IL147456A0 - Production of proteins - Google Patents

Production of proteins

Info

Publication number
IL147456A0
IL147456A0 IL14745600A IL14745600A IL147456A0 IL 147456 A0 IL147456 A0 IL 147456A0 IL 14745600 A IL14745600 A IL 14745600A IL 14745600 A IL14745600 A IL 14745600A IL 147456 A0 IL147456 A0 IL 147456A0
Authority
IL
Israel
Prior art keywords
sup
heterologous polypeptide
pro
host cell
fusion protein
Prior art date
Application number
IL14745600A
Other languages
English (en)
Original Assignee
Biochemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochemie Gmbh filed Critical Biochemie Gmbh
Publication of IL147456A0 publication Critical patent/IL147456A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/503—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
    • C12N9/506—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses derived from RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
IL14745600A 1999-08-09 2000-08-07 Production of proteins IL147456A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT136799 1999-08-09
PCT/EP2000/007643 WO2001011057A1 (fr) 1999-08-09 2000-08-07 Production de proteines

Publications (1)

Publication Number Publication Date
IL147456A0 true IL147456A0 (en) 2002-08-14

Family

ID=3512357

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14745600A IL147456A0 (en) 1999-08-09 2000-08-07 Production of proteins

Country Status (21)

Country Link
US (2) US6936455B1 (fr)
EP (1) EP1200604B1 (fr)
JP (1) JP4820512B2 (fr)
KR (1) KR20020026366A (fr)
CN (1) CN1230543C (fr)
AT (1) ATE335826T1 (fr)
AU (1) AU775662B2 (fr)
CA (1) CA2379571C (fr)
CZ (1) CZ302366B6 (fr)
DE (1) DE60029968T2 (fr)
ES (1) ES2269173T3 (fr)
HK (1) HK1047128B (fr)
HU (1) HU230231B1 (fr)
IL (1) IL147456A0 (fr)
MX (1) MXPA02001424A (fr)
NO (1) NO328339B1 (fr)
NZ (1) NZ516869A (fr)
PL (1) PL200225B1 (fr)
SK (1) SK287488B6 (fr)
TR (1) TR200200253T2 (fr)
WO (1) WO2001011057A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL203708B1 (pl) * 1999-08-09 2009-11-30 Sandoz Ag Cząsteczka kwasu nukleinowego kodująca białko fuzyjne, wektor ekspresyjny zawierający tę cząsteczkę oraz komórka gospodarza bakteryjnego zawierająca ten wektor
GB2456256B (en) 2004-03-30 2009-08-26 Relypsa Inc Ion binding compositions
GB0508434D0 (en) * 2005-04-26 2005-06-01 Sandoz Ag Organic compounds
CA2605145A1 (fr) * 2005-04-26 2006-11-02 Sandoz Ag Ligands d'affinites
GB0508435D0 (en) * 2005-04-26 2005-06-01 Sandoz Ag Organic compounds
AU2011253661B2 (en) * 2005-04-26 2013-06-13 Boehringer Ingelheim Rcv Gmbh & Co Kg Production of recombinant proteins by autoproteolytic cleavage of a fusion protein
CN107569518A (zh) 2010-08-31 2018-01-12 天野酶制品株式会社 使用了酶的蛋壳膜的溶解方法
EP2684951A1 (fr) 2012-07-13 2014-01-15 Sandoz Ag Procédé de production d'une protéine recombinante d'intérêt
EP2746391A1 (fr) 2012-12-19 2014-06-25 Sandoz Ag Procédé de production d'une protéine recombinante d'intérêt
EP2746390A1 (fr) * 2012-12-19 2014-06-25 Sandoz Ag Procédé de production d'une protéine recombinante d'intérêt
UY35874A (es) 2013-12-12 2015-07-31 Novartis Ag Un proceso para la preparación de una composición de proteínas pegiladas
RU2619217C1 (ru) * 2015-12-04 2017-05-12 Федеральное государственное бюджетное учреждение "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГБУ "ГосНИИгенетика") Температурочувствительный мутантный интеин для нерастворимой экспрессии предшественника целевого белка
CN114539425B (zh) * 2022-02-25 2023-04-28 湖南中晟全肽生化有限公司 一种提高线性多肽生物表达的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4743679A (en) 1986-02-24 1988-05-10 Creative Biomolecules, Inc. Process for producing human epidermal growth factor and analogs thereof
ES2059482T3 (es) 1987-12-23 1994-11-16 Boehringer Ingelheim Int Expresion de la proteasa p2a de hrv2 codificada por virus.
AU742794B2 (en) * 1997-04-25 2002-01-10 Sembiosys Genetics Inc. Method for cleavage of fusion proteins
DK1012307T3 (da) * 1997-08-22 2005-09-05 Roche Diagnostics Gmbh Autokatalytisk aktiverbare zymogene proteaseforstadier og deres anvendelse
AU9341398A (en) * 1997-08-22 1999-03-16 Boehringer Mannheim Gmbh Protease precursors that can be autocatalytically activated and their use

Also Published As

Publication number Publication date
CA2379571A1 (fr) 2001-02-15
TR200200253T2 (tr) 2002-05-21
AU775662B2 (en) 2004-08-12
HU230231B1 (hu) 2015-10-28
MXPA02001424A (es) 2002-08-12
HUP0202519A3 (en) 2004-07-28
HUP0202519A2 (en) 2002-10-28
DE60029968D1 (de) 2006-09-21
EP1200604B1 (fr) 2006-08-09
US20050186564A1 (en) 2005-08-25
HK1047128B (zh) 2007-06-08
NZ516869A (en) 2004-01-30
NO20020633L (no) 2002-04-05
DE60029968T2 (de) 2006-12-21
EP1200604A1 (fr) 2002-05-02
JP4820512B2 (ja) 2011-11-24
PL200225B1 (pl) 2008-12-31
CN1369014A (zh) 2002-09-11
WO2001011057A1 (fr) 2001-02-15
CZ2002481A3 (cs) 2002-05-15
ATE335826T1 (de) 2006-09-15
JP2003506093A (ja) 2003-02-18
ES2269173T3 (es) 2007-04-01
NO20020633D0 (no) 2002-02-08
CA2379571C (fr) 2011-03-29
HK1047128A1 (en) 2003-02-07
NO328339B1 (no) 2010-02-01
CN1230543C (zh) 2005-12-07
US6936455B1 (en) 2005-08-30
AU6993300A (en) 2001-03-05
SK1852002A3 (en) 2002-07-02
CZ302366B6 (cs) 2011-04-13
KR20020026366A (ko) 2002-04-09
SK287488B6 (sk) 2010-11-08
PL353101A1 (en) 2003-10-20

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