IL152073A0 - Percyquinnin, a process for its production and its use as a pharmaceutical - Google Patents

Percyquinnin, a process for its production and its use as a pharmaceutical

Info

Publication number
IL152073A0
IL152073A0 IL15207301A IL15207301A IL152073A0 IL 152073 A0 IL152073 A0 IL 152073A0 IL 15207301 A IL15207301 A IL 15207301A IL 15207301 A IL15207301 A IL 15207301A IL 152073 A0 IL152073 A0 IL 152073A0
Authority
IL
Israel
Prior art keywords
percyquinnin
production
pharmaceutically acceptable
pharmaceutical
dsm
Prior art date
Application number
IL15207301A
Other languages
English (en)
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of IL152073A0 publication Critical patent/IL152073A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Epoxy Compounds (AREA)
IL15207301A 2000-04-07 2001-03-24 Percyquinnin, a process for its production and its use as a pharmaceutical IL152073A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00107536A EP1142886A1 (fr) 2000-04-07 2000-04-07 Percyquinine, procédé pour sa production et son utilisation comme produit pharmaceutique
PCT/EP2001/003392 WO2001077094A1 (fr) 2000-04-07 2001-03-24 Percyquinnine, procede pour sa production, et son utilisation comme medicament

Publications (1)

Publication Number Publication Date
IL152073A0 true IL152073A0 (en) 2003-05-29

Family

ID=8168397

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15207301A IL152073A0 (en) 2000-04-07 2001-03-24 Percyquinnin, a process for its production and its use as a pharmaceutical
IL152073A IL152073A (en) 2000-04-07 2002-10-02 Persiquin, a process for its preparation, and its use as a pharmaceutical

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL152073A IL152073A (en) 2000-04-07 2002-10-02 Persiquin, a process for its preparation, and its use as a pharmaceutical

Country Status (30)

Country Link
US (1) US6596518B2 (fr)
EP (2) EP1142886A1 (fr)
JP (1) JP2003530391A (fr)
KR (1) KR100791798B1 (fr)
CN (1) CN1199959C (fr)
AT (1) ATE269855T1 (fr)
AU (2) AU784902B2 (fr)
BR (1) BR0109854A (fr)
CA (1) CA2405066A1 (fr)
CZ (1) CZ20023310A3 (fr)
DE (1) DE60103995T2 (fr)
DK (1) DK1274698T3 (fr)
EE (1) EE200200572A (fr)
ES (1) ES2222992T3 (fr)
HK (1) HK1052005A1 (fr)
HR (1) HRP20020796A2 (fr)
HU (1) HUP0300327A3 (fr)
IL (2) IL152073A0 (fr)
MX (1) MXPA02007895A (fr)
NO (1) NO20024772L (fr)
NZ (1) NZ521782A (fr)
PL (1) PL357909A1 (fr)
PT (1) PT1274698E (fr)
RS (1) RS50140B (fr)
RU (1) RU2266290C2 (fr)
SI (1) SI1274698T1 (fr)
SK (1) SK14322002A3 (fr)
TR (1) TR200401739T4 (fr)
WO (1) WO2001077094A1 (fr)
ZA (1) ZA200207910B (fr)

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EP1142886A1 (fr) * 2000-04-07 2001-10-10 Aventis Pharma Deutschland GmbH Percyquinine, procédé pour sa production et son utilisation comme produit pharmaceutique
US7105526B2 (en) 2002-06-28 2006-09-12 Banyu Pharmaceuticals Co., Ltd. Benzimidazole derivatives
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
JP4765627B2 (ja) 2003-09-22 2011-09-07 Ｍｓｄ株式会社 新規ピペリジン誘導体
US20080125403A1 (en) 2004-04-02 2008-05-29 Merck & Co., Inc. Method of Treating Men with Metabolic and Anthropometric Disorders
AU2005272627A1 (en) 2004-08-13 2006-02-23 Amgen Inc. Substituted benzofused heterocycles
CA2618112A1 (fr) 2005-08-10 2007-02-15 Banyu Pharmaceutical Co., Ltd. Compose de pyridone
EP1921065B1 (fr) 2005-08-24 2010-10-20 Banyu Pharmaceutical Co., Ltd. Dérivé phénylpyridone
US20090264426A1 (en) 2005-09-07 2009-10-22 Shunji Sakuraba Bicyclic aromatic substituted pyridone derivative
CN101277960A (zh) 2005-09-29 2008-10-01 默克公司 作为黑皮质素-4受体调节剂的酰化螺哌啶衍生物
WO2007048027A2 (fr) 2005-10-21 2007-04-26 Novartis Ag Combinaison de composes organiques
AU2006307046A1 (en) 2005-10-27 2007-05-03 Msd K.K. Novel benzoxathiin derivative
JP4371164B2 (ja) 2005-11-10 2009-11-25 萬有製薬株式会社 アザ置換スピロ誘導体
CN100417650C (zh) * 2006-08-17 2008-09-10 中国科学院昆明植物研究所 韧革菌素及其制备方法和在药物上的应用
CA2664113C (fr) 2006-09-22 2013-05-28 Merck & Co., Inc. Utilisation de la platencine et de la platensimycine en tant qu'inhibiteurs de la synthese des acides gras pour traiter l'obesite, lediabete et le cancer
EP2072519A4 (fr) 2006-09-28 2009-10-21 Banyu Pharma Co Ltd Dérivé de diarylcétimine
US8106086B2 (en) 2007-04-02 2012-01-31 Msd K.K. Indoledione derivative
WO2008151257A2 (fr) 2007-06-04 2008-12-11 Synergy Pharmaceuticals Inc. Agonistes de guanylase cyclase utiles pour le traitement de troubles gastro-intestinaux, d'inflammation, de cancer et d'autres troubles
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US20110015181A1 (en) 2008-03-06 2011-01-20 Makoto Ando Alkylaminopyridine derivative
CN101981025A (zh) 2008-03-28 2011-02-23 万有制药株式会社 具有黑色素浓缩激素受体拮抗作用的二芳基甲基酰胺衍生物
AU2009256157B2 (en) 2008-06-04 2014-12-18 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
AU2009261248A1 (en) 2008-06-19 2009-12-23 Banyu Pharmaceutical Co., Ltd. Spirodiamine-diarylketoxime derivative
EP2321341B1 (fr) 2008-07-16 2017-02-22 Synergy Pharmaceuticals Inc. Agonistes de guanylate cyclase utiles pour le traitement de troubles gastro-intestinaux, inflammatoires, cancéreux et autres
WO2010013595A1 (fr) 2008-07-30 2010-02-04 萬有製薬株式会社 Dérivé de cycloalkylamine à noyaux fusionnés à (5 chaînons)-(5 chaînons) ou (5 chaînons)–(6 chaînons)
MX2011004258A (es) 2008-10-22 2011-06-01 Merck Sharp & Dohme Derivados de bencimidazol ciclicos novedosos utiles como agentes anti-diabeticos.
PE20110852A1 (es) 2008-10-30 2011-11-25 Merck Sharp & Dohme Antagonistas del receptor de orexina de isonicotinamida
EP2362731B1 (fr) 2008-10-31 2016-04-06 Merck Sharp & Dohme Corp. Nouveaux agents antidiabétiques utiles avec des dérivés de benzimidazole cycliques
CA2786314A1 (fr) 2010-02-25 2011-09-01 Merck Sharp & Dohme Corp. Nouveaux derives benzimidazole cycliques utiles comme agents antidiabetiques
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
BR122021002201A8 (pt) 2011-02-25 2023-04-11 Merck Sharp & Dohme Composto, composição, uso de um composto, e, método de tratamento de um distúrbio, condição ou doença
AR088352A1 (es) 2011-10-19 2014-05-28 Merck Sharp & Dohme Antagonistas del receptor de 2-piridiloxi-4-nitrilo orexina
KR20150036245A (ko) 2012-08-02 2015-04-07 머크 샤프 앤드 돔 코포레이션 항당뇨병 트리시클릭 화합물
MX2015010935A (es) 2013-02-22 2015-10-29 Merck Sharp & Dohme Compuestos biciclicos antidiabeticos.
US9650375B2 (en) 2013-03-14 2017-05-16 Merck Sharp & Dohme Corp. Indole derivatives useful as anti-diabetic agents
WO2014151206A1 (fr) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonistes de la guanylate cyclase et leurs utilisations
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
WO2014197720A2 (fr) 2013-06-05 2014-12-11 Synergy Pharmaceuticals, Inc. Agonistes ultra-purs de guanylate cyclase c, leur procédé de production et d'utilisation
WO2015051496A1 (fr) 2013-10-08 2015-04-16 Merck Sharp & Dohme Corp. Composés tricycliques antidiabétiques
MX2017002610A (es) 2014-08-29 2017-10-11 Tes Pharma S R L INHIBIDORES DE ACIDO A-AMINO-ß-CARBOXIMUCONICO SEMIALDEHIDO DESCARBOXILASA.
CN105906500B (zh) * 2016-04-22 2018-06-26 中国科学院昆明植物研究所 具有脂肪酶抑制作用的绵马次酸类化合物及其应用
RU2019114228A (ru) 2016-10-14 2020-11-16 Тес Фарма С.Р.Л. ИНГИБИТОРЫ ДЕКАРБОКСИЛАЗЫ ПОЛУАЛЬДЕГИДА α-АМИНО-β-КАРБОКСИМУКОНОВОЙ КИСЛОТЫ
EP3551176A4 (fr) 2016-12-06 2020-06-24 Merck Sharp & Dohme Corp. Composés hétérocycliques antidiabétiques
US10968232B2 (en) 2016-12-20 2021-04-06 Merck Sharp & Dohme Corp. Antidiabetic spirochroman compounds
CN109055231B (zh) * 2018-07-26 2021-04-27 云南大学 一种真菌发酵液及其应用
AU2019385644A1 (en) 2018-11-20 2021-06-03 Tes Pharma S.R.L. Inhibitors of α-Amino-β-carboxymuconic acid semialdehyde decarboxylase
TW202045476A (zh) 2019-02-13 2020-12-16 美商默沙東藥廠 5-烷基吡咯啶食慾素受體促效劑
WO2021026047A1 (fr) 2019-08-08 2021-02-11 Merck Sharp & Dohme Corp. Agonistes du récepteur de l'orexine de type pyrrolidine et pipéridine hétéroaryle
KR20230053639A (ko) 2020-08-18 2023-04-21 머크 샤프 앤드 돔 엘엘씨 비시클로헵탄 피롤리딘 오렉신 수용체 효능제

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FR2344285A1 (fr) * 1976-03-19 1977-10-14 Roussel Uclaf Nouvelles lactones derivees du cyclopentanol, leur procede de preparation et leur application comme medicaments
US5322779A (en) * 1992-04-16 1994-06-21 The Research And Development Institute, Inc. At Montana State University Taxol production by taxomyces andreanae
EP1142886A1 (fr) * 2000-04-07 2001-10-10 Aventis Pharma Deutschland GmbH Percyquinine, procédé pour sa production et son utilisation comme produit pharmaceutique

Also Published As

Publication number Publication date
CN1418203A (zh) 2003-05-14
NO20024772D0 (no) 2002-10-03
RU2266290C2 (ru) 2005-12-20
ATE269855T1 (de) 2004-07-15
EP1274698A1 (fr) 2003-01-15
AU5621901A (en) 2001-10-23
BR0109854A (pt) 2003-06-03
CN1199959C (zh) 2005-05-04
DE60103995D1 (de) 2004-07-29
PT1274698E (pt) 2004-10-29
NZ521782A (en) 2004-05-28
WO2001077094A1 (fr) 2001-10-18
IL152073A (en) 2007-12-03
AU2006203704B8 (en) 2008-07-10
US20020039768A1 (en) 2002-04-04
KR100791798B1 (ko) 2008-01-04
SI1274698T1 (en) 2004-12-31
AU2006203704A1 (en) 2006-09-21
DE60103995T2 (de) 2005-01-05
RU2002129890A (ru) 2004-03-27
AU2006203704B2 (en) 2008-06-26
CA2405066A1 (fr) 2001-10-18
KR20020084299A (ko) 2002-11-04
HRP20020796A2 (en) 2004-12-31
MXPA02007895A (es) 2002-11-29
HK1052005A1 (en) 2003-08-29
NO20024772L (no) 2002-10-03
PL357909A1 (en) 2004-08-09
YU74002A (sh) 2005-11-28
JP2003530391A (ja) 2003-10-14
RS50140B (sr) 2009-03-25
ES2222992T3 (es) 2005-02-16
US6596518B2 (en) 2003-07-22
HUP0300327A3 (en) 2004-10-28
ZA200207910B (en) 2003-07-21
EP1142886A1 (fr) 2001-10-10
DK1274698T3 (da) 2004-11-01
SK14322002A3 (sk) 2003-05-02
EP1274698B1 (fr) 2004-06-23
CZ20023310A3 (cs) 2003-01-15
TR200401739T4 (tr) 2004-08-23
AU784902B2 (en) 2006-07-20
HUP0300327A2 (hu) 2003-06-28
EE200200572A (et) 2004-04-15

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