ES2295171T3 - Inhibidores de caspasa y sus usos. - Google Patents
Inhibidores de caspasa y sus usos. Download PDFInfo
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- ES2295171T3 ES2295171T3 ES01941972T ES01941972T ES2295171T3 ES 2295171 T3 ES2295171 T3 ES 2295171T3 ES 01941972 T ES01941972 T ES 01941972T ES 01941972 T ES01941972 T ES 01941972T ES 2295171 T3 ES2295171 T3 ES 2295171T3
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- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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| JPWO2004073742A1 (ja) * | 2003-02-24 | 2006-06-01 | 第一製薬株式会社 | Ｂ型肝炎ウイルスｘ相互作用蛋白質の分解阻害剤 |
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| RU2382780C2 (ru) * | 2004-02-27 | 2010-02-27 | Вертекс Фармасьютикалз Инкорпорейтед | Ингибиторы каспаз и их применение |
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| PL217743B1 (pl) * | 2004-05-15 | 2014-08-29 | Vertex Pharma | Zastosowanie inhibitorów ICE/kaspazy-1 do leczenia napadów i konwulsji w epilepsji oraz zawierające je kompozycja farmaceutyczna i zestaw |
| CN1980658A (zh) | 2004-05-27 | 2007-06-13 | 沃泰克斯药物股份有限公司 | 治疗自身炎性疾病的ice抑制剂 |
| ES2312012T3 (es) * | 2004-09-17 | 2009-02-16 | Biomas Ltd. | Nuevos compuestos de telurio y su uso como inmunomodulares. |
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| EP2288615B1 (en) | 2008-05-21 | 2017-06-21 | Genesis Technologies Limited | Selective caspase inhibitors and uses thereof |
| US8518942B2 (en) | 2008-08-06 | 2013-08-27 | Buck Institute For Research On Aging | Caspase inhibitors and uses thereof |
| EP2221299A3 (en) | 2009-02-11 | 2010-11-03 | Dr. Reddy's Laboratories Ltd. | Preparation of cilazapril intermediates |
| US9045524B2 (en) | 2009-05-21 | 2015-06-02 | Novagenesis Foundation | Selective caspase inhibitors and uses thereof |
| CN101580505B (zh) * | 2009-05-27 | 2014-09-10 | 沈阳药科大学 | 吡咯并[2，1-b]喹唑啉类天然产物的衍生物及其制备方法和用途 |
| US9365612B2 (en) | 2010-01-29 | 2016-06-14 | United States Of America As Represented By The Secretary, Department Of Health And Human Services | Caspase inhibitors |
| JP6006908B2 (ja) | 2010-11-05 | 2016-10-12 | ブランダイス ユニバーシティＢｒａｎｄｅｉｓ Ｕｎｉｖｅｒｓｉｔｙ | Ｉｃｅ阻害化合物およびその使用 |
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| US9956260B1 (en) | 2011-07-22 | 2018-05-01 | The J. David Gladstone Institutes | Treatment of HIV-1 infection and AIDS |
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| CN105636953B (zh) * | 2013-07-31 | 2018-01-02 | 诺华股份有限公司 | 1,4‑二取代的哒嗪衍生物及其用于治疗与smn缺乏相关的病症的用途 |
| MX2016014731A (es) | 2014-05-12 | 2017-05-04 | Conatus Pharmaceuticals Inc | Tratamiento de las complicaciones de la enfermedad cronica del higado con enfermedades de caspasa. |
| WO2017079566A1 (en) | 2015-11-05 | 2017-05-11 | Conatus Pharmaceuticals, Inc. | Caspase inhibitors for use in the treatment of liver cancer |
| KR20180101418A (ko) | 2015-12-31 | 2018-09-12 | 코나터스 파마슈티칼스, 인크. | 간 질환의 치료에서의 카스파제 억제제의 사용 방법 |
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-
2001
- 2001-06-05 DE DE60131160T patent/DE60131160T2/de not_active Expired - Lifetime
- 2001-06-05 EP EP01941972A patent/EP1289993B9/en not_active Expired - Lifetime
- 2001-06-05 AU AU7527901A patent/AU7527901A/xx active Pending
- 2001-06-05 KR KR1020027016636A patent/KR20030025235A/ko not_active Withdrawn
- 2001-06-05 JP JP2002501900A patent/JP2003535865A/ja active Pending
- 2001-06-05 AU AU2001275279A patent/AU2001275279B2/en not_active Ceased
- 2001-06-05 AT AT01941972T patent/ATE377010T1/de not_active IP Right Cessation
- 2001-06-05 IL IL15284501A patent/IL152845A0/xx unknown
- 2001-06-05 ES ES01941972T patent/ES2295171T3/es not_active Expired - Lifetime
- 2001-06-05 CA CA002409015A patent/CA2409015A1/en not_active Abandoned
- 2001-06-05 WO PCT/US2001/018243 patent/WO2001094351A1/en not_active Ceased
- 2001-06-07 US US09/877,832 patent/US7407964B2/en not_active Expired - Fee Related
-
2008
- 2008-07-01 US US12/165,952 patent/US7829561B2/en not_active Expired - Fee Related
-
2010
- 2010-09-16 US US12/883,424 patent/US7968716B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR20030025235A (ko) | 2003-03-28 |
| JP2003535865A (ja) | 2003-12-02 |
| AU2001275279B2 (en) | 2007-01-04 |
| IL152845A0 (en) | 2003-06-24 |
| WO2001094351A1 (en) | 2001-12-13 |
| EP1289993B1 (en) | 2007-10-31 |
| DE60131160D1 (de) | 2007-12-13 |
| US7968716B2 (en) | 2011-06-28 |
| ATE377010T1 (de) | 2007-11-15 |
| US7407964B2 (en) | 2008-08-05 |
| EP1289993A1 (en) | 2003-03-12 |
| CA2409015A1 (en) | 2001-12-13 |
| US7829561B2 (en) | 2010-11-09 |
| US20110003824A1 (en) | 2011-01-06 |
| US20090023739A1 (en) | 2009-01-22 |
| AU7527901A (en) | 2001-12-17 |
| DE60131160T2 (de) | 2008-08-07 |
| EP1289993B9 (en) | 2008-08-20 |
| US20020045623A1 (en) | 2002-04-18 |
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