PL2056842T3 - Modyfikowany galaktozyloceramid do leczenia chorób nowotworowych - Google Patents

Modyfikowany galaktozyloceramid do leczenia chorób nowotworowych

Info

Publication number
PL2056842T3
PL2056842T3 PL07760333T PL07760333T PL2056842T3 PL 2056842 T3 PL2056842 T3 PL 2056842T3 PL 07760333 T PL07760333 T PL 07760333T PL 07760333 T PL07760333 T PL 07760333T PL 2056842 T3 PL2056842 T3 PL 2056842T3
Authority
PL
Poland
Prior art keywords
modified
treatment
cancerous diseases
galactosyl ceramide
galactosyl
Prior art date
Application number
PL07760333T
Other languages
English (en)
Inventor
Paul B Savage
Luc Teyton
Albert Bendelac
Original Assignee
Scripps Research Inst
Univ Brigham Young
Univ Chicago
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst, Univ Brigham Young, Univ Chicago filed Critical Scripps Research Inst
Publication of PL2056842T3 publication Critical patent/PL2056842T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/06—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical being a hydroxyalkyl group esterified by a fatty acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PL07760333T 2006-04-07 2007-04-09 Modyfikowany galaktozyloceramid do leczenia chorób nowotworowych PL2056842T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US79009606P 2006-04-07 2006-04-07
PCT/US2007/066250 WO2007118234A2 (en) 2006-04-07 2007-04-09 Modified -galactosyl ceramides for staining and stimulating natural killer t cells
EP07760333A EP2056842B1 (en) 2006-04-07 2007-04-09 Modified-galactosyl ceramide for the treatment of cancerous diseases

Publications (1)

Publication Number Publication Date
PL2056842T3 true PL2056842T3 (pl) 2013-03-29

Family

ID=38581864

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07760333T PL2056842T3 (pl) 2006-04-07 2007-04-09 Modyfikowany galaktozyloceramid do leczenia chorób nowotworowych

Country Status (12)

Country Link
US (2) US8227581B2 (pl)
EP (1) EP2056842B1 (pl)
AU (1) AU2007234753B2 (pl)
BR (1) BRPI0710668A2 (pl)
CA (1) CA2661789C (pl)
DK (1) DK2056842T3 (pl)
ES (1) ES2397975T3 (pl)
PL (1) PL2056842T3 (pl)
PT (1) PT2056842E (pl)
SI (1) SI2056842T1 (pl)
WO (1) WO2007118234A2 (pl)
ZA (1) ZA200900905B (pl)

Families Citing this family (19)

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US7645873B2 (en) * 2003-03-20 2010-01-12 The Scripps Research Institute 6″-amino-6″-deoxygalactosylceramides
WO2006083671A2 (en) 2005-01-28 2006-08-10 Brigham Young University Bacterial glycolipid activation of cd1d-restricted nkt cells
AU2007269299B2 (en) 2006-06-30 2013-01-17 Brigham Young University Adjuvants and methods of use
US8916164B2 (en) 2007-08-29 2014-12-23 Abivax Methods of enhancing adjuvaticity of vaccine compositions
AU2013202865B2 (en) * 2007-11-07 2015-03-19 Abivax Increase of immune response and targeting by antigens and/or drug linkage
EP2058011A1 (en) 2007-11-07 2009-05-13 Wittycell Nkt cell activating gycolipids covalently bound antigens and/or drug
WO2009101475A2 (en) 2007-12-05 2009-08-20 Wittycell S.A.S. Compositions for and methods of enhancing the immune response to antigens
CN102215864A (zh) * 2008-10-08 2011-10-12 威蒂赛尔公司 用于抗流感的疫苗组合物
ES2345377B1 (es) * 2009-03-20 2011-07-21 Consejo Superior De Investigaciones Cientificas (Csis) (51%) Compuestos aminociclitoles, procedimiento de obtencion y usos.
WO2011112889A2 (en) 2010-03-12 2011-09-15 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services β-MANNOSYLCERAMIDE AND STIMULATION OF NKT CELL ANTI-TUMOR IMMUNITY
WO2013162016A1 (ja) 2012-04-26 2013-10-31 独立行政法人理化学研究所 新規カルバメート糖脂質およびその用途
WO2014001204A1 (en) 2012-06-28 2014-01-03 Universiteit Gent Galactopyranosyl derivatives useful as medicaments
EP2727929A1 (en) * 2012-10-30 2014-05-07 Wittycell Method of preparation of alpha galactosyl ceramides compounds
US20170029454A1 (en) * 2013-06-28 2017-02-02 The Scripps Research Institute Nkt cell ligands and methods of use
US10046046B2 (en) * 2014-06-05 2018-08-14 Victoria Link Limited Amino sphingoglycolipid analogues
BR112019004906A2 (pt) * 2016-09-14 2019-06-25 Abivax combinação incluindo abx196 para o tratamento de câncer
WO2019190986A1 (en) * 2018-03-26 2019-10-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services 3-o-sulfo-galactosylceramide analogs as activators of type ii nkt cells and uses thereof
US20250049904A1 (en) * 2021-12-24 2025-02-13 Victoria Link Limited Immunostimulatory compositions
CN115286667B (zh) * 2022-08-02 2024-03-26 华中农业大学 一种α-半乳糖基神经酰胺类似物及其制备方法和应用

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US5242800A (en) 1990-01-30 1993-09-07 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Receptor for pathogenic fungi
US5936076A (en) 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives
TW261533B (pl) 1992-07-16 1995-11-01 Kirin Brewery
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US6054433A (en) * 1994-11-03 2000-04-25 The Regents Of The University Of California Methods and compositions for stimulating tissue growth and epithelial moisturization
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EP0821068A3 (en) 1996-03-29 1999-06-02 Rohm And Haas Company Novel sphingolipids and a process thereto
US6417167B1 (en) 1997-02-05 2002-07-09 Kirin Beer Kabushiki Kaisha Lyophilized compositions containing shingoglycolipid and process for preparing them
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CN1222293C (zh) * 1997-04-10 2005-10-12 麒麟麦酒株式会社 含有α－糖基神经酰胺的NKT细胞活化剂
CA2316041A1 (en) 1997-12-30 1999-07-08 Pam Fredman Galactosylceramide, glucosylceramide, lactosylceramide, and specific catchers therefor for use in the prophylaxis or therapy of prediabetes, diabetes and/or associated complications
US6610835B1 (en) 1998-02-12 2003-08-26 Emory University Sphingolipid derivatives and their methods of use
US20030157113A1 (en) * 1999-12-28 2003-08-21 Terman David S. Compositions and methods for treatment of neoplastic disease
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AU2002327338A1 (en) 2001-07-25 2003-02-17 New York University Use of glycosylceramides as adjuvants for vaccines against infections and cancer
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CA2519568C (en) * 2003-03-20 2012-01-03 Brigham Young University 6"-amino-6"-deoxygalactosylceramides
US7645873B2 (en) * 2003-03-20 2010-01-12 The Scripps Research Institute 6″-amino-6″-deoxygalactosylceramides
GB0314682D0 (en) 2003-06-24 2003-07-30 Isis Innovation Materials and methods relating to the modulation of T cell response to soluble antigen
US7771726B2 (en) 2003-10-08 2010-08-10 New York University Use of synthetic glycolipids as universal adjuvants for vaccines against cancer and infectious diseases
AU2005235080A1 (en) 2004-03-31 2005-11-03 New York University Novel synthetic C-glycolipids, their synthesis and use to treat infections, cancer and autoimmune diseases
US7772380B2 (en) 2004-08-27 2010-08-10 Albert Einstein College Of Medicine Of Yeshiva University Ceramide derivatives as modulators of immunity and autoimmunity
AU2005282684B9 (en) 2004-09-03 2011-07-07 Brigham Young University Methods of activating NKT cells
WO2006071848A2 (en) 2004-12-28 2006-07-06 The Rockefeller University Glycolipids and analogues thereof as antigens for nk t cells
WO2006083671A2 (en) 2005-01-28 2006-08-10 Brigham Young University Bacterial glycolipid activation of cd1d-restricted nkt cells
KR100764678B1 (ko) 2005-07-13 2007-10-09 재단법인서울대학교산학협력재단 알파-갈락토실세라마이드를 아쥬반트로 포함하는 비강투여용 백신 조성물
US8039670B2 (en) 2005-10-25 2011-10-18 Ludwig Institute For Cancer Research Analogs of alpha galactosyceramide and uses thereof
AU2007269299B2 (en) 2006-06-30 2013-01-17 Brigham Young University Adjuvants and methods of use
EP1938836A1 (en) 2006-12-28 2008-07-02 Universite Rene Descartes (Paris V) Compositions comprising a B subunit of shiga toxin and a means stimulating NKT cells

Also Published As

Publication number Publication date
EP2056842A4 (en) 2010-10-06
ZA200900905B (en) 2010-06-30
EP2056842B1 (en) 2012-10-17
ES2397975T3 (es) 2013-03-12
SI2056842T1 (sl) 2013-02-28
AU2007234753B2 (en) 2013-02-21
AU2007234753A1 (en) 2007-10-18
DK2056842T3 (da) 2013-01-14
PT2056842E (pt) 2013-01-24
WO2007118234A2 (en) 2007-10-18
US20120270815A1 (en) 2012-10-25
BRPI0710668A2 (pt) 2011-08-16
US20090047299A1 (en) 2009-02-19
US8765692B2 (en) 2014-07-01
CA2661789A1 (en) 2007-10-18
WO2007118234A3 (en) 2007-12-06
EP2056842A2 (en) 2009-05-13
US8227581B2 (en) 2012-07-24
CA2661789C (en) 2014-06-03

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