MX9805810A - Agentes anticoagulantes, utiles en el tratamiento de trombosis. - Google Patents

Agentes anticoagulantes, utiles en el tratamiento de trombosis.

Info

Publication number
MX9805810A
MX9805810A MX9805810A MX9805810A MX9805810A MX 9805810 A MX9805810 A MX 9805810A MX 9805810 A MX9805810 A MX 9805810A MX 9805810 A MX9805810 A MX 9805810A MX 9805810 A MX9805810 A MX 9805810A
Authority
MX
Mexico
Prior art keywords
thrombosis
treatment
agents useful
anticoagulant agents
anticoagulant
Prior art date
Application number
MX9805810A
Other languages
English (en)
Inventor
Michael Neal Blackburn
William Robert Church
Giora Zeev Feuerstein
Mitchell Stuart Gross
Andrew John Nichols
Eduardo Agustin Padlan
Arunbhai Haribhai Patel
Daniel Robert Sylvester
Original Assignee
Smithkline Beecham Corp
Univ Vermont And State
Agricultural College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp, Univ Vermont And State, Agricultural College filed Critical Smithkline Beecham Corp
Publication of MX9805810A publication Critical patent/MX9805810A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Están descritos anticuerpos monoclonales dirigidos contra los factores de coagulacion, y su uso en la inhibicion de la trombosis.
MX9805810A 1996-01-17 1998-07-17 Agentes anticoagulantes, utiles en el tratamiento de trombosis. MX9805810A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1010896P 1996-01-17 1996-01-17
US2911996P 1996-10-24 1996-10-24

Publications (1)

Publication Number Publication Date
MX9805810A true MX9805810A (es) 1998-11-30

Family

ID=26680794

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9805810A MX9805810A (es) 1996-01-17 1998-07-17 Agentes anticoagulantes, utiles en el tratamiento de trombosis.

Country Status (26)

Country Link
US (5) US6005091A (es)
EP (2) EP1832297A1 (es)
JP (2) JP2000503210A (es)
KR (1) KR100553629B1 (es)
CN (1) CN1213312A (es)
AR (1) AR005658A1 (es)
AT (1) ATE330630T1 (es)
AU (1) AU706397B2 (es)
BR (1) BR9707049A (es)
CZ (1) CZ299452B6 (es)
DE (1) DE69736197T2 (es)
DK (1) DK1007089T3 (es)
ES (1) ES2267131T3 (es)
HK (1) HK1029513A1 (es)
HU (1) HU225903B1 (es)
ID (1) ID17156A (es)
IL (1) IL125380A0 (es)
MA (1) MA24512A1 (es)
MX (1) MX9805810A (es)
NO (1) NO983284L (es)
NZ (2) NZ501215A (es)
PL (1) PL187274B1 (es)
PT (1) PT1007089E (es)
SI (1) SI1007089T1 (es)
TR (1) TR199801390T2 (es)
WO (1) WO1997026010A1 (es)

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WO2004003155A2 (en) 2002-06-28 2004-01-08 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Humanized anti-tag-72 cc49 for diagnosis and therapy of human tumors
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US7589181B2 (en) 2003-08-29 2009-09-15 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Minimally immunogenic variants of SDR-grafted humanized antibody CC49 and their use
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WO2005035753A1 (ja) * 2003-10-10 2005-04-21 Chugai Seiyaku Kabushiki Kaisha 機能蛋白質を代替する二重特異性抗体
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ES2592271T3 (es) 2005-03-31 2016-11-29 Chugai Seiyaku Kabushiki Kaisha Métodos de producción de polipéptidos mediante la regulación de la asociación de los polipéptidos
JP5624276B2 (ja) 2006-03-31 2014-11-12 中外製薬株式会社 抗体の血中動態を制御する方法
CN105177091A (zh) 2006-03-31 2015-12-23 中外制药株式会社 用于纯化双特异性抗体的抗体修饰方法
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EP2185592B1 (en) * 2007-09-13 2013-01-23 University Of Zurich Prorektorat Forschung Monoclonal amyloid beta (abeta)-specific antibody and uses thereof
EP4368721A2 (en) 2007-09-26 2024-05-15 Chugai Seiyaku Kabushiki Kaisha Method of modifying isoelectric point of antibody via amino acid substitution in cdr
US8187591B2 (en) * 2007-10-11 2012-05-29 The Regents Of The University Of California Methods of treating coagulopathy
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JP2022515770A (ja) 2018-12-21 2022-02-22 カイマブ・リミテッド 共通の軽鎖を有するFIXa×FX二重特異性抗体

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Also Published As

Publication number Publication date
KR19990077329A (ko) 1999-10-25
NO983284L (no) 1998-09-16
DK1007089T3 (da) 2006-10-09
JP2007325602A (ja) 2007-12-20
PT1007089E (pt) 2006-11-30
EP1832297A1 (en) 2007-09-12
ATE330630T1 (de) 2006-07-15
DE69736197D1 (de) 2006-08-03
AU706397B2 (en) 1999-06-17
PL187274B1 (pl) 2004-06-30
HK1029513A1 (en) 2001-04-06
CZ299452B6 (cs) 2008-07-30
SI1007089T1 (sl) 2006-12-31
NZ501215A (en) 2001-04-27
ID17156A (id) 1997-12-04
US20070003553A1 (en) 2007-01-04
IL125380A0 (en) 1999-03-12
EP1007089A4 (en) 2003-04-16
EP1007089A1 (en) 2000-06-14
MA24512A1 (fr) 1998-12-31
DE69736197T2 (de) 2007-06-21
JP2000503210A (ja) 2000-03-21
WO1997026010A1 (en) 1997-07-24
TR199801390T2 (xx) 1998-12-21
CN1213312A (zh) 1999-04-07
EP1007089B1 (en) 2006-06-21
HUP9900396A2 (hu) 1999-05-28
ES2267131T3 (es) 2007-03-01
AU1830897A (en) 1997-08-11
US6005091A (en) 1999-12-21
NZ331014A (en) 2000-01-28
CZ222598A3 (cs) 2000-01-12
KR100553629B1 (ko) 2006-10-04
BR9707049A (pt) 2000-10-24
US20020146411A1 (en) 2002-10-10
NO983284D0 (no) 1998-07-16
US20070224198A1 (en) 2007-09-27
HU225903B1 (en) 2007-12-28
PL327929A1 (en) 1999-01-04
AR005658A1 (es) 1999-07-14
US6391299B1 (en) 2002-05-21
HUP9900396A3 (en) 2001-10-29

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