IL161526A0 - Method for the recovery and purification of poxviruses from infected cells - Google Patents
Method for the recovery and purification of poxviruses from infected cellsInfo
- Publication number
- IL161526A0 IL161526A0 IL16152602A IL16152602A IL161526A0 IL 161526 A0 IL161526 A0 IL 161526A0 IL 16152602 A IL16152602 A IL 16152602A IL 16152602 A IL16152602 A IL 16152602A IL 161526 A0 IL161526 A0 IL 161526A0
- Authority
- IL
- Israel
- Prior art keywords
- infected cells
- poxviruses
- recovery
- virus
- purification
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000000746 purification Methods 0.000 title abstract 2
- 238000011084 recovery Methods 0.000 title abstract 2
- 241000700605 Viruses Species 0.000 abstract 4
- 241001183012 Modified Vaccinia Ankara virus Species 0.000 abstract 2
- 238000000265 homogenisation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/02—Recovery or purification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/275—Poxviridae, e.g. avipoxvirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24151—Methods of production or purification of viral material
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200101928 | 2001-12-20 | ||
| PCT/EP2002/014179 WO2003054175A1 (en) | 2001-12-20 | 2002-12-13 | Method for the recovery and purification of poxviruses from infected cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL161526A0 true IL161526A0 (en) | 2004-09-27 |
Family
ID=8160920
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16152602A IL161526A0 (en) | 2001-12-20 | 2002-12-13 | Method for the recovery and purification of poxviruses from infected cells |
| IL161526A IL161526A (en) | 2001-12-20 | 2004-04-20 | Method for the recovery and purification of poxviruses from infected cells, poxviruses isolated by said method and vaccines thereof |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL161526A IL161526A (en) | 2001-12-20 | 2004-04-20 | Method for the recovery and purification of poxviruses from infected cells, poxviruses isolated by said method and vaccines thereof |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US7056723B2 (xx) |
| EP (1) | EP1407006B9 (xx) |
| JP (2) | JP5322252B2 (xx) |
| KR (1) | KR100947976B1 (xx) |
| CN (1) | CN1289663C (xx) |
| AT (1) | ATE302268T1 (xx) |
| AU (1) | AU2002352247B2 (xx) |
| BR (1) | BRPI0215003B1 (xx) |
| CA (1) | CA2467099C (xx) |
| DE (1) | DE60205631T2 (xx) |
| DK (1) | DK1407006T3 (xx) |
| EA (1) | EA006485B1 (xx) |
| ES (1) | ES2247404T3 (xx) |
| HK (1) | HK1071765A1 (xx) |
| HU (1) | HU227507B1 (xx) |
| IL (2) | IL161526A0 (xx) |
| MX (1) | MXPA04006001A (xx) |
| NO (1) | NO335975B1 (xx) |
| NZ (1) | NZ533586A (xx) |
| PL (1) | PL205929B1 (xx) |
| SI (1) | SI1407006T1 (xx) |
| UA (1) | UA77735C2 (xx) |
| WO (1) | WO2003054175A1 (xx) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7445924B2 (en) | 2000-11-23 | 2008-11-04 | Bavarian Nordic A/S | Modified Vaccinia Ankara virus variant and cultivation method |
| NZ524661A (en) * | 2000-11-23 | 2005-03-24 | Bavarian Nordic As | Modified vaccinia ankara virus variant |
| KR101044538B1 (ko) | 2002-09-05 | 2011-06-27 | 버베리안 노딕 에이/에스 | 무혈청 조건하에서 일차세포의 배양 및 바이러스의 증식방법 |
| US7951576B2 (en) * | 2004-11-05 | 2011-05-31 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods for preparing cells and viruses |
| US7625570B1 (en) * | 2005-03-10 | 2009-12-01 | The Regents Of The University Of California | Methods for purifying adeno-associated virus |
| JP2010526546A (ja) * | 2007-05-14 | 2010-08-05 | バヴァリアン・ノルディック・アクティーゼルスカブ | ワクシニアウイルス系及び組換えワクシニアウイルス系ワクチンの精製 |
| US8003363B2 (en) | 2007-05-14 | 2011-08-23 | Bavarian Nordic A/S | Purification of vaccinia virus- and recombinant vaccinia virus-based vaccines |
| CN102257134B (zh) * | 2008-02-12 | 2014-03-05 | 赛诺菲巴斯德有限公司 | 使用离子交换和凝胶过滤色谱进行痘病毒纯化的方法 |
| CA2760465A1 (en) * | 2009-05-12 | 2010-11-18 | Transgene Sa | Method for orthopoxvirus production and purification |
| FR2953686B1 (fr) | 2009-12-14 | 2012-11-02 | Agronomique Inst Nat Rech | Procede pour reduire la teneur bacterienne d'un milieu alimentaire et/ou biologique d'interet, contenant des gouttelettes lipidiques |
| US10087423B2 (en) | 2010-07-20 | 2018-10-02 | Bavarian Nordic A/S | Method for harvesting expression products |
| CN102353792A (zh) * | 2011-07-07 | 2012-02-15 | 贵州大学 | 一种基于gpv p32蛋白的间接elisa试剂盒及制备方法 |
| FR3042121A1 (fr) | 2015-10-08 | 2017-04-14 | Jean-Marc Limacher | Composition anti-tumorale |
| US11306292B2 (en) | 2017-05-15 | 2022-04-19 | Janssen Vaccines & Prevention B.V. | Stable virus-containing composition |
| WO2018211419A1 (en) | 2017-05-15 | 2018-11-22 | Janssen Vaccines & Prevention B.V. | Stable virus-containing composition |
| AU2019336940A1 (en) | 2018-09-06 | 2021-03-11 | Bavarian Nordic A/S | Storage improved poxvirus compositions |
| WO2021180943A1 (en) | 2020-03-12 | 2021-09-16 | Bavarian Nordic A/S | Compositions improving poxvirus stability |
| WO2024003238A1 (en) | 2022-06-29 | 2024-01-04 | Bavarian Nordic A/S | Epstein-barr-virus vaccine |
| WO2024003239A1 (en) | 2022-06-29 | 2024-01-04 | Bavarian Nordic A/S | RECOMBINANT MODIFIED saRNA (VRP) AND VACCINIA VIRUS ANKARA (MVA) PRIME-BOOST REGIMEN |
| CN115197966A (zh) * | 2022-08-15 | 2022-10-18 | 深圳源兴基因技术有限公司 | 一种利用生物反应器大规模生产重组痘苗病毒载体的方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB877898A (en) | 1956-12-06 | 1961-09-20 | Apv Co Ltd | A new or improved method of liberating enzymes |
| JPS5328989B2 (xx) | 1974-05-27 | 1978-08-17 | ||
| CH621573A5 (en) | 1976-08-05 | 1981-02-13 | Vnii Biosinteza Belkovykh Vesc | Process for the continuous disintegration of microorganism cells and system for carrying out this process |
| JPS54154594A (en) | 1978-05-25 | 1979-12-05 | Sumitomo Chem Co Ltd | Extraction of glucose isomerase |
| WO1991001367A1 (en) | 1989-07-20 | 1991-02-07 | Bioeng, Inc. | Supercritical fluid disruption of and extraction from microbial cells |
| UA68327C2 (en) * | 1995-07-04 | 2004-08-16 | Gsf Forschungszentrum Fur Unwe | A recombinant mva virus, an isolated eukaryotic cell, infected with recombinant mva virus, a method for production in vitro of polypeptides with use of said cell, a method for production in vitro of virus parts (variants), vaccine containing the recombinant mva virus, a method for immunization of animals |
| TW426733B (en) | 1995-10-06 | 2001-03-21 | Merck & Co Inc | Method of disrupting cultured cells using an impinging jet device |
| AU4556597A (en) * | 1996-09-24 | 1998-04-17 | Bavarian Nordic Research Institute A/S | Recombinant mva virus expressing dengue virus antigens, and the use thereof in vaccines |
| US5721120A (en) | 1996-10-02 | 1998-02-24 | Merck & Co., Inc. | Method of disrupting cultured cells using an impinging jet device |
| NZ299720A (en) * | 1996-11-08 | 1999-07-29 | Howick Engineering Ltd | Epicyclic input/output annuli of same pcd, with planetary input/output gear sets, and with only one set having aligned teeth |
| EP0968284B1 (en) * | 1996-11-20 | 2006-12-13 | Introgen Therapeutics, Inc. | An improved method for the production and purification of adenoviral vectors |
| US6000551A (en) | 1996-12-20 | 1999-12-14 | Eastman Chemical Company | Method for rupturing microalgae cells |
| FR2787465A1 (fr) * | 1998-12-21 | 2000-06-23 | Transgene Sa | Procede d'inactivation des virus enveloppes dans une preparation virale de virus non enveloppes |
| EP1155120B1 (fr) * | 1999-02-22 | 2006-07-05 | Transgene S.A. | Procede d'obtention d'une preparation virale purifiee |
| DE19918619A1 (de) | 1999-04-23 | 2000-10-26 | Rhein Biotech Proz & Prod Gmbh | Verfahren zum Gewinnen von rekombinantem HBsAg |
| US6951752B2 (en) * | 2001-12-10 | 2005-10-04 | Bexter Healthcare S.A. | Method for large scale production of virus antigen |
-
2002
- 2002-12-13 NZ NZ533586A patent/NZ533586A/en not_active IP Right Cessation
- 2002-12-13 CN CNB028255267A patent/CN1289663C/zh not_active Expired - Fee Related
- 2002-12-13 JP JP2003554879A patent/JP5322252B2/ja not_active Expired - Fee Related
- 2002-12-13 HU HU0402337A patent/HU227507B1/hu not_active IP Right Cessation
- 2002-12-13 US US10/495,151 patent/US7056723B2/en not_active Expired - Lifetime
- 2002-12-13 MX MXPA04006001A patent/MXPA04006001A/es active IP Right Grant
- 2002-12-13 SI SI200230220T patent/SI1407006T1/sl unknown
- 2002-12-13 DE DE60205631T patent/DE60205631T2/de not_active Expired - Lifetime
- 2002-12-13 EA EA200400833A patent/EA006485B1/ru not_active IP Right Cessation
- 2002-12-13 EP EP02787945A patent/EP1407006B9/en not_active Expired - Lifetime
- 2002-12-13 PL PL369498A patent/PL205929B1/pl unknown
- 2002-12-13 ES ES02787945T patent/ES2247404T3/es not_active Expired - Lifetime
- 2002-12-13 CA CA2467099A patent/CA2467099C/en not_active Expired - Fee Related
- 2002-12-13 DK DK02787945T patent/DK1407006T3/da active
- 2002-12-13 AU AU2002352247A patent/AU2002352247B2/en not_active Ceased
- 2002-12-13 BR BRPI0215003A patent/BRPI0215003B1/pt not_active IP Right Cessation
- 2002-12-13 IL IL16152602A patent/IL161526A0/xx unknown
- 2002-12-13 UA UA20040705906A patent/UA77735C2/uk unknown
- 2002-12-13 KR KR1020047009777A patent/KR100947976B1/ko active IP Right Grant
- 2002-12-13 WO PCT/EP2002/014179 patent/WO2003054175A1/en active IP Right Grant
- 2002-12-13 AT AT02787945T patent/ATE302268T1/de active
-
2004
- 2004-04-20 IL IL161526A patent/IL161526A/en not_active IP Right Cessation
- 2004-07-19 NO NO20043181A patent/NO335975B1/no not_active IP Right Cessation
-
2005
- 2005-05-26 HK HK05104416A patent/HK1071765A1/xx not_active IP Right Cessation
-
2009
- 2009-11-19 JP JP2009263687A patent/JP2010046093A/ja active Pending
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