IL122119A - Inverted cells that produce virus particles - Google Patents
Inverted cells that produce virus particlesInfo
- Publication number
- IL122119A IL122119A IL12211996A IL12211996A IL122119A IL 122119 A IL122119 A IL 122119A IL 12211996 A IL12211996 A IL 12211996A IL 12211996 A IL12211996 A IL 12211996A IL 122119 A IL122119 A IL 122119A
- Authority
- IL
- Israel
- Prior art keywords
- cells
- capsule
- sulphate
- capsule according
- group
- Prior art date
Links
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- 230000006798 recombination Effects 0.000 description 1
- 238000005215 recombination Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 230000004043 responsiveness Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- FHHPUSMSKHSNKW-SMOYURAASA-M sodium deoxycholate Chemical compound [Na+].C([C@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC([O-])=O)C)[C@@]2(C)[C@@H](O)C1 FHHPUSMSKHSNKW-SMOYURAASA-M 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- JJICLMJFIKGAAU-UHFFFAOYSA-M sodium;2-amino-9-(1,3-dihydroxypropan-2-yloxymethyl)purin-6-olate Chemical compound [Na+].NC1=NC([O-])=C2N=CN(COC(CO)CO)C2=N1 JJICLMJFIKGAAU-UHFFFAOYSA-M 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
- 210000004881 tumor cell Anatomy 0.000 description 1
- 238000005199 ultracentrifugation Methods 0.000 description 1
- 241001529453 unidentified herpesvirus Species 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13041—Use of virus, viral particle or viral elements as a vector
- C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK74095 | 1995-06-27 | ||
| PCT/EP1996/002748 WO1997001357A1 (fr) | 1995-06-27 | 1996-06-24 | Cellules encapsulees produisant des particules virales |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL122119A0 IL122119A0 (en) | 1998-04-05 |
| IL122119A true IL122119A (en) | 2004-06-01 |
Family
ID=8097001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12211996A IL122119A (en) | 1995-06-27 | 1996-06-24 | Inverted cells that produce virus particles |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6776985B1 (fr) |
| EP (1) | EP0835137B1 (fr) |
| JP (2) | JP4119952B2 (fr) |
| KR (1) | KR100484883B1 (fr) |
| CN (1) | CN1187095C (fr) |
| AT (1) | ATE309000T1 (fr) |
| AU (1) | AU708273B2 (fr) |
| CA (1) | CA2222559A1 (fr) |
| CZ (1) | CZ286979B6 (fr) |
| DE (1) | DE69633180D1 (fr) |
| DK (1) | DK0835137T3 (fr) |
| ES (1) | ES2253754T3 (fr) |
| HK (1) | HK1010139A1 (fr) |
| IL (1) | IL122119A (fr) |
| NO (1) | NO321427B1 (fr) |
| NZ (1) | NZ312671A (fr) |
| PL (1) | PL185338B1 (fr) |
| PT (1) | PT835137E (fr) |
| RU (1) | RU2187301C2 (fr) |
| SI (1) | SI0835137T1 (fr) |
| UA (1) | UA65525C2 (fr) |
| WO (1) | WO1997001357A1 (fr) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT817858E (pt) | 1995-03-09 | 2003-09-30 | Gsf Forschungszentrum Umwelt U | Preparacoes fotoprotectoras que compreendem derivados de triazina |
| PT835137E (pt) | 1995-06-27 | 2004-12-31 | Gsf Forschungszentrum Umwelt U | Celulas encapsuladas produtoras de particulas virais |
| DE69730595D1 (de) | 1996-03-27 | 2004-10-14 | Bavarian Nordic As Kvistgaard | Verkapselte zellen expremierend cytochrome p450 für die aktivierung einer medikamentenvorstufe |
| US6540995B1 (en) | 1996-03-27 | 2003-04-01 | Bavarian Nordic Research Institute Gmbh | Encapsulated cells producing cytochrome P450 |
| CN1266362A (zh) | 1998-05-05 | 2000-09-13 | 皇家菲利浦电子有限公司 | 包括具有刷毛区和齿间刷毛区的毛刷件的牙刷 |
| WO2005095450A2 (fr) | 2004-03-30 | 2005-10-13 | Nsgene A/S | Utilisation therapeutique d'un facteur de croissance, nsg33 |
| EP1879622A2 (fr) * | 2005-05-03 | 2008-01-23 | Veterinärmedizinische Universität Wien | Capsules permeables |
| WO2009085850A2 (fr) * | 2007-12-20 | 2009-07-09 | Ethicon, Incorporated | Tissu rénal encapsulé |
| KR101250925B1 (ko) * | 2011-10-28 | 2013-04-04 | 한화케미칼 주식회사 | 캡슐 세포용 구조체 |
| GB201408233D0 (en) | 2014-05-09 | 2014-06-25 | Austrianova Singapore Pte Ltd | Use of polyanionic composition |
| ES2939617T3 (es) * | 2015-11-24 | 2023-04-25 | Glaxosmithkline Ip Dev Ltd | Líneas celulares estables para producción retroviral |
| FR3044017B1 (fr) * | 2015-11-24 | 2019-05-03 | Glaxosmithkline Intellectual Property Development Limited | Procede de transfection transitoire pour la production retrovirale |
| EP3464571B1 (fr) * | 2016-05-25 | 2021-04-14 | Lonza Houston Inc. | Procédés d'isolement de virus adéno-associé à l'aide d'un sel de polydiallyldialkylammonium |
| RU2688383C2 (ru) * | 2017-07-10 | 2019-05-21 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Саратовский национальный исследовательский государственный университет имени Н.Г. Чернышевского" | Способ синтеза белка в культуре бактериальных клеток |
| CN110615667B (zh) * | 2018-06-19 | 2022-02-15 | 华北理工大学 | 基于铁尾矿和碱渣的核壳结构陶粒及其制备方法 |
| EP4340821A2 (fr) * | 2021-05-21 | 2024-03-27 | Bionaut Labs Ltd. | Système et procédé de traitement thérapeutique localisé |
| CN115820683B (zh) * | 2022-09-28 | 2024-04-05 | 西南大学 | 家蚕Cyp9a20基因及其应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4391909A (en) * | 1979-03-28 | 1983-07-05 | Damon Corporation | Microcapsules containing viable tissue cells |
| DD160393A3 (de) * | 1980-11-14 | 1983-07-27 | Horst Dautzenberg | Mikrokapseln und verfahren zu ihrer herstellung |
| US4686098A (en) * | 1984-05-14 | 1987-08-11 | Merck & Co., Inc. | Encapsulated mouse cells transformed with avian retrovirus-bovine growth hormone DNA, and a method of administering BGH in vivo |
| US4680174A (en) * | 1984-05-24 | 1987-07-14 | Damon Biotech, Inc. | Induction of immune response by immunization with encapsulated antigen-producing cells |
| EP0199362A3 (fr) * | 1985-04-26 | 1987-10-07 | Massachusetts Institute Of Technology | Système et dispositif pour la libération retardée et par à-coups de substances biologiquement actives |
| CA1310924C (fr) * | 1986-04-24 | 1992-12-01 | Francis P. Mccormick | Systeme d'administration d'un medicament a l'aide de particules infectieuses |
| EP0371119B1 (fr) | 1988-05-17 | 1996-09-04 | Sloan-Kettering Institute For Cancer Research | Vecteur retroviral |
| US5328470A (en) * | 1989-03-31 | 1994-07-12 | The Regents Of The University Of Michigan | Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor |
| DE4021050A1 (de) * | 1990-06-29 | 1992-01-02 | Akad Wissenschaften Ddr | Verfahren zur herstellung von mikrokapseln |
| CA2051288C (fr) * | 1990-09-14 | 2002-02-05 | Robert L. Martuza | Destruction ciblee de cellules neoplasiques par un virus |
| JPH06500927A (ja) * | 1990-12-13 | 1994-01-27 | アメリカ合衆国 | 高力価の組換えウイルスベクターおよび遺伝子療法に用いられる形質導入標的細胞の持続的及び連続的生産 |
| WO1994029437A1 (fr) | 1993-06-07 | 1994-12-22 | University Of Medicine & Dentistry Of New Jersey | Vecteurs retroviraux exempts de region u3, exempts de recombinaison, a auto-inactivation, hautement efficaces |
| US5688773A (en) | 1994-08-17 | 1997-11-18 | The General Hospital Corporation | Method of selectively destroying neoplastic cells |
| CA2198210C (fr) | 1994-09-02 | 2006-07-11 | Walter Henry Gunzburg | Vecteurs retroviraux utiles comme vehicules de transfert genique pour therapie genique |
| PT835137E (pt) | 1995-06-27 | 2004-12-31 | Gsf Forschungszentrum Umwelt U | Celulas encapsuladas produtoras de particulas virais |
| AU6987696A (en) | 1995-09-06 | 1997-03-27 | Bavarian Nordic Research Institute A/S | The use of the wap of mmtv regulatory sequences for targeted expression of linked heterologous genes in human mammary cells, including human mammary carcinoma cells |
| DE69730595D1 (de) | 1996-03-27 | 2004-10-14 | Bavarian Nordic As Kvistgaard | Verkapselte zellen expremierend cytochrome p450 für die aktivierung einer medikamentenvorstufe |
-
1996
- 1996-06-24 PT PT96923905T patent/PT835137E/pt unknown
- 1996-06-24 NZ NZ312671A patent/NZ312671A/xx not_active IP Right Cessation
- 1996-06-24 CA CA002222559A patent/CA2222559A1/fr not_active Abandoned
- 1996-06-24 IL IL12211996A patent/IL122119A/en not_active IP Right Cessation
- 1996-06-24 DK DK96923905T patent/DK0835137T3/da active
- 1996-06-24 CN CNB961950501A patent/CN1187095C/zh not_active Expired - Fee Related
- 1996-06-24 ES ES96923905T patent/ES2253754T3/es not_active Expired - Lifetime
- 1996-06-24 AT AT96923905T patent/ATE309000T1/de not_active IP Right Cessation
- 1996-06-24 SI SI9630729T patent/SI0835137T1/sl unknown
- 1996-06-24 EP EP96923905A patent/EP0835137B1/fr not_active Expired - Lifetime
- 1996-06-24 UA UA97126354A patent/UA65525C2/uk unknown
- 1996-06-24 WO PCT/EP1996/002748 patent/WO1997001357A1/fr active IP Right Grant
- 1996-06-24 AU AU64154/96A patent/AU708273B2/en not_active Expired
- 1996-06-24 CZ CZ19974195A patent/CZ286979B6/cs not_active IP Right Cessation
- 1996-06-24 KR KR1019970709807A patent/KR100484883B1/ko not_active IP Right Cessation
- 1996-06-24 RU RU98101362/13A patent/RU2187301C2/ru not_active IP Right Cessation
- 1996-06-24 DE DE69633180T patent/DE69633180D1/de not_active Expired - Lifetime
- 1996-06-24 PL PL96324289A patent/PL185338B1/pl not_active IP Right Cessation
- 1996-06-24 JP JP50416597A patent/JP4119952B2/ja not_active Expired - Lifetime
-
1997
- 1997-12-10 NO NO19975813A patent/NO321427B1/no not_active IP Right Cessation
- 1997-12-23 US US08/996,460 patent/US6776985B1/en not_active Expired - Lifetime
-
1998
- 1998-09-26 HK HK98110992A patent/HK1010139A1/xx not_active IP Right Cessation
-
2007
- 2007-11-21 JP JP2007301109A patent/JP4848348B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| PL324289A1 (en) | 1998-05-11 |
| CA2222559A1 (fr) | 1997-01-16 |
| NO975813L (no) | 1998-02-23 |
| PT835137E (pt) | 2004-12-31 |
| CN1187095C (zh) | 2005-02-02 |
| ES2253754T3 (es) | 2006-06-01 |
| AU708273B2 (en) | 1999-07-29 |
| CZ419597A3 (cs) | 1998-03-18 |
| US6776985B1 (en) | 2004-08-17 |
| IL122119A0 (en) | 1998-04-05 |
| CN1189104A (zh) | 1998-07-29 |
| EP0835137A1 (fr) | 1998-04-15 |
| KR100484883B1 (ko) | 2005-09-02 |
| PL185338B1 (pl) | 2003-04-30 |
| SI0835137T1 (sl) | 2006-04-30 |
| KR19990028491A (ko) | 1999-04-15 |
| HK1010139A1 (en) | 1999-06-17 |
| WO1997001357A1 (fr) | 1997-01-16 |
| EP0835137B1 (fr) | 2005-11-09 |
| JPH11508768A (ja) | 1999-08-03 |
| DK0835137T3 (da) | 2006-03-06 |
| ATE309000T1 (de) | 2005-11-15 |
| JP2008101011A (ja) | 2008-05-01 |
| NO975813D0 (no) | 1997-12-10 |
| JP4119952B2 (ja) | 2008-07-16 |
| NO321427B1 (no) | 2006-05-08 |
| NZ312671A (en) | 1999-10-28 |
| AU6415496A (en) | 1997-01-30 |
| DE69633180D1 (de) | 2004-09-23 |
| UA65525C2 (en) | 2004-04-15 |
| JP4848348B2 (ja) | 2011-12-28 |
| RU2187301C2 (ru) | 2002-08-20 |
| CZ286979B6 (en) | 2000-08-16 |
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| Date | Code | Title | Description |
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| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| EXP | Patent expired |