IL163579A0 - Pharmaceutical compositions comprising one or moresteroids oneor more tetrahydrofolate components and vitamin B12 - Google Patents

Pharmaceutical compositions comprising one or moresteroids oneor more tetrahydrofolate components and vitamin B12

Info

Publication number
IL163579A0
IL163579A0 IL16357902A IL16357902A IL163579A0 IL 163579 A0 IL163579 A0 IL 163579A0 IL 16357902 A IL16357902 A IL 16357902A IL 16357902 A IL16357902 A IL 16357902A IL 163579 A0 IL163579 A0 IL 163579A0
Authority
IL
Israel
Prior art keywords
tetrahydrofolic acid
vitamin
tetrahydrofolic
dosage units
tetrahydrofolate components
Prior art date
Application number
IL16357902A
Other languages
English (en)
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of IL163579A0 publication Critical patent/IL163579A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
IL16357902A 2002-02-21 2002-11-15 Pharmaceutical compositions comprising one or moresteroids oneor more tetrahydrofolate components and vitamin B12 IL163579A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02075695 2002-02-21
PCT/NL2002/000741 WO2003070255A1 (en) 2002-02-21 2002-11-15 Pharmaceutical compositions comprising one or more steroids one or more tetrahydrofolate components and vitamin b12

Publications (1)

Publication Number Publication Date
IL163579A0 true IL163579A0 (en) 2005-12-18

Family

ID=27741182

Family Applications (2)

Application Number Title Priority Date Filing Date
IL16357902A IL163579A0 (en) 2002-02-21 2002-11-15 Pharmaceutical compositions comprising one or moresteroids oneor more tetrahydrofolate components and vitamin B12
IL163579A IL163579A (en) 2002-02-21 2004-08-17 Kit for use in hormonal contraceptive method or hormone replacement therapy

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL163579A IL163579A (en) 2002-02-21 2004-08-17 Kit for use in hormonal contraceptive method or hormone replacement therapy

Country Status (29)

Country Link
US (1) US20050164977A1 (xx)
EP (1) EP1478373B1 (xx)
JP (1) JP5037779B2 (xx)
KR (1) KR100936827B1 (xx)
CN (1) CN1620302B (xx)
AT (1) ATE341333T1 (xx)
AU (1) AU2002343249B2 (xx)
BR (1) BR0215613A (xx)
CA (1) CA2476940C (xx)
CR (1) CR7420A (xx)
CY (1) CY1106273T1 (xx)
DE (1) DE60215224T2 (xx)
DK (1) DK1478373T3 (xx)
EA (1) EA007599B1 (xx)
EC (1) ECSP045305A (xx)
ES (1) ES2274107T3 (xx)
HK (1) HK1078780A1 (xx)
HU (1) HUP0402674A3 (xx)
IL (2) IL163579A0 (xx)
ME (1) MEP37208A (xx)
MX (1) MXPA04008185A (xx)
NO (1) NO20043932L (xx)
NZ (1) NZ534806A (xx)
PL (1) PL209558B1 (xx)
PT (1) PT1478373E (xx)
RS (1) RS50909B (xx)
UA (1) UA80965C2 (xx)
WO (1) WO2003070255A1 (xx)
ZA (1) ZA200407545B (xx)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005023301B4 (de) * 2005-05-13 2012-05-31 Bayer Schering Pharma Aktiengesellschaft Pharmazeutische Zusammensetzung enthaltend Gestagene und/oder Estrogene und 5-Methyl-(6S)-tetrahydrofolat
US20060293295A1 (en) * 2005-05-13 2006-12-28 Kai Strothmann Pharmaceutical composition comprising progestogens and/or estrogens and 5-methyl- (6S)-tetrahydrofolate
UY29527A1 (es) * 2005-05-13 2006-12-29 Schering Ag Composicinn farmaccutica que contienen gestrgenos y/o estrngenos y 5-metil - (6s) - tetrhidrofolato.
AU2012227235B2 (en) * 2005-05-13 2015-06-11 Bayer Intellectual Property Gmbh Pharmaceutical composition comprising progestogens and/or estrogens and 5-methyl-(6S)-tetrahydrofolate
EP1891959A1 (de) * 2006-08-14 2008-02-27 Bayer Schering Pharma Aktiengesellschaft Pharmazeutische Zusammensetzung zur Kontrazeption und zur Verminderung des Risikos angeborener Fehlbildungen
RU2009102443A (ru) * 2006-07-06 2010-08-20 Йенафарм ГмбХ унд Ко КГ (DE) Фармацевтический препарат для контрацепции и для предотвращения риска врожденных пороков развития
CN101489563A (zh) * 2006-07-06 2009-07-22 拜耳先灵医药股份有限公司 用于避孕和预防先天性畸形风险的药物制剂
US8617597B2 (en) 2006-07-06 2013-12-31 Bayer Intellectual Property Gmbh Pharmaceutical composition containing a tetrahydrofolic acid
AU2013202756B2 (en) * 2006-07-06 2015-06-04 Bayer Intellectual Property Gmbh Pharmaceutical composition containing a tetrahydrofolic acid
GB0715502D0 (en) * 2007-08-08 2007-09-19 Univ Manchester Methods
WO2009101021A2 (en) * 2008-02-13 2009-08-20 Bayer Schering Pharma Aktiengesellschaft Estradiol-containing drug delivery system
UY32836A (es) 2009-08-12 2011-03-31 Bayer Schering Pharma Ag Partículas estabilizadas que comprenden 5-metil-(6s)-tetrahidrofolato
PL2324832T5 (pl) * 2009-11-09 2017-10-31 Biogena Naturprodukte Gmbh & Co Kg Suplement diety przy przyjmowaniu hormonalnych środków antykoncepcyjnych
EA025511B1 (ru) 2011-06-01 2016-12-30 Эстетра С.П.Р.Л. Способ получения промежуточных соединений эстетрола
CN107266514A (zh) 2011-06-01 2017-10-20 埃斯特拉私人有限责任公司 用于产生雌四醇中间体的方法
EP2383279A1 (en) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Process for the preparation of estetrol
EP2773355B1 (en) * 2011-11-05 2022-06-08 South Alabama Medical Science Foundation Methods, formulations, and kits for rapidly repleting folate levels in women
HUE055562T2 (hu) 2011-11-23 2021-11-29 Therapeuticsmd Inc Természetes kombinációjú hormon helyettesítõ kiszerelések, és terápiák ezekkel
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
NZ720906A (en) * 2013-12-12 2022-04-29 Estetra Sprl Orally disintegrating solid dosage unit containing an estetrol component
RU2016143081A (ru) 2014-05-22 2018-06-26 Терапьютиксмд, Инк. Натуральные комбинированные гормонозаместительные составы и терапии
EP3310346B1 (en) 2015-06-18 2021-03-24 Estetra SPRL Orodispersible tablet containing estetrol
UA123098C2 (uk) 2015-06-18 2021-02-17 Естетра Спрл Диспергована у порожнині рота одиниця дозування, що містить естетрольний компонент
EA035687B1 (ru) * 2015-06-18 2020-07-27 Эстетра Спрл Диспергируемая в полости рта единица дозирования, содержащая эстетрольный компонент
DK3310345T3 (da) 2015-06-18 2021-05-25 Estetra Sprl Orodispersibel tablet indeholdende estetrol
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
KR20180126582A (ko) 2016-04-01 2018-11-27 쎄러퓨틱스엠디, 인코퍼레이티드 스테로이드 호르몬 약제학적 조성물
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
CA3178291A1 (en) 2016-08-05 2018-04-12 Estetra Srl Method for the management of dysmenorrhea and menstrual pain
JOP20200260A1 (ar) 2018-04-19 2019-10-19 Estetra Sprl مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

Family Cites Families (9)

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Publication number Priority date Publication date Assignee Title
JP3602141B2 (ja) * 1996-01-31 2004-12-15 サウス、アラバマ、メディカル、サイエンス、ファウンデーション 還元されたフォレートの天然異性体を含む食品およびビタミン製剤
CA2261764A1 (en) * 1996-07-30 1998-02-05 Jeffrey B. Blumberg Dietary supplements
WO1998011900A2 (en) * 1996-09-18 1998-03-26 Sarill William J Compositions containing cobalamin and amino acids
US6220453B1 (en) * 1998-04-07 2001-04-24 Fuji Photo Film Co., Ltd. Blood filter unit
US6190693B1 (en) * 1998-04-17 2001-02-20 Ortho-Mcneil Pharamceutical, Inc. Pharmaceutical methods of delivering folic acid
AU4573899A (en) * 1998-06-19 2000-01-05 Beth Israel Deaconess Medical Center Dietary supplement for post-menopausal women
US6479545B1 (en) * 1999-09-30 2002-11-12 Drugtech Corporation Formulation for menopausal women
DE10022510A1 (de) * 2000-05-10 2001-11-15 Basf Ag Zusammensetzungen enthaltend Folsäure und reduziertes Folat
BG104880A (en) * 2000-10-24 2002-04-30 Иван ХРИСТОВ Medicamentous preparation for multiple sclerosis treatment

Also Published As

Publication number Publication date
CN1620302A (zh) 2005-05-25
CA2476940A1 (en) 2003-08-28
BR0215613A (pt) 2004-12-07
EA200401014A1 (ru) 2006-10-27
ECSP045305A (es) 2004-10-26
EP1478373B1 (en) 2006-10-04
DE60215224D1 (de) 2006-11-16
ZA200407545B (en) 2006-06-28
CR7420A (es) 2006-02-06
DK1478373T3 (da) 2007-01-15
ATE341333T1 (de) 2006-10-15
NO20043932L (no) 2004-11-19
JP5037779B2 (ja) 2012-10-03
US20050164977A1 (en) 2005-07-28
CN1620302B (zh) 2011-04-27
PT1478373E (pt) 2007-01-31
AU2002343249A1 (en) 2003-09-09
MEP37208A (en) 2011-02-10
JP2005523283A (ja) 2005-08-04
PL209558B1 (pl) 2011-09-30
DE60215224T2 (de) 2007-08-23
RS50909B (sr) 2010-08-31
RS73304A (xx) 2007-02-05
NZ534806A (en) 2006-05-26
WO2003070255A1 (en) 2003-08-28
AU2002343249B2 (en) 2009-02-05
HUP0402674A3 (en) 2012-12-28
MXPA04008185A (es) 2004-11-26
EP1478373A1 (en) 2004-11-24
ES2274107T3 (es) 2007-05-16
EA007599B1 (ru) 2006-12-29
PL371441A1 (en) 2005-06-13
CA2476940C (en) 2011-11-01
UA80965C2 (en) 2007-11-26
KR20040094711A (ko) 2004-11-10
HUP0402674A2 (hu) 2005-04-28
IL163579A (en) 2011-03-31
CY1106273T1 (el) 2011-10-12
KR100936827B1 (ko) 2010-01-14
HK1078780A1 (en) 2006-03-24

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