IL154326A0 - Anti-dual integrin antibodies, compositions, methods and uses - Google Patents
Anti-dual integrin antibodies, compositions, methods and usesInfo
- Publication number
- IL154326A0 IL154326A0 IL15432601A IL15432601A IL154326A0 IL 154326 A0 IL154326 A0 IL 154326A0 IL 15432601 A IL15432601 A IL 15432601A IL 15432601 A IL15432601 A IL 15432601A IL 154326 A0 IL154326 A0 IL 154326A0
- Authority
- IL
- Israel
- Prior art keywords
- compositions
- methods
- integrin antibodies
- dual integrin
- beta
- Prior art date
Links
- 102000006495 integrins Human genes 0.000 title abstract 2
- 108010044426 integrins Proteins 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5029—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on cell motility
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/01—Animal expressing industrially exogenous proteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70546—Integrin superfamily, e.g. VLAs, leuCAM, GPIIb/GPIIIa, LPAM
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Neurology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Neurosurgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Diabetes (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22336300P | 2000-08-07 | 2000-08-07 | |
US09/920,267 US7288390B2 (en) | 2000-08-07 | 2001-08-01 | Anti-dual integrin antibodies, compositions, methods and uses |
PCT/US2001/024784 WO2002012501A2 (en) | 2000-08-07 | 2001-08-07 | Anti-dual integrin antibodies, compositions, methods and uses |
Publications (1)
Publication Number | Publication Date |
---|---|
IL154326A0 true IL154326A0 (en) | 2003-09-17 |
Family
ID=26917697
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15432601A IL154326A0 (en) | 2000-08-07 | 2001-08-07 | Anti-dual integrin antibodies, compositions, methods and uses |
Country Status (23)
Country | Link |
---|---|
US (1) | US7288390B2 (sr) |
EP (2) | EP1309693B1 (sr) |
JP (1) | JP5014557B2 (sr) |
KR (1) | KR100832486B1 (sr) |
CN (1) | CN1468307B (sr) |
AT (1) | ATE470714T1 (sr) |
AU (1) | AU8316701A (sr) |
BR (1) | BR0113112A (sr) |
CA (1) | CA2418962C (sr) |
DE (1) | DE60142342D1 (sr) |
DK (1) | DK1309693T3 (sr) |
EA (1) | EA007617B1 (sr) |
ES (1) | ES2346041T3 (sr) |
HR (1) | HRP20030088B1 (sr) |
HU (1) | HU229418B1 (sr) |
IL (1) | IL154326A0 (sr) |
MX (1) | MXPA03001230A (sr) |
NO (1) | NO334999B1 (sr) |
NZ (1) | NZ524146A (sr) |
PL (1) | PL213030B1 (sr) |
PT (1) | PT1309693E (sr) |
RS (1) | RS51197B (sr) |
WO (1) | WO2002012501A2 (sr) |
Families Citing this family (77)
Publication number | Priority date | Publication date | Assignee | Title |
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US20030059427A1 (en) * | 2000-04-28 | 2003-03-27 | Force Walker R. | Isolation and characterization of highly active anti-CD40 antibody |
US7163681B2 (en) * | 2000-08-07 | 2007-01-16 | Centocor, Inc. | Anti-integrin antibodies, compositions, methods and uses |
US8703126B2 (en) | 2000-10-12 | 2014-04-22 | Genentech, Inc. | Reduced-viscosity concentrated protein formulations |
PT1391464E (pt) | 2001-04-27 | 2007-11-15 | Kirin Pharma Kk | Anticorpo monoclonal anti-cd40 |
US7829087B2 (en) * | 2001-07-09 | 2010-11-09 | Elan Pharmaceuticals, Inc. | Methods of treating cognitive impairment |
CA2453403C (en) * | 2001-07-09 | 2013-10-08 | Elan Pharmaceuticals, Inc. | Methods of inhibiting amyloid toxicity |
ME00804B (me) | 2002-03-13 | 2012-03-20 | Biogen Idec Inc | Anti-alpha v beta 6 antitela |
AR042145A1 (es) * | 2002-11-27 | 2005-06-08 | Dow Agrociences Llc | Produccion de inmunoglobulinas en plantas con una fucocilacion reducida |
KR20050110628A (ko) * | 2003-02-10 | 2005-11-23 | 엘란 파마슈티칼스, 인크. | 면역글로불린 제제 및 이의 제조방법 |
EP1599502A1 (en) * | 2003-02-27 | 2005-11-30 | TheraVision GmbH | A molecule which binds cd80 and cd86 |
ZA200507757B (en) | 2003-04-04 | 2007-01-31 | Genentech Inc | High concentration antibody and protein formulations |
US9708410B2 (en) | 2003-05-30 | 2017-07-18 | Janssen Biotech, Inc. | Anti-tissue factor antibodies and compositions |
WO2005000871A2 (en) | 2003-06-23 | 2005-01-06 | Centocor, Inc. | Peptides antagonistic to an anti-angiogenic antibody and uses therefor |
WO2005068504A1 (ja) * | 2004-01-19 | 2005-07-28 | Medical And Biological Laboratories Co., Ltd. | 炎症性サイトカイン抑制剤 |
AU2012216372B2 (en) * | 2004-04-02 | 2015-01-22 | The Regents Of The University Of California | Methods and compositions for treating and preventing disease associated with alphaVbeta5 integrin |
AU2005229015C1 (en) * | 2004-04-02 | 2013-01-17 | The Regents Of The University Of California | Methods and compositions for treating and preventing disease associated with alphaVbeta5 integrin |
US20060008415A1 (en) * | 2004-06-25 | 2006-01-12 | Protein Design Labs, Inc. | Stable liquid and lyophilized formulation of proteins |
US20060035239A1 (en) * | 2004-08-06 | 2006-02-16 | Applera Corporation | Method and compositions for treating diseases targeting CD51 |
KR101281501B1 (ko) * | 2004-12-09 | 2013-07-15 | 얀센 바이오테크 인코포레이티드 | 항인테그린 면역 컨쥬게이트, 방법 및 용도 |
CN104072614B (zh) | 2005-07-08 | 2017-04-26 | 生物基因Ma公司 | 抗-αvβ6 抗体及其用途 |
EP2046374A4 (en) | 2006-07-10 | 2010-05-05 | Biogen Idec Inc | COMPOSITIONS AND METHODS FOR GROWTH INHIBITION OF SMAD4-DEFICIENT TUMORS |
US8911964B2 (en) | 2006-09-13 | 2014-12-16 | Abbvie Inc. | Fed-batch method of making human anti-TNF-alpha antibody |
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WO2008141274A1 (en) | 2007-05-11 | 2008-11-20 | Centocor, Inc. | Anti-alpha v immunoliposome composition, methods and uses |
WO2008141276A1 (en) * | 2007-05-11 | 2008-11-20 | Centocor, Inc. | Anti-alpha-v immunoliposome composition, methods and uses |
WO2008141278A1 (en) * | 2007-05-11 | 2008-11-20 | Centocor, Inc. | Method for preparing antibody conjugates |
CA2700860C (en) * | 2007-10-01 | 2016-07-19 | Jonathan A. Terrett | Human antibodies that bind mesothelin, and uses thereof |
BRPI0907046A2 (pt) | 2008-01-18 | 2015-07-28 | Medimmune Llc | Anticorpo de cisteína engenheirada, ácido nucleico isolado, vetor, célula hospedeira, conjugado de anticorpo, composição farmacêutica, métodos de detecção de câncer, doenças ou distúrbios autoimunes, inflamatórios ou infecciosos em um indivíduo e de inibição de proliferação de uma célula alvo |
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EP2456460A4 (en) | 2009-07-24 | 2013-02-20 | Univ California | METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING INEGRINE V ASSOCIATED DISEASES |
EP2848632B1 (en) | 2010-02-23 | 2019-07-10 | Sanofi | Human igg1 fc with improved cdc and adcc activity |
US8993844B1 (en) | 2010-05-27 | 2015-03-31 | University Of Wyoming | Production of spider silk protein in corn |
CN103429616B (zh) * | 2010-09-27 | 2016-08-10 | 詹森生物科技公司 | 结合人胶原ii的抗体 |
US8906649B2 (en) | 2010-09-27 | 2014-12-09 | Janssen Biotech, Inc. | Antibodies binding human collagen II |
WO2012143495A2 (de) | 2011-04-21 | 2012-10-26 | Bayer Intellectual Property Gmbh | Neue binder-wirkstoff konjugate (adcs) und ihre verwendung |
WO2012149197A2 (en) | 2011-04-27 | 2012-11-01 | Abbott Laboratories | Methods for controlling the galactosylation profile of recombinantly-expressed proteins |
KR20140084078A (ko) | 2011-10-31 | 2014-07-04 | 제넨테크, 인크. | 항체 제제 |
US9181572B2 (en) | 2012-04-20 | 2015-11-10 | Abbvie, Inc. | Methods to modulate lysine variant distribution |
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-
2001
- 2001-08-01 US US09/920,267 patent/US7288390B2/en not_active Expired - Fee Related
- 2001-08-07 AU AU8316701A patent/AU8316701A/xx active Pending
- 2001-08-07 PL PL366211A patent/PL213030B1/pl unknown
- 2001-08-07 AT AT01961945T patent/ATE470714T1/de active
- 2001-08-07 BR BR0113112-5A patent/BR0113112A/pt not_active Application Discontinuation
- 2001-08-07 RS YUP-94/03A patent/RS51197B/sr unknown
- 2001-08-07 PT PT01961945T patent/PT1309693E/pt unknown
- 2001-08-07 ES ES01961945T patent/ES2346041T3/es not_active Expired - Lifetime
- 2001-08-07 NZ NZ524146A patent/NZ524146A/en not_active IP Right Cessation
- 2001-08-07 MX MXPA03001230A patent/MXPA03001230A/es active IP Right Grant
- 2001-08-07 EA EA200300244A patent/EA007617B1/ru not_active IP Right Cessation
- 2001-08-07 WO PCT/US2001/024784 patent/WO2002012501A2/en active IP Right Grant
- 2001-08-07 EP EP01961945A patent/EP1309693B1/en not_active Expired - Lifetime
- 2001-08-07 EP EP10165270A patent/EP2253646A1/en not_active Withdrawn
- 2001-08-07 DK DK01961945.1T patent/DK1309693T3/da active
- 2001-08-07 KR KR1020037001834A patent/KR100832486B1/ko not_active IP Right Cessation
- 2001-08-07 HU HU0302128A patent/HU229418B1/hu not_active IP Right Cessation
- 2001-08-07 JP JP2002517789A patent/JP5014557B2/ja not_active Expired - Fee Related
- 2001-08-07 DE DE60142342T patent/DE60142342D1/de not_active Expired - Lifetime
- 2001-08-07 CA CA2418962A patent/CA2418962C/en not_active Expired - Fee Related
- 2001-08-07 CN CN018169384A patent/CN1468307B/zh not_active Expired - Fee Related
- 2001-08-07 IL IL15432601A patent/IL154326A0/xx not_active IP Right Cessation
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2003
- 2003-02-07 HR HRP20030088AA patent/HRP20030088B1/hr not_active IP Right Cessation
- 2003-02-07 NO NO20030621A patent/NO334999B1/no not_active IP Right Cessation
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