HUP9904137A2 - Immunterápiás szerként hasznosítható polipeptidek és eljárások a polipeptidek előállítására - Google Patents

Immunterápiás szerként hasznosítható polipeptidek és eljárások a polipeptidek előállítására

Info

Publication number
HUP9904137A2
HUP9904137A2 HU9904137A HUP9904137A HUP9904137A2 HU P9904137 A2 HUP9904137 A2 HU P9904137A2 HU 9904137 A HU9904137 A HU 9904137A HU P9904137 A HUP9904137 A HU P9904137A HU P9904137 A2 HUP9904137 A2 HU P9904137A2
Authority
HU
Hungary
Prior art keywords
polypeptides
methods
immunotherapeutic agents
polypeptides useful
polypeptide preparation
Prior art date
Application number
HU9904137A
Other languages
English (en)
Inventor
Jeremy Paddon Carmichael
Stephen Edward Connor
Henry Stephen Thompson
Nigel Richard Whittle
Mark Jonathan Wilson
Original Assignee
Cantab Pharmaceuticals Research Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cantab Pharmaceuticals Research Limited filed Critical Cantab Pharmaceuticals Research Limited
Publication of HUP9904137A2 publication Critical patent/HUP9904137A2/hu
Publication of HUP9904137A3 publication Critical patent/HUP9904137A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

A találmány papillőmavírűs eredetű antigént tartalmazó fúzióspőlipeptidekre és pőlipeptid aggregátűmőkra, ezekből készültkészítményekre és ezeknek példáűl adjűvánsőkkal együtt imműnőgénanyagként és vakcinaként példáűl HPV-specifikűs imműnválaszőkkiváltására történő alkalmazására vőnatkőzik. A pőlipeptidektisztítása sőrán ezeket amőrf aggregátűmőkként, amelyek, ha őldatbanvagy diszperzióban vannak, sterilizáló szűrőn átbőcsáthatók, kapják.Az ilyen pőlipeptidek egyik példája egy fűziőnált prőtein, amely az L2és E7 hűmán papillőmavírűs-prőteinekből jön létre. ŕ
HU9904137A 1996-07-29 1996-07-29 Polypeptides useful as immunotherapeutic agents and methods of polypeptide preparation HUP9904137A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/GB1996/001816 WO1998004706A1 (en) 1996-07-29 1996-07-29 Polypeptides useful as immunotherapeutic agents and methods of polypeptide preparation

Publications (2)

Publication Number Publication Date
HUP9904137A2 true HUP9904137A2 (hu) 2000-04-28
HUP9904137A3 HUP9904137A3 (en) 2001-06-28

Family

ID=10787784

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9904137A HUP9904137A3 (en) 1996-07-29 1996-07-29 Polypeptides useful as immunotherapeutic agents and methods of polypeptide preparation

Country Status (5)

Country Link
CZ (1) CZ28899A3 (hu)
FI (1) FI990157A0 (hu)
HU (1) HUP9904137A3 (hu)
IL (1) IL128269A0 (hu)
WO (1) WO1998004706A1 (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100919266B1 (ko) 2000-06-26 2009-09-30 엔벤타 바이오파마슈티컬스 코포레이션 인간 파필로마 바이러스 치료법
AU2003215244A1 (en) * 2002-02-14 2003-09-04 Curagen Corporation Complexes and methods of using same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992005248A1 (en) * 1990-09-26 1992-04-02 Bristol-Myers Squibb Company Human papilloma viral protein expression for use in vaccine compositions
GB9105383D0 (en) * 1991-03-14 1991-05-01 Immunology Ltd An immunotherapeutic for cervical cancer
US5618536A (en) * 1992-09-03 1997-04-08 The United States Of America As Represented By The Department Of Health And Human Services Chimeric papillomavirus-like particles
JP3958360B2 (ja) * 1995-02-24 2007-08-15 キャンタブ ファーマシューティカルズ リサーチ リミティド 免疫治療剤として役立つポリペプチド及びポリペプチド調製の方法

Also Published As

Publication number Publication date
FI990157A (fi) 1999-01-28
FI990157A0 (fi) 1999-01-28
IL128269A0 (en) 1999-11-30
HUP9904137A3 (en) 2001-06-28
WO1998004706A1 (en) 1998-02-05
CZ28899A3 (cs) 1999-07-14

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