US5702359A
(en)
*
|
1995-06-06 |
1997-12-30 |
Genetronics, Inc. |
Needle electrodes for mediated delivery of drugs and genes
|
US5993434A
(en)
*
|
1993-04-01 |
1999-11-30 |
Genetronics, Inc. |
Method of treatment using electroporation mediated delivery of drugs and genes
|
US6261281B1
(en)
*
|
1997-04-03 |
2001-07-17 |
Electrofect As |
Method for genetic immunization and introduction of molecules into skeletal muscle and immune cells
|
EP0991425B1
(fr)
*
|
1997-06-30 |
2005-03-09 |
Institut Gustave Roussy |
Amelioration du transfert d'acide nucleique dans les cellules d'organismes eucaryotes pluricellulaires et combinaison permettant la mise en oeuvre du procede
|
BR9810369A
(pt)
|
1997-06-30 |
2000-09-05 |
Rhone Poulenc Rorer Sa |
Processo de transferência de ácido nucleico para o interior de um ou mais músculos estriados, in vivo, composição, ácido mucleico e campo elétrico, e, produto de combinação
|
US6241701B1
(en)
|
1997-08-01 |
2001-06-05 |
Genetronics, Inc. |
Apparatus for electroporation mediated delivery of drugs and genes
|
US6055453A
(en)
|
1997-08-01 |
2000-04-25 |
Genetronics, Inc. |
Apparatus for addressing needle array electrodes for electroporation therapy
|
US20040229363A1
(en)
*
|
1998-06-24 |
2004-11-18 |
Ed Nolan |
High efficiency transfection based on low electric field strength, long pulse length
|
EP1100579B1
(en)
|
1998-07-13 |
2015-09-02 |
Inovio Pharmaceuticals, Inc. |
Skin and muscle-targeted gene therapy by pulsed electrical field
|
US6678556B1
(en)
|
1998-07-13 |
2004-01-13 |
Genetronics, Inc. |
Electrical field therapy with reduced histopathological change in muscle
|
US7922709B2
(en)
|
1998-07-13 |
2011-04-12 |
Genetronics, Inc. |
Enhanced delivery of naked DNA to skin by non-invasive in vivo electroporation
|
AU2868200A
(en)
*
|
1999-02-08 |
2000-08-25 |
Chiron Corporation |
Electrically-mediated enhancement of dna vaccine immunity and efficacy in vivo
|
US6593130B1
(en)
|
1999-04-16 |
2003-07-15 |
The Regents Of The University Of California |
Method and apparatus for ex vivo and in vivo cellular electroporation of gene protein or drug therapy
|
BR0108959A
(pt)
*
|
2000-03-03 |
2003-10-14 |
Valentis Inc |
Composições de poloxmero ou poloxamina melhoradas para distribuição de ácido nucléico
|
JP2004532654A
(ja)
|
2000-05-22 |
2004-10-28 |
マーク・アンド・カンパニー・インコーポレイテッド |
薬剤投与システム性能評価システム及び方法
|
US6733485B1
(en)
|
2001-05-25 |
2004-05-11 |
Advanced Bionics Corporation |
Microstimulator-based electrochemotherapy methods and systems
|
US20040204669A1
(en)
*
|
2001-07-05 |
2004-10-14 |
Hofmann Gunter A. |
Apparatus for electroporation mediated delivery for drugs and genes
|
US7713740B2
(en)
*
|
2001-08-24 |
2010-05-11 |
University Of South Florida |
Method of using electric fields to facilitate the entry of molecules into cells in vivo
|
CA2461380C
(en)
|
2001-10-11 |
2011-03-22 |
Merck & Co., Inc. |
Hepatitis c virus vaccine
|
PT1436397E
(pt)
|
2001-10-11 |
2010-07-15 |
Angeletti P Ist Richerche Bio |
Vacina de v�rus da hepatite c
|
US7252819B2
(en)
*
|
2001-11-08 |
2007-08-07 |
The Regents Of The University Of California |
Methods and compositions for correction of cardiac conduction disturbances
|
WO2003051454A2
(en)
*
|
2001-12-14 |
2003-06-26 |
Genetronics, Inc. |
Methods for particle-assisted polynucleotide immunization using a pulsed electric field
|
JP2005527490A
(ja)
*
|
2002-01-18 |
2005-09-15 |
イノヴィオ アーエス |
筋肉内投与のための二重特異性抗体dna構築物
|
US8209006B2
(en)
|
2002-03-07 |
2012-06-26 |
Vgx Pharmaceuticals, Inc. |
Constant current electroporation device and methods of use
|
CA2477872A1
(en)
|
2002-03-07 |
2003-09-18 |
Merck & Co., Inc. |
Clinical syringe with electrical stimulation aspects
|
US7245963B2
(en)
*
|
2002-03-07 |
2007-07-17 |
Advisys, Inc. |
Electrode assembly for constant-current electroporation and use
|
US6912417B1
(en)
|
2002-04-05 |
2005-06-28 |
Ichor Medical Systmes, Inc. |
Method and apparatus for delivery of therapeutic agents
|
DE60322523D1
(de)
|
2002-04-16 |
2008-09-11 |
Cyto Pulse Sciences Inc |
Ien mit übersetzenden elektrischen feldern und elektroden-polaritäts-umkehr
|
US20040106896A1
(en)
*
|
2002-11-29 |
2004-06-03 |
The Regents Of The University Of California |
System and method for forming a non-ablative cardiac conduction block
|
US7328064B2
(en)
|
2002-07-04 |
2008-02-05 |
Inovio As |
Electroporation device and injection apparatus
|
PT1729848E
(pt)
|
2004-03-08 |
2015-08-28 |
Ichor Medical Systems Inc |
Dispositivo melhorado para uma administração electricamente mediada de agentes terapêuticos
|
TW200613554A
(en)
|
2004-06-17 |
2006-05-01 |
Wyeth Corp |
Plasmid having three complete transcriptional units and immunogenic compositions for inducing an immune response to HIV
|
CA2598134A1
(en)
*
|
2005-03-19 |
2006-09-28 |
The Regents Of The University Of California |
Ultra low strength electric field network-mediated ex vivo gene, protein and drug delivery in cells
|
EP2570423B1
(en)
|
2005-06-17 |
2023-05-03 |
MSD Italia S.r.l. |
Hepatitis C virus nucleic acid vaccine
|
AU2007215328A1
(en)
*
|
2006-02-13 |
2007-08-23 |
Oncolytics Biotech Inc. |
Use of local immune suppression to enhance oncolytic viral therapy
|
WO2008063555A2
(en)
|
2006-11-17 |
2008-05-29 |
Genetronics, Inc. |
Methods of enhancing immune response using electroporation-assisted vaccination and boosting
|
EP2612868B1
(en)
|
2007-11-01 |
2018-08-15 |
Astellas Pharma Inc. |
Immunosuppressive polypeptides and nucleic acids
|
US8852609B2
(en)
*
|
2008-04-04 |
2014-10-07 |
The Trustees Of The University Of Pennsylvania |
Consensus sequences of chikungunya viral proteins, nucleic acid molecules encoding the same, and compositions and methods for using the same
|
CA2720168C
(en)
|
2008-04-04 |
2024-04-30 |
David B. Weiner |
Vaccines and immunotherapeutics using il-28 and compositions and methods of using the same
|
EP2147697A1
(en)
|
2008-07-21 |
2010-01-27 |
Centre National De La Recherche Scientifique-CNRS |
Process and device for applying electric fields into conductive material
|
EP2156860A1
(en)
|
2008-08-20 |
2010-02-24 |
Centre National De La Recherche Scientifique-CNRS |
Method for producing insulated electrodes for applying electric fields into conductive material
|
US20100298697A1
(en)
*
|
2009-05-19 |
2010-11-25 |
Medtronic, Inc. |
Method and devices for improved efficiency of rna delivery to cells
|
US8207138B2
(en)
|
2009-05-19 |
2012-06-26 |
Medtronic, Inc. |
Methods and devices for improved efficiency of RNA delivery to cells
|
KR20120093163A
(ko)
|
2009-09-14 |
2012-08-22 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
Il-15 수용체 알파 및/또는 이를 인코딩하는 핵산 분자를 포함하는 백신 및 면역 치료제, 및 이를 이용하는 방법
|
KR102138780B1
(ko)
|
2009-11-02 |
2020-07-29 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
구제역 바이러스(fmdv) 공통 단백질, 이를 위한 코딩 서열 및 이로부터 만들어진 백신
|
US8298820B2
(en)
|
2010-01-26 |
2012-10-30 |
The Trustees Of The University Of Pennsylvania |
Influenza nucleic acid molecules and vaccines made therefrom
|
KR101784177B1
(ko)
|
2010-02-08 |
2017-10-11 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
Rantes를 암호화하는 핵산 분자, 그리고 이를 포함하는 조성물 및 이의 사용 방법
|
WO2012047679A2
(en)
|
2010-09-27 |
2012-04-12 |
The Trustees Of The University Of Pennsylvania |
Consensus antigen constructs and vaccines made there form, and methods of using same to treat malaria
|
AU2011325893B2
(en)
|
2010-11-12 |
2016-01-14 |
Inovio Pharmaceuticals, Inc |
Consensus prostate antigens nucleic acid molecule encoding the same and vaccine and uses comprising the same
|
JP6099573B2
(ja)
|
2011-01-31 |
2017-03-22 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア |
新規なヘルペス抗原をコードする核酸分子、それを含むワクチン及びその使用方法
|
US9238679B2
(en)
|
2011-02-11 |
2016-01-19 |
The Trustees Of The University Of Pennslyvania |
Nucleic acid molecule encoding hepatitis B virus core protein and surface antigen protein and vaccine comprising the same
|
PT2672992T
(pt)
|
2011-02-11 |
2020-07-27 |
Univ Pennsylvania |
Molécula de ácidos nucleicos codificando proteína nuclear do vírus da hepatite b e vacina compreendendo a mesma
|
CN103717249B
(zh)
|
2011-06-15 |
2017-03-22 |
克洛恩泰克制药股份公司 |
注射针和装置
|
CA2841852C
(en)
|
2011-07-11 |
2020-06-30 |
Inovio Pharmaceuticals, Inc. |
Cross-protective arenavirus vaccines and their method of use
|
US9750795B2
(en)
|
2011-12-12 |
2017-09-05 |
The Trustees Of The University Of Pennsylvania |
Proteins comprising MRSA PBP2a and fragments thereof, nucleic acids encoding the same, and compositions and their use to prevent and treat MRSA infections
|
EP3336096A1
(en)
|
2011-12-12 |
2018-06-20 |
The Trustees Of The University Of Pennsylvania |
Compositions, comprising improved il-12 genetic constructs and vaccines, immunotherapeutics and methods of using the same
|
CN104619719A
(zh)
|
2012-04-10 |
2015-05-13 |
宾夕法尼亚大学理事会 |
人呼吸道合胞病毒共有抗原、由其制备的核酸构建体和疫苗及其使用方法
|
CA2870293C
(en)
|
2012-04-12 |
2023-05-09 |
The Trustees Of The University Of Pennsylvania |
Filovirus consensus antigens, nucleic acid constructs and vaccines made therefrom, and methods of using same
|
DE102012013534B3
(de)
|
2012-07-05 |
2013-09-19 |
Tobias Sokolowski |
Vorrichtung für repetitive Nervenstimulation zum Abbau von Fettgewebe mittels induktiver Magnetfelder
|
WO2014064534A2
(en)
|
2012-10-05 |
2014-05-01 |
Chrontech Pharma Ab |
Injection needle, device, immunogenic compositions and method of use
|
KR20230038607A
(ko)
|
2012-12-13 |
2023-03-20 |
더 트러스티스 오브 더 유니버시티 오브 펜실베니아 |
Wt1 백신
|
WO2015089492A2
(en)
|
2013-12-13 |
2015-06-18 |
The Trustees Of The University Of Pennsylvania |
Dna antibody constructs and method of using same
|
KR20210088754A
(ko)
|
2013-03-15 |
2021-07-14 |
더 트러스티스 오브 더 유니버시티 오브 펜실베니아 |
구제역 바이러스 (fmdv) 공통 단백질, 그에 대한 코딩 서열 및 그로부터 제조된 백신
|
EA034110B1
(ru)
|
2013-03-15 |
2019-12-27 |
Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания |
Противораковые вакцины и способы лечения с их применением
|
KR20160037196A
(ko)
|
2013-07-31 |
2016-04-05 |
더 보드 오브 트러스티스 오브 더 유니버시티 오브 아칸소 |
종양 연관된 탄수화물 항원을 표적으로 하는 암을 치료하고 예방하기 위한 조성물과 방법
|
US11278619B2
(en)
|
2014-12-01 |
2022-03-22 |
The Trustees Of The University Of Pennsylvania |
DNA antibody constructs and method of using same
|
US11491342B2
(en)
|
2015-07-01 |
2022-11-08 |
Btl Medical Solutions A.S. |
Magnetic stimulation methods and devices for therapeutic treatments
|
US11266850B2
(en)
|
2015-07-01 |
2022-03-08 |
Btl Healthcare Technologies A.S. |
High power time varying magnetic field therapy
|
US20180001107A1
(en)
|
2016-07-01 |
2018-01-04 |
Btl Holdings Limited |
Aesthetic method of biological structure treatment by magnetic field
|
US10695575B1
(en)
|
2016-05-10 |
2020-06-30 |
Btl Medical Technologies S.R.O. |
Aesthetic method of biological structure treatment by magnetic field
|
WO2017055522A1
(en)
|
2015-09-29 |
2017-04-06 |
Academisch Medisch Centrum |
Stabilized env proteins of hiv
|
US11253717B2
(en)
|
2015-10-29 |
2022-02-22 |
Btl Healthcare Technologies A.S. |
Aesthetic method of biological structure treatment by magnetic field
|
CA3013718C
(en)
|
2016-02-05 |
2023-09-26 |
Jian Yan |
Cancer vaccines and methods of treatment using the same
|
AU2017241925B2
(en)
|
2016-03-28 |
2022-01-13 |
Ichor Medical Systems, Inc. |
Method and apparatus for delivery of therapeutic agents
|
JP7250520B2
(ja)
|
2016-04-13 |
2023-04-03 |
ヤンセン ファーマシューティカルズ,インコーポレーテッド |
組換えアルテリウイルスレプリコン系およびその使用
|
US11464993B2
(en)
|
2016-05-03 |
2022-10-11 |
Btl Healthcare Technologies A.S. |
Device including RF source of energy and vacuum system
|
US11247039B2
(en)
|
2016-05-03 |
2022-02-15 |
Btl Healthcare Technologies A.S. |
Device including RF source of energy and vacuum system
|
US11534619B2
(en)
|
2016-05-10 |
2022-12-27 |
Btl Medical Solutions A.S. |
Aesthetic method of biological structure treatment by magnetic field
|
US10583287B2
(en)
|
2016-05-23 |
2020-03-10 |
Btl Medical Technologies S.R.O. |
Systems and methods for tissue treatment
|
US10556122B1
(en)
|
2016-07-01 |
2020-02-11 |
Btl Medical Technologies S.R.O. |
Aesthetic method of biological structure treatment by magnetic field
|
WO2018075235A1
(en)
|
2016-10-17 |
2018-04-26 |
Synthetic Genomics, Inc. |
Recombinant virus replicon systems and uses thereof
|
US11845939B2
(en)
|
2016-12-05 |
2023-12-19 |
Janssen Pharmaceuticals, Inc. |
Compositions and methods for enhancing gene expression
|
WO2019042950A1
(en)
|
2017-08-26 |
2019-03-07 |
Academisch Medisch Centrum |
IMPROVED HIV ENVELOPE GLYCOPROTETIC IMMUNOGENS
|
EP3737397B1
(en)
|
2017-12-13 |
2022-11-30 |
Inovio Pharmaceuticals, Inc. |
Cancer vaccines targeting prame and uses thereof
|
EP3723812A4
(en)
|
2017-12-13 |
2022-02-16 |
Inovio Pharmaceuticals, Inc. |
MUC16-TARGETING CANCER VACCINES AND THEIR USES
|
AU2018383658B2
(en)
|
2017-12-13 |
2022-02-10 |
Inovio Pharmaceuticals, Inc. |
Cancer vaccines targeting mesothelin and uses thereof
|
EA202091517A1
(ru)
|
2017-12-19 |
2020-11-03 |
Янссен Сайенсиз Айрлэнд Анлимитед Компани |
Способы и устройство для доставки вакцин против вируса гепатита b (hbv)
|
MA51311A
(fr)
|
2017-12-19 |
2020-10-28 |
Janssen Sciences Ireland Unlimited Co |
Vaccins contre le virus de l'hépatite b (vhb) et utilisations associées
|
EA202091513A1
(ru)
|
2017-12-19 |
2020-09-09 |
Янссен Сайенсиз Айрлэнд Анлимитед Компани |
Вакцины против вируса гепатита b (hbv) и их применение
|
EA202091516A1
(ru)
|
2017-12-19 |
2020-11-03 |
Янссен Сайенсиз Айрлэнд Анлимитед Компани |
Способы и композиции для индукции иммунного ответа против вируса гепатита b (hbv)
|
KR20200100745A
(ko)
|
2017-12-19 |
2020-08-26 |
얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 |
B형 간염 바이러스(hbv)에 대한 면역 반응 유도를 위한 방법 및 조성물
|
US11083786B2
(en)
|
2018-01-19 |
2021-08-10 |
Janssen Pharmaceuticals, Inc. |
Induce and enhance immune responses using recombinant replicon systems
|
AU2020270557C1
(en)
|
2019-04-11 |
2022-01-20 |
Btl Medical Solutions A.S. |
Methods and devices for aesthetic treatment of biological structures by radiofrequency and magnetic energy
|
KR20220041080A
(ko)
|
2019-06-18 |
2022-03-31 |
얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 |
B형 간염 바이러스(hbv) 백신 및 항-pd-1 또는 항-pc-l1 항체의 조합
|
CA3140708A1
(en)
|
2019-06-18 |
2020-12-24 |
Helen Horton |
Combination of hepatitis b virus (hbv) vaccines and pyridopyrimidine derivatives
|
US20220233684A1
(en)
|
2019-06-18 |
2022-07-28 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis b virus (hbv) vaccines and pd-l1 inhibitors
|
WO2020255010A1
(en)
|
2019-06-18 |
2020-12-24 |
Janssen Sciences Ireland Unlimited Company |
Combination of recombinant interleukin 12 construct and hepatitis b virus (hbv) vaccines
|
WO2020255039A1
(en)
|
2019-06-18 |
2020-12-24 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis b virus (hbv) vaccines and quinazoline derivatives
|
AU2020297008A1
(en)
|
2019-06-18 |
2022-02-17 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis B virus (HBV) vaccines and HBV-targeting RNAi
|
WO2020255019A1
(en)
|
2019-06-18 |
2020-12-24 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis b virus (hbv) vaccines and a quinazoline derivative
|
WO2020254876A1
(en)
|
2019-06-18 |
2020-12-24 |
Janssen Sciences Ireland Unlimited Company |
Virus-like particle delivery of hepatitis b virus (hbv) vaccines
|
WO2020255013A1
(en)
|
2019-06-18 |
2020-12-24 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis b virus (hbv) vaccines and capsid assembly modulators being amide derivatives
|
CA3141323A1
(en)
|
2019-06-18 |
2020-12-24 |
Helen Horton |
Recombinant interleukin 12 construct and uses thereof
|
CA3140690A1
(en)
|
2019-06-18 |
2020-12-24 |
Helen Horton |
Combination of hepatitis b virus (hbv) vaccines and dihydropyrimidine derivatives as capsid assembly modulators
|
CA3140702A1
(en)
|
2019-06-18 |
2020-12-24 |
Helen Horton |
Combination of hepatitis b virus (hbv) vaccines and dihydropyrimidine derivatives as capsid assembly modulators
|
WO2020255042A1
(en)
|
2019-06-18 |
2020-12-24 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis b virus (hbv) vaccines and a pyrimidine derivative
|
EP3986562A1
(en)
|
2019-06-18 |
2022-04-27 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis b virus (hbv) vaccines and hbv-targeting rnai
|
EP3986460A2
(en)
|
2019-06-18 |
2022-04-27 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis b virus (hbv) vaccines and anti-pd-1 antibody
|
US20220305114A1
(en)
|
2019-06-18 |
2022-09-29 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis b virus (hbv) vaccines and small molecule pdl1 or pd1 inhibitor
|
WO2020255035A1
(en)
|
2019-06-18 |
2020-12-24 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis b virus (hbv) vaccines and pyrimidine derivatives
|
WO2020255022A1
(en)
|
2019-06-18 |
2020-12-24 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis b virus (hbv) vaccines and aminopyridine derivatives as hpk1 inhibitors
|
US20220324916A1
(en)
|
2019-06-18 |
2022-10-13 |
Janssen Sciences Ireland Unlimited Company |
Hepatitis B Virus (HBV) Vaccines and Uses Thereof
|
WO2020255016A1
(en)
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|
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|
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|
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|
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|
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