DE69815509D1 - Heterozyklische verbindungen die als oxido-squalen-zyklase-inhibitoren anwendung finden - Google Patents

Heterozyklische verbindungen die als oxido-squalen-zyklase-inhibitoren anwendung finden

Info

Publication number
DE69815509D1
DE69815509D1 DE69815509T DE69815509T DE69815509D1 DE 69815509 D1 DE69815509 D1 DE 69815509D1 DE 69815509 T DE69815509 T DE 69815509T DE 69815509 T DE69815509 T DE 69815509T DE 69815509 D1 DE69815509 D1 DE 69815509D1
Authority
DE
Germany
Prior art keywords
oxido
squalen
apply
heterocyclic compounds
heterocyclic derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69815509T
Other languages
English (en)
Other versions
DE69815509T2 (de
Inventor
Robert Brown
John Newcombe
John Foubister
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9702945.8A external-priority patent/GB9702945D0/en
Priority claimed from GBGB9715735.8A external-priority patent/GB9715735D0/en
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of DE69815509D1 publication Critical patent/DE69815509D1/de
Application granted granted Critical
Publication of DE69815509T2 publication Critical patent/DE69815509T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
DE69815509T 1997-02-13 1998-02-09 Heterozyklische verbindungen die als oxido-squalen-zyklase-inhibitoren anwendung finden Expired - Fee Related DE69815509T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9702945 1997-02-13
GBGB9702945.8A GB9702945D0 (en) 1997-02-13 1997-02-13 Heterocyclic compounds
GB9715735 1997-07-26
GBGB9715735.8A GB9715735D0 (en) 1997-07-26 1997-07-26 Heterocyclic compounds
PCT/GB1998/000406 WO1998035959A1 (en) 1997-02-13 1998-02-09 Heterocyclic compounds useful as oxido-squalene cyclase inhibitors

Publications (2)

Publication Number Publication Date
DE69815509D1 true DE69815509D1 (de) 2003-07-17
DE69815509T2 DE69815509T2 (de) 2004-05-13

Family

ID=26310985

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69815509T Expired - Fee Related DE69815509T2 (de) 1997-02-13 1998-02-09 Heterozyklische verbindungen die als oxido-squalen-zyklase-inhibitoren anwendung finden

Country Status (10)

Country Link
US (1) US6391880B1 (de)
EP (1) EP0966462B1 (de)
JP (1) JP2001511799A (de)
AT (1) ATE242774T1 (de)
AU (1) AU5999798A (de)
DE (1) DE69815509T2 (de)
DK (1) DK0966462T3 (de)
ES (1) ES2201438T3 (de)
PT (1) PT966462E (de)
WO (1) WO1998035959A1 (de)

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GB9602166D0 (en) * 1996-02-02 1996-04-03 Zeneca Ltd Aminoheterocyclic derivatives
GB9715892D0 (en) 1997-07-29 1997-10-01 Zeneca Ltd Heterocyclic compounds
GB9902989D0 (en) 1999-02-11 1999-03-31 Zeneca Ltd Heterocyclic derivatives
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WO2002036587A2 (en) 2000-11-01 2002-05-10 Cor Therapeutics, Inc. Process for the production of 4-quinazolinylpiperazin-1-carboxylic acid phenylamides
AU2006264651A1 (en) * 2005-06-30 2007-01-11 Prosidion Limited G-protein coupled receptor agonists
BRPI0809680A2 (pt) * 2007-03-30 2014-10-07 Hoffmann La Roche Compostos, processo para a sua manufatura, composições farmacêuticas que os compreendem, método para o tratamento terapêutico e/ou profilático de enfermidades que são moduladas por agonistas de lxr alfa e/ou lxr beta e uso dos compostos.
EP3233799B1 (de) 2014-12-19 2021-05-19 The Broad Institute, Inc. Dopamin-d2-rezeptor-liganden
WO2016100940A1 (en) 2014-12-19 2016-06-23 The Broad Institute, Inc. Dopamine d2 receptor ligands

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GB9715892D0 (en) * 1997-07-29 1997-10-01 Zeneca Ltd Heterocyclic compounds

Also Published As

Publication number Publication date
JP2001511799A (ja) 2001-08-14
EP0966462A1 (de) 1999-12-29
ES2201438T3 (es) 2004-03-16
ATE242774T1 (de) 2003-06-15
PT966462E (pt) 2003-10-31
EP0966462B1 (de) 2003-06-11
AU5999798A (en) 1998-09-08
US6391880B1 (en) 2002-05-21
DK0966462T3 (da) 2003-09-22
WO1998035959A1 (en) 1998-08-20
DE69815509T2 (de) 2004-05-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee