HUP0300327A3 - Percyquinnin, a process for its production and its use as a pharmaceutical - Google Patents

Percyquinnin, a process for its production and its use as a pharmaceutical

Info

Publication number
HUP0300327A3
HUP0300327A3 HU0300327A HUP0300327A HUP0300327A3 HU P0300327 A3 HUP0300327 A3 HU P0300327A3 HU 0300327 A HU0300327 A HU 0300327A HU P0300327 A HUP0300327 A HU P0300327A HU P0300327 A3 HUP0300327 A3 HU P0300327A3
Authority
HU
Hungary
Prior art keywords
percyquinnin
pharmaceutical
production
Prior art date
Application number
HU0300327A
Other languages
English (en)
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of HUP0300327A2 publication Critical patent/HUP0300327A2/hu
Publication of HUP0300327A3 publication Critical patent/HUP0300327A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Obesity (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Epoxy Compounds (AREA)
HU0300327A 2000-04-07 2001-03-24 Percyquinnin, a process for its production and its use as a pharmaceutical HUP0300327A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00107536A EP1142886A1 (en) 2000-04-07 2000-04-07 Percyquinnin, a process for its production and its use as a pharmaceutical
PCT/EP2001/003392 WO2001077094A1 (en) 2000-04-07 2001-03-24 Percyquinnin, a process for its production and its use as a pharmaceutical

Publications (2)

Publication Number Publication Date
HUP0300327A2 HUP0300327A2 (hu) 2003-06-28
HUP0300327A3 true HUP0300327A3 (en) 2004-10-28

Family

ID=8168397

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0300327A HUP0300327A3 (en) 2000-04-07 2001-03-24 Percyquinnin, a process for its production and its use as a pharmaceutical

Country Status (30)

Country Link
US (1) US6596518B2 (hu)
EP (2) EP1142886A1 (hu)
JP (1) JP2003530391A (hu)
KR (1) KR100791798B1 (hu)
CN (1) CN1199959C (hu)
AT (1) ATE269855T1 (hu)
AU (2) AU784902B2 (hu)
BR (1) BR0109854A (hu)
CA (1) CA2405066A1 (hu)
CZ (1) CZ20023310A3 (hu)
DE (1) DE60103995T2 (hu)
DK (1) DK1274698T3 (hu)
EE (1) EE200200572A (hu)
ES (1) ES2222992T3 (hu)
HK (1) HK1052005A1 (hu)
HR (1) HRP20020796A2 (hu)
HU (1) HUP0300327A3 (hu)
IL (2) IL152073A0 (hu)
MX (1) MXPA02007895A (hu)
NO (1) NO20024772D0 (hu)
NZ (1) NZ521782A (hu)
PL (1) PL357909A1 (hu)
PT (1) PT1274698E (hu)
RS (1) RS50140B (hu)
RU (1) RU2266290C2 (hu)
SI (1) SI1274698T1 (hu)
SK (1) SK14322002A3 (hu)
TR (1) TR200401739T4 (hu)
WO (1) WO2001077094A1 (hu)
ZA (1) ZA200207910B (hu)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1142886A1 (en) * 2000-04-07 2001-10-10 Aventis Pharma Deutschland GmbH Percyquinnin, a process for its production and its use as a pharmaceutical
US7105526B2 (en) 2002-06-28 2006-09-12 Banyu Pharmaceuticals Co., Ltd. Benzimidazole derivatives
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
US7547693B2 (en) 2003-09-22 2009-06-16 Banyu Pharmaceutical Co. Ltd. Piperidine derivative
US20080125403A1 (en) 2004-04-02 2008-05-29 Merck & Co., Inc. Method of Treating Men with Metabolic and Anthropometric Disorders
EP1784390A2 (en) 2004-08-13 2007-05-16 Amgen Inc. Substituted benzofused heterocycles
WO2007018248A1 (ja) 2005-08-10 2007-02-15 Banyu Pharmaceutical Co., Ltd. ピリドン化合物
WO2007024004A1 (ja) 2005-08-24 2007-03-01 Banyu Pharmaceutical Co., Ltd. フェニルピリドン誘導体
JPWO2007029847A1 (ja) 2005-09-07 2009-03-19 萬有製薬株式会社 二環性芳香族置換ピリドン誘導体
KR20080048502A (ko) 2005-09-29 2008-06-02 머크 앤드 캄파니 인코포레이티드 멜라노코르틴-4 수용체 조절제로서의 아실화스피로피페리딘 유도체
WO2007048027A2 (en) 2005-10-21 2007-04-26 Novartis Ag Combination of a renin-inhibitor and an anti-dyslipidemic agent and/or an antiobesity agent
US8163770B2 (en) 2005-10-27 2012-04-24 Msd. K. K. Benzoxathiin derivative
WO2007055418A1 (ja) 2005-11-10 2007-05-18 Banyu Pharmaceutical Co., Ltd. アザ置換スピロ誘導体
CN100417650C (zh) * 2006-08-17 2008-09-10 中国科学院昆明植物研究所 韧革菌素及其制备方法和在药物上的应用
WO2008039327A2 (en) 2006-09-22 2008-04-03 Merck & Co., Inc. Method of treatment using fatty acid synthesis inhibitors
AU2007301126A1 (en) 2006-09-28 2008-04-03 Banyu Pharmaceutical Co., Ltd. Diaryl ketimine derivative
JP5319518B2 (ja) 2007-04-02 2013-10-16 Ｍｓｄ株式会社 インドールジオン誘導体
ES2393885T7 (es) 2007-06-04 2014-01-30 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
JPWO2009110510A1 (ja) 2008-03-06 2011-07-14 Ｍｓｄ株式会社 アルキルアミノピリジン誘導体
CN101981025A (zh) 2008-03-28 2011-02-23 万有制药株式会社 具有黑色素浓缩激素受体拮抗作用的二芳基甲基酰胺衍生物
ES2522968T3 (es) 2008-06-04 2014-11-19 Synergy Pharmaceuticals Inc. Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
AU2009261248A1 (en) 2008-06-19 2009-12-23 Banyu Pharmaceutical Co., Ltd. Spirodiamine-diarylketoxime derivative
AU2009270833B2 (en) 2008-07-16 2015-02-19 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
WO2010013595A1 (ja) 2008-07-30 2010-02-04 萬有製薬株式会社 ５員－５員又は５員－６員縮環シクロアルキルアミン誘導体
MX2011004258A (es) 2008-10-22 2011-06-01 Merck Sharp & Dohme Derivados de bencimidazol ciclicos novedosos utiles como agentes anti-diabeticos.
BRPI0919876A8 (pt) 2008-10-30 2016-02-10 Merck Sharp & Dohme Composto, composição farmacêutica, uso de um composto, e, método para intensificar a qualidade do sono, para tratar insônia, e para tratar ou controlar obesidade em um paciente mamífero que necessita do mesmo.
CA2741672A1 (en) 2008-10-31 2010-05-06 Merck Sharp & Dohme Corp. Novel cyclic benzimidazole derivatives useful anti-diabetic agents
CA2786314A1 (en) 2010-02-25 2011-09-01 Merck Sharp & Dohme Corp. Novel cyclic benzimidazole derivatives useful anti-diabetic agents
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
KR101668514B1 (ko) 2011-02-25 2016-10-21 머크 샤프 앤드 돔 코포레이션 항당뇨병제로서 유용한 신규 시클릭 아자벤즈이미다졸 유도체
AR088352A1 (es) 2011-10-19 2014-05-28 Merck Sharp & Dohme Antagonistas del receptor de 2-piridiloxi-4-nitrilo orexina
JP2015525782A (ja) 2012-08-02 2015-09-07 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． 抗糖尿病性三環式化合物
RU2015140066A (ru) 2013-02-22 2017-03-30 Мерк Шарп И Доум Корп. Противодиабетические бициклические соединения
US9650375B2 (en) 2013-03-14 2017-05-16 Merck Sharp & Dohme Corp. Indole derivatives useful as anti-diabetic agents
JP2016514671A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼのアゴニストおよびその使用
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
US10011637B2 (en) 2013-06-05 2018-07-03 Synergy Pharmaceuticals, Inc. Ultra-pure agonists of guanylate cyclase C, method of making and using same
WO2015051496A1 (en) 2013-10-08 2015-04-16 Merck Sharp & Dohme Corp. Antidiabetic tricyclic compounds
MX2017002610A (es) 2014-08-29 2017-10-11 Tes Pharma S R L INHIBIDORES DE ACIDO A-AMINO-ß-CARBOXIMUCONICO SEMIALDEHIDO DESCARBOXILASA.
CN105906500B (zh) * 2016-04-22 2018-06-26 中国科学院昆明植物研究所 具有脂肪酶抑制作用的绵马次酸类化合物及其应用
US20180134667A1 (en) 2016-10-14 2018-05-17 TES Pharma S.r.I. Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
WO2018106518A1 (en) 2016-12-06 2018-06-14 Merck Sharp & Dohme Corp. Antidiabetic heterocyclic compounds
US10968232B2 (en) 2016-12-20 2021-04-06 Merck Sharp & Dohme Corp. Antidiabetic spirochroman compounds
CN109055231B (zh) * 2018-07-26 2021-04-27 云南大学 一种真菌发酵液及其应用
MX2021005904A (es) 2018-11-20 2021-09-08 Tes Pharma S R L Inhibidores de la ácido alfa-amino-beta-carboximucónico semialdehído descarboxilasa.
WO2020167706A1 (en) 2019-02-13 2020-08-20 Merck Sharp & Dohme Corp. 5-alkyl pyrrolidine orexin receptor agonists
WO2021026047A1 (en) 2019-08-08 2021-02-11 Merck Sharp & Dohme Corp. Heteroaryl pyrrolidine and piperidine orexin receptor agonists
US20230365533A1 (en) 2020-08-18 2023-11-16 Merck Sharp & Dohme Llc Bicycloheptane pyrrolidine orexin receptor agonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2344285A1 (fr) * 1976-03-19 1977-10-14 Roussel Uclaf Nouvelles lactones derivees du cyclopentanol, leur procede de preparation et leur application comme medicaments
US5322779A (en) * 1992-04-16 1994-06-21 The Research And Development Institute, Inc. At Montana State University Taxol production by taxomyces andreanae
EP1142886A1 (en) * 2000-04-07 2001-10-10 Aventis Pharma Deutschland GmbH Percyquinnin, a process for its production and its use as a pharmaceutical

Also Published As

Publication number Publication date
AU2006203704B2 (en) 2008-06-26
RU2002129890A (ru) 2004-03-27
KR20020084299A (ko) 2002-11-04
RS50140B (sr) 2009-03-25
EP1274698A1 (en) 2003-01-15
HRP20020796A2 (en) 2004-12-31
CN1199959C (zh) 2005-05-04
SI1274698T1 (en) 2004-12-31
HK1052005A1 (en) 2003-08-29
SK14322002A3 (sk) 2003-05-02
DK1274698T3 (da) 2004-11-01
NO20024772L (no) 2002-10-03
CN1418203A (zh) 2003-05-14
BR0109854A (pt) 2003-06-03
RU2266290C2 (ru) 2005-12-20
EP1142886A1 (en) 2001-10-10
AU784902B2 (en) 2006-07-20
NZ521782A (en) 2004-05-28
ATE269855T1 (de) 2004-07-15
AU2006203704B8 (en) 2008-07-10
DE60103995T2 (de) 2005-01-05
JP2003530391A (ja) 2003-10-14
DE60103995D1 (de) 2004-07-29
YU74002A (sh) 2005-11-28
EE200200572A (et) 2004-04-15
IL152073A0 (en) 2003-05-29
AU2006203704A1 (en) 2006-09-21
NO20024772D0 (no) 2002-10-03
ZA200207910B (en) 2003-07-21
KR100791798B1 (ko) 2008-01-04
TR200401739T4 (tr) 2004-08-23
PT1274698E (pt) 2004-10-29
IL152073A (en) 2007-12-03
ES2222992T3 (es) 2005-02-16
HUP0300327A2 (hu) 2003-06-28
MXPA02007895A (es) 2002-11-29
EP1274698B1 (en) 2004-06-23
PL357909A1 (en) 2004-08-09
WO2001077094A1 (en) 2001-10-18
US6596518B2 (en) 2003-07-22
AU5621901A (en) 2001-10-23
CA2405066A1 (en) 2001-10-18
US20020039768A1 (en) 2002-04-04
CZ20023310A3 (cs) 2003-01-15

Similar Documents

Publication Publication Date Title
HUP0300327A3 (en) Percyquinnin, a process for its production and its use as a pharmaceutical
IL153273A0 (en) Acylphenyl urea derivatives, methods for the production thereof and use thereof as a medicament
HK1046681A1 (en) 6-alkenyl-, 6-alkinyl- and 6-epoxy-epothilone derivatives, process for their production, and their use
AU2001262318A1 (en) Acylphenyl urea derivatives, methods for the production thereof and use thereof as a medicament
HUS1400005I1 (hu) Kinazolinszármazékok, elõállításuk, alkalmazásuk és ezeket tartalmazó gyógyszerek
TWI319764B (en) Mercaptoacetylamide derivatives, a process for their preparation and their use
HK1123806A1 (en) Xanthine derivative, production and use thereof as a medicament
AU9181501A (en) Percarboxylated polysaccharides, and a process for their preparation
IL152140A0 (en) Novel, slow-acting betamimetics, a method for their production and their use as medicaments
AU3162001A (en) Medicament, a method for its production and the use thereof
PL374528A1 (en) New effector conjugates, process for their production and their pharmaceutical use
HUP0300222A3 (en) Novel lhrh-antagonists, production and use thereof as medicament
HK1041026A1 (en) Vancoresmycin, a process for its production and its use as a pharmaceutical
HUP0204584A3 (en) Memnopeptides, a process for their preparation and their use
AU6222901A (en) Cyclipostins, a method for their production and the use of the same
HUP0102370A3 (en) Mumbaistatin, a process for its production and its use as a pharmaceutical
AU2001268641A1 (en) Cleaning tablets, and a process for the manufacture of the cleaning tablets
AU2356602A (en) Citrullimycines, a process for their production and their use as pharmaceuticals
HUP0203593A3 (en) Amycomycin, a process for its production and its use as a pharmaceutical
EP1323707A4 (en) 4,8-DODECADIENDINITRILE AND METHOD FOR THE PRODUCTION THEREOF
ZA200501648B (en) New effector conjugates, process for their production and their pharmaceutical use
SI1294682T1 (en) Acylphenyl urea derivatives, methods for the production thereof and use thereof as a medicament
HU0001178D0 (en) New propene-carbon acid-amidoxim derivatives, process for their production and medicaments containing the same
ZA200308591B (en) Crystalline anticholinergic, method for its production, and use thereof in the production of a drug.

Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees