IL152845A0 - Fused heterocyclic compounds and pharmaceutical compositions containing the same - Google Patents

Fused heterocyclic compounds and pharmaceutical compositions containing the same

Info

Publication number
IL152845A0
IL152845A0 IL15284501A IL15284501A IL152845A0 IL 152845 A0 IL152845 A0 IL 152845A0 IL 15284501 A IL15284501 A IL 15284501A IL 15284501 A IL15284501 A IL 15284501A IL 152845 A0 IL152845 A0 IL 152845A0
Authority
IL
Israel
Prior art keywords
group
ring
same
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL15284501A
Other languages
English (en)
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of IL152845A0 publication Critical patent/IL152845A0/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
IL15284501A 2000-06-07 2001-06-05 Fused heterocyclic compounds and pharmaceutical compositions containing the same IL152845A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20992900P 2000-06-07 2000-06-07
PCT/US2001/018243 WO2001094351A1 (en) 2000-06-07 2001-06-05 Caspase inhibitors and uses thereof

Publications (1)

Publication Number Publication Date
IL152845A0 true IL152845A0 (en) 2003-06-24

Family

ID=22780912

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15284501A IL152845A0 (en) 2000-06-07 2001-06-05 Fused heterocyclic compounds and pharmaceutical compositions containing the same

Country Status (11)

Country Link
US (3) US7407964B2 (enExample)
EP (1) EP1289993B9 (enExample)
JP (1) JP2003535865A (enExample)
KR (1) KR20030025235A (enExample)
AT (1) ATE377010T1 (enExample)
AU (2) AU2001275279B2 (enExample)
CA (1) CA2409015A1 (enExample)
DE (1) DE60131160T2 (enExample)
ES (1) ES2295171T3 (enExample)
IL (1) IL152845A0 (enExample)
WO (1) WO2001094351A1 (enExample)

Families Citing this family (36)

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Publication number Priority date Publication date Assignee Title
AU4213500A (en) 1999-04-09 2000-11-14 Cytovia, Inc. Caspase inhibitors and the use thereof
DK1163208T3 (da) 1999-08-06 2004-08-16 Vertex Pharma Caspaseinhibitorer og anvendelser deraf
BR0013666A (pt) 1999-08-27 2002-05-14 Cytovia Inc "alfa"-hidróxi-ácidos substituìdos inibidores de caspases e o seu uso
PE20011350A1 (es) 2000-05-19 2002-01-15 Vertex Pharma PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE)
AU2001275279B2 (en) * 2000-06-07 2007-01-04 Vertex Pharmaceuticals Incorporated Caspase inhibitors and uses thereof
WO2003068242A1 (en) 2002-02-11 2003-08-21 Vertex Pharmaceuticals Incorporated Phospholipids as caspase inhibitor prodrugs
US7960398B2 (en) 2002-04-19 2011-06-14 Vertex Pharmaceuticals Incorporated Regulation of TNF-alpha
PL374598A1 (en) 2002-06-28 2005-10-31 Vertex Pharmaceuticals Incorporated Caspase inhibitors and uses thereof
CN100366612C (zh) * 2002-12-20 2008-02-06 沃泰克斯药物股份有限公司 4-氧代-3-(1-氧代-1h-异喹啉-2-基乙酰氨基)-戊酸酯和酰胺衍生物及其作为天冬氨酸特异性半胱氨酸蛋白酶抑制剂的用途
AU2003292436B2 (en) * 2002-12-27 2009-07-30 Msd Italia S.R.L. Tetrahydro-4H-pyrido[1,2-A]pyrimidines and related compounds useful as HIV integrase inhibitors
US20060217299A1 (en) * 2003-02-24 2006-09-28 Hirofumi Doi Degradation inhibitor for hepatitis b virus x interacting protein
PE20050159A1 (es) 2003-05-27 2005-04-19 Vertex Pharma Derivados de acido 3-[2-(3-amino-2-oxo-2h-piridin-1-il)-acetilamino]-4-oxo-pentanoico como inhibidores de caspasa
IL158599A0 (en) * 2003-10-26 2004-05-12 Yeda Res & Dev Methods of modulating hematopoiesis
WO2005117846A2 (en) 2004-05-27 2005-12-15 Vertex Pharmaceuticals Incorporated Ice inhibitors for the treatment of autoinflammatory diseases
EP1718639A2 (en) 2004-02-27 2006-11-08 Vertex Pharmaceuticals Incorporated Caspase inhibitors and uses thereof
CA2768700C (en) * 2004-03-12 2014-04-29 Vertex Pharmaceuticals Incorporated Processes and intermediates for the preparation of aspartic acetal caspase inhibitors
US20060128696A1 (en) * 2004-05-15 2006-06-15 Annamaria Vezzani Treating seizures using ice inhibitors
CA2580643C (en) * 2004-09-17 2018-06-12 Biomas, Ltd. Use of tellurium compounds for inhibition of interleukin-converting enzyme
ATE529430T1 (de) * 2005-07-28 2011-11-15 Vertex Pharma Caspase-hemmer-propharmaka
KR20080083672A (ko) * 2005-12-22 2008-09-18 쉐링 코포레이션 트롬빈 수용체 길항제로서 옥사졸로이소퀴놀린 유도체
WO2009140765A1 (en) 2008-05-21 2009-11-26 New World Laboratories Inc. Selective caspase inhibitors and uses thereof
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