IL163685A0 - Bipolar trans carotenoid salts and their uses - Google Patents

Bipolar trans carotenoid salts and their uses

Info

Publication number
IL163685A0
IL163685A0 IL16368503A IL16368503A IL163685A0 IL 163685 A0 IL163685 A0 IL 163685A0 IL 16368503 A IL16368503 A IL 16368503A IL 16368503 A IL16368503 A IL 16368503A IL 163685 A0 IL163685 A0 IL 163685A0
Authority
IL
Israel
Prior art keywords
trans carotenoid
bipolar trans
carotenoid salts
salts
bipolar
Prior art date
Application number
IL16368503A
Other languages
English (en)
Original Assignee
Diffusion Pharmaceuticals Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diffusion Pharmaceuticals Llc filed Critical Diffusion Pharmaceuticals Llc
Publication of IL163685A0 publication Critical patent/IL163685A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
    • C07C69/602—Dicarboxylic acid esters having at least two carbon-to-carbon double bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/06—Potassium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C305/00—Esters of sulfuric acids
    • C07C305/02—Esters of sulfuric acids having oxygen atoms of sulfate groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C305/14—Esters of sulfuric acids having oxygen atoms of sulfate groups bound to acyclic carbon atoms of a carbon skeleton being acyclic and unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13—Dicarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/04—Sodium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/113—Esters of phosphoric acids with unsaturated acyclic alcohols

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Toxicology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL16368503A 2002-02-25 2003-02-25 Bipolar trans carotenoid salts and their uses IL163685A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35871802P 2002-02-25 2002-02-25
PCT/US2003/005521 WO2003072734A2 (fr) 2002-02-25 2003-02-25 Sels carotenoides trans bipolaires et leurs utilisations

Publications (1)

Publication Number Publication Date
IL163685A0 true IL163685A0 (en) 2005-12-18

Family

ID=27765977

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16368503A IL163685A0 (en) 2002-02-25 2003-02-25 Bipolar trans carotenoid salts and their uses

Country Status (19)

Country Link
US (4) US7351844B2 (fr)
EP (1) EP1487774B1 (fr)
JP (4) JP2005518453A (fr)
KR (1) KR101020115B1 (fr)
CN (1) CN1671643B (fr)
AU (1) AU2003215396B2 (fr)
BR (1) BR0307935A (fr)
CA (1) CA2477245A1 (fr)
CZ (1) CZ2004904A3 (fr)
EA (1) EA200401111A1 (fr)
HU (1) HUP0500134A3 (fr)
IL (1) IL163685A0 (fr)
MX (1) MXPA04008253A (fr)
NO (1) NO20043661L (fr)
NZ (2) NZ564486A (fr)
PL (1) PL373780A1 (fr)
UA (1) UA83341C2 (fr)
WO (1) WO2003072734A2 (fr)
ZA (1) ZA200406673B (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL163685A0 (en) * 2002-02-25 2005-12-18 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
US7759506B2 (en) 2002-02-25 2010-07-20 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
AU2011265546B2 (en) * 2003-08-25 2016-05-12 Diffusion Pharmaceuticals Llc Bipolar Trans Carotenoid Salts and Their Uses
JP2007522076A (ja) * 2003-08-25 2007-08-09 ディフュージョン・ファーマシューティカルズ・エルエルシー 双極性トランスカロテノイド塩及びそれらの使用
EA017982B1 (ru) 2005-02-24 2013-04-30 ДИФФЬЮЖН ФАРМАСЬЮТИКАЛЗ ЭлЭлСи Фармацевтическая композиция на основе транскаротиноидов и способы лечения опухоли
WO2006112283A1 (fr) * 2005-04-13 2006-10-26 Riken Vitamin Co., Ltd. Agent anti-fatigue
US7855193B2 (en) * 2005-11-23 2010-12-21 Epix Pharmaceuticals, Inc. S1P receptor modulating compounds and use thereof
US20070288322A1 (en) * 2006-05-23 2007-12-13 Toshiba Tec Kabushiki Kaisha Portable terminal and its programs, settlement apparatus, and merchandising information providing apparatus
EP2146948A4 (fr) 2007-04-13 2010-08-04 Diffusion Pharmaceuticals Llc Utilisation de transcaroténoïdes bipolaires en tant que traitement préalable et dans le traitement de pathologies vasculaires périphériques
RU2010101236A (ru) * 2007-06-19 2011-07-27 Новартис АГ (CH) Органические соединения
AU2008319225B2 (en) 2007-10-31 2016-09-29 Diffusion Pharmaceuticals Llc A new class of therapeutics that enhance small molecule diffusion
CN101157645B (zh) * 2007-11-27 2010-06-02 江南大学 一种藏红花酸的合成方法
US10130689B2 (en) 2009-06-22 2018-11-20 Diffusion Pharmaceuticals Llc Diffusion enhancing compounds and their use alone or with thrombolytics
JP2010090151A (ja) * 2009-12-09 2010-04-22 Diffusion Pharmaceuticals Llc 双極性トランスカロテノイド塩及びそれらの使用
EP2575487B1 (fr) 2010-06-02 2017-10-18 Diffusion Pharmaceuticals Llc Formes pharmaceutiques orales à base de caroténoïdes trans bipolaires
CN101967087A (zh) * 2010-09-21 2011-02-09 上海大学 (e)- 4.4-二甲氧基-2-丁烯醛的制备方法
CN103172504B (zh) * 2011-12-26 2014-10-08 南京工业大学 2,7-二甲基-2,4,6-辛三烯-1,8-二醛的合成方法
EP3432929A4 (fr) 2016-03-24 2019-11-27 Diffusion Pharmaceuticals LLC Utilisation de caroténoïdes trans bipolaires avec une chimiothérapie et une radiothérapie en vue du traitement d'un cancer
WO2021207650A1 (fr) * 2020-04-09 2021-10-14 L.E.A.F. Holdings Group Llc Compositions de trans-crocétine et régimes de traitement
US20240316000A1 (en) * 2021-06-29 2024-09-26 Diffusion Pharmaceuticals Llc Methods of treatment
WO2023081779A1 (fr) * 2021-11-03 2023-05-11 Diffusion Pharmaceuticals Llc Formes cristallines d'un composé améliorant la diffusion
CN114534729B (zh) * 2022-03-07 2024-05-03 万华化学集团股份有限公司 一种催化剂及其制备方法和其在电化学法制备β-胡萝卜素中的应用

Family Cites Families (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2948748A (en) * 1960-08-09 Esters thereof
US2175843A (en) * 1936-06-26 1939-10-10 Winthrop Chem Co Inc Polyene carboxylic acids and esters and manufacture thereof
CH468330A (de) 1966-01-28 1969-02-15 Hoffmann La Roche Verfahren zur Herstellung von isoprenoiden Verbindungen
US3489806A (en) 1967-01-19 1970-01-13 Hoffmann La Roche Isoprenoid compounds and a process for producing the same
CH522572A (de) 1969-10-31 1972-06-30 Hoffmann La Roche Verfahren zur Herstellung von Polyenverbindungen
US3788468A (en) * 1973-05-01 1974-01-29 Univ Virginia Process for increasing oxygen diffusivity
US3853993A (en) * 1973-05-01 1974-12-10 Univ Virginia Process for increasing oxygen diffusivity and method for treating atherosclerosis
US3853933A (en) * 1974-01-14 1974-12-10 Gen Electric Continuous process for producing polysiloxane oils utilizing a carbon black catalyst
DE2505869C3 (de) * 1975-02-12 1978-05-18 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von symmetrischen Carotinoiden
US3965261A (en) * 1975-04-29 1976-06-22 University Of Virginia Method for treating papillomas
US3975519A (en) * 1975-06-09 1976-08-17 University Of Virginia Method for increasing the oxygen partial pressure in the bloodstream of mammals
US4070460A (en) * 1975-11-10 1978-01-24 University Of Virginia Patents Foundation Method for treating cerebral edema
US4009270A (en) * 1975-11-21 1977-02-22 The University Of Virginia Method for treating spinal cord injury
US4038144A (en) * 1976-04-19 1977-07-26 The University Of Virginia Method of increasing fermentation yields
US4046880A (en) * 1976-04-20 1977-09-06 The University Of Virginia Method of treating hypertension
US4068144A (en) * 1976-09-20 1978-01-10 Recognition Equipment Incorporated Liquid jet modulator with piezoelectric hemispheral transducer
US4099270A (en) * 1977-02-16 1978-07-11 Jabour Richard J Slip-on rubber gloves
US4216211A (en) * 1977-10-31 1980-08-05 The Procter & Gamble Company Therapeutic composition
US4176179A (en) * 1978-04-17 1979-11-27 The University Of Virginia Alumni Patents Foundation Method for treating arthritis
US4699664A (en) 1985-05-01 1987-10-13 Nestec S.A. Stabilized natural pigment complexes
US5032613A (en) * 1986-02-12 1991-07-16 W. Keith R. Watson Method and composition for treating arthritis
JPH0661211B2 (ja) * 1986-08-29 1994-08-17 花王株式会社 パン用改質剤、パン生地及びパンの製造方法
US5811119A (en) 1987-05-19 1998-09-22 Board Of Regents, The University Of Texas Formulation and use of carotenoids in treatment of cancer
US5472946A (en) 1988-04-08 1995-12-05 Peck; James V. Transdermal penetration enhancers
FR2647343B1 (fr) 1989-05-24 1994-05-06 Rhone Poulenc Sante Nouvelle forme pharmaceutique poreuse et sa preparation
IT1233303B (it) 1989-06-07 1992-03-26 Azionaria Costruzioni Acma Spa Apparecchiatura per il convogliamento di prodotti
US5053240A (en) 1989-10-24 1991-10-01 Kalamazoo Holdings, Inc. Norbixin adducts with water-soluble or water-dispersible proteins or branched-chain or cyclic polysaccharides
US5175843A (en) * 1989-10-30 1992-12-29 General Electric Company Computer-aided design method for restructuring computational networks to minimize shimming delays
JPH04264020A (ja) 1991-02-18 1992-09-18 Yamanouchi Pharmaceut Co Ltd 安定な凍結乾燥製剤
US5107030A (en) 1991-03-04 1992-04-21 Loyola University Of Chicago Method of making 2,7-dimethyl-2,4,6-octatrienedial and derivatives thereof
JP3176716B2 (ja) 1991-06-21 2001-06-18 武田薬品工業株式会社 溶解性が向上した難水溶性薬物組成物
JP2977961B2 (ja) * 1991-07-26 1999-11-15 株式会社資生堂 化粧料
JPH06248193A (ja) 1993-02-25 1994-09-06 Ensuiko Sugar Refining Co Ltd クロセチン含有着色料
IL110139A0 (en) 1993-06-28 1994-10-07 Howard Foundation Pharmaceutically-active antioxidants
JPH0723736A (ja) 1993-06-30 1995-01-27 Taishiyoo Technos:Kk カロチノイド色素の可溶化方法
JP2704356B2 (ja) 1994-02-08 1998-01-26 正和薬品株式会社 脳機能改善剤
JPH07291854A (ja) 1994-04-26 1995-11-07 Tanabe Seiyaku Co Ltd 溶解性の改善された医薬品製剤
GB2290964A (en) 1994-07-08 1996-01-17 Arto Olavi Urtti Transdermal drug delivery system
US6060511A (en) 1995-10-05 2000-05-09 Gainer; John L. Trans-sodium crocetinate, methods of making and methods of use thereof
US6090771A (en) * 1996-10-24 2000-07-18 Reckitt Benckiser Inc. Low residue aqueous hard surface cleaning and disinfecting compositions
RU2107496C1 (ru) 1997-02-10 1998-03-27 Российская медицинская академия последипломного образования Министерства здравоохранения РФ Способ лечения диабетической ангиопатии
US6391336B1 (en) 1997-09-22 2002-05-21 Royer Biomedical, Inc. Inorganic-polymer complexes for the controlled release of compounds including medicinals
US6150561A (en) * 1997-10-03 2000-11-21 Roche Vitamins Inc. Method of making carotenoids
JPH11209642A (ja) 1998-01-27 1999-08-03 Taito Kk アナトー色素製剤及びその製造方法
MA25590A1 (fr) 1998-09-14 2002-12-31 Inhale Therapeutic Syst Agent actif de delivraison de poudre seche
BE1012495A3 (fr) * 1999-03-02 2000-11-07 Messadek Jallal La glycine-betaine pour son usage antithrombotique.
CA2355814C (fr) 2000-09-14 2010-06-29 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Composition pharmaceutique pour utilisation ophthalmologique
IL163685A0 (en) 2002-02-25 2005-12-18 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
US7759506B2 (en) 2002-02-25 2010-07-20 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
US20030180282A1 (en) 2002-03-25 2003-09-25 Victor Serebruany Method of treatment of thrombotic events
RU2226096C1 (ru) 2002-07-01 2004-03-27 Санкт-Петербургский государственный научно-исследовательский институт скорой помощи им. И.И.Джанелидзе Способ лечения последствий тканевой гипоксии у пациентов в критическом состоянии
US7145025B2 (en) * 2002-07-29 2006-12-05 Hawaii Biotech, Inc. Structural carotenoid analogs for the inhibition and amelioration of disease
DE10254809A1 (de) 2002-11-22 2004-06-03 Basf Ag Verfahren zur Herstellung von Carotinoiden
DE60238283D1 (de) 2002-11-25 2010-12-23 Jallal Messadek Betain und Salicylsäure Zusammensetzungen
US20040109920A1 (en) 2002-12-04 2004-06-10 Bioactives Llc Coated carotenoid cyclodextrin complexes
JP2007522076A (ja) 2003-08-25 2007-08-09 ディフュージョン・ファーマシューティカルズ・エルエルシー 双極性トランスカロテノイド塩及びそれらの使用
RU2265434C2 (ru) 2003-09-30 2005-12-10 Государственное учреждение Научно-исследовательский Институт Общей реаниматологии Российской Академии Медицинских Наук (ГУ НИИ ОР РАМН) Способ лечения острого респираторного дистресс-синдрома
RU2256446C1 (ru) 2003-10-22 2005-07-20 Государственное учреждение Межотраслевой научно-технический комплекс "Микрохирургия глаза" им. акад. С.Н. Федорова Способ профилактики метастазов после хирургического удаления внутриглазных новообразований
US7446101B1 (en) 2003-12-12 2008-11-04 Bioactives, Llc Bioavailable carotenoid-cyclodextrin formulations for soft-gels and other encapsulation systems
AU2005251463A1 (en) 2004-06-14 2005-12-22 Zoser B. Salama Anti-cancer composition comprising proline or its derivatives and an anti-tumour antibody
JP4514114B2 (ja) 2004-06-18 2010-07-28 ヤマハ発動機株式会社 コイル可動形リニアモータおよび単軸ロボット
CA2581764A1 (fr) 2004-09-27 2006-04-06 Sigmoid Biotechnologies Limited Formulations comprenant des minicapsules
US20060167319A1 (en) 2004-10-01 2006-07-27 Lockwood Samuel F Methods for the synthesis of unsaturated ketone intermediates useful for the synthesis of carotenoids
US20090176287A1 (en) 2005-02-24 2009-07-09 Regents Of The University Of Minnesota Producing carotenoids
EA017982B1 (ru) 2005-02-24 2013-04-30 ДИФФЬЮЖН ФАРМАСЬЮТИКАЛЗ ЭлЭлСи Фармацевтическая композиция на основе транскаротиноидов и способы лечения опухоли
WO2006099015A2 (fr) 2005-03-09 2006-09-21 Cardax Pharmaceuticals, Inc. Carotenoides, analogues de carotenoides ou derives de carotenoides permettant de traiter les troubles proliferatifs
CA2620943A1 (fr) 2005-09-02 2007-03-08 Iomai Corporation Dispositifs d'administration transcutanee de vaccins et d'administration transdermique de medicaments et utilisations idoines
ITMI20052486A1 (it) 2005-12-23 2007-06-24 Italiana Sint Spa Procedimento di sintesi di intermedi per la preparazione di astaxantina
WO2007109824A1 (fr) 2006-03-24 2007-10-04 Ian Simon Tracton Forme de dosage emballée stable et procédé pour celle-ci
EP2146948A4 (fr) 2007-04-13 2010-08-04 Diffusion Pharmaceuticals Llc Utilisation de transcaroténoïdes bipolaires en tant que traitement préalable et dans le traitement de pathologies vasculaires périphériques
AU2008319225B2 (en) 2007-10-31 2016-09-29 Diffusion Pharmaceuticals Llc A new class of therapeutics that enhance small molecule diffusion

Also Published As

Publication number Publication date
EA200401111A1 (ru) 2005-02-24
US20070161610A1 (en) 2007-07-12
US7351844B2 (en) 2008-04-01
WO2003072734A3 (fr) 2004-03-18
CZ2004904A3 (cs) 2004-12-15
EP1487774A2 (fr) 2004-12-22
AU2003215396A1 (en) 2003-09-09
JP2010106029A (ja) 2010-05-13
US8269027B2 (en) 2012-09-18
NZ535323A (en) 2008-02-29
NZ564486A (en) 2009-03-31
EP1487774B1 (fr) 2018-09-19
WO2003072734A2 (fr) 2003-09-04
KR20040097133A (ko) 2004-11-17
HUP0500134A2 (en) 2006-09-28
JP5774655B2 (ja) 2015-09-09
AU2003215396B2 (en) 2010-04-08
CN1671643B (zh) 2013-05-29
CA2477245A1 (fr) 2003-09-04
CN1671643A (zh) 2005-09-21
US20140051759A1 (en) 2014-02-20
HUP0500134A3 (en) 2009-12-28
PL373780A1 (en) 2005-09-19
JP2014040435A (ja) 2014-03-06
KR101020115B1 (ko) 2011-03-08
NO20043661L (no) 2004-09-01
EP1487774A4 (fr) 2018-04-25
UA83341C2 (uk) 2008-07-10
MXPA04008253A (es) 2005-04-19
ZA200406673B (en) 2007-02-28
US20040014725A1 (en) 2004-01-22
US20070203353A1 (en) 2007-08-30
JP2010229137A (ja) 2010-10-14
BR0307935A (pt) 2005-03-29
JP2005518453A (ja) 2005-06-23

Similar Documents

Publication Publication Date Title
IL220295A0 (en) Bipolar trans carotenoid salts and their uses
IL163685A0 (en) Bipolar trans carotenoid salts and their uses
GB2391135B (en) User group creation
AU2003258255A8 (en) Send-reply label
AU2003259271A1 (en) Bipolar articles and related methods
PL372902A1 (en) New use
SI1556029T1 (sl) Soli tiomolibdata in njihova uporaba
AU148618S (en) Wok
GB0302935D0 (en) Labels
GB0209391D0 (en) Mannequin head
GB2386467B (en) Bipolar plates
AU2003282765A8 (en) Multihued labels
GB0229124D0 (en) Signs
GB0208941D0 (en) Label
EP1476818A4 (fr) Agregation a faible chargement de processeur
GB0215357D0 (en) Sterilisation
AU2003207669A1 (en) Low-processor-load aggregation
PL113329U1 (en) Label
GB0225863D0 (en) Label
GB0230157D0 (en) Label
AUPS107302A0 (en) Tags
GB0225116D0 (en) Fashion designer label
GB0229125D0 (en) Signage
GB0203094D0 (en) Individual traction table
AU2002951074A0 (en) Labels