DK1407006T3 - Fremgangsmåde til indvinding og oprensning af poxvirus fra inficerede celler - Google Patents
Fremgangsmåde til indvinding og oprensning af poxvirus fra inficerede cellerInfo
- Publication number
- DK1407006T3 DK1407006T3 DK02787945T DK02787945T DK1407006T3 DK 1407006 T3 DK1407006 T3 DK 1407006T3 DK 02787945 T DK02787945 T DK 02787945T DK 02787945 T DK02787945 T DK 02787945T DK 1407006 T3 DK1407006 T3 DK 1407006T3
- Authority
- DK
- Denmark
- Prior art keywords
- infected cells
- recovery
- virus
- purification
- pox virus
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 238000000746 purification Methods 0.000 title abstract 2
- 238000011084 recovery Methods 0.000 title abstract 2
- 241001183012 Modified Vaccinia Ankara virus Species 0.000 abstract 2
- 238000000265 homogenisation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/02—Recovery or purification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/275—Poxviridae, e.g. avipoxvirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24151—Methods of production or purification of viral material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Compounds Of Unknown Constitution (AREA)
- Meat, Egg Or Seafood Products (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200101928 | 2001-12-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1407006T3 true DK1407006T3 (da) | 2005-12-12 |
Family
ID=8160920
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02787945T DK1407006T3 (da) | 2001-12-20 | 2002-12-13 | Fremgangsmåde til indvinding og oprensning af poxvirus fra inficerede celler |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US7056723B2 (da) |
| EP (1) | EP1407006B9 (da) |
| JP (2) | JP5322252B2 (da) |
| KR (1) | KR100947976B1 (da) |
| CN (1) | CN1289663C (da) |
| AT (1) | ATE302268T1 (da) |
| AU (1) | AU2002352247B2 (da) |
| BR (1) | BRPI0215003B1 (da) |
| CA (1) | CA2467099C (da) |
| DE (1) | DE60205631T2 (da) |
| DK (1) | DK1407006T3 (da) |
| EA (1) | EA006485B1 (da) |
| ES (1) | ES2247404T3 (da) |
| HK (1) | HK1071765A1 (da) |
| HU (1) | HU227507B1 (da) |
| IL (2) | IL161526A0 (da) |
| MX (1) | MXPA04006001A (da) |
| NO (1) | NO335975B1 (da) |
| NZ (1) | NZ533586A (da) |
| PL (1) | PL205929B1 (da) |
| SI (1) | SI1407006T1 (da) |
| UA (1) | UA77735C2 (da) |
| WO (1) | WO2003054175A1 (da) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EE05680B1 (et) * | 2000-11-23 | 2013-10-15 | Bavarian Nordic A/S | Muundatud vaktsiiniaviirus, selle valmistamine ja kasutamine, seda sisaldav farmatseutiline kompositsioon ning vaktsiin |
| US7445924B2 (en) | 2000-11-23 | 2008-11-04 | Bavarian Nordic A/S | Modified Vaccinia Ankara virus variant and cultivation method |
| EA009008B1 (ru) * | 2002-09-05 | 2007-10-26 | Бавариан Нордик А/С | Способ амплификации вируса оспы |
| EP1807508A4 (en) * | 2004-11-05 | 2008-03-12 | Us Gov Health & Human Serv | METHODS FOR PREPARING CELLS AND VIRUSES |
| US7625570B1 (en) * | 2005-03-10 | 2009-12-01 | The Regents Of The University Of California | Methods for purifying adeno-associated virus |
| JP2010526546A (ja) * | 2007-05-14 | 2010-08-05 | バヴァリアン・ノルディック・アクティーゼルスカブ | ワクシニアウイルス系及び組換えワクシニアウイルス系ワクチンの精製 |
| US8003363B2 (en) | 2007-05-14 | 2011-08-23 | Bavarian Nordic A/S | Purification of vaccinia virus- and recombinant vaccinia virus-based vaccines |
| BRPI0908474A2 (pt) * | 2008-02-12 | 2016-07-26 | Sanofi Pasteur Ltd | métodos de uso de cromatografia de troca de íon e de filtração de gel para purificação de vírus causador da catapora |
| JP5855564B2 (ja) * | 2009-05-12 | 2016-02-09 | トランジェーヌ、ソシエテ、アノニムＴｒａｎｓｇｅｎｅ Ｓ．Ａ． | オルソポックスウイルスの製造および精製方法 |
| FR2953686B1 (fr) * | 2009-12-14 | 2012-11-02 | Agronomique Inst Nat Rech | Procede pour reduire la teneur bacterienne d'un milieu alimentaire et/ou biologique d'interet, contenant des gouttelettes lipidiques |
| AU2011281982B2 (en) | 2010-07-20 | 2015-12-17 | Bavarian Nordic A/S | Method for harvesting expression products |
| CN102353792A (zh) * | 2011-07-07 | 2012-02-15 | 贵州大学 | 一种基于gpv p32蛋白的间接elisa试剂盒及制备方法 |
| FR3042121A1 (fr) | 2015-10-08 | 2017-04-14 | Jean-Marc Limacher | Composition anti-tumorale |
| JP2020519666A (ja) | 2017-05-15 | 2020-07-02 | ヤンセン ファッシンズ アンド プリベンション ベーフェーＪａｎｓｓｅｎ Ｖａｃｃｉｎｅｓ ＆ Ｐｒｅｖｅｎｔｉｏｎ Ｂ．Ｖ． | 安定性のウイルス含有組成物 |
| EP3624845A1 (en) | 2017-05-15 | 2020-03-25 | Janssen Vaccines & Prevention B.V. | Stable virus-containing composition |
| US20210187100A1 (en) | 2018-09-06 | 2021-06-24 | Bavarian Nordic A/S | Storage Improved Poxvirus Compositions |
| CN115243717A (zh) | 2020-03-12 | 2022-10-25 | 巴法里安诺迪克有限公司 | 改善痘病毒稳定性的组合物 |
| WO2024003238A1 (en) | 2022-06-29 | 2024-01-04 | Bavarian Nordic A/S | Epstein-barr-virus vaccine |
| WO2024003239A1 (en) | 2022-06-29 | 2024-01-04 | Bavarian Nordic A/S | RECOMBINANT MODIFIED saRNA (VRP) AND VACCINIA VIRUS ANKARA (MVA) PRIME-BOOST REGIMEN |
| CN115197966A (zh) * | 2022-08-15 | 2022-10-18 | 深圳源兴基因技术有限公司 | 一种利用生物反应器大规模生产重组痘苗病毒载体的方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB877898A (en) | 1956-12-06 | 1961-09-20 | Apv Co Ltd | A new or improved method of liberating enzymes |
| JPS5328989B2 (da) | 1974-05-27 | 1978-08-17 | ||
| CH621573A5 (en) | 1976-08-05 | 1981-02-13 | Vnii Biosinteza Belkovykh Vesc | Process for the continuous disintegration of microorganism cells and system for carrying out this process |
| JPS54154594A (en) | 1978-05-25 | 1979-12-05 | Sumitomo Chem Co Ltd | Extraction of glucose isomerase |
| WO1991001367A1 (en) | 1989-07-20 | 1991-02-07 | Bioeng, Inc. | Supercritical fluid disruption of and extraction from microbial cells |
| UA68327C2 (en) * | 1995-07-04 | 2004-08-16 | Gsf Forschungszentrum Fur Unwe | A recombinant mva virus, an isolated eukaryotic cell, infected with recombinant mva virus, a method for production in vitro of polypeptides with use of said cell, a method for production in vitro of virus parts (variants), vaccine containing the recombinant mva virus, a method for immunization of animals |
| TW426733B (en) | 1995-10-06 | 2001-03-21 | Merck & Co Inc | Method of disrupting cultured cells using an impinging jet device |
| EP0951555A2 (en) | 1996-09-24 | 1999-10-27 | Bavarian Nordic Research Institute A/S | Recombinant mva virus expressing dengue virus antigens, and the use thereof in vaccines |
| US5721120A (en) | 1996-10-02 | 1998-02-24 | Merck & Co., Inc. | Method of disrupting cultured cells using an impinging jet device |
| NZ299720A (en) * | 1996-11-08 | 1999-07-29 | Howick Engineering Ltd | Epicyclic input/output annuli of same pcd, with planetary input/output gear sets, and with only one set having aligned teeth |
| ATE348155T1 (de) * | 1996-11-20 | 2007-01-15 | Introgen Therapeutics Inc | Ein verbessertes verfahren zur produktion und reinigung von adenoviralen vektoren |
| US6000551A (en) | 1996-12-20 | 1999-12-14 | Eastman Chemical Company | Method for rupturing microalgae cells |
| FR2787465A1 (fr) * | 1998-12-21 | 2000-06-23 | Transgene Sa | Procede d'inactivation des virus enveloppes dans une preparation virale de virus non enveloppes |
| DE60029195T2 (de) * | 1999-02-22 | 2007-06-28 | Transgene S.A. | Verfahren zur Gewinnung von purifizierter Virenzusammensetzung |
| DE19918619A1 (de) | 1999-04-23 | 2000-10-26 | Rhein Biotech Proz & Prod Gmbh | Verfahren zum Gewinnen von rekombinantem HBsAg |
| US6951752B2 (en) * | 2001-12-10 | 2005-10-04 | Bexter Healthcare S.A. | Method for large scale production of virus antigen |
-
2002
- 2002-12-13 UA UA20040705906A patent/UA77735C2/uk unknown
- 2002-12-13 AU AU2002352247A patent/AU2002352247B2/en not_active Ceased
- 2002-12-13 MX MXPA04006001A patent/MXPA04006001A/es active IP Right Grant
- 2002-12-13 SI SI200230220T patent/SI1407006T1/sl unknown
- 2002-12-13 DK DK02787945T patent/DK1407006T3/da active
- 2002-12-13 ES ES02787945T patent/ES2247404T3/es not_active Expired - Lifetime
- 2002-12-13 EP EP02787945A patent/EP1407006B9/en not_active Expired - Lifetime
- 2002-12-13 AT AT02787945T patent/ATE302268T1/de active
- 2002-12-13 EA EA200400833A patent/EA006485B1/ru not_active IP Right Cessation
- 2002-12-13 CN CNB028255267A patent/CN1289663C/zh not_active Expired - Fee Related
- 2002-12-13 US US10/495,151 patent/US7056723B2/en not_active Expired - Lifetime
- 2002-12-13 JP JP2003554879A patent/JP5322252B2/ja not_active Expired - Fee Related
- 2002-12-13 WO PCT/EP2002/014179 patent/WO2003054175A1/en active IP Right Grant
- 2002-12-13 KR KR1020047009777A patent/KR100947976B1/ko active IP Right Grant
- 2002-12-13 BR BRPI0215003A patent/BRPI0215003B1/pt not_active IP Right Cessation
- 2002-12-13 CA CA2467099A patent/CA2467099C/en not_active Expired - Fee Related
- 2002-12-13 DE DE60205631T patent/DE60205631T2/de not_active Expired - Lifetime
- 2002-12-13 IL IL16152602A patent/IL161526A0/xx unknown
- 2002-12-13 NZ NZ533586A patent/NZ533586A/en not_active IP Right Cessation
- 2002-12-13 HU HU0402337A patent/HU227507B1/hu not_active IP Right Cessation
- 2002-12-13 PL PL369498A patent/PL205929B1/pl unknown
-
2004
- 2004-04-20 IL IL161526A patent/IL161526A/en not_active IP Right Cessation
- 2004-07-19 NO NO20043181A patent/NO335975B1/no not_active IP Right Cessation
-
2005
- 2005-05-26 HK HK05104416A patent/HK1071765A1/xx not_active IP Right Cessation
-
2009
- 2009-11-19 JP JP2009263687A patent/JP2010046093A/ja active Pending
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