IL192794A - Method to predict positive clinical outcome in patients diagnosed with colorectal cancer after surgical removal @ of cancer - Google Patents
Method to predict positive clinical outcome in patients diagnosed with colorectal cancer after surgical removal @ of cancerInfo
- Publication number
- IL192794A IL192794A IL192794A IL19279408A IL192794A IL 192794 A IL192794 A IL 192794A IL 192794 A IL192794 A IL 192794A IL 19279408 A IL19279408 A IL 19279408A IL 192794 A IL192794 A IL 192794A
- Authority
- IL
- Israel
- Prior art keywords
- cancer
- diagonsed
- human subject
- clinical outcome
- surgical resection
- Prior art date
Links
- 206010009944 Colon cancer Diseases 0.000 title 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000002271 resection Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57419—Specifically defined cancers of colon
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57446—Specifically defined cancers of stomach or intestine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75839206P | 2006-01-11 | 2006-01-11 | |
| US80027706P | 2006-05-12 | 2006-05-12 | |
| US81007706P | 2006-05-31 | 2006-05-31 | |
| PCT/US2007/000995 WO2007082099A2 (en) | 2006-01-11 | 2007-01-11 | Gene expression markers for colorectal cancer prognosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL192794A0 IL192794A0 (en) | 2009-02-11 |
| IL192794A true IL192794A (en) | 2013-07-31 |
Family
ID=38257063
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL192794A IL192794A (en) | 2006-01-11 | 2008-07-13 | Method to predict positive clinical outcome in patients diagnosed with colorectal cancer after surgical removal @ of cancer |
Country Status (14)
| Country | Link |
|---|---|
| US (10) | US7695913B2 (enExample) |
| EP (9) | EP2412824B1 (enExample) |
| JP (7) | JP5297202B2 (enExample) |
| KR (1) | KR20090003178A (enExample) |
| AU (1) | AU2007204826B2 (enExample) |
| BR (1) | BRPI0706511A2 (enExample) |
| CA (1) | CA2636984A1 (enExample) |
| DK (1) | DK1974058T3 (enExample) |
| ES (1) | ES2491222T3 (enExample) |
| IL (1) | IL192794A (enExample) |
| MX (1) | MX2008008973A (enExample) |
| NO (1) | NO20083461L (enExample) |
| NZ (7) | NZ593224A (enExample) |
| WO (1) | WO2007082099A2 (enExample) |
Families Citing this family (81)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2506066A1 (en) | 2002-11-15 | 2004-06-03 | Genomic Health, Inc. | Gene expression profiling of egfr positive cancer |
| CA2848463A1 (en) | 2004-04-09 | 2005-10-27 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
| KR20090003178A (ko) * | 2006-01-11 | 2009-01-09 | 게노믹 헬쓰, 인코포레이티드 | 직장결장암 예후에 대한 유전자 발현 마커 |
| US8768629B2 (en) * | 2009-02-11 | 2014-07-01 | Caris Mpi, Inc. | Molecular profiling of tumors |
| BRPI0711011A2 (pt) | 2006-05-18 | 2011-08-23 | Molecular Profiling Inst Inc | método para a determinação da intervenção médica para um estado de doença, método para a identificação de uma terapia de droga com capacidade de interação com um alvo molecular e sistema para a determinação da intervenção médica individualizada para um estado de doença |
| US20090076734A1 (en) | 2007-03-22 | 2009-03-19 | Torres-Roca Javier F | Gene Signature for the Prediction of Radiation Therapy Response |
| US20080234946A1 (en) * | 2007-03-22 | 2008-09-25 | University Of South Florida | Predictive radiosensitivity network model |
| WO2008117067A2 (en) | 2007-03-27 | 2008-10-02 | Carl Arne Krister Borrebaeck | Protein signature/markers for the detection of adenocarcinoma |
| US20090123920A1 (en) * | 2007-11-08 | 2009-05-14 | Maher Albitar | Jak2 mutations |
| ES2332167B1 (es) | 2007-12-04 | 2010-10-25 | Universidad Autonoma De Madrid | Empleo de trefoil factor-family 3 (tff3) en el pronostico de sujetos diagnosticados con cancer colorectal. |
| WO2009123634A1 (en) * | 2008-04-02 | 2009-10-08 | Regents Of The University Of California | Systems and methods for predicting response of biological samples |
| US8067178B2 (en) | 2008-03-14 | 2011-11-29 | Genomic Health, Inc. | Gene expression markers for prediction of patient response to chemotherapy |
| AU2009246398A1 (en) | 2008-05-14 | 2009-11-19 | Bristol-Myers Squibb Company | Predictors of patient response to treatment with EGF receptor inhibitors |
| US20100029748A1 (en) * | 2008-08-04 | 2010-02-04 | Sloan-Kettering Institute For Cancer Research | Metastasis Promoting Genes and Proteins |
| US10359425B2 (en) * | 2008-09-09 | 2019-07-23 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
| US20100221752A2 (en) * | 2008-10-06 | 2010-09-02 | Somalogic, Inc. | Ovarian Cancer Biomarkers and Uses Thereof |
| WO2010042228A2 (en) * | 2008-10-10 | 2010-04-15 | Cornell University | Methods for predicting disease outcome in patients with colon cancer |
| US20120041274A1 (en) | 2010-01-07 | 2012-02-16 | Myriad Genetics, Incorporated | Cancer biomarkers |
| US8765383B2 (en) | 2009-04-07 | 2014-07-01 | Genomic Health, Inc. | Methods of predicting cancer risk using gene expression in premalignant tissue |
| WO2010127322A1 (en) * | 2009-05-01 | 2010-11-04 | Genomic Health Inc. | Gene expression profile algorithm and test for likelihood of recurrence of colorectal cancer and response to chemotherapy |
| TWI513465B (zh) * | 2009-06-25 | 2015-12-21 | Regeneron Pharma | 以ｄｌｌ４拮抗劑與化學治療劑治療癌症之方法 |
| EP3812469A1 (en) | 2010-07-07 | 2021-04-28 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| MX355020B (es) | 2010-07-09 | 2018-04-02 | Somalogic Inc | Biomarcadores de cancer de pulmon y usos de los mismos. |
| MX338883B (es) | 2010-07-27 | 2016-05-04 | Genomic Health Inc | Metodo para usar expresion de gen para determinar el pronostico de cancer de prostata. |
| JP5931874B2 (ja) | 2010-08-13 | 2016-06-08 | ソマロジック・インコーポレーテッド | 膵癌バイオマーカーおよびその使用 |
| WO2012030840A2 (en) | 2010-08-30 | 2012-03-08 | Myriad Genetics, Inc. | Gene signatures for cancer diagnosis and prognosis |
| CN106978480A (zh) | 2010-09-15 | 2017-07-25 | 阿尔玛克诊断有限公司 | 用于癌症的分子诊断试验 |
| AU2012209074A1 (en) * | 2011-01-25 | 2013-07-11 | Almac Diagnostics Limited | Colon cancer gene expression signatures and methods of use |
| US10308980B2 (en) | 2011-11-04 | 2019-06-04 | Oslo Universitetssykehus Hf | Methods and biomarkers for analysis of colorectal cancer |
| AU2012344155A1 (en) | 2011-11-28 | 2014-07-03 | Fundacio Institut De Recerca Biomedica (Irb Barcelona) | Methods and kits for the prognosis of colorectal cancer |
| EP2794924B1 (en) | 2011-12-22 | 2019-02-06 | Baylor Research Institute | Identification of mirna signatures in human colorectal cancer |
| US9822417B2 (en) | 2012-01-09 | 2017-11-21 | Oslo Universitetssykehus Hf | Methods and biomarkers for analysis of colorectal cancer |
| SG11201404390WA (en) | 2012-01-31 | 2014-08-28 | Genomic Health Inc | Gene expression profile algorithm and test for determining prognosis of prostate cancer |
| WO2013150167A2 (es) | 2012-04-03 | 2013-10-10 | Servicio Andaluz De Salud | Modelo de expresión de microarn como indicador de supervivencia en pacientes de cancer colorrectal metastásico |
| US20160222457A1 (en) * | 2012-11-14 | 2016-08-04 | Mayo Foundation For Medical Education And Research | Methods and materials for identifying malignant skin lesions |
| WO2014078700A1 (en) | 2012-11-16 | 2014-05-22 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| ES2475366B1 (es) * | 2012-12-10 | 2015-05-05 | Fundación Imdea Alimentación | Métodos y kits para el pronóstico del cáncer colorrectal |
| WO2014159797A1 (en) | 2013-03-14 | 2014-10-02 | Abbott Molecular Inc. | Cell preparations and cell supports and their use in theranosis |
| WO2014191559A1 (en) * | 2013-05-30 | 2014-12-04 | Institució Catalana De Recerca I Estudis Avançats | Methods and kits for the prognosis of colorectal cancer |
| US10185809B1 (en) * | 2013-10-15 | 2019-01-22 | Iqvia Inc. | Patient projection methodology |
| GB201319878D0 (en) * | 2013-11-11 | 2013-12-25 | Immunovia Ab | Method, Array and use thereof |
| AU2015237229A1 (en) * | 2014-03-28 | 2016-11-10 | Applied Proteomics, Inc. | Protein biomarker profiles for detecting colorectal tumors |
| EP3143160B1 (en) | 2014-05-13 | 2019-11-06 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| US20170275700A1 (en) | 2014-08-14 | 2017-09-28 | Mayo Foundation For Medical Education And Research | Methods and materials for identifying metastatic malignant skin lesions and treating skin cancer |
| US10184154B2 (en) | 2014-09-26 | 2019-01-22 | Mayo Foundation For Medical Education And Research | Detecting cholangiocarcinoma |
| WO2016062892A1 (en) | 2014-10-24 | 2016-04-28 | Koninklijke Philips N.V. | Medical prognosis and prediction of treatment response using multiple cellular signaling pathway activities |
| AU2015334842B2 (en) | 2014-10-24 | 2022-02-17 | Koninklijke Philips N.V. | Medical prognosis and prediction of treatment response using multiple cellular signaling pathway activities |
| CN107077536B (zh) | 2014-10-24 | 2021-09-28 | 皇家飞利浦有限公司 | 使用靶基因表达的数学建模评价TGF-β细胞信号传导途径的活性 |
| DE112014007209T5 (de) | 2014-11-25 | 2017-08-03 | Mitsubishi Electric Corporation | Pneumatischer Antrieb |
| US20180148789A1 (en) * | 2014-12-01 | 2018-05-31 | University Of Southern California | Methods for treating and assessing tumor invasion and metastasis |
| CN107532124B (zh) | 2015-03-27 | 2022-08-09 | 精密科学公司 | 检测食管疾病 |
| EP3073268A1 (en) * | 2015-03-27 | 2016-09-28 | Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts | Biomarker panel for diagnosing cancer |
| GB2545361B (en) | 2015-04-10 | 2018-01-24 | Applied Proteomics Inc | Methods of assessing colorectal cancer status |
| CN108271422A (zh) * | 2015-06-25 | 2018-07-10 | 株式会社国际电气通信基础技术研究所 | 基于器官间串扰系统的预测装置及预测程序 |
| JP7028763B2 (ja) | 2015-08-14 | 2022-03-02 | コーニンクレッカ フィリップス エヌ ヴェ | 標的遺伝子発現の数学的モデリングを使用するＮＦｋＢ細胞シグナリング経路活性の評価 |
| JP6332780B2 (ja) | 2016-03-29 | 2018-05-30 | 株式会社国際電気通信基礎技術研究所 | 医薬組成物又は食品組成物、及び有効成分の体内での効果の評価方法 |
| JP6432962B2 (ja) | 2016-03-29 | 2018-12-05 | 株式会社国際電気通信基礎技術研究所 | 腎機能低下、慢性腎疾患及び腎不全からなる群から選択される少なくとも一種の疾患を予防、又は治療するための有効成分の候補物質のスクリーニング方法 |
| BR112018073014A2 (pt) | 2016-05-10 | 2019-02-19 | Mayo Foundation For Medical Education And Research | métodos e materiais para estadiamento e tratamento de câncer de pele |
| US11746381B2 (en) | 2017-03-10 | 2023-09-05 | Cancer Diagnostics Research Innvovations, LLC | Methods for diagnosing and treating gastric cancer using miRNA expression |
| WO2018224731A1 (en) * | 2017-06-05 | 2018-12-13 | Ls Cancerdiag Oy | A method for determining whether a subject is at risk to develop cancer and tools related thereto |
| EP3461915A1 (en) | 2017-10-02 | 2019-04-03 | Koninklijke Philips N.V. | Assessment of jak-stat1/2 cellular signaling pathway activity using mathematical modelling of target gene expression |
| EP3461916A1 (en) | 2017-10-02 | 2019-04-03 | Koninklijke Philips N.V. | Assessment of jak-stat3 cellular signaling pathway activity using mathematical modelling of target gene expression |
| EP3502279A1 (en) | 2017-12-20 | 2019-06-26 | Koninklijke Philips N.V. | Assessment of mapk-ap 1 cellular signaling pathway activity using mathematical modelling of target gene expression |
| JP7027179B2 (ja) * | 2018-01-24 | 2022-03-01 | キヤノン株式会社 | 給送回転体、シート給送装置及び画像形成装置 |
| WO2019173647A1 (en) | 2018-03-08 | 2019-09-12 | University Of Notre Dame Du Lac | Products for assessing colorectal cancer molecular subtype and risk of recurrence and for determining and adminstering treatment protocols based thereon |
| KR102007450B1 (ko) * | 2018-05-31 | 2019-08-05 | 한국과학기술연구원 | 대장암 치료제 발굴을 위한 신규 표적 치료 작용점의 스크리닝 방법 및 이를 이용하여 선별한 대장암 치료 예후 바이오마커 |
| CA3107401A1 (en) | 2018-07-25 | 2020-01-30 | Skylinedx B.V. | Gene signatures for predicting metastasis of melanoma and patient prognosis |
| US12370240B2 (en) | 2018-11-28 | 2025-07-29 | Genascence Corporation | Methods and compositions for treating osteoarthritis |
| WO2020123699A1 (en) * | 2018-12-11 | 2020-06-18 | The Trustees Of Columbia University In The City Of New York | Compounds and compositions that cause mycn and/or cmyc degradation and methods of use thereof |
| CN110257518B (zh) * | 2019-07-01 | 2022-08-02 | 复旦大学附属中山医院 | 一种用于预测转移性结直肠癌转化治疗疗效的基因集 |
| US12057959B2 (en) * | 2019-12-31 | 2024-08-06 | Mcafee, Llc | Device identification |
| KR102263984B1 (ko) * | 2020-02-21 | 2021-06-11 | 재단법인 아산사회복지재단 | 직장암 환자에서 수술-전 화학방사선치료의 반응을 예측하기 위한 분석방법 |
| KR102535150B1 (ko) * | 2020-04-14 | 2023-05-23 | 주식회사 베르티스 | 암의 예후 예측용 조성물 |
| EP4143309A4 (en) * | 2020-04-29 | 2025-01-01 | Freenome Holdings, Inc. | Rna markers and methods for identifying colon cell proliferative disorders |
| GB202010970D0 (en) | 2020-07-16 | 2020-09-02 | Immunovia Ab | Methods, arrays and uses thereof |
| CN112322730B (zh) * | 2020-10-16 | 2023-04-18 | 上海市第一人民医院 | 预测肿瘤耐药、复发的标志物kifc1及其抑制剂和应用 |
| EP4026918A1 (en) * | 2021-01-12 | 2022-07-13 | Koninklijke Philips N.V. | Prediction of an outcome of a colorectal cancer subject |
| CN113667673B (zh) * | 2021-07-15 | 2024-02-06 | 武汉血液中心 | 一种类孟买血型FUT1 236delG等位基因及其检测方法和应用 |
| KR20230059642A (ko) * | 2021-10-26 | 2023-05-03 | 사회복지법인 삼성생명공익재단 | miRNA를 포함하는 대장암의 치료 및 전이 억제용 조성물 및 이의 용도 |
| CN116735874B (zh) * | 2022-03-11 | 2025-09-23 | 上海市免疫学研究所 | 结直肠癌肿瘤边界细胞亚群标志物组合及其应用 |
| WO2024035653A1 (en) * | 2022-08-06 | 2024-02-15 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Predictive biomarker in avastin in colon cancer |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020172987A1 (en) | 1998-02-12 | 2002-11-21 | Terstappen Leon W.M.M. | Methods and reagents for the rapid and efficient isolation of circulating cancer cells |
| CA2330929A1 (en) | 1998-06-06 | 1999-12-16 | Genostic Pharma Limited | Probes used for genetic profiling |
| AU4158799A (en) | 1998-06-06 | 1999-12-30 | Genostic Pharma Limited | Probes used for genetic filing |
| EP1131470A4 (en) | 1998-10-28 | 2004-11-10 | Vysis Inc | CELLULAR NETWORKS AND METHODS FOR DETECTION AND USE OF GENETIC DISORDER MARKERS |
| EP0999016B1 (en) * | 1998-11-06 | 2001-07-11 | Temco S. R. L. | Cutter for cross cutting of webs |
| US6960439B2 (en) | 1999-06-28 | 2005-11-01 | Source Precision Medicine, Inc. | Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles |
| US6692916B2 (en) | 1999-06-28 | 2004-02-17 | Source Precision Medicine, Inc. | Systems and methods for characterizing a biological condition or agent using precision gene expression profiles |
| AU7721500A (en) | 1999-09-29 | 2001-04-30 | Human Genome Sciences, Inc. | Colon and colon cancer associated polynucleotides and polypeptides |
| CA2390687A1 (en) | 1999-12-10 | 2001-06-14 | Whitehead Institute For Biomedical Research | Metastasis genes and uses thereof |
| US7029677B2 (en) * | 2000-01-25 | 2006-04-18 | Nuvelo, Inc. | Methods of therapy and diagnosis using immunotargeting of CD84Hy1-expressing cells |
| AU2001276331A1 (en) | 2000-04-06 | 2001-10-23 | Epigenomics Ag | Diagnosis of diseases associated with metastasis |
| WO2005000087A2 (en) | 2003-06-03 | 2005-01-06 | Chiron Corporation | Gene products differentially expressed in cancerous colon cells and their methods of use ii |
| WO2002012280A2 (en) | 2000-08-03 | 2002-02-14 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of colon cancer |
| US20030166064A1 (en) | 2000-08-03 | 2003-09-04 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of colon cancer |
| WO2002012328A2 (en) | 2000-08-03 | 2002-02-14 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of colon cancer |
| US20030077568A1 (en) | 2000-09-15 | 2003-04-24 | Gish Kurt C. | Methods of diagnosis of colorectal cancer, compositions and methods of screening for colorectal cancer modulators |
| US7105293B2 (en) | 2000-09-19 | 2006-09-12 | Whitehead Institute For Biomedical Research | Genetic markers for tumors |
| AU2002246519A1 (en) | 2000-11-20 | 2002-08-06 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of colon cancer |
| WO2002074156A2 (en) * | 2001-02-02 | 2002-09-26 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of colon cancer |
| JP2005520483A (ja) * | 2001-05-09 | 2005-07-14 | ユニバーシティ ホスピタルズ オブ クリーブランド | 新規遺伝子マーカーを用いる皮膚に対する紫外線損傷の評価、それに関連する方法及び組成物 |
| US20030148314A1 (en) * | 2001-08-01 | 2003-08-07 | Millennium Pharmaceuticals, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of colon cancer |
| US7622260B2 (en) | 2001-09-05 | 2009-11-24 | The Brigham And Women's Hospital, Inc. | Diagnostic and prognostic tests |
| US6964850B2 (en) | 2001-11-09 | 2005-11-15 | Source Precision Medicine, Inc. | Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles |
| WO2003041562A2 (en) | 2001-11-14 | 2003-05-22 | Whitehead Institute For Biomedical Research | Molecular cancer diagnosis using tumor gene expression signature |
| US20030148410A1 (en) * | 2001-12-10 | 2003-08-07 | Millennium Pharmaceuticals, Inc. | Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of colon cancer |
| US20060046249A1 (en) | 2002-01-18 | 2006-03-02 | Fei Huang | Identification of polynucleotides and polypetide for predicting activity of compounds that interact with protein tyrosine kinase and or protein tyrosine kinase pathways |
| US7955800B2 (en) | 2002-06-25 | 2011-06-07 | Advpharma Inc. | Metastasis-associated gene profiling for identification of tumor tissue, subtyping, and prediction of prognosis of patients |
| EP1552293A4 (en) | 2002-09-10 | 2006-12-06 | Guennadi V Glinskii | METHOD FOR SEGREGATION OF GENES AND CLASSIFICATION OF BIOLOGICAL SAMPLES |
| WO2004110345A2 (en) | 2002-10-29 | 2004-12-23 | Pharmacia Corporation | Differentially expressed genes involved in cancer, the polypeptides encoded thereby, and methods of using the same |
| CA2516553C (en) | 2003-02-20 | 2013-04-16 | Genomic Health, Inc. | Use of intronic rna to measure gene expression |
| EP1644858B1 (en) | 2003-07-10 | 2017-12-06 | Genomic Health, Inc. | Expression profile algorithm and test for cancer prognosis |
| US20050014165A1 (en) | 2003-07-18 | 2005-01-20 | California Pacific Medical Center | Biomarker panel for colorectal cancer |
| WO2005015236A2 (en) | 2003-07-18 | 2005-02-17 | Roche Diagnostics Gmbh | A method for predicting the progression of adenocarcinoma |
| CA2533803A1 (en) * | 2003-07-29 | 2005-02-10 | Bristol-Myers Squibb Company | Biomarkers of cyclin-dependent kinase modulation |
| EP1522594A3 (en) | 2003-10-06 | 2005-06-22 | Bayer HealthCare AG | Methods and kits for investigating cancer |
| WO2005076005A2 (en) | 2004-01-30 | 2005-08-18 | Medizinische Universität Wien | A method for classifying a tumor cell sample based upon differential expression of at least two genes |
| US20060195266A1 (en) | 2005-02-25 | 2006-08-31 | Yeatman Timothy J | Methods for predicting cancer outcome and gene signatures for use therein |
| CA2562835A1 (en) | 2004-04-16 | 2005-10-27 | Monash University | A method for monitoring the progress of cancer |
| WO2006010150A2 (en) | 2004-07-15 | 2006-01-26 | University Of Utah Research Foundation | Housekeeping genes and methods for identifying the same |
| US20060183893A1 (en) | 2005-01-25 | 2006-08-17 | North Don A | Nucleic acids for apoptosis of cancer cells |
| JP2008535853A (ja) | 2005-04-07 | 2008-09-04 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス インコーポレイテッド | 癌関連遺伝子 |
| WO2006138275A2 (en) | 2005-06-13 | 2006-12-28 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| EP1954708A4 (en) | 2005-11-23 | 2009-05-13 | Univ Utah Res Found | Methods and compositions involving intrinsic genes |
| US20090215054A1 (en) | 2005-12-13 | 2009-08-27 | Carter Scott L | Prognosis indicators for solid human tumors |
| NZ544432A (en) | 2005-12-23 | 2009-07-31 | Pacific Edge Biotechnology Ltd | Prognosis prediction for colorectal cancer using a prognositc signature comprising markers ME2 and FAS |
| KR20090003178A (ko) | 2006-01-11 | 2009-01-09 | 게노믹 헬쓰, 인코포레이티드 | 직장결장암 예후에 대한 유전자 발현 마커 |
| WO2007112330A2 (en) | 2006-03-24 | 2007-10-04 | Diadexus, Inc. | Compositions and methods for detection, prognosis and treatment of colon cancer |
| CA2680591A1 (en) | 2007-03-15 | 2008-09-25 | Genomic Health, Inc. | Gene expression markers for prediction of patient response to chemotherapy |
| US8067178B2 (en) | 2008-03-14 | 2011-11-29 | Genomic Health, Inc. | Gene expression markers for prediction of patient response to chemotherapy |
| US8765383B2 (en) | 2009-04-07 | 2014-07-01 | Genomic Health, Inc. | Methods of predicting cancer risk using gene expression in premalignant tissue |
| WO2010127322A1 (en) | 2009-05-01 | 2010-11-04 | Genomic Health Inc. | Gene expression profile algorithm and test for likelihood of recurrence of colorectal cancer and response to chemotherapy |
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