IL142899A0 - Antagonistic analogs of gh-rh inhibiting igf-1 and -ii - Google Patents

Antagonistic analogs of gh-rh inhibiting igf-1 and -ii

Info

Publication number
IL142899A0
IL142899A0 IL14289999A IL14289999A IL142899A0 IL 142899 A0 IL142899 A0 IL 142899A0 IL 14289999 A IL14289999 A IL 14289999A IL 14289999 A IL14289999 A IL 14289999A IL 142899 A0 IL142899 A0 IL 142899A0
Authority
IL
Israel
Prior art keywords
inhibiting igf
antagonistic analogs
antagonistic
analogs
igf
Prior art date
Application number
IL14289999A
Other languages
English (en)
Original Assignee
Univ Tulane
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Tulane filed Critical Univ Tulane
Publication of IL142899A0 publication Critical patent/IL142899A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IL14289999A 1998-11-25 1999-11-23 Antagonistic analogs of gh-rh inhibiting igf-1 and -ii IL142899A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/199,381 US6057422A (en) 1998-11-25 1998-11-25 Antagonistic analogs of GH-RH inhibiting IGF-I and -II
PCT/US1999/027822 WO2000031136A1 (en) 1998-11-25 1999-11-23 Antagonistic analogs of gh-rh inhibiting igf-i and -ii

Publications (1)

Publication Number Publication Date
IL142899A0 true IL142899A0 (en) 2002-04-21

Family

ID=22737273

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14289999A IL142899A0 (en) 1998-11-25 1999-11-23 Antagonistic analogs of gh-rh inhibiting igf-1 and -ii

Country Status (29)

Country Link
US (2) US6057422A (pt)
EP (1) EP1133522B1 (pt)
JP (1) JP2002530432A (pt)
KR (1) KR100629013B1 (pt)
CN (1) CN100422211C (pt)
AR (1) AR022392A1 (pt)
AT (1) ATE332310T1 (pt)
AU (1) AU757222B2 (pt)
BG (1) BG65137B1 (pt)
BR (1) BR9915512A (pt)
CA (1) CA2351665C (pt)
CO (1) CO5180565A1 (pt)
CZ (1) CZ20011794A3 (pt)
DE (1) DE69932255T2 (pt)
DK (1) DK1133522T3 (pt)
ES (1) ES2264279T3 (pt)
HK (1) HK1036461A1 (pt)
HU (1) HUP0105094A3 (pt)
IL (1) IL142899A0 (pt)
NO (1) NO20012489L (pt)
NZ (1) NZ511307A (pt)
PL (1) PL197471B1 (pt)
PT (1) PT1133522E (pt)
RU (1) RU2235099C2 (pt)
SK (1) SK7252001A3 (pt)
TR (1) TR200101492T2 (pt)
TW (1) TW585873B (pt)
UA (1) UA68407C2 (pt)
WO (1) WO2000031136A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2454135A1 (en) * 2001-07-12 2003-01-23 Exelixis, Inc. Gpcs as modifiers of the irrtk and p21 pathways and methods of use
US20040121407A1 (en) * 2002-09-06 2004-06-24 Elixir Pharmaceuticals, Inc. Regulation of the growth hormone/IGF-1 axis
CN1688696A (zh) * 2002-09-18 2005-10-26 蒙特利尔大学医疗中心 Ghrh类似物
TW200517400A (en) * 2003-08-05 2005-06-01 Univ Tulane Antagonistic analogs of GH-RH (2003)
BRPI0910873A2 (pt) * 2008-03-28 2015-10-06 Us Of America Represented By The Dept Of Veterans Affairs análogos antagonistas de gh-rh substituídos nos terminais n e c
US8691942B2 (en) 2008-03-28 2014-04-08 University Of Miami N- and C- terminal substituted antagonistic analogs of GH-RH
JP5728380B2 (ja) 2008-06-12 2015-06-03 シンタクシン リミテッドＳｙｎｔａｘｉｎ Ｌｉｍｉｔｅｄ 神経内分泌疾患の抑制
EP3473643A1 (en) 2008-06-12 2019-04-24 Ipsen Bioinnovation Limited Fusion proteins for use in the treatemnt of cancer
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer
US8227421B2 (en) * 2009-09-17 2012-07-24 University Of Miami Fluorinated GHRH antagonists
EP2699591A4 (en) 2011-04-21 2014-05-07 Theratechnologies Inc ANALOGS OF THE GROWTH HORMONE-RELATED FACTOR (GRF) AND USES THEREOF
US9079974B2 (en) * 2011-12-21 2015-07-14 The University Of Miami GH-RH analogs with potent agonistic effects
EP2934565B1 (en) 2012-12-21 2019-03-13 University of Miami Ghrh agonists for the treatment of ischemic disorders
WO2014100816A2 (en) 2012-12-21 2014-06-26 University Of Miami Ghrh agonists for islet cell transplantation and function and the treatment of diabetes
AU2015346277B2 (en) 2014-11-12 2020-03-26 Centre Hospitalier Universitaire De Liège Treatment of hormonal disorders of growth
AU2020218272A1 (en) 2019-02-08 2021-09-02 United States Government As Represented By The Department Of Veterans Affairs Growth hormone-releasing hormone antagonists and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4659693A (en) * 1984-04-30 1987-04-21 Syntex (U.S.A.) Inc. N,N'-dialkyl substituted guanidino amino acyl residue substituted GRF-analog peptides
AU651976B2 (en) * 1990-05-04 1994-08-11 The Administrators Of The Tulane Eductional Fund Novel synthetic GRF analogs
US5550212A (en) * 1993-12-17 1996-08-27 The Administrators Of The Tulane Educational Fund Analogues of hGH-RH(1-29)NH2 having antagonistic activity
US5942489A (en) * 1996-05-03 1999-08-24 The Administrators Of The Tulane Educational Fund HGH-RH(1-29)NH2 analogues having antagonistic activity

Also Published As

Publication number Publication date
SK7252001A3 (en) 2002-02-05
AR022392A1 (es) 2002-09-04
PT1133522E (pt) 2006-11-30
AU757222B2 (en) 2003-02-06
EP1133522A1 (en) 2001-09-19
HUP0105094A3 (en) 2002-05-28
DE69932255D1 (de) 2006-08-17
DE69932255T2 (de) 2007-05-31
BR9915512A (pt) 2001-08-07
NO20012489L (no) 2001-07-04
NO20012489D0 (no) 2001-05-21
PL197471B1 (pl) 2008-04-30
TW585873B (en) 2004-05-01
CA2351665A1 (en) 2000-06-02
CN100422211C (zh) 2008-10-01
US7026281B1 (en) 2006-04-11
WO2000031136A9 (en) 2001-07-19
TR200101492T2 (tr) 2001-11-21
CN1328570A (zh) 2001-12-26
AU2029100A (en) 2000-06-13
DK1133522T3 (da) 2006-11-06
WO2000031136A1 (en) 2000-06-02
ATE332310T1 (de) 2006-07-15
EP1133522B1 (en) 2006-07-05
UA68407C2 (en) 2004-08-16
CA2351665C (en) 2008-09-02
KR100629013B1 (ko) 2006-09-26
BG65137B1 (bg) 2007-03-30
CZ20011794A3 (cs) 2002-02-13
HK1036461A1 (en) 2002-01-04
KR20010101079A (ko) 2001-11-14
BG105638A (en) 2002-01-31
ES2264279T3 (es) 2006-12-16
CO5180565A1 (es) 2002-07-30
JP2002530432A (ja) 2002-09-17
RU2235099C2 (ru) 2004-08-27
US6057422A (en) 2000-05-02
HUP0105094A2 (hu) 2002-04-29
NZ511307A (en) 2005-01-28
PL349877A1 (en) 2002-09-23

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees