IL137808A0 - Erythropoietin liposomal dispersion - Google Patents

Erythropoietin liposomal dispersion

Info

Publication number
IL137808A0
IL137808A0 IL13780899A IL13780899A IL137808A0 IL 137808 A0 IL137808 A0 IL 137808A0 IL 13780899 A IL13780899 A IL 13780899A IL 13780899 A IL13780899 A IL 13780899A IL 137808 A0 IL137808 A0 IL 137808A0
Authority
IL
Israel
Prior art keywords
erythropoietin
cholesterol
cholesterols
lecithin
liposome based
Prior art date
Application number
IL13780899A
Other languages
English (en)
Original Assignee
Cilag Ag Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cilag Ag Int filed Critical Cilag Ag Int
Publication of IL137808A0 publication Critical patent/IL137808A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1816—Erythropoietin [EPO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
IL13780899A 1998-02-23 1999-02-12 Erythropoietin liposomal dispersion IL137808A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98103111A EP0937456B1 (fr) 1998-02-23 1998-02-23 Dispersion liposomale d'érythropoietine
PCT/IB1999/000249 WO1999042085A1 (fr) 1998-02-23 1999-02-12 Dispersion liposomale d'erythropoietine

Publications (1)

Publication Number Publication Date
IL137808A0 true IL137808A0 (en) 2001-10-31

Family

ID=8231466

Family Applications (2)

Application Number Title Priority Date Filing Date
IL13780899A IL137808A0 (en) 1998-02-23 1999-02-12 Erythropoietin liposomal dispersion
IL137808A IL137808A (en) 1998-02-23 2000-08-10 Dispersion of erythropoietin as chelosomes

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL137808A IL137808A (en) 1998-02-23 2000-08-10 Dispersion of erythropoietin as chelosomes

Country Status (23)

Country Link
US (2) US6645522B2 (fr)
EP (1) EP0937456B1 (fr)
JP (1) JP4613294B2 (fr)
KR (1) KR100591871B1 (fr)
CN (1) CN1184958C (fr)
AT (1) ATE271376T1 (fr)
AU (1) AU750481B2 (fr)
BR (1) BR9908202A (fr)
CA (1) CA2320072C (fr)
CZ (1) CZ296415B6 (fr)
DE (1) DE69825137T2 (fr)
DK (1) DK0937456T3 (fr)
ES (1) ES2224299T3 (fr)
HU (1) HUP0101026A2 (fr)
IL (2) IL137808A0 (fr)
NO (1) NO20004186D0 (fr)
NZ (1) NZ506429A (fr)
PL (1) PL194502B1 (fr)
PT (1) PT937456E (fr)
RU (1) RU2218914C2 (fr)
SI (1) SI0937456T1 (fr)
SK (1) SK284036B6 (fr)
WO (1) WO1999042085A1 (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2224299T3 (es) * 1998-02-23 2005-03-01 Cilag Ag International Dispersion liposomal de eritroyetina.
US7345019B1 (en) * 1999-04-13 2008-03-18 The Kenneth S. Warren Institute, Inc. Modulation of excitable tissue function by peripherally administered erythropoietin
ES2280170T3 (es) * 1999-12-22 2007-09-16 Dade Behring Marburg Gmbh Soluciones de procalcitonina humana.
US20030072737A1 (en) 2000-12-29 2003-04-17 Michael Brines Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs
US7767643B2 (en) 2000-12-29 2010-08-03 The Kenneth S. Warren Institute, Inc. Protection, restoration, and enhancement of erythropoietin-responsive cells, tissues and organs
DE10219545A1 (de) * 2002-04-26 2003-11-06 Lang Florian Regulation der Apoptose
DE60332358D1 (de) * 2002-09-09 2010-06-10 Hanall Pharmaceutical Co Ltd Protease-resistente modifizierte interferon alpha polypeptide
JP2004115397A (ja) * 2002-09-25 2004-04-15 Fuji Photo Film Co Ltd 血管疾患治療薬を含むリポソーム
ES2255467T3 (es) * 2003-02-07 2009-05-01 Prometic Biosciences Inc. Acidos grasos de cadena de longitud media, gliceridos y analogos como estimuladores de eritropoyesis.
KR101154442B1 (ko) * 2003-07-17 2012-06-15 오츠카 세이야쿠 가부시키가이샤 배당체 함유 리포솜
EA010650B1 (ru) * 2003-09-29 2008-10-30 Уоррен Фармасьютикалз, Инк. Защищающие ткань цитокины для лечения и профилактики сепсиса и образования спаек
EP1537876A1 (fr) * 2003-12-01 2005-06-08 BioGeneriX AG Formulation d'une solution d'érythropoiétine
DE602005018473D1 (de) * 2004-05-24 2010-02-04 Polymun Scient Immunbio Forsch Superbeladene liposome für die arzneimittelabgabe
KR100684380B1 (ko) 2005-05-24 2007-02-20 한국화학연구원 빗살형 폴리에틸렌글리콜을 결합한 리포솜 및 이의 제조방법
US9119782B2 (en) * 2006-03-20 2015-09-01 Mary P. McCourt Drug delivery means
EP2120998B1 (fr) 2006-11-28 2013-08-07 HanAll Biopharma Co., Ltd. Polypeptides d'érythropoïétine modifiés et utilisation de ceux-ci dans des traitements
WO2009044406A2 (fr) * 2007-05-09 2009-04-09 Claris Lifesciences Limited Vésicules unilamellaires stabilisées de façon stéarique, procédé de préparation et utilisation
US20100003322A1 (en) * 2008-07-03 2010-01-07 Lai Felix S Enteric coated hydrophobic matrix formulation
US20110070294A1 (en) * 2009-09-23 2011-03-24 Javeri Indu Methods for the Administration of Drugs Using Liposomes
JP6189749B2 (ja) * 2010-06-23 2017-08-30 ブライトサイド イノベーションズ，インコーポレイティド レシチン担体小胞とその作製方法
EA018472B1 (ru) * 2010-09-15 2013-08-30 Открытое Акционерное Общество "Протек" Частицы, содержащие эритропоэтин, для лечения и профилактики неврологических и гематологических заболеваний и нарушений
JP2016513712A (ja) 2013-03-14 2016-05-16 ジェローム， ジェイ． シェンターク， カイロミクロンへの分子の取り込みのためのコレストソーム小胞
CN108066288A (zh) * 2014-01-03 2018-05-25 广州市鼍龙生物技术开发有限公司 一种鳄鱼油纳米脂质体及其制备方法
DK3138556T3 (da) * 2014-04-30 2022-04-11 Fujifilm Corp Fremgangsmåde til fremstilling af liposomer
US11198831B2 (en) 2019-01-31 2021-12-14 Kvi Llc Lubricant for a device

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ210501A (en) 1983-12-13 1991-08-27 Kirin Amgen Inc Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence
JPS6197229A (ja) * 1984-10-18 1986-05-15 Chugai Pharmaceut Co Ltd 安定なエリトロポエチン製剤
AU598002B2 (en) * 1986-07-15 1990-06-14 Cilag Ltd. Method of preparing single bilayered liposomes
JPH087219B2 (ja) 1992-04-27 1996-01-29 雪印乳業株式会社 リポソーム封入生理活性蛋白質の定量方法
JPH06228012A (ja) 1993-01-29 1994-08-16 Dai Ichi Seiyaku Co Ltd リポソーム製剤
CA2120197A1 (fr) * 1993-04-02 1994-10-03 Kenji Endo Dispersions aqueuses stables renfermant des liposomes
US5874075A (en) * 1993-10-06 1999-02-23 Amgen Inc. Stable protein: phospholipid compositions and methods
US6214388B1 (en) * 1994-11-09 2001-04-10 The Regents Of The University Of California Immunoliposomes that optimize internalization into target cells
JP3850468B2 (ja) * 1994-12-28 2006-11-29 中外製薬株式会社 エリスロポエチンのリポソーム製剤
US5858397A (en) * 1995-10-11 1999-01-12 University Of British Columbia Liposomal formulations of mitoxantrone
ES2224299T3 (es) * 1998-02-23 2005-03-01 Cilag Ag International Dispersion liposomal de eritroyetina.

Also Published As

Publication number Publication date
PT937456E (pt) 2004-10-29
CA2320072C (fr) 2009-04-07
US20040052838A1 (en) 2004-03-18
CN1298296A (zh) 2001-06-06
DE69825137T2 (de) 2005-07-21
AU750481B2 (en) 2002-07-18
BR9908202A (pt) 2000-10-24
JP4613294B2 (ja) 2011-01-12
SK284036B6 (sk) 2004-08-03
DK0937456T3 (da) 2004-11-08
AU2180899A (en) 1999-09-06
CN1184958C (zh) 2005-01-19
JP2002503685A (ja) 2002-02-05
PL194502B1 (pl) 2007-06-29
IL137808A (en) 2007-07-24
ATE271376T1 (de) 2004-08-15
RU2218914C2 (ru) 2003-12-20
NZ506429A (en) 2003-03-28
US20020028236A1 (en) 2002-03-07
WO1999042085A1 (fr) 1999-08-26
ES2224299T3 (es) 2005-03-01
NO20004186L (no) 2000-08-22
CA2320072A1 (fr) 1999-08-26
SI0937456T1 (en) 2004-12-31
SK12222000A3 (sk) 2001-11-06
DE69825137D1 (de) 2004-08-26
EP0937456A1 (fr) 1999-08-25
KR20010041152A (ko) 2001-05-15
PL342514A1 (en) 2001-06-18
US6645522B2 (en) 2003-11-11
HUP0101026A2 (hu) 2001-08-28
CZ20002959A3 (cs) 2001-10-17
KR100591871B1 (ko) 2006-06-23
CZ296415B6 (cs) 2006-03-15
EP0937456B1 (fr) 2004-07-21
NO20004186D0 (no) 2000-08-22

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