IL160367A0 - Pyrrolo pyrimidines as agents for the inhibition of cystein proteases - Google Patents

Pyrrolo pyrimidines as agents for the inhibition of cystein proteases

Info

Publication number
IL160367A0
IL160367A0 IL16036702A IL16036702A IL160367A0 IL 160367 A0 IL160367 A0 IL 160367A0 IL 16036702 A IL16036702 A IL 16036702A IL 16036702 A IL16036702 A IL 16036702A IL 160367 A0 IL160367 A0 IL 160367A0
Authority
IL
Israel
Prior art keywords
inhibition
agents
cystein proteases
pyrimidines
pyrrolo
Prior art date
Application number
IL16036702A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL160367A0 publication Critical patent/IL160367A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL16036702A 2001-08-30 2002-08-29 Pyrrolo pyrimidines as agents for the inhibition of cystein proteases IL160367A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0121033.5A GB0121033D0 (en) 2001-08-30 2001-08-30 Organic compounds
PCT/EP2002/009663 WO2003020721A1 (en) 2001-08-30 2002-08-29 Pyrrolo pyrimidines as agents for the inhibition of cystein proteases

Publications (1)

Publication Number Publication Date
IL160367A0 true IL160367A0 (en) 2004-07-25

Family

ID=9921234

Family Applications (3)

Application Number Title Priority Date Filing Date
IL16036702A IL160367A0 (en) 2001-08-30 2002-08-29 Pyrrolo pyrimidines as agents for the inhibition of cystein proteases
IL160367A IL160367A (en) 2001-08-30 2004-02-12 Pyrrolo pyrimidines as agents for the inhibition of cysteine proteases
IL198643A IL198643A (en) 2001-08-30 2009-05-07 Pyrrolo pyrimidines as agents for the inhibition of cystein proteases

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL160367A IL160367A (en) 2001-08-30 2004-02-12 Pyrrolo pyrimidines as agents for the inhibition of cysteine proteases
IL198643A IL198643A (en) 2001-08-30 2009-05-07 Pyrrolo pyrimidines as agents for the inhibition of cystein proteases

Country Status (30)

Country Link
US (2) US7452886B2 (es)
EP (1) EP1423391B8 (es)
JP (1) JP4629334B2 (es)
KR (1) KR100695845B1 (es)
CN (1) CN100372849C (es)
AR (1) AR036374A1 (es)
AT (1) ATE326469T1 (es)
AU (1) AU2002333760B2 (es)
BR (1) BR0212226A (es)
CA (1) CA2458684C (es)
CY (1) CY1105573T1 (es)
DE (1) DE60211530T2 (es)
DK (1) DK1423391T3 (es)
EC (1) ECSP044998A (es)
ES (1) ES2262888T3 (es)
GB (1) GB0121033D0 (es)
HK (1) HK1072254A1 (es)
HU (1) HUP0401301A3 (es)
IL (3) IL160367A0 (es)
MX (1) MXPA04001935A (es)
MY (1) MY157368A (es)
NO (1) NO328890B1 (es)
NZ (1) NZ531343A (es)
PE (1) PE20030418A1 (es)
PL (1) PL368280A1 (es)
PT (1) PT1423391E (es)
RU (1) RU2331644C2 (es)
TW (1) TWI297690B (es)
WO (1) WO2003020721A1 (es)
ZA (1) ZA200401042B (es)

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AU2004233582B2 (en) * 2003-04-28 2008-05-15 Novartis Ag Pharmaceutical compositon comprising a cathepsin S inhibitor and an opioid
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Also Published As

Publication number Publication date
CA2458684C (en) 2009-04-07
PT1423391E (pt) 2006-09-29
KR100695845B1 (ko) 2007-03-20
AR036374A1 (es) 2004-09-01
MY157368A (en) 2016-06-15
HUP0401301A2 (hu) 2004-10-28
NO328890B1 (no) 2010-06-07
NZ531343A (en) 2006-01-27
RU2004109815A (ru) 2005-10-20
PL368280A1 (en) 2005-03-21
GB0121033D0 (en) 2001-10-24
AU2002333760B2 (en) 2007-01-04
JP4629334B2 (ja) 2011-02-09
HUP0401301A3 (en) 2008-03-28
ZA200401042B (en) 2004-10-25
IL160367A (en) 2009-12-24
IL198643A (en) 2010-12-30
WO2003020721A1 (en) 2003-03-13
EP1423391B8 (en) 2007-12-12
US20050054851A1 (en) 2005-03-10
DK1423391T3 (da) 2006-09-25
CY1105573T1 (el) 2010-07-28
CN100372849C (zh) 2008-03-05
CA2458684A1 (en) 2003-03-13
MXPA04001935A (es) 2004-06-15
US20090054467A1 (en) 2009-02-26
HK1072254A1 (en) 2005-08-19
ES2262888T3 (es) 2006-12-01
ATE326469T1 (de) 2006-06-15
CN1549817A (zh) 2004-11-24
PE20030418A1 (es) 2003-06-12
RU2331644C2 (ru) 2008-08-20
BR0212226A (pt) 2004-08-17
NO20041180L (no) 2004-03-19
EP1423391A1 (en) 2004-06-02
KR20040029123A (ko) 2004-04-03
JP2005502683A (ja) 2005-01-27
US7452886B2 (en) 2008-11-18
EP1423391B1 (en) 2006-05-17
DE60211530T2 (de) 2006-12-21
TWI297690B (en) 2008-06-11
ECSP044998A (es) 2004-04-28
DE60211530D1 (de) 2006-06-22

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