IL125380A0 - Anticoagulant agents useful in treatment of thrombosis - Google Patents

Anticoagulant agents useful in treatment of thrombosis

Info

Publication number
IL125380A0
IL125380A0 IL12538097A IL12538097A IL125380A0 IL 125380 A0 IL125380 A0 IL 125380A0 IL 12538097 A IL12538097 A IL 12538097A IL 12538097 A IL12538097 A IL 12538097A IL 125380 A0 IL125380 A0 IL 125380A0
Authority
IL
Israel
Prior art keywords
thrombosis
treatment
agents useful
anticoagulant agents
anticoagulant
Prior art date
Application number
IL12538097A
Other languages
English (en)
Original Assignee
Smithkline Beecham Corp
Univ Vermont
State Agricultural College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp, Univ Vermont, State Agricultural College filed Critical Smithkline Beecham Corp
Publication of IL125380A0 publication Critical patent/IL125380A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL12538097A 1996-01-17 1997-01-17 Anticoagulant agents useful in treatment of thrombosis IL125380A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1010896P 1996-01-17 1996-01-17
US2911996P 1996-10-24 1996-10-24
PCT/US1997/000759 WO1997026010A1 (en) 1996-01-17 1997-01-17 Anticoagulant agents useful in treatment of thrombosis

Publications (1)

Publication Number Publication Date
IL125380A0 true IL125380A0 (en) 1999-03-12

Family

ID=26680794

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12538097A IL125380A0 (en) 1996-01-17 1997-01-17 Anticoagulant agents useful in treatment of thrombosis

Country Status (26)

Country Link
US (5) US6005091A (cs)
EP (2) EP1832297A1 (cs)
JP (2) JP2000503210A (cs)
KR (1) KR100553629B1 (cs)
CN (1) CN1213312A (cs)
AR (1) AR005658A1 (cs)
AT (1) ATE330630T1 (cs)
AU (1) AU706397B2 (cs)
BR (1) BR9707049A (cs)
CZ (1) CZ299452B6 (cs)
DE (1) DE69736197T2 (cs)
DK (1) DK1007089T3 (cs)
ES (1) ES2267131T3 (cs)
HK (1) HK1029513A1 (cs)
HU (1) HU225903B1 (cs)
ID (1) ID17156A (cs)
IL (1) IL125380A0 (cs)
MA (1) MA24512A1 (cs)
MX (1) MX9805810A (cs)
NO (1) NO983284L (cs)
NZ (2) NZ331014A (cs)
PL (1) PL187274B1 (cs)
PT (1) PT1007089E (cs)
SI (1) SI1007089T1 (cs)
TR (1) TR199801390T2 (cs)
WO (1) WO1997026010A1 (cs)

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US6818749B1 (en) 1998-10-31 2004-11-16 The United States Of America As Represented By The Department Of Health And Human Services Variants of humanized anti carcinoma monoclonal antibody cc49
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US7067313B1 (en) 1999-07-14 2006-06-27 D. Collen Research Foundation Ligands for use in therapeutic compositions for the treatment of hemostasis disorders
US7829085B2 (en) 1999-07-14 2010-11-09 Life Sciences Research Partners Vzw Methods of treating hemostasis disorders using antibodies binding the C1 domain of factor VIII
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ATE468136T1 (de) 2001-01-11 2010-06-15 D Collen Res Foundation Vzw Verfahren und pharmazeutische zusammensetzung zur vorbeugung und/oder behandlung des syndroms der systemischen entzündlichen reaktion
JP2005508838A (ja) * 2001-03-23 2005-04-07 アフトン コーポレーション 膵癌の組合せ治療
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CA2580965C (en) 2004-09-22 2014-04-08 Receptor Biologix, Inc. Monoclonal antibodies to progastrin
ES2592271T3 (es) 2005-03-31 2016-11-29 Chugai Seiyaku Kabushiki Kaisha Métodos de producción de polipéptidos mediante la regulación de la asociación de los polipéptidos
EP4218801A3 (en) 2006-03-31 2023-08-23 Chugai Seiyaku Kabushiki Kaisha Antibody modification method for purifying bispecific antibody
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CN101842388B (zh) 2007-09-13 2013-09-04 德勒尼克斯治疗股份公司 针对β淀粉样肽的人源化抗体
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US8187591B2 (en) * 2007-10-11 2012-05-29 The Regents Of The University Of California Methods of treating coagulopathy
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US10442868B2 (en) 2013-03-14 2019-10-15 Rhode Island Hospital, A Lifespan-Partner Treating hepatitis B virus infections by administering receptor associated protein (RAP)
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EP3194437B1 (en) 2014-08-07 2021-01-20 Novartis AG Angiopoietin-like 4 (angptl4) antibodies and methods of use
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TWI701435B (zh) 2014-09-26 2020-08-11 日商中外製藥股份有限公司 測定fviii的反應性之方法
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WO2016159213A1 (ja) 2015-04-01 2016-10-06 中外製薬株式会社 ポリペプチド異種多量体の製造方法
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MA24512A1 (fr) * 1996-01-17 1998-12-31 Univ Vermont And State Agrienl Procede pour la preparation d'agents anticoagulants utiles dans le traitement de la thrombose
US20070190059A1 (en) * 1996-01-17 2007-08-16 Smithkline Beecham Corporation Antithrombotic agents

Also Published As

Publication number Publication date
CZ222598A3 (cs) 2000-01-12
EP1007089A1 (en) 2000-06-14
MX9805810A (es) 1998-11-30
EP1832297A1 (en) 2007-09-12
US20020146411A1 (en) 2002-10-10
AU706397B2 (en) 1999-06-17
PL187274B1 (pl) 2004-06-30
NO983284D0 (no) 1998-07-16
JP2007325602A (ja) 2007-12-20
BR9707049A (pt) 2000-10-24
EP1007089A4 (en) 2003-04-16
NO983284L (no) 1998-09-16
NZ501215A (en) 2001-04-27
EP1007089B1 (en) 2006-06-21
KR19990077329A (ko) 1999-10-25
MA24512A1 (fr) 1998-12-31
SI1007089T1 (sl) 2006-12-31
ES2267131T3 (es) 2007-03-01
PL327929A1 (en) 1999-01-04
TR199801390T2 (xx) 1998-12-21
DE69736197T2 (de) 2007-06-21
DE69736197D1 (de) 2006-08-03
JP2000503210A (ja) 2000-03-21
US20070003553A1 (en) 2007-01-04
KR100553629B1 (ko) 2006-10-04
HUP9900396A3 (en) 2001-10-29
US20070224198A1 (en) 2007-09-27
US6391299B1 (en) 2002-05-21
NZ331014A (en) 2000-01-28
HK1029513A1 (en) 2001-04-06
CN1213312A (zh) 1999-04-07
WO1997026010A1 (en) 1997-07-24
HUP9900396A2 (hu) 1999-05-28
DK1007089T3 (da) 2006-10-09
AU1830897A (en) 1997-08-11
AR005658A1 (es) 1999-07-14
ATE330630T1 (de) 2006-07-15
ID17156A (id) 1997-12-04
US6005091A (en) 1999-12-21
HU225903B1 (en) 2007-12-28
PT1007089E (pt) 2006-11-30
CZ299452B6 (cs) 2008-07-30

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