 2004-04-30 Allergan Inc Botulinum toxin pharmaceutical compositions comprising a polysaccharide
US20030118598A1 (en) 2000-02-08 2003-06-26 Allergan, Inc. Clostridial toxin pharmaceutical compositions
US6670322B2 (en) 2000-06-01 2003-12-30 Wisconsin Alumni Research Foundation Method of targeting pharmaceuticals to motor neurons
US6306423B1 (en) 2000-06-02 2001-10-23 Allergan Sales, Inc. Neurotoxin implant
US20040033241A1 (en) 2000-06-02 2004-02-19 Allergan, Inc. Controlled release botulinum toxin system
US20030215412A1 (en) * 2000-07-21 2003-11-20 Essentia Biosystems, Inc. Induction of hair growth with vascular endothelial growth factor
US20040220100A1 (en) 2000-07-21 2004-11-04 Essentia Biosystems, Inc. Multi-component biological transport systems
ES2617692T3 (es) 2000-07-21 2017-06-19 Revance Therapeutics, Inc. Sistemas de transporte de agentes biológicos de múltiples componentes
US6787517B1 (en) 2000-12-29 2004-09-07 Allergan, Inc. Agent and methods for treating pain
US20020197278A1 (en) 2001-06-21 2002-12-26 Surromed, Inc. Covalent coupling of botulinum toxin with polyethylene glycol
KR20110091822A (ko) 2002-02-14 2011-08-12 추가이 세이야쿠 가부시키가이샤 항체함유 용액제제
US7691394B2 (en) 2002-05-28 2010-04-06 Botulinum Toxin Research Associates, Inc. High-potency botulinum toxin formulations
WO2003101483A1 (en) 2002-05-31 2003-12-11 Solux Corporation Pharmaceutical preparation of botulinum neurotoxin, methods of synthesis and methods of clinical use
US20040009180A1 (en) 2002-07-11 2004-01-15 Allergan, Inc. Transdermal botulinum toxin compositions
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US8119109B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
RU2206337C1 (ru) 2002-10-29 2003-06-20 Общество с ограниченной ответственностью "Токсины и сопутствующие продукты" Лекарственный препарат для лечения мышечных дистоний и способ его получения
US20040086532A1 (en) 2002-11-05 2004-05-06 Allergan, Inc., Botulinum toxin formulations for oral administration
DE10333317A1 (de) 2003-07-22 2005-02-17 Biotecon Therapeutics Gmbh Formulierung für Proteinarzneimittel ohne Zusatz von humanem Serumalbumin (HSA)
US20060210614A1 (en) * 2003-12-26 2006-09-21 Nastech Pharmaceutical Company Inc. Method of treatment of a metabolic disease using intranasal administration of exendin peptide
US20100266638A1 (en) 2004-02-26 2010-10-21 Allergan, Inc. Headache treatment method
US9211248B2 (en) 2004-03-03 2015-12-15 Revance Therapeutics, Inc. Compositions and methods for topical application and transdermal delivery of botulinum toxins
EP2656859B1 (en) 2004-03-03 2015-10-21 ReVance Therapeutics, Inc. Topical application and transdermal delivery of botulinum toxins
MXPA06009897A (es) * 2004-03-03 2008-02-07 Revance Therapeutics Inc Composiciones y metodos para el diagnostico topico y el transporte terapeutico.
GB2416122A (en) 2004-07-12 2006-01-18 Ipsen Ltd Botulinum neurotoxin composition
AU2005274822B2 (en) 2004-07-26 2008-10-30 Merz Pharma Gmbh & Co. Kgaa Therapeutic composition with a botulinum neurotoxin
US20070196364A1 (en) 2004-07-27 2007-08-23 Human Genome Sciences, Inc. Pharmaceutical Formulation and Process
US20080102090A1 (en) 2004-08-04 2008-05-01 Naveed Panjwani Pharmaceutical Compositon Containing Botulinum Neurotoxin A2
PL2813239T3 (pl) 2004-08-04 2017-11-30 Ipsen Biopharm Limited Kompozycja farmaceutyczna zawierająca neurotoksynę botulinową A2
GB2419526A (en) 2004-10-28 2006-05-03 Ipsen Ltd Pharmaceutical composition containing botulinum neurotoxin
US7727537B2 (en) 2005-02-14 2010-06-01 Dpm Therapeutics Corp. Stabilized compositions for topical administration and methods of making same
US7838011B2 (en) 2005-02-14 2010-11-23 Pankaj Modi Stabilized protein compositions for topical administration and methods of making same
EP1856139B1 (en) 2005-03-03 2011-04-27 Revance Therapeutics, Inc. Compositions and methods for topical application and transdermal delivery of an oligopeptide
MXPA06009854A (es) * 2005-03-03 2007-03-29 Allergan Inc Sistema libre de productos de origen animal y proceso para purificar una toxina botulinica.
MX2007010673A (es) 2005-03-03 2008-04-07 Revance Therapeutics Inc Composiciones y metodos para la aplicacion topica y el suministro transdermico de toxinas botulinicas.
CN101228187A (zh) * 2005-03-25 2008-07-23 特拉维夫大学拉莫特有限公司 针对突变p53的共同表位的人合成单链抗体及其用途
US8323666B2 (en) 2005-08-01 2012-12-04 Allergan, Inc. Botulinum toxin compositions
US8137677B2 (en) 2005-10-06 2012-03-20 Allergan, Inc. Non-protein stabilized clostridial toxin pharmaceutical compositions
BRPI0618753A2 (pt) 2005-11-17 2011-09-13 Revance Therapeutics Inc composição para liberação transdérmica de toxina botulìnica e método de administração
US9486408B2 (en) 2005-12-01 2016-11-08 University Of Massachusetts Lowell Botulinum nanoemulsions
AU2007234612B2 (en) 2006-12-14 2013-06-27 Johnson & Johnson Regenerative Therapeutics, Llc Protein stabilization formulations
FR2910327B1 (fr) 2006-12-22 2013-04-26 Scras Utilisation d'au moins une neurotoxine botulique pour traiter la douleur induite par les traitements therapeutiques du virus du sida.
WO2008082889A2 (en) * 2006-12-29 2008-07-10 Revance Therapeutics, Inc. Compositions and methods of topical application and transdermal delivery of botulinum toxins stabilized with polypeptide fragments derived from hiv-tat
BRPI0812245A2 (pt) 2007-06-01 2014-10-21 Merz Pharma Gmbh & Co Kgaa Método para provisão de um relaxante muscular termoestável com base no componente neurotóxico da toxina botulínica na forma sólida
PT2178549T (pt) * 2007-07-26 2016-12-20 Revance Therapeutics Inc Péptido antimicrobiano e suas composições
WO2009056651A1 (en) 2007-11-02 2009-05-07 Cytos Biotechnology Ag Angiotensin-carrier formulation
US9107815B2 (en) 2008-02-22 2015-08-18 Allergan, Inc. Sustained release poloxamer containing pharmaceutical compositions
KR20090120222A (ko) 2008-05-19 2009-11-24 (주)메디톡스 식물 유래 성분 함유 배지 및 가요성 폐쇄 용기를 이용하여클로스트리디움 보툴리눔 독소를 생산하는 방법
TW201023928A (en) * 2008-11-12 2010-07-01 Kythera Biopharmaceuticals Inc Systems and methods for delivery of biologically active agents
EP3067049A1 (en) 2008-12-10 2016-09-14 Allergan, Inc. Clostridial toxin pharmaceutical compositions
NO2379104T3 (OSRAM) 2008-12-31 2018-07-28
EP2248518B1 (en) 2009-04-17 2013-01-16 Merz Pharma GmbH & Co. KGaA Formulation for stabilizing proteins, peptides or mixtures thereof.
KR101975051B1 (ko) 2009-06-25 2019-05-03 레반스 테라퓨틱스, 아이엔씨. 알부민­불포함 보툴리눔 독소 제제
SMT201800487T1 (it) 2009-10-21 2019-01-11 Revance Therapeutics Inc Metodi e sistemi per purificare neurotossina botulinica non complessata
CA2774826A1 (en) 2009-10-30 2011-05-05 Revance Therapeutics, Inc. Device and method for topical application of therapeutic or cosmetic compositions
CA2814054A1 (en) 2010-10-12 2012-04-19 Merz Pharma Gmbh & Co. Kgaa Formulation suitable for stabilizing proteins, which is free of mammalian excipients
HUE035057T2 (en) 2011-01-07 2018-05-02 Revance Therapeutics Inc Topical composition comprising botulinum toxin and a dye
MX355771B (es) 2011-03-31 2018-04-30 Medy Tox Inc Preparacion liofilizada de toxinas de botulismo.
WO2013130535A1 (en) 2012-02-27 2013-09-06 Newgen Biopharma Corporation Topical delivery of hormonal and non hormonal nano formulations, methods of making and using the same
EP3236939B2 (en) 2014-12-23 2024-08-28 Merz Pharma GmbH & Co. KGaA Botulinum toxin prefilled container
HUE052023T2 (hu) 2016-05-27 2021-04-28 Ipsen Biopharm Ltd Triptofánnal vagy tirozinnal stabilizált folyékony neurotoxin készítmény

Also Published As

Publication number Publication date
CA2749757A1 (en) 2010-07-08
BRPI0923731B1 (pt) 2024-02-06
AU2018253620A1 (en) 2018-11-22
KR20170077292A (ko) 2017-07-05
LT2379104T (lt) 2018-04-10
US20110268765A1 (en) 2011-11-03
HRP20180739T1 (hr) 2018-06-29
EP2379104A4 (en) 2013-11-27
JP2017178954A (ja) 2017-10-05
DK3332805T3 (da) 2022-05-16
JP2015134784A (ja) 2015-07-27
AU2009332947B2 (en) 2016-07-07
AU2023229550A1 (en) 2023-11-23
JP5866202B2 (ja) 2016-02-17
JP6559849B2 (ja) 2019-08-14
AU2016238949B2 (en) 2018-07-26
JP6145465B2 (ja) 2017-06-14
DK2379104T3 (en) 2018-04-30
US20200215357A1 (en) 2020-07-09
IL254558A0 (en) 2017-11-30
AU2021200561A1 (en) 2021-02-25
IL281675A (en) 2021-05-31
AU2016238949A1 (en) 2016-10-27
EP3332805A1 (en) 2018-06-13
US20180214717A1 (en) 2018-08-02
JP2022028770A (ja) 2022-02-16
BRPI0923731A2 (pt) 2016-01-19
EP2379104A1 (en) 2011-10-26
AU2021200561B2 (en) 2023-06-15
KR20200131348A (ko) 2020-11-23
IL254558B (en) 2021-04-29
US20240058628A1 (en) 2024-02-22
CO6400199A2 (es) 2012-03-15
WO2010078242A1 (en) 2010-07-08
EP2379104B1 (en) 2018-02-28
KR102005930B1 (ko) 2019-07-31
RU2011125775A (ru) 2013-02-10
JP2018184460A (ja) 2018-11-22
PL2379104T3 (pl) 2018-07-31
US11471708B2 (en) 2022-10-18
SI2379104T1 (en) 2018-05-31
SG10202100698QA (en) 2021-02-25
KR20110117667A (ko) 2011-10-27
KR101753242B1 (ko) 2017-07-20
KR102363878B1 (ko) 2022-02-16
AU2023229550B2 (en) 2025-09-11
NO2379104T3 (OSRAM) 2018-07-28
JP2012514003A (ja) 2012-06-21
KR102179926B1 (ko) 2020-11-17
CA2749757C (en) 2024-03-26
JP2019194251A (ja) 2019-11-07
ES2908616T3 (es) 2022-05-03
CY1120137T1 (el) 2018-12-12
AU2025275321A1 (en) 2026-01-15
IL213668A0 (en) 2011-07-31
EP3332805B1 (en) 2022-02-23
SG10201405582YA (en) 2014-10-30
CN107343859A (zh) 2017-11-14
SG172812A1 (en) 2011-08-29
AU2016238949C1 (en) 2018-11-01
ES2669020T3 (es) 2018-05-23
PT2379104T (pt) 2018-03-26
AU2009332947C1 (en) 2019-01-03
HUE037595T2 (hu) 2018-09-28
HK1256878A1 (en) 2019-10-04
JP6976997B2 (ja) 2021-12-08
AU2018253620B2 (en) 2020-10-29
MX2011007059A (es) 2011-09-15
US9956435B2 (en) 2018-05-01
US20100168023A1 (en) 2010-07-01
SMT201800215T1 (it) 2018-05-02
CN102300584A (zh) 2011-12-28
KR20190091376A (ko) 2019-08-05
AU2009332947A1 (en) 2011-07-07

Similar Documents

Publication Publication Date Title
IL213668A (en) Botulinum toxin for injection and their therapeutic and cosmetic uses
IL268980A (en) Botulinum toxin formulations without albumin
IL275854A (en) Pharmaceutical composition and its administration
PL2510072T3 (pl) Terapeutyczne i kosmetyczne kompozycje elektroluminescencyjne
ZA201104497B (en) Peptide therapeutic conjugates and uses thereof
SG10201608068SA (en) Compositions And Methods For Skin Care
EP2370472A4 (en) LEPTIN AND LEPTIN ANALOGUE CONJUGATES AND ITS USES
EP2254546A4 (en) TOPICAL COMPOSITIONS AND METHODS FOR LAUNDERING THE SKIN
LT2606874T (lt) Naujos kosmetinės ir/arba farmacinės kompozicijos ir jų panaudojimas
GB0817938D0 (en) Cosmetic formulations
ZA201201727B (en) Indenone derivative and pharmaceutical composition comprising same
EP2268281A4 (en) THIENOPYRROLES AND PYRROLOTHIAZOLES AS NEW THERAPEUTIC AGENTS
GB201103265D0 (en) Cosmetic or dermatological composition comprising the combination of honey and a peptide
FR2926020B1 (fr) Composition cosmetique et/ou dermatologique
GB2460181B (en) Depsipeptides and their therapeutic use
GB2460178B (en) Depsipeptides and their therapeutic use
IL209220A0 (en) Plant extract and its therapeutic use
EP2345404A4 (en) COSMETICS AND COSMETIC PRODUCT IN THE FORM OF A PEN
PL2236145T3 (pl) Kompozycja farmaceutyczna i lek złożony
GB2460180B (en) Depsipeptides and their therapeutic use
GB0809324D0 (en) Depsipeptides and their therapeutic use
GB0809328D0 (en) Depsipeptides and their therapeutic use
GB0809326D0 (en) Depsipeptides and their therapeutic use
GB0809330D0 (en) Depsipeptides and their therapeutic use
GB0816943D0 (en) Hair treatment composition and methods

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed