IL134392A0 - Vaccine against hpv - Google Patents
Vaccine against hpvInfo
- Publication number
- IL134392A0 IL134392A0 IL13439298A IL13439298A IL134392A0 IL 134392 A0 IL134392 A0 IL 134392A0 IL 13439298 A IL13439298 A IL 13439298A IL 13439298 A IL13439298 A IL 13439298A IL 134392 A0 IL134392 A0 IL 134392A0
- Authority
- IL
- Israel
- Prior art keywords
- protein
- vaccine against
- against hpv
- relates
- human
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 102000004169 proteins and genes Human genes 0.000 abstract 4
- 102100037840 Dehydrogenase/reductase SDR family member 2, mitochondrial Human genes 0.000 abstract 1
- 241000606768 Haemophilus influenzae Species 0.000 abstract 1
- 241000701806 Human papillomavirus Species 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 101710188053 Protein D Proteins 0.000 abstract 1
- 101710132893 Resolvase Proteins 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000004927 fusion Effects 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 208000037798 influenza B Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 208000003154 papilloma Diseases 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9717953.5A GB9717953D0 (en) | 1997-08-22 | 1997-08-22 | Vaccine |
PCT/EP1998/005285 WO1999010375A2 (fr) | 1997-08-22 | 1998-08-17 | Vaccin |
Publications (1)
Publication Number | Publication Date |
---|---|
IL134392A0 true IL134392A0 (en) | 2001-04-30 |
Family
ID=10817971
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13439298A IL134392A0 (en) | 1997-08-22 | 1998-08-17 | Vaccine against hpv |
Country Status (23)
Country | Link |
---|---|
US (2) | US6342224B1 (fr) |
EP (1) | EP1007551B1 (fr) |
JP (1) | JP2001513986A (fr) |
KR (1) | KR20010023193A (fr) |
CN (1) | CN1276833A (fr) |
AT (1) | ATE267211T1 (fr) |
AU (1) | AU732946B2 (fr) |
BR (1) | BR9812139A (fr) |
CA (1) | CA2301920C (fr) |
CO (1) | CO4810234A1 (fr) |
DE (1) | DE69824013T2 (fr) |
ES (1) | ES2221198T3 (fr) |
GB (1) | GB9717953D0 (fr) |
HU (1) | HUP0004327A3 (fr) |
IL (1) | IL134392A0 (fr) |
MA (1) | MA24638A1 (fr) |
NO (1) | NO20000850L (fr) |
NZ (1) | NZ502632A (fr) |
PL (1) | PL339009A1 (fr) |
TR (1) | TR200000480T2 (fr) |
UY (1) | UY25146A1 (fr) |
WO (1) | WO1999010375A2 (fr) |
ZA (1) | ZA987591B (fr) |
Families Citing this family (90)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9706957D0 (en) | 1997-04-05 | 1997-05-21 | Smithkline Beecham Plc | Formulation |
IL135776A0 (en) * | 1997-10-24 | 2001-05-20 | Life Technologies Inc | Recombinational cloning using nucleic acids having recombination sites |
GB9820525D0 (en) | 1998-09-21 | 1998-11-11 | Allergy Therapeutics Ltd | Formulation |
EP1502602A3 (fr) * | 1998-10-05 | 2006-05-17 | Pharmexa A/S | Procedes de vaccination therapeutique |
MXPA01003503A (es) | 1998-10-05 | 2005-01-14 | Pharmexa As | Nuevos metodos terapeuticos de vacunacion. |
EP2266604A3 (fr) | 1998-10-16 | 2011-05-11 | GlaxoSmithKline Biologicals S.A. | Produits adjuvants et vaccins |
MXPA01011499A (es) * | 1999-05-13 | 2002-06-04 | American Cyanamid Co | Formulaciones de combinacion de adyuvantes. |
GB9921146D0 (en) * | 1999-09-07 | 1999-11-10 | Smithkline Beecham Biolog | Novel composition |
GB0000891D0 (en) | 2000-01-14 | 2000-03-08 | Allergy Therapeutics Ltd | Formulation |
US7015033B1 (en) | 2000-05-25 | 2006-03-21 | Aventis Pasteur Limited | Co-expression of recombination proteins |
EP1294905A1 (fr) * | 2000-06-26 | 2003-03-26 | SmithKline Beecham Biologics SA | Proteines hybrides triples contenant de l'ubiquitine fusionnee entre une thioredoxine et un polypeptide d'interet |
US7198924B2 (en) | 2000-12-11 | 2007-04-03 | Invitrogen Corporation | Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites |
ES2284559T3 (es) | 2001-03-23 | 2007-11-16 | Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechts | Genes y proteinas e6 y e7 modificados del vph utiles como vacuna. |
AU2002340662B2 (en) * | 2001-11-07 | 2008-07-03 | Tekmira Pharmaceuticals Corporation | Mucosal adjuvants comprising an oligonucleotide and a cationic lipid |
US6861410B1 (en) * | 2002-03-21 | 2005-03-01 | Chiron Corporation | Immunological adjuvant compositions |
FR2839072A1 (fr) | 2002-04-24 | 2003-10-31 | Neovacs | Produit d'expression d'un adn codant une proteine e7 mutee de hpv-16, composition immunogene contenant ledit produit d'expression et son procede de preparation |
FR2839080B1 (fr) * | 2003-04-03 | 2007-09-28 | Neovacs | Procede de preparation d'un produit d'expression d'un adn codant une proteine e7 mutee de hpv-16, par des cellules de la levure pichia pastoris |
US20040013649A1 (en) * | 2002-05-10 | 2004-01-22 | Inex Pharmaceuticals Corporation | Cancer vaccines and methods of using the same |
US20040009944A1 (en) * | 2002-05-10 | 2004-01-15 | Inex Pharmaceuticals Corporation | Methylated immunostimulatory oligonucleotides and methods of using the same |
EP1543128A4 (fr) * | 2002-07-18 | 2008-02-20 | Invitrogen Corp | Vecteurs viraux contenant des sites de recombinaison |
EP2255826B1 (fr) | 2002-08-02 | 2016-04-13 | GlaxoSmithKline Biologicals S.A. | Composition vaccinale comprenant une combinaison d'antigenes de neisseria |
TW200407162A (en) * | 2002-08-30 | 2004-05-16 | Glaxo Group Ltd | Vaccine |
CN1720060B (zh) * | 2002-10-03 | 2011-12-14 | 惠氏控股公司 | 人乳头瘤病毒多肽和免疫原性组合物 |
LT2395073T (lt) | 2002-11-01 | 2017-11-10 | Glaxosmithkline Biologicals S.A. | Džiovinimo būdas |
ES2451620T3 (es) * | 2002-11-07 | 2014-03-28 | Synergy America, Inc. | Composiciones y métodos destinados a tratar o prevenir la infección neumocócica |
CN100506999C (zh) * | 2003-03-24 | 2009-07-01 | 麦克公司 | Hpv31l1在酵母中的优化表达 |
CZ297389B6 (cs) * | 2003-07-03 | 2006-11-15 | Ústav Molekulární Biologie Rostlin Av Cr | Fúzní protein pro vakcinaci proti lidskému papillomaviru a zpusob jeho produkce |
EP1667712B1 (fr) | 2003-10-02 | 2010-07-21 | GlaxoSmithKline Biologicals S.A. | Antigenes de b. pertussis et leur utilisation dans la vaccination |
DE602004027538D1 (de) * | 2003-12-01 | 2010-07-15 | Life Technologies Corp | Rekombinationsstellen enthaltende nukleinsäuremoleküle und verfahren zur verwendung davon |
WO2005089164A2 (fr) * | 2003-12-31 | 2005-09-29 | Pharmexa Inc. | Induction de reponses immunitaires cellulaires au papillomavirus humain utilisant des compositions peptidiques et d'acides nucleiques |
US10941353B2 (en) * | 2004-04-28 | 2021-03-09 | Hydrocarbon Technology & Innovation, Llc | Methods and mixing systems for introducing catalyst precursor into heavy oil feedstock |
ES2662605T3 (es) * | 2004-04-28 | 2018-04-09 | Hydrocarbon Technology & Innovation, Llc | Procedimientos y sistemas de hidroprocesamiento de lecho fijo y procedimientos para la mejora de un sistema de lecho fijo existente |
CA2855431C (fr) | 2004-04-28 | 2016-08-16 | Headwaters Heavy Oil, Llc | Procedes et systemes d'hydrotraitement a lit bouillonnant et procedes d'amelioration d'un systeme a lit bouillonnant existant |
GB0427131D0 (en) * | 2004-12-10 | 2005-01-12 | Glaxosmithkline Biolog Sa | Novel combination |
GB0505996D0 (en) | 2005-03-23 | 2005-04-27 | Glaxosmithkline Biolog Sa | Fermentation process |
PE20110072A1 (es) | 2005-06-27 | 2011-02-04 | Glaxosmithkline Biolog Sa | Composicion inmunogenica |
US7732166B2 (en) * | 2005-11-15 | 2010-06-08 | Oncohealth Corporation | Detection method for human pappilomavirus (HPV) and its application in cervical cancer |
TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
EP2049559B1 (fr) | 2006-07-28 | 2012-12-19 | The Trustees of the University of Pennsylvania | Vaccins hpv améliorés |
AU2007292253A1 (en) * | 2006-09-08 | 2008-03-13 | Wyeth | Arginine wash in protein purification using affinity chromatography |
PT2468300T (pt) | 2006-09-26 | 2018-01-30 | Infectious Disease Res Inst | Composição para vacina contendo adjuvante sintético |
DK2086582T3 (da) | 2006-10-12 | 2013-02-04 | Glaxosmithkline Biolog Sa | Vaccine omfattende en olie-i-vand-emulsionsadjuvans |
PL2086582T3 (pl) | 2006-10-12 | 2013-04-30 | Glaxosmithkline Biologicals Sa | Kompozycja zawierająca adiuwant w postaci emulsji typu olej w wodzie |
US8859218B2 (en) | 2008-06-13 | 2014-10-14 | Oncohealth Corp. | In situ detection of early stages and late stages HPV infection |
US8968995B2 (en) | 2008-11-12 | 2015-03-03 | Oncohealth Corp. | Detection, screening, and diagnosis of HPV-associated cancers |
CA2674552A1 (fr) * | 2007-01-15 | 2008-07-24 | Glaxosmithkline Biologicals S.A. | Vaccin |
US8034232B2 (en) * | 2007-10-31 | 2011-10-11 | Headwaters Technology Innovation, Llc | Methods for increasing catalyst concentration in heavy oil and/or coal resid hydrocracker |
US8466259B2 (en) | 2007-12-07 | 2013-06-18 | National Health Research Institutes | Adjuvants |
US8426163B2 (en) | 2007-12-07 | 2013-04-23 | National Health Research Institutes | Production of lipidated proteins in E. coli |
US8142645B2 (en) * | 2008-01-03 | 2012-03-27 | Headwaters Technology Innovation, Llc | Process for increasing the mono-aromatic content of polynuclear-aromatic-containing feedstocks |
ES2622562T3 (es) | 2008-12-09 | 2017-07-06 | Pfizer Vaccines Llc | Vacuna de péptido CH3 de IgE |
CA2653478A1 (fr) * | 2009-01-23 | 2010-07-23 | Gregg Martin | Lave-vehicules industriels |
CN102449479B (zh) | 2009-05-07 | 2015-11-25 | 安科健康公司 | 鉴别高度或≥cin2用于人乳头瘤病毒(hpv)与hpv相关癌症的早期及晚期检测、筛检和诊断 |
US8287880B2 (en) | 2009-06-02 | 2012-10-16 | National Health Research Institutes | Lipidated vaccine against dengue virus infection |
DK2437753T3 (en) | 2009-06-05 | 2016-12-19 | Infectious Disease Res Inst | Synthetic glucopyranosyl lipid adjuvants and vaccine compositions containing them |
CN102482327B (zh) * | 2009-06-22 | 2014-10-29 | 财团法人卫生研究院 | 脂质化肿瘤相关抗原及其免疫治疗的组成物及方法 |
JP2013500326A (ja) | 2009-07-30 | 2013-01-07 | ファイザー バクシーンズ エルエルシー | 抗原性タウペプチドおよびその使用 |
AR074485A1 (es) * | 2009-12-04 | 2011-01-19 | Consejo Nac Invest Cient Tec | Vacuna contra lesiones neoplasicas o cancerosas causadas por el virus del papiloma humano (vph), procedimientos, usos y metodos |
WO2011084598A1 (fr) | 2010-01-08 | 2011-07-14 | Oncohealth Corporation | Immunoessais sur le vph à base de cellule et à haut débit pour diagnostiquer et dépister des cancers associés au vph |
CN103002910A (zh) | 2010-03-10 | 2013-03-27 | 葛兰素史密丝克莱恩生物有限公司 | 疫苗组合物 |
WO2011154878A1 (fr) | 2010-06-07 | 2011-12-15 | Pfizer Vaccines Llc | Vaccin peptidique ige ch3 |
WO2012020871A1 (fr) | 2010-08-13 | 2012-02-16 | 주식회사 제넥신 | Composition contenant un plasmode du papillomavirus humain et un promoteur d'immunité destinée à prévenir ou traiter le cancer du col de l'utérus |
GB201015132D0 (en) | 2010-09-10 | 2010-10-27 | Univ Bristol | Vaccine composition |
TWI507413B (zh) | 2010-11-15 | 2015-11-11 | Nat Health Research Institutes | 脂質化多抗原表位疫苗 |
TW201221642A (en) | 2010-11-15 | 2012-06-01 | Nat Health Research Institutes | Method of producing lipidated polypeptides |
CA2832307A1 (fr) | 2011-04-08 | 2012-10-18 | Immune Design Corp. | Compositions immunogenes et leurs procedes d'utilisation pour induire des reponses immunitaires humorales et cellulaires |
US9790440B2 (en) | 2011-09-23 | 2017-10-17 | Headwaters Technology Innovation Group, Inc. | Methods for increasing catalyst concentration in heavy oil and/or coal resid hydrocracker |
ES2646590T3 (es) * | 2012-01-24 | 2017-12-14 | Sanford Health | Polinucleótidos para el tratamiento de tumores positivos para polipéptidos víricos oncogénicos |
US11510875B2 (en) | 2012-02-07 | 2022-11-29 | Access To Advanced Health Institute | Adjuvant formulations comprising TLR4 agonists and methods of using the same |
EP2850431B1 (fr) | 2012-05-16 | 2018-04-18 | Immune Design Corp. | Vaccins contre le hsv-2 |
US9644157B2 (en) | 2012-07-30 | 2017-05-09 | Headwaters Heavy Oil, Llc | Methods and systems for upgrading heavy oil using catalytic hydrocracking and thermal coking |
WO2014165291A1 (fr) | 2013-03-12 | 2014-10-09 | The Trustees Of The University Of Pennsylvania | Vaccins améliorés pour le papilloma virus humain et leurs procédés d'utilisation |
CA2909221A1 (fr) | 2013-04-18 | 2014-10-23 | Immune Design Corp. | Monotherapie par gla pour une utilisation dans le traitement du cancer |
US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
KR102411781B1 (ko) | 2013-12-31 | 2022-06-22 | 인펙셔스 디지즈 리서치 인스티튜트 (아이디알아이) | 단일 바이알 백신 제형 |
CN103772508B (zh) * | 2014-01-15 | 2017-05-10 | 深圳泰来生物医药有限公司 | 免疫增强的人乳头瘤病毒感染及相关疾病的治疗性疫苗 |
EP3193905B1 (fr) | 2014-08-15 | 2024-04-03 | Genexine, Inc. | Compositions pour utilisation dans le traitement du cancer du col de l'utérus |
CA2963148C (fr) | 2014-10-28 | 2024-04-30 | Agrivida, Inc. | Procedes et compositions de stabilisation de proteases de trans-epissage modifiee par inteine |
WO2016090540A1 (fr) * | 2014-12-08 | 2016-06-16 | 刘日廷 | Peptide à motif minimal d'épitope d'antigène dans les protéines e6 et e7 oncogènes du virus du papillome humain (hpv) de type 18 |
JP5973007B2 (ja) * | 2015-01-30 | 2016-08-17 | ジェネクサイン・インコーポレーテッド | ヒトパピローマウイルス変形体及び免疫増強剤を含む子宮頸癌の予防または治療用組成物 |
US11414607B2 (en) | 2015-09-22 | 2022-08-16 | Hydrocarbon Technology & Innovation, Llc | Upgraded ebullated bed reactor with increased production rate of converted products |
US11414608B2 (en) | 2015-09-22 | 2022-08-16 | Hydrocarbon Technology & Innovation, Llc | Upgraded ebullated bed reactor used with opportunity feedstocks |
TWI670280B (zh) * | 2016-02-23 | 2019-09-01 | 財團法人國家衛生研究院 | 人類乳突病毒之脂質抗原及用於人類乳突病毒相關疾病之免疫治療組合物 |
IL313085A (en) | 2016-05-16 | 2024-07-01 | Access To Advanced Health Inst | Pegylated liposomes and methods of use |
US11421164B2 (en) | 2016-06-08 | 2022-08-23 | Hydrocarbon Technology & Innovation, Llc | Dual catalyst system for ebullated bed upgrading to produce improved quality vacuum residue product |
US11118119B2 (en) | 2017-03-02 | 2021-09-14 | Hydrocarbon Technology & Innovation, Llc | Upgraded ebullated bed reactor with less fouling sediment |
US11732203B2 (en) | 2017-03-02 | 2023-08-22 | Hydrocarbon Technology & Innovation, Llc | Ebullated bed reactor upgraded to produce sediment that causes less equipment fouling |
CA3067224A1 (fr) | 2017-06-15 | 2018-12-20 | Infectious Disease Research Institute | Supports lipidiques nanostructures et emulsions stables et leurs utilisations |
CA3057131C (fr) | 2018-10-17 | 2024-04-23 | Hydrocarbon Technology And Innovation, Llc | Reacteur a lit bouillonnant ameliore sans accumulation liee au recyclage d'asphaltenes dans des residus de tour sous vide |
US11883479B2 (en) | 2020-04-24 | 2024-01-30 | Genexine, Inc. | Method for treating cervical cancer |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2586428B1 (fr) * | 1985-08-26 | 1988-11-25 | Pasteur Institut | Polypeptides et anticorps, caracteristiques du papillomavirus et leurs applications au diagnostic in vitro, a la prevention et/ou la lutte contre des infections a papillomavirus |
DE3907721A1 (de) * | 1989-03-10 | 1990-09-20 | Behringwerke Ag | Immunogene regionen auf dem e7-protein des humanen papillomvierus typ 16 |
DE4015044A1 (de) * | 1990-05-10 | 1991-11-14 | Behringwerke Ag | Seroreaktive epitope auf proteinen des menschlichen papillomavirus (hpv) 18 |
AU8762991A (en) | 1990-09-26 | 1992-04-15 | Bristol-Myers Squibb Company | Human papilloma viral protein expression for use in vaccine compositions |
IL105554A (en) * | 1992-05-05 | 1999-08-17 | Univ Leiden | Peptides of human papillomavirus for use in preparations elicit a human T cell response |
US5869445A (en) * | 1993-03-17 | 1999-02-09 | University Of Washington | Methods for eliciting or enhancing reactivity to HER-2/neu protein |
DE4441197C1 (de) * | 1994-11-18 | 1996-03-28 | Deutsches Krebsforsch | Expressionsplasmide für Hefe |
AUPN015794A0 (en) * | 1994-12-20 | 1995-01-19 | Csl Limited | Variants of human papilloma virus antigens |
WO1996026277A1 (fr) * | 1995-02-24 | 1996-08-29 | Cantab Pharmaceuticals Research Limited | Polypeptides utiles comme agents immunotherapeutiques et procedes de preparation de polypeptides |
US5843752A (en) * | 1995-05-12 | 1998-12-01 | Schering Corporation | Soluble active hepatitis C virus protease |
US6224870B1 (en) * | 1997-01-24 | 2001-05-01 | Genitrix, Ltd. | Vaccine compositions and methods of modulating immune responses |
US5958750A (en) * | 1996-07-03 | 1999-09-28 | Inctye Pharmaceuticals, Inc. | Human hyaluronidase |
-
1997
- 1997-08-22 GB GBGB9717953.5A patent/GB9717953D0/en active Pending
-
1998
- 1998-08-17 BR BR9812139-1A patent/BR9812139A/pt not_active IP Right Cessation
- 1998-08-17 ES ES98945269T patent/ES2221198T3/es not_active Expired - Lifetime
- 1998-08-17 PL PL98339009A patent/PL339009A1/xx not_active Application Discontinuation
- 1998-08-17 CN CN98810251A patent/CN1276833A/zh active Pending
- 1998-08-17 DE DE69824013T patent/DE69824013T2/de not_active Expired - Lifetime
- 1998-08-17 AU AU92639/98A patent/AU732946B2/en not_active Ceased
- 1998-08-17 IL IL13439298A patent/IL134392A0/xx unknown
- 1998-08-17 US US09/485,885 patent/US6342224B1/en not_active Expired - Lifetime
- 1998-08-17 WO PCT/EP1998/005285 patent/WO1999010375A2/fr active IP Right Grant
- 1998-08-17 TR TR2000/00480T patent/TR200000480T2/xx unknown
- 1998-08-17 EP EP98945269A patent/EP1007551B1/fr not_active Expired - Lifetime
- 1998-08-17 NZ NZ502632A patent/NZ502632A/en unknown
- 1998-08-17 JP JP2000507701A patent/JP2001513986A/ja active Pending
- 1998-08-17 KR KR1020007001821A patent/KR20010023193A/ko not_active Application Discontinuation
- 1998-08-17 HU HU0004327A patent/HUP0004327A3/hu unknown
- 1998-08-17 CA CA2301920A patent/CA2301920C/fr not_active Expired - Fee Related
- 1998-08-17 AT AT98945269T patent/ATE267211T1/de not_active IP Right Cessation
- 1998-08-19 UY UY25146A patent/UY25146A1/es not_active Application Discontinuation
- 1998-08-20 CO CO98047511A patent/CO4810234A1/es unknown
- 1998-08-21 ZA ZA9807591A patent/ZA987591B/xx unknown
- 1998-08-21 MA MA25223A patent/MA24638A1/fr unknown
-
2000
- 2000-02-21 NO NO20000850A patent/NO20000850L/no not_active Application Discontinuation
-
2001
- 2001-11-01 US US10/000,903 patent/US20020182221A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1007551A2 (fr) | 2000-06-14 |
EP1007551B1 (fr) | 2004-05-19 |
CA2301920C (fr) | 2011-01-04 |
ATE267211T1 (de) | 2004-06-15 |
PL339009A1 (en) | 2000-12-04 |
WO1999010375A2 (fr) | 1999-03-04 |
TR200000480T2 (tr) | 2000-07-21 |
KR20010023193A (ko) | 2001-03-26 |
MA24638A1 (fr) | 1999-04-01 |
NO20000850L (no) | 2000-04-14 |
DE69824013D1 (de) | 2004-06-24 |
NZ502632A (en) | 2002-03-28 |
CN1276833A (zh) | 2000-12-13 |
CA2301920A1 (fr) | 1999-03-04 |
ES2221198T3 (es) | 2004-12-16 |
JP2001513986A (ja) | 2001-09-11 |
HUP0004327A3 (en) | 2003-08-28 |
HUP0004327A1 (en) | 2001-03-28 |
AU9263998A (en) | 1999-03-16 |
US20020182221A1 (en) | 2002-12-05 |
NO20000850D0 (no) | 2000-02-21 |
GB9717953D0 (en) | 1997-10-29 |
WO1999010375A3 (fr) | 1999-06-10 |
UY25146A1 (es) | 2000-12-29 |
AU732946B2 (en) | 2001-05-03 |
ZA987591B (en) | 2000-02-21 |
CO4810234A1 (es) | 1999-06-30 |
BR9812139A (pt) | 2000-07-18 |
US6342224B1 (en) | 2002-01-29 |
DE69824013T2 (de) | 2005-06-02 |
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