IL113854A0 - Process for detecting evanescently excited luminescence and a device for its use - Google Patents

Process for detecting evanescently excited luminescence and a device for its use

Info

Publication number
IL113854A0
IL113854A0 IL11385495A IL11385495A IL113854A0 IL 113854 A0 IL113854 A0 IL 113854A0 IL 11385495 A IL11385495 A IL 11385495A IL 11385495 A IL11385495 A IL 11385495A IL 113854 A0 IL113854 A0 IL 113854A0
Authority
IL
Israel
Prior art keywords
pct
luminescence
layer
sec
substances
Prior art date
Application number
IL11385495A
Other languages
English (en)
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL113854A0 publication Critical patent/IL113854A0/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G01N21/774—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure
    • G01N21/7743—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure the reagent-coated grating coupling light in or out of the waveguide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Testing, Inspecting, Measuring Of Stereoscopic Televisions And Televisions (AREA)
  • Manufacture, Treatment Of Glass Fibers (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
IL11385495A 1994-05-27 1995-05-25 Process for detecting evanescently excited luminescence and a device for its use IL113854A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH164394 1994-05-27

Publications (1)

Publication Number Publication Date
IL113854A0 true IL113854A0 (en) 1995-08-31

Family

ID=4215258

Family Applications (2)

Application Number Title Priority Date Filing Date
IL11385495A IL113854A0 (en) 1994-05-27 1995-05-25 Process for detecting evanescently excited luminescence and a device for its use
IL11384995A IL113849A0 (en) 1994-05-27 1995-05-25 Process for detecting excited luminescence

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL11384995A IL113849A0 (en) 1994-05-27 1995-05-25 Process for detecting excited luminescence

Country Status (21)

Country Link
US (2) US5959292A (fr)
EP (2) EP0760944B1 (fr)
JP (3) JP3645907B2 (fr)
KR (1) KR970703527A (fr)
CN (2) CN1149336A (fr)
AT (2) ATE216491T1 (fr)
AU (2) AU2317995A (fr)
CA (2) CA2190362A1 (fr)
CZ (2) CZ347296A3 (fr)
DE (2) DE69505370T2 (fr)
DK (1) DK0760944T3 (fr)
ES (1) ES2174948T3 (fr)
FI (2) FI964664A (fr)
HU (2) HUT76407A (fr)
IL (2) IL113854A0 (fr)
MX (1) MXPA96005828A (fr)
PL (2) PL317402A1 (fr)
SK (2) SK151296A3 (fr)
TW (2) TW295624B (fr)
WO (2) WO1995033197A1 (fr)
ZA (2) ZA954325B (fr)

Families Citing this family (150)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5959292A (en) * 1994-05-27 1999-09-28 Novartis Corporation Process for detecting evanescently excited luminescence
US5814565A (en) 1995-02-23 1998-09-29 University Of Utah Research Foundation Integrated optic waveguide immunosensor
US6078705A (en) 1995-05-12 2000-06-20 Novartis Ag Sensor platform and method for the parallel detection of a plurality of analytes using evanescently excited luminescence
GB9602542D0 (en) * 1996-02-08 1996-04-10 Fisons Plc Analytical device
DE59712897D1 (de) 1996-03-30 2008-01-03 Novartis Ag Integriert optischer lumineszenzsensor
JPH102860A (ja) * 1996-06-17 1998-01-06 Olympus Optical Co Ltd 微小物質検鏡装置
EP0922214A1 (fr) * 1996-08-29 1999-06-16 Novartis AG Capteur optique chimique/biochimique
US6198869B1 (en) 1996-11-18 2001-03-06 Novartis Ag Measuring device and its use
EP0843173A1 (fr) 1996-11-18 1998-05-20 Novartis AG Cellule à circulation de fluide et appareil pour produire une radiation par excitation evanescente
WO1999013320A1 (fr) * 1997-09-10 1999-03-18 Artificial Sensing Instruments Asi Ag Capteur optique et procede optique de caracterisation d'une substance chimique et/ou biochimique
JP4662623B2 (ja) * 1998-02-05 2011-03-30 ノバルティス アーゲー ルミネッセンスを測定する方法及び装置
EP2112501A1 (fr) 1998-02-05 2009-10-28 Novartis Ag Procédé et dispositif destinés à la mesure de la luminescence
US6758337B2 (en) * 1999-03-02 2004-07-06 Meadwestvaco Packaging Systems, Llc Beverage carton with strap type carrying handle
EP0957354A3 (fr) * 1998-03-20 2000-03-22 IA Inc. Procédé et dispositif de mesure de la fixation de molécules biologiques
DE19815109A1 (de) * 1998-04-03 1999-10-07 Bodenseewerk Perkin Elmer Co Vorrichtung zum Nachweis eines Fluoreszenzfarbstoffs
FR2778986B1 (fr) 1998-05-22 2000-07-21 Suisse Electronique Microtech Capteur optique utilisant une reaction immunologique et un marqueur fluorescent
WO2000005582A2 (fr) * 1998-07-21 2000-02-03 Burstein Laboratories, Inc. Dispositifs de dosage utilisant des disques optiques et methodes correspondantes
US6320991B1 (en) * 1998-10-16 2001-11-20 Imation Corp. Optical sensor having dielectric film stack
US6245518B1 (en) 1998-12-11 2001-06-12 Hyseq, Inc. Polynucleotide arrays and methods of making and using the same
EP1031828B1 (fr) * 1999-02-25 2006-09-13 C.S.E.M. Centre Suisse D'electronique Et De Microtechnique Sa Capteur en optique intégrée et méthode pour déterminer en optique intégrée une substance
US6192168B1 (en) * 1999-04-09 2001-02-20 The United States Of America As Represented By The Secretary Of The Navy Reflectively coated optical waveguide and fluidics cell integration
US6137117A (en) * 1999-06-21 2000-10-24 The United States Of America As Represented By The Secretary Of The Navy Integrating multi-waveguide sensor
WO2000079235A1 (fr) * 1999-06-23 2000-12-28 Patrick Toomey Recherche d'eau et de sa provenance dans des structures par spectroscopie de rayonnement electromagnetique
US6771376B2 (en) 1999-07-05 2004-08-03 Novartis Ag Sensor platform, apparatus incorporating the platform, and process using the platform
ATE340996T1 (de) 1999-07-05 2006-10-15 Novartis Pharma Gmbh Verfahren zur anwendung einer sensoreinheit
US7708945B1 (en) 1999-08-13 2010-05-04 Bayer Technology Services Gmbh Device and method for determining multiple analytes
US6667179B1 (en) * 1999-10-28 2003-12-23 The Board Of Trustees Of The University Of Illinois Semiconductor luminescence quenchers for detecting proximal molecular binding events
US7167615B1 (en) 1999-11-05 2007-01-23 Board Of Regents, The University Of Texas System Resonant waveguide-grating filters and sensors and methods for making and using same
FR2801977B1 (fr) * 1999-12-02 2002-05-17 Commissariat Energie Atomique Amplification d'un signal de fluorescence emis par un echantillon surfacique
JP4599019B2 (ja) 1999-12-17 2010-12-15 バイエル・テクノロジー・サービシーズ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング フローセル配列及び多重分析対象物測定のためのその利用
US6510263B1 (en) * 2000-01-27 2003-01-21 Unaxis Balzers Aktiengesellschaft Waveguide plate and process for its production and microtitre plate
US20030108291A1 (en) * 2000-04-14 2003-06-12 Duveneck Gert Ludwig Grid-waveguide structure for reinforcing an excitation field and use thereof
JP2003532123A (ja) 2000-04-28 2003-10-28 エッジライト バイオサイエンシズ インコーポレイテッド マイクロアレーエバネッセント波蛍光検出装置
AU2001274068A1 (en) 2000-06-02 2001-12-11 Zeptosens Ag Kit and method for determining a plurality of analytes
WO2002001194A1 (fr) * 2000-06-25 2002-01-03 Affymetrix, Inc. Substrats optiquement actifs
EP2275802A1 (fr) 2000-08-09 2011-01-19 Artificial Sensing Instruments ASI AG Structure de grille conductrice d'ondes et agencement de mesure optique
EP1327135B1 (fr) * 2000-09-04 2010-02-24 Bayer Technology Services GmbH Systeme et procedes pour determiner plusieurs analytes
DE50113602D1 (de) * 2000-09-05 2008-03-27 Bayer Technology Services Gmbh Verfahren zur abscheidung von mono- und mehrfachscd deren salzen sowie deren verwendung
ATE508363T1 (de) * 2000-12-06 2011-05-15 Ecole Polytech Verfahren zur herstellung eines bioanalytischen reagenzes, nachweisverfahren beruhend auf der verwendung des bioanalytischen reagenz, sowie dessen verwendung
FR2818382B1 (fr) * 2000-12-20 2003-02-21 Commissariat Energie Atomique Support pour determiner un analyte tel qu'une cible adn ou arn, comportant un filtre spectral selectif
DE10108483A1 (de) * 2001-02-22 2002-09-05 Bayer Ag Phosphorhaltige Polymere für optischen Signalwandler
EP1237128B1 (fr) 2001-03-01 2012-08-01 Sicpa Holding Sa Détecteur de caractéristiques de luminescence amélioré
US20040052489A1 (en) * 2001-04-02 2004-03-18 Duveneck Gert Ludwig Optical structure for multi-photon excitation and the use thereof
DE10133844B4 (de) * 2001-07-18 2006-08-17 Micronas Gmbh Verfahren und Vorrichtung zur Detektion von Analyten
US6782013B2 (en) * 2001-07-25 2004-08-24 Jds Uniphase Corporation Waveguide wavelength locker
US6671304B2 (en) * 2001-08-28 2003-12-30 The United States Of America As Represented By The Secretary Of The Navy Amplitude-modulated laser for high-bandwidth communications systems
WO2003020488A1 (fr) * 2001-08-30 2003-03-13 Zeptosens Ag Procede de fabrication de corps moules, en particulier de structures optiques, et leur utilisation
WO2003042697A1 (fr) * 2001-11-14 2003-05-22 Genospectra, Inc. Systeme d'analyse biochimique a applications de chimique combinatoire
DE10158149A1 (de) * 2001-11-28 2003-06-18 Bayer Ag Silangruppen enthaltende Polymere
US7179654B2 (en) * 2002-03-18 2007-02-20 Agilent Technologies, Inc. Biochemical assay with programmable array detection
JP2003308714A (ja) * 2002-04-17 2003-10-31 Fuji Photo Film Co Ltd 導光フィルム
US20030232427A1 (en) * 2002-06-18 2003-12-18 Montagu Jean I. Optically active substrates for examination of biological materials
US7154598B2 (en) * 2002-07-12 2006-12-26 Decision Biomarkers, Inc. Excitation and imaging of fluorescent arrays
US7384742B2 (en) * 2002-08-16 2008-06-10 Decision Biomarkers, Inc. Substrates for isolating reacting and microscopically analyzing materials
US7190522B2 (en) 2002-09-12 2007-03-13 Cyvera Corporation Chemical synthesis using diffraction grating-based encoded optical elements
JP2005536769A (ja) 2002-08-20 2005-12-02 シヴェラ コーポレイション 回折格子をベースとする光学同定要素
US7164533B2 (en) 2003-01-22 2007-01-16 Cyvera Corporation Hybrid random bead/chip based microarray
US7872804B2 (en) 2002-08-20 2011-01-18 Illumina, Inc. Encoded particle having a grating with variations in the refractive index
US7508608B2 (en) 2004-11-17 2009-03-24 Illumina, Inc. Lithographically fabricated holographic optical identification element
US7900836B2 (en) 2002-08-20 2011-03-08 Illumina, Inc. Optical reader system for substrates having an optically readable code
CA2497297A1 (fr) * 2002-08-30 2004-03-11 Bayer Healthcare Llc Dosages d'acide nucleique en rapport avec une phase solide, combinant une haute affinite avec une haute specificite
ATE520027T1 (de) 2002-09-03 2011-08-15 Bayer Technology Services Gmbh Analytische plattform und nachweisverfahren mit gegebenenfalls nach fraktionierung in einer probe nachzuweisenden analyten als immobilisierten spezifischen bindungspartnern
AU2003258683A1 (en) * 2002-09-03 2004-03-29 Zeptosens Ag Analytical platform and detection method with analytes which are to be detected in a sample in the form of immobilized specific binding partners
US7092160B2 (en) 2002-09-12 2006-08-15 Illumina, Inc. Method of manufacturing of diffraction grating-based optical identification element
US20100255603A9 (en) 2002-09-12 2010-10-07 Putnam Martin A Method and apparatus for aligning microbeads in order to interrogate the same
EP1540592A1 (fr) 2002-09-12 2005-06-15 Cyvera Corporation Procede et appareil d'etiquetage utilisant des elements d'identification optique codes a reseau de diffraction
DE10245435B4 (de) 2002-09-27 2006-03-16 Micronas Gmbh Vorrichtung zur Detektion mindestens eines in einer zu untersuchenden Probe enthaltenen Liganden
US7027163B2 (en) * 2003-01-24 2006-04-11 General Dynamics Advanced Information Systems, Inc. Grating sensor
US7445938B2 (en) * 2003-01-24 2008-11-04 General Dynamics Advanced Information Systems, Inc. System and method for detecting presence of analytes using gratings
US7545494B2 (en) * 2003-07-23 2009-06-09 Bayer Technology Services Gmbh Analytical system and method for analyzing nonlinear optical signals
DE10353694A1 (de) * 2003-11-18 2005-06-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Mikroskopievorrichtung
GB0327755D0 (en) * 2003-12-01 2003-12-31 Elliott Stephen R Optical-sensor chip
JP4480130B2 (ja) * 2003-12-16 2010-06-16 キヤノン株式会社 光学分析装置
US7433123B2 (en) 2004-02-19 2008-10-07 Illumina, Inc. Optical identification element having non-waveguide photosensitive substrate with diffraction grating therein
CN1954213A (zh) * 2004-03-03 2007-04-25 拜尔技术服务有限责任公司 用于产生细胞群体的蛋白表达谱的分析平台和方法
US7080839B2 (en) * 2004-06-29 2006-07-25 Michael Shackleford Blackjack variations
RU2396548C2 (ru) 2004-07-02 2010-08-10 БАЙЕР ХЕЛТКЭР ЭлЭлСи Световодный тестовый датчик для определения исследуемого вещества в пробе флюида (варианты) и способы его изготовления (варианты)
ES2292273B1 (es) * 2004-07-13 2009-02-16 Fabrica Nacional De Moneda Y Timbre - Real Casa De La Moneda Pigmentos luminiscentes utilizados en documentos de seguridad y procedimiento de deteccion de los mismos.
WO2006020363A2 (fr) 2004-07-21 2006-02-23 Illumina, Inc. Procede et dispositif de suivi de produits medicamenteux au moyen d'elements d'identification optique codes
US7678567B2 (en) * 2004-07-26 2010-03-16 Kabushiki Kaisha Toshiba Optical biosensor
EP1621869B1 (fr) * 2004-07-26 2015-08-19 Kabushiki Kaisha Toshiba Biocapteur optique
CN100449313C (zh) * 2004-07-30 2009-01-07 株式会社东芝 光学式生物传感器
CN101696937B (zh) * 2004-07-30 2012-07-04 株式会社东芝 光学式生物传感器
DE602005019791D1 (de) 2004-11-16 2010-04-15 Illumina Inc Verfahren und vorrichtung zum lesen von kodierten mikrokugeln
US7403284B2 (en) * 2004-12-16 2008-07-22 Andevices, Inc. Integrated optics based high-resolution spectrophotometer
JP2005099054A (ja) * 2004-12-27 2005-04-14 Olympus Corp 微小物質の蛍光測定装置
US7327908B1 (en) * 2005-03-07 2008-02-05 Lightsmyth Technologies Inc. Integrated optical sensor incorporating sets of diffractive elements
GB0507835D0 (en) * 2005-04-18 2005-05-25 Solexa Ltd Method and device for nucleic acid sequencing using a planar wave guide
AU2006239534B2 (en) 2005-04-26 2012-05-31 Bayer Intellectual Property Gmbh Novel equipment and method for coating substrates for analyte detection by way of an affinity assay method
US7136005B1 (en) * 2005-05-05 2006-11-14 Analog Devices, Inc. Accurate low noise analog to digital converter system
CN101238360A (zh) * 2005-08-08 2008-08-06 康宁股份有限公司 用于增大ccd-检测器的读出速率的方法
EP1938086A1 (fr) 2005-10-12 2008-07-02 Koninklijke Philips Electronics N.V. Capteur optique de guide d'ondes constitue integralement de polymere
EP2269724A1 (fr) 2005-10-29 2011-01-05 Bayer Technology Services GmbH Procédé de détermination d'un ou plusieurs analytes dans des échantillons d'origine biologique assemblés de manière complexe et leur utilisation
DE102005062785A1 (de) * 2005-12-28 2007-07-05 Robert Bosch Gmbh Regensensor, insbesondere für ein Kraftfahrzeug, und Verfahren zur Herstellung des Regensensors
US20070196863A1 (en) * 2006-02-17 2007-08-23 Hanson Technologies, Inc. Prion protein detection
US9976192B2 (en) 2006-03-10 2018-05-22 Ldip, Llc Waveguide-based detection system with scanning light source
US7951583B2 (en) 2006-03-10 2011-05-31 Plc Diagnostics, Inc. Optical scanning system
US8675199B2 (en) 2006-03-10 2014-03-18 Plc Diagnostics, Inc. Waveguide-based detection system with scanning light source
US9528939B2 (en) 2006-03-10 2016-12-27 Indx Lifecare, Inc. Waveguide-based optical scanning systems
US8288157B2 (en) 2007-09-12 2012-10-16 Plc Diagnostics, Inc. Waveguide-based optical scanning systems
US9423397B2 (en) 2006-03-10 2016-08-23 Indx Lifecare, Inc. Waveguide-based detection system with scanning light source
SE529711C2 (sv) * 2006-03-22 2007-11-06 Aamic Ab Fluorescensläsare
US7830575B2 (en) 2006-04-10 2010-11-09 Illumina, Inc. Optical scanner with improved scan time
WO2007127564A2 (fr) 2006-04-26 2007-11-08 Siemens Medical Solutions Diagnostics Gmbh Dosage d'acides nucléiques sur phase solide combinant une capture et une détection à haute affinité par hybridation spécifique
US20080101744A1 (en) * 2006-10-31 2008-05-01 Honeywell International Inc. Optical Waveguide Sensor Devices and Methods For Making and Using Them
US20100093107A1 (en) * 2006-12-14 2010-04-15 University Of Massachusetts Polymer-protein substrates for immunosorbent fluorescence assays
US9475051B2 (en) 2007-02-27 2016-10-25 Sony Corporation Nucleic acid amplifier
JP4458133B2 (ja) * 2007-02-27 2010-04-28 ソニー株式会社 核酸増幅装置
US20090325211A1 (en) * 2007-10-06 2009-12-31 Ye Fang System and method for dual-detection of a cellular response
AT506177B1 (de) * 2008-03-26 2009-07-15 Univ Graz Tech Optischer sensor
EP2110694B1 (fr) 2008-04-18 2013-08-14 Sony DADC Austria AG Procédé de fabrication d'un guide d'onde optique, guide d'onde optique, et agencement de capteur
DE102008019928A1 (de) 2008-04-21 2009-12-31 Siemens Healthcare Diagnostics Gmbh Polyelektrolyt-Monoschichten mit kovalenten Bindungsstellen für optische Signalwandler
GB2461026B (en) 2008-06-16 2011-03-09 Plc Diagnostics Inc System and method for nucleic acids sequencing by phased synthesis
US9212995B2 (en) 2009-03-02 2015-12-15 Mbio Diagnostics, Inc. System and method for detecting multiple molecules in one assay
US9658222B2 (en) 2009-03-02 2017-05-23 Mbio Diagnostics, Inc. Planar waveguide based cartridges and associated methods for detecting target analyte
US8331751B2 (en) * 2009-03-02 2012-12-11 mBio Diagnositcs, Inc. Planar optical waveguide with core of low-index-of-refraction interrogation medium
US8300993B2 (en) * 2009-03-02 2012-10-30 Mbio Diagnostics, Inc. Waveguide with integrated lens
DE102009016712A1 (de) 2009-04-09 2010-10-14 Bayer Technology Services Gmbh Einweg-Mikrofluidik-Testkassette zur Bioassay von Analyten
WO2010115530A1 (fr) 2009-04-09 2010-10-14 Bayer Cropscience Aktiengesellschaft Dispositif et procédé pour la détection et pour l'analyse quantitative d'analytes, notamment de mycotoxines
US8154716B2 (en) * 2009-09-04 2012-04-10 Octrolix Bv Waveguide-based sensor
DE102010019095B4 (de) * 2010-04-30 2016-12-08 Deutsches Zentrum für Luft- und Raumfahrt e.V. Verfahren und Vorrichtung zur Fluoreszenzlebensdauermessung
EP2616797B1 (fr) 2010-09-15 2017-01-11 MBIO Diagnostics Inc. Systeme et procede de detection de multiples molecules dans un test
WO2013009308A1 (fr) * 2011-07-13 2013-01-17 Empire Technology Development Llc Procédé et système de surveillance d'analyte à l'aide de plasmons de surface ayant une surface apte à être régénérée
US9989525B2 (en) 2013-03-15 2018-06-05 Axela Inc. Diffraction based biosensor containing two diffractive gratings
US20150077756A1 (en) * 2013-06-13 2015-03-19 Lumense, Inc. System and method for continuous real-time monitoring of water at contaminated sites
US9863880B2 (en) 2013-11-17 2018-01-09 Quantum-Si Incorporated Optical system and assay chip for probing, detecting and analyzing molecules
US10018566B2 (en) 2014-02-28 2018-07-10 Ldip, Llc Partially encapsulated waveguide based sensing chips, systems and methods of use
US9702813B2 (en) * 2014-07-23 2017-07-11 Infineon Technologies Ag Sensing systems and methods using a coupling structure
AU2015300779B2 (en) 2014-08-08 2021-03-04 Quantum-Si Incorporated Integrated device with external light source for probing, detecting, and analyzing molecules
MX2017001806A (es) 2014-08-08 2018-01-30 Quantum Si Inc Dispositivo integrado para el depósito temporal de fotones recibidos.
KR20220165282A (ko) 2014-08-08 2022-12-14 퀀텀-에스아이 인코포레이티드 분자들을 프로빙, 검출 및 분석하기 위한 광학계 및 검정 칩
WO2016138427A1 (fr) 2015-02-27 2016-09-01 Indx Lifecare, Inc. Système de détection à guide d'ondes à source de lumière à balayage
US10605730B2 (en) 2015-05-20 2020-03-31 Quantum-Si Incorporated Optical sources for fluorescent lifetime analysis
US11466316B2 (en) 2015-05-20 2022-10-11 Quantum-Si Incorporated Pulsed laser and bioanalytic system
US10246742B2 (en) 2015-05-20 2019-04-02 Quantum-Si Incorporated Pulsed laser and bioanalytic system
US10174363B2 (en) 2015-05-20 2019-01-08 Quantum-Si Incorporated Methods for nucleic acid sequencing
TWI734748B (zh) 2016-02-17 2021-08-01 美商太斯萊特健康股份有限公司 用於生命期成像及偵測應用之感測器及裝置
AU2017375481A1 (en) 2016-12-16 2019-06-20 Quantum-Si Incorporated Compact mode-locked laser module
CA3047108A1 (fr) 2016-12-16 2018-06-21 Quantum-Si Incorporated Ensemble compact de direction et de mise en forme de faisceau
CA3047826A1 (fr) 2016-12-22 2018-06-28 Quantum-Si Incorporated Photodetecteur integre a pixel de compartimentage direct
TWI653449B (zh) 2018-01-31 2019-03-11 國立交通大學 光子晶體與磁珠結合的螢光免疫檢測裝置和方法
DE102018202591A1 (de) * 2018-02-21 2019-08-22 Robert Bosch Gmbh Optisches System sowie ein Verfahren zur Herstellung eines optischen Systems
RU2737056C1 (ru) 2018-03-29 2020-11-24 Иллюмина, Инк. Освещение для флуоресцентной визуализации с помощью линзы объектива
CN112424587A (zh) 2018-06-15 2021-02-26 宽腾矽公司 用于具有脉冲光源的先进分析仪器的数据采集控制
WO2019246328A1 (fr) 2018-06-22 2019-12-26 Quantum-Si Incorporated Photodétecteur intégré à intervalle de stockage de charge à temps de détection varié
CN111742212B (zh) 2019-01-08 2024-02-20 京东方科技集团股份有限公司 流体检测面板和流体检测装置
CN109632660B (zh) * 2019-01-17 2022-04-05 京东方科技集团股份有限公司 流体检测面板
CN114303082A (zh) 2019-06-14 2022-04-08 宽腾矽公司 具有提升的波束校准灵敏度的分割光栅耦合器
DE102021133357A1 (de) 2021-12-15 2023-06-15 Endress+Hauser Conducta Gmbh+Co. Kg Sensorelement, Sensorsystem und Verfahren zum Herstellen des Sensorelements
TWI796944B (zh) * 2022-01-28 2023-03-21 國立中山大學 螢光增強基板及螢光檢測裝置

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4582809A (en) * 1982-06-14 1986-04-15 Myron J. Block Apparatus including optical fiber for fluorescence immunoassay
AU5815886A (en) * 1985-05-29 1986-12-24 Kurt Tiefenthaler Optical sensor for selectively determining the presence of substances and the variation of the refraction index in the measured substances
BR8807884A (pt) * 1988-02-14 1990-11-13 Walter Lukosz Processo de interferencia otico integrado
GB8807486D0 (en) * 1988-03-29 1988-05-05 Ares Serono Res & Dev Ltd Waveguide sensor
GB8827853D0 (en) * 1988-11-29 1988-12-29 Ares Serono Res & Dev Ltd Sensor for optical assay
US5082629A (en) * 1989-12-29 1992-01-21 The Board Of The University Of Washington Thin-film spectroscopic sensor
EP0517777B1 (fr) * 1990-03-02 1996-05-22 FISONS plc Cellule echantillon pour utilisation dans les analyses chimiques ou biologiques
EP0478923B1 (fr) * 1990-08-31 1997-11-05 Texas Instruments Incorporated Procédé pour fabriquer des transistors bipolaires à hétéro-jonction auto-alignés
DE4228853C2 (de) * 1991-09-18 1993-10-21 Schott Glaswerke Optischer Wellenleiter mit einem planaren oder nur geringfügig gewölbten Substrat und Verfahren zu dessen Herstellung sowie Verwendung eines solchen
US5418371A (en) * 1993-02-01 1995-05-23 Aslund; Nils R. D. Apparatus for quantitative imaging of multiple fluorophores using dual detectors
US5294799A (en) * 1993-02-01 1994-03-15 Aslund Nils R D Apparatus for quantitative imaging of multiple fluorophores
US5959292A (en) * 1994-05-27 1999-09-28 Novartis Corporation Process for detecting evanescently excited luminescence

Also Published As

Publication number Publication date
ATE216491T1 (de) 2002-05-15
TW295624B (fr) 1997-01-11
EP0759159A1 (fr) 1997-02-26
HUT76407A (en) 1997-08-28
FI964684A0 (fi) 1996-11-25
ZA954325B (en) 1995-11-27
DE69526438D1 (de) 2002-05-23
HU9603261D0 (en) 1997-01-28
EP0760944A1 (fr) 1997-03-12
SK151396A3 (en) 1997-07-09
CN1149336A (zh) 1997-05-07
CZ347296A3 (en) 1997-03-12
JPH10501616A (ja) 1998-02-10
EP0760944B1 (fr) 2002-04-17
FI964664A (fi) 1997-01-24
ZA954327B (en) 1995-11-27
EP0759159B1 (fr) 1998-10-14
TW278135B (fr) 1996-06-11
JP2005326426A (ja) 2005-11-24
CZ347196A3 (en) 1997-06-11
DE69505370D1 (de) 1998-11-19
CA2190643A1 (fr) 1995-12-07
MXPA96005828A (es) 2005-07-15
FI964664A0 (fi) 1996-11-22
FI964684A (fi) 1997-01-27
AU689604B2 (en) 1998-04-02
DE69526438T2 (de) 2002-10-31
KR970703527A (ko) 1997-07-03
AU2317995A (en) 1995-12-21
WO1995033197A1 (fr) 1995-12-07
ES2174948T3 (es) 2002-11-16
PL317402A1 (en) 1997-04-14
IL113849A0 (en) 1995-08-31
AU2734695A (en) 1995-12-21
CN1149335A (zh) 1997-05-07
HUT76406A (en) 1997-08-28
HU9603260D0 (en) 1997-01-28
US5822472A (en) 1998-10-13
US5959292A (en) 1999-09-28
ATE172300T1 (de) 1998-10-15
PL317379A1 (en) 1997-04-01
SK151296A3 (en) 1997-07-09
CA2190362A1 (fr) 1995-12-07
JPH10501617A (ja) 1998-02-10
WO1995033198A1 (fr) 1995-12-07
DE69505370T2 (de) 1999-04-01
JP3645907B2 (ja) 2005-05-11
DK0760944T3 (da) 2002-08-05

Similar Documents

Publication Publication Date Title
IL113854A0 (en) Process for detecting evanescently excited luminescence and a device for its use
AU5763296A (en) Sensor platform and method for the parallel detection of a plurality of analytes using evanescently excited luminescence
WO2001092870A3 (fr) Kit et procede pour la detection d'une pluralite d'analytes
ATE412171T1 (de) Faseroptische assay-vorrichtung auf der basis der phasenverschiebungs-interferometrie
AU4520093A (en) Improvement in optical assays
SE9200917D0 (sv) Assay method
ATE220208T1 (de) Überwachung des refraktionsindex von optischen sensoren zur bestimmung von änderungen in der oberflächenstruktur
DE59915078D1 (fr)
WO2002059253A3 (fr) Systeme de detection de fluorescence comprenant une structure de bande interdite photonique
Wolfbeis Capillary waveguide sensors
SE9403078D0 (sv) Milk assay
JP3968425B2 (ja) 光導波路への光導入方法及びそれを用いた光導波路分光測定装置
DE59806188D1 (de) Vorrichtung und verfahren zur durchführung von fluoreszenzimmunotests
Kohls et al. Development and comparison of pH microoptodes for use in marine systems
SE9600914D0 (sv) Gassensor
KR970703526A (ko) 소실되어 여기된 발광의 검출방법(Process for detecting evanescently excited luminescence)