IL164267A0 - Piperazinyl-or piperidinylamine-sulfamic acid amides as inhibitors of steroid sulfatase - Google Patents

Piperazinyl-or piperidinylamine-sulfamic acid amides as inhibitors of steroid sulfatase

Info

Publication number
IL164267A0
IL164267A0 IL16426703A IL16426703A IL164267A0 IL 164267 A0 IL164267 A0 IL 164267A0 IL 16426703 A IL16426703 A IL 16426703A IL 16426703 A IL16426703 A IL 16426703A IL 164267 A0 IL164267 A0 IL 164267A0
Authority
IL
Israel
Prior art keywords
piperidinylamine
piperazinyl
inhibitors
acid amides
sulfamic acid
Prior art date
Application number
IL16426703A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0207500A external-priority patent/GB0207500D0/en
Priority claimed from GB0225679A external-priority patent/GB0225679D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL164267A0 publication Critical patent/IL164267A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IL16426703A 2002-03-28 2003-03-27 Piperazinyl-or piperidinylamine-sulfamic acid amides as inhibitors of steroid sulfatase IL164267A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0207500A GB0207500D0 (en) 2002-03-28 2002-03-28 Organic compounds
GB0225679A GB0225679D0 (en) 2002-11-04 2002-11-04 Organic compounds
PCT/EP2003/003214 WO2003082842A1 (en) 2002-03-28 2003-03-27 Piperazinyl- or piperidinylamine-sulfamic acid amides as inhibitors of steroid sulfatase

Publications (1)

Publication Number Publication Date
IL164267A0 true IL164267A0 (en) 2005-12-18

Family

ID=28676499

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16426703A IL164267A0 (en) 2002-03-28 2003-03-27 Piperazinyl-or piperidinylamine-sulfamic acid amides as inhibitors of steroid sulfatase

Country Status (20)

Country Link
US (2) US7439362B2 (ja)
EP (1) EP1492782A1 (ja)
JP (1) JP4580652B2 (ja)
KR (1) KR20040094877A (ja)
CN (1) CN1293065C (ja)
AR (1) AR039156A1 (ja)
AU (1) AU2003226732B2 (ja)
BR (1) BR0308795A (ja)
CA (1) CA2480686A1 (ja)
CO (1) CO5640113A2 (ja)
IL (1) IL164267A0 (ja)
MX (1) MXPA04009453A (ja)
MY (1) MY136880A (ja)
NO (1) NO20044321L (ja)
NZ (1) NZ535617A (ja)
PE (1) PE20040167A1 (ja)
PL (1) PL372602A1 (ja)
RU (1) RU2329258C2 (ja)
TW (1) TW200306806A (ja)
WO (1) WO2003082842A1 (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0505541D0 (en) * 2005-03-17 2005-04-27 Novartis Ag Organic compounds
GB0505539D0 (en) * 2005-03-17 2005-04-27 Novartis Ag Organic compounds
GB0511190D0 (en) * 2005-06-01 2005-07-06 Sterix Ltd Use
EP2207544A2 (en) 2007-09-17 2010-07-21 PregLem S.A. Treatment of oestrogen dependant conditions in pre-menopausal women
CN109152844B (zh) * 2016-02-08 2022-11-22 西纳福克斯股份有限公司 用于治疗的含有磺酰胺接头的生物缀合物
EP3413915A1 (en) 2016-02-08 2018-12-19 Synaffix B.V. Antibody-conjugates with improved therapeutic index for targeting her2 tumours and method for improving therapeutic index of antibody-conjugates
EP3413922A1 (en) 2016-02-08 2018-12-19 SynAffix B.V. Improved sulfamide linkers for use in bioconjugates
JP2020502064A (ja) * 2016-11-29 2020-01-23 エピザイム，インコーポレイティド スルホン酸基を含むｋａｔ阻害剤としての化合物
EP3983388A1 (en) * 2019-06-12 2022-04-20 Nodthera Limited Sulfonamide derivatives and uses thereof
CN110590896B (zh) * 2019-11-04 2022-08-30 上海高准医药有限公司 雌酚酮硫酸酯哌嗪的制备方法

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US183459A (en) * 1876-10-17 Improvement in hinges
US89089A (en) * 1869-04-20 Improved car-coupling
US478328A (en) * 1892-07-05 Glass-heating oven
US51547A (en) * 1865-12-19 Improvement in guide and tuck-marker for sewing-machines
US71516A (en) * 1867-11-26 William b
US876846A (en) * 1907-05-28 1908-01-14 Stephen W Smith Road-machine.
US1122242A (en) * 1912-05-13 1914-12-29 Sanitary Can Company Can-body-feeding device.
US2103610A (en) * 1935-04-30 1937-12-28 Sofal Ltd Alloy steels
DE876846C (de) * 1943-06-01 1953-05-18 Bayer Ag Verfahren zur Herstellung von Abkoemmlingen des Sulfondiamids
US3004487A (en) * 1959-12-07 1961-10-17 Bank Of America Nat Trust & Savings Ass Imprinters
GB1593609A (en) * 1978-01-31 1981-07-22 Christiaens Sa A Pyridine sulfonamides
FR2510106A1 (fr) 1981-07-27 1983-01-28 Rhone Poulenc Agrochimie Composes herbicides derives d'acides phenoxybenzoiques, et leurs procedes de preparation et d'utilisation
DK101683A (da) * 1982-03-12 1983-09-13 Duphar Int Res Phenylpiperazinderivater og fremgangsmaade til fremstilling heraf
US5238923A (en) * 1989-05-26 1993-08-24 Warner-Lambert Company Amino-substituted heterocycles as renin inhibitors
US5256632A (en) * 1990-05-30 1993-10-26 Bayer Aktiengesellschaft Herbicidal sulphonylated carboxamides
IL99537A (en) 1990-09-27 1995-11-27 Merck & Co Inc Fibrinogen receptor antagonists and pharmaceutical preparations containing them
FR2716882B1 (fr) * 1994-03-04 1996-04-05 Roussel Uclaf Utilisation de dérivés de l'imidazole au traitement d'affections impliquant les récepteurs AT1 et AT2 de l'Angiotensine, certains de ces produits, leur préparation, compositions pharmaceutiques.
FR2716883B1 (fr) * 1994-03-04 1996-04-26 Roussel Uclaf Nouveaux dérivés tétrasubstitués de l'imidazole, leur préparation, nouveaux intermédiaires obtenus, leur application à titre de médicaments, compositions pharmaceutiques les renfermant.
US5464788A (en) 1994-03-24 1995-11-07 Merck & Co., Inc. Tocolytic oxytocin receptor antagonists
WO1996002530A1 (en) 1994-07-20 1996-02-01 Merck & Co., Inc. Piperidines and hexahydro-1h-azepines spiro substituted at the 4-position promote release of growth hormone
KR970706242A (ko) 1994-10-04 1997-11-03 후지야마 아키라 우레아 유도체 및 ACAT-억제제로서 그의 용도(Urea derivatives and their use as ACAT-inhibitors)
WO1997020820A1 (en) 1995-12-01 1997-06-12 Novartis Ag Heteroaryl compounds
DE19621483A1 (de) * 1996-05-29 1997-12-04 Hoechst Ag Substituierte 2-Naphthoylguanidine, Verfahren zur ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19621482A1 (de) * 1996-05-29 1997-12-04 Hoechst Ag Substituierte 1-Naphthoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
EP0977772A1 (en) 1997-04-14 2000-02-09 Cor Therapeutics, Inc. SELECTIVE FACTOR Xa INHIBITORS
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JP2002542155A (ja) 1999-03-03 2002-12-10 メルク エンド カムパニー インコーポレーテッド プレニル蛋白トランスフェラーゼの阻害剤
AU5283600A (en) 1999-05-24 2000-12-12 Cor Therapeutics, Inc. Inhibitors of factor xa
JP4320089B2 (ja) * 1999-07-06 2009-08-26 あすか製薬株式会社 フェニルスルファメート誘導体
US6632815B2 (en) * 1999-09-17 2003-10-14 Millennium Pharmaceuticals, Inc. Inhibitors of factor Xa
IL148464A0 (en) 2000-05-04 2002-09-12 Basf Ag Uracil substituted phenyl sulfamoyl carboxamides
JP2005505506A (ja) * 2001-06-12 2005-02-24 イーラン ファーマスーティカルズ、インコーポレイテッド アルツハイマー病の治療に有用な大環状分子
BR0210733A (pt) 2001-07-02 2004-07-20 Astrazeneca Ab Derivados de piperidina de utilidade úteis como moduladores da atividade do receptor de quimocina

Also Published As

Publication number Publication date
CO5640113A2 (es) 2006-05-31
US20090042899A1 (en) 2009-02-12
US7439362B2 (en) 2008-10-21
US20060052393A1 (en) 2006-03-09
MXPA04009453A (es) 2005-01-25
CN1293065C (zh) 2007-01-03
AU2003226732B2 (en) 2006-12-21
EP1492782A1 (en) 2005-01-05
TW200306806A (en) 2003-12-01
RU2329258C2 (ru) 2008-07-20
PL372602A1 (en) 2005-07-25
JP4580652B2 (ja) 2010-11-17
RU2004131822A (ru) 2005-07-10
AR039156A1 (es) 2005-02-09
BR0308795A (pt) 2005-01-18
WO2003082842A1 (en) 2003-10-09
CA2480686A1 (en) 2003-10-09
AU2003226732A1 (en) 2003-10-13
MY136880A (en) 2008-11-28
PE20040167A1 (es) 2004-05-26
CN1646509A (zh) 2005-07-27
NZ535617A (en) 2006-04-28
KR20040094877A (ko) 2004-11-10
NO20044321L (no) 2004-10-12
JP2005526812A (ja) 2005-09-08

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