IL155799A - Pharmaceutical preparations of thizoxanide and nitazoxanide - Google Patents

Pharmaceutical preparations of thizoxanide and nitazoxanide

Info

Publication number
IL155799A
IL155799A IL15579998A IL15579998A IL155799A IL 155799 A IL155799 A IL 155799A IL 15579998 A IL15579998 A IL 15579998A IL 15579998 A IL15579998 A IL 15579998A IL 155799 A IL155799 A IL 155799A
Authority
IL
Israel
Prior art keywords
acid
composition
formula
active
compound
Prior art date
Application number
IL15579998A
Other languages
English (en)
Hebrew (he)
Other versions
IL155799A0 (en
Original Assignee
Romark Lab Lc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27420362&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL155799(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/852,447 external-priority patent/US5968961A/en
Priority claimed from US08/887,809 external-priority patent/US5965590A/en
Priority claimed from US08/887,810 external-priority patent/US5856348A/en
Application filed by Romark Lab Lc filed Critical Romark Lab Lc
Publication of IL155799A0 publication Critical patent/IL155799A0/xx
Publication of IL155799A publication Critical patent/IL155799A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A61P33/12—Schistosomicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL15579998A 1997-05-07 1998-05-06 Pharmaceutical preparations of thizoxanide and nitazoxanide IL155799A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/852,447 US5968961A (en) 1997-05-07 1997-05-07 Pharmaceutical compositions of tizoxanide and nitazoxanide
US08/887,809 US5965590A (en) 1994-09-08 1997-07-03 Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide
US08/887,810 US5856348A (en) 1994-09-08 1997-07-03 Method for treatment of trematodes with pharmaceutical compositions of tizoxanide and nitazoxanide
PCT/US1998/009229 WO1998050035A1 (en) 1997-05-07 1998-05-06 Pharmaceutical compositions of tizoxanide and nitazoxanide
IL13251698A IL132516A (en) 1997-05-07 1998-05-06 Pharmaceutical compositions of tizoxanide and nitazoxanide

Publications (2)

Publication Number Publication Date
IL155799A0 IL155799A0 (en) 2003-12-23
IL155799A true IL155799A (en) 2004-08-31

Family

ID=27420362

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15579998A IL155799A (en) 1997-05-07 1998-05-06 Pharmaceutical preparations of thizoxanide and nitazoxanide
IL13251698A IL132516A (en) 1997-05-07 1998-05-06 Pharmaceutical compositions of tizoxanide and nitazoxanide

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL13251698A IL132516A (en) 1997-05-07 1998-05-06 Pharmaceutical compositions of tizoxanide and nitazoxanide

Country Status (35)

Country Link
EP (2) EP1005342B1 (zh)
JP (1) JP3739802B2 (zh)
KR (2) KR100426657B1 (zh)
CN (2) CN100515420C (zh)
AP (1) AP1103A (zh)
AR (1) AR057242A2 (zh)
AT (2) ATE228839T1 (zh)
AU (1) AU740022B2 (zh)
BG (2) BG109365A (zh)
BR (1) BR9808722A (zh)
CA (2) CA2418634C (zh)
CZ (2) CZ298270B6 (zh)
DE (2) DE69809928T2 (zh)
DK (2) DK1005342T3 (zh)
EA (2) EA002920B1 (zh)
EE (1) EE04870B1 (zh)
ES (2) ES2232687T3 (zh)
GE (1) GEP20032970B (zh)
HK (1) HK1025907A1 (zh)
HU (1) HU229641B1 (zh)
IL (2) IL155799A (zh)
IS (1) IS2087B (zh)
LV (1) LV12492B (zh)
ME (1) ME00530B (zh)
NO (2) NO313983B1 (zh)
NZ (2) NZ513881A (zh)
OA (1) OA11169A (zh)
PL (1) PL193275B1 (zh)
PT (2) PT1005342E (zh)
RO (1) RO120605B1 (zh)
SI (1) SI20149B (zh)
SK (2) SK283947B6 (zh)
TR (1) TR199902733T2 (zh)
UA (2) UA57079C2 (zh)
WO (1) WO1998050035A1 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2467321A1 (en) 2004-05-14 2005-11-14 Paul J. Santerre Polymeric coupling agents and pharmaceutically-active polymers made therefrom
DK1976516T3 (da) * 2006-01-09 2013-07-15 Romark Lab Lc Behandling af viral hepatitis
CA2752233C (en) * 2009-02-13 2017-01-03 Romark Laboratories L.C. Controlled release pharmaceutical formulations of nitazoxanide
CN105853415A (zh) 2009-05-12 2016-08-17 罗马克实验室有限公司 卤代烷基杂芳基苯甲酰胺化合物
KR20170141830A (ko) 2009-06-26 2017-12-26 로마크 레버러토리즈, 엘.씨. 인플루엔자를 치료하기 위한 화합물 및 방법
WO2013110975A1 (es) 2012-01-27 2013-08-01 Siegfried Rhein S.A. De C.V. Composición de nitazoxanida mejorada y proceso para prepararla
CA2967333A1 (en) * 2014-11-11 2016-05-19 Romark Laboratories, L.C. Compositions and methods of treatment with prodrugs of tizoxanide, an analogue or salt thereof
CA3087898A1 (en) 2018-02-02 2019-08-08 Ripple Therapeutics Corporation Glass formulations comprising steroid dimers and uses thereof
CA3176134A1 (en) 2020-05-01 2021-11-04 Ripple Therapeutics Corporation Heterodimer compositions and methods for the treatment of ocular disorders
WO2022130406A1 (en) * 2020-12-15 2022-06-23 Cipla Limited Inhalation composition of nitazoxanide or its derivatives for use in coronavirus disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1437800A (en) * 1973-08-08 1976-06-03 Phavic Sprl Derivatives of 2-benzamido-5-nitro-thiazoles
US4315018A (en) * 1978-12-07 1982-02-09 Rossignol Jean F Specific parasiticidal use of 2-benzamido-5-nitro-thiazole derivatives
US5387598A (en) * 1994-04-13 1995-02-07 Rossignol; Jean-Francois Composition and galenic formulation suitable for combatting affections of the lower abdomen
US5578621A (en) * 1994-09-08 1996-11-26 Romark Lab Lc Benzamide derivatives

Also Published As

Publication number Publication date
DK1005342T3 (da) 2003-03-24
AP9901675A0 (en) 1999-12-31
CA2418634C (en) 2004-10-26
CN100515420C (zh) 2009-07-22
KR100576646B1 (ko) 2006-05-08
CN1255060A (zh) 2000-05-31
LV12492B (en) 2001-01-20
AU740022B2 (en) 2001-10-25
IL132516A (en) 2003-12-10
EE9900578A (et) 2000-08-15
EA199901012A1 (ru) 2000-08-28
PL193275B1 (pl) 2007-01-31
CA2288003A1 (en) 1998-11-12
SK283947B6 (sk) 2004-05-04
HUP0003330A2 (hu) 2001-05-28
SK151199A3 (en) 2000-07-11
IL132516A0 (en) 2001-03-19
UA57079C2 (uk) 2003-06-16
CZ298269B6 (cs) 2007-08-08
TR199902733T2 (xx) 2000-03-21
CA2418634A1 (en) 1998-11-12
EP1222921A1 (en) 2002-07-17
EA002920B1 (ru) 2002-10-31
JP2001503067A (ja) 2001-03-06
HU229641B1 (en) 2014-03-28
CN1552322A (zh) 2004-12-08
NO20021832L (no) 2000-01-04
PT1222921E (pt) 2005-02-28
DE69809928T2 (de) 2003-04-24
AR057242A2 (es) 2007-11-21
IS2087B (is) 2006-03-15
AP1103A (en) 2002-09-04
ES2232687T3 (es) 2005-06-01
ATE228839T1 (de) 2002-12-15
NO20021832D0 (no) 2002-04-18
OA11169A (en) 2003-04-25
ES2150404T3 (es) 2003-07-01
DK1222921T3 (da) 2005-03-07
WO1998050035A1 (en) 1998-11-12
CZ298270B6 (cs) 2007-08-08
IL155799A0 (en) 2003-12-23
KR20010020322A (ko) 2001-03-15
EP1005342B1 (en) 2002-12-04
RO120605B1 (ro) 2006-05-30
PT1005342E (pt) 2003-02-28
JP3739802B2 (ja) 2006-01-25
ATE281166T1 (de) 2004-11-15
BG103958A (en) 2000-07-31
PL336805A1 (en) 2000-07-17
EP1005342A1 (en) 2000-06-07
NO995406D0 (no) 1999-11-04
EE04870B1 (et) 2007-08-15
IS5223A (is) 1999-10-19
DE69809928D1 (de) 2003-01-16
NZ513881A (en) 2002-10-25
EA002908B1 (ru) 2002-10-31
GEP20032970B (en) 2003-05-27
NZ500149A (en) 2001-11-30
DE69827417T2 (de) 2005-10-27
DE69827417D1 (de) 2004-12-09
BR9808722A (pt) 2000-07-11
CA2288003C (en) 2003-10-21
NO335781B1 (no) 2015-02-16
CN1158074C (zh) 2004-07-21
ME00530B (me) 2011-10-10
SI20149A (sl) 2000-08-31
EP1222921B1 (en) 2004-11-03
ES2150404T1 (es) 2000-12-01
KR100426657B1 (ko) 2004-04-13
EP1005342A4 (en) 2001-02-07
AU7289598A (en) 1998-11-27
SK283946B6 (sk) 2004-05-04
SI20149B (en) 2001-08-31
BG109365A (en) 2006-08-31
NO995406L (no) 2000-01-04
HUP0003330A3 (en) 2002-10-28
BG64973B1 (bg) 2006-11-30
NO313983B1 (no) 2003-01-13
HK1025907A1 (en) 2000-12-01
UA74388C2 (uk) 2005-12-15
EA200100956A1 (ru) 2002-02-28
LV12492A (en) 2000-06-20
KR20040004544A (ko) 2004-01-13
CZ391199A3 (cs) 2000-07-12

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Legal Events

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KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees