DK0966462T3 - Heterocykliske forbindelser, der er egnede som oxidosqualencyklaseinhibitorer - Google Patents

Heterocykliske forbindelser, der er egnede som oxidosqualencyklaseinhibitorer

Info

Publication number
DK0966462T3
DK0966462T3 DK98903175T DK98903175T DK0966462T3 DK 0966462 T3 DK0966462 T3 DK 0966462T3 DK 98903175 T DK98903175 T DK 98903175T DK 98903175 T DK98903175 T DK 98903175T DK 0966462 T3 DK0966462 T3 DK 0966462T3
Authority
DK
Denmark
Prior art keywords
heterocyclic compounds
compounds useful
heterocyclic derivatives
cyclase inhibitors
oxidosqualene cyclase
Prior art date
Application number
DK98903175T
Other languages
Danish (da)
English (en)
Inventor
George Robert Brown
Nicholas John Newcombe
Alan John Foubister
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9702945.8A external-priority patent/GB9702945D0/en
Priority claimed from GBGB9715735.8A external-priority patent/GB9715735D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK0966462T3 publication Critical patent/DK0966462T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
DK98903175T 1997-02-13 1998-02-09 Heterocykliske forbindelser, der er egnede som oxidosqualencyklaseinhibitorer DK0966462T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9702945.8A GB9702945D0 (en) 1997-02-13 1997-02-13 Heterocyclic compounds
GBGB9715735.8A GB9715735D0 (en) 1997-07-26 1997-07-26 Heterocyclic compounds
PCT/GB1998/000406 WO1998035959A1 (en) 1997-02-13 1998-02-09 Heterocyclic compounds useful as oxido-squalene cyclase inhibitors

Publications (1)

Publication Number Publication Date
DK0966462T3 true DK0966462T3 (da) 2003-09-22

Family

ID=26310985

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98903175T DK0966462T3 (da) 1997-02-13 1998-02-09 Heterocykliske forbindelser, der er egnede som oxidosqualencyklaseinhibitorer

Country Status (10)

Country Link
US (1) US6391880B1 (de)
EP (1) EP0966462B1 (de)
JP (1) JP2001511799A (de)
AT (1) ATE242774T1 (de)
AU (1) AU5999798A (de)
DE (1) DE69815509T2 (de)
DK (1) DK0966462T3 (de)
ES (1) ES2201438T3 (de)
PT (1) PT966462E (de)
WO (1) WO1998035959A1 (de)

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GB9602166D0 (en) * 1996-02-02 1996-04-03 Zeneca Ltd Aminoheterocyclic derivatives
GB9715892D0 (en) 1997-07-29 1997-10-01 Zeneca Ltd Heterocyclic compounds
GB9902989D0 (en) 1999-02-11 1999-03-31 Zeneca Ltd Heterocyclic derivatives
EP1194151A4 (de) * 1999-06-23 2003-01-15 Merck & Co Inc Antagonisten der integrin rezeptoren
AU2002217999A1 (en) 2000-11-01 2002-05-15 Cor Therapeutics, Inc. Process for the production of 4-quinazolinylpiperazin-1-carboxylic acid phenylamides
JP2008545010A (ja) * 2005-06-30 2008-12-11 プロシディオン・リミテッド Ｇタンパク質共役受容体アゴニスト
EP2142533B1 (de) * 2007-03-30 2011-11-16 F. Hoffmann-La Roche AG Imidazolidinonderivate
US10633336B2 (en) 2014-12-19 2020-04-28 The Broad Institute, Inc. Dopamine D2 receptor ligands
EP3233799B1 (de) 2014-12-19 2021-05-19 The Broad Institute, Inc. Dopamin-d2-rezeptor-liganden

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GB9602294D0 (en) 1996-02-05 1996-04-03 Zeneca Ltd Heterocyclic compounds
ES2186874T3 (es) 1996-02-22 2003-05-16 Bristol Myers Squibb Pharma Co Analogos de m-amidinofenilo como inhibidores del factor xa.
PL331599A1 (en) 1996-08-14 1999-08-02 Zeneca Ltd Substituted derivatives of pyrimidine and their pharmaceutical application
UA56197C2 (uk) 1996-11-08 2003-05-15 Зенека Лімітед Гетероциклічні похідні
GB9715892D0 (en) * 1997-07-29 1997-10-01 Zeneca Ltd Heterocyclic compounds

Also Published As

Publication number Publication date
DE69815509D1 (de) 2003-07-17
PT966462E (pt) 2003-10-31
ATE242774T1 (de) 2003-06-15
JP2001511799A (ja) 2001-08-14
AU5999798A (en) 1998-09-08
ES2201438T3 (es) 2004-03-16
WO1998035959A1 (en) 1998-08-20
EP0966462A1 (de) 1999-12-29
DE69815509T2 (de) 2004-05-13
US6391880B1 (en) 2002-05-21
EP0966462B1 (de) 2003-06-11

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