SE9200917D0 - Assay method - Google Patents

Assay method

Info

Publication number
SE9200917D0
SE9200917D0 SE9200917A SE9200917A SE9200917D0 SE 9200917 D0 SE9200917 D0 SE 9200917D0 SE 9200917 A SE9200917 A SE 9200917A SE 9200917 A SE9200917 A SE 9200917A SE 9200917 D0 SE9200917 D0 SE 9200917D0
Authority
SE
Sweden
Prior art keywords
pct
refractive index
analyte
sec
wavelength
Prior art date
Application number
SE9200917A
Other languages
English (en)
Inventor
A Hanning
Original Assignee
Pharmacia Biosensor Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9102397A external-priority patent/SE468962B/sv
Application filed by Pharmacia Biosensor Ab filed Critical Pharmacia Biosensor Ab
Priority to SE9200917A priority Critical patent/SE9200917D0/sv
Publication of SE9200917D0 publication Critical patent/SE9200917D0/sv
Priority to PCT/SE1992/000558 priority patent/WO1993004357A1/en
Priority to US08/193,128 priority patent/US5573956A/en
Priority to JP5504255A priority patent/JPH06510367A/ja
Priority to EP92918059A priority patent/EP0599956B1/en
Priority to AU24648/92A priority patent/AU2464892A/en
Priority to DE69217375T priority patent/DE69217375T2/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769—Measurement method of reaction-produced change in sensor
    • G01N2021/7776—Index
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/41—Refractivity; Phase-affecting properties, e.g. optical path length
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G01N21/553—Attenuated total reflection and using surface plasmons
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/808—Optical sensing apparatus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
SE9200917A 1991-08-20 1992-03-25 Assay method SE9200917D0 (sv)

Priority Applications (7)

Application Number Priority Date Filing Date Title
SE9200917A SE9200917D0 (sv) 1991-08-20 1992-03-25 Assay method
PCT/SE1992/000558 WO1993004357A1 (en) 1991-08-20 1992-08-19 Assay method
US08/193,128 US5573956A (en) 1991-08-20 1992-08-19 Assay method based upon refractive index changes at a solid optical surface
JP5504255A JPH06510367A (ja) 1991-08-20 1992-08-19 アッセイ法
EP92918059A EP0599956B1 (en) 1991-08-20 1992-08-19 Assay method
AU24648/92A AU2464892A (en) 1991-08-20 1992-08-19 Assay method
DE69217375T DE69217375T2 (de) 1991-08-20 1992-08-19 Bestimmungsverfahren

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9102397A SE468962B (sv) 1991-08-20 1991-08-20 Saett att analysera med avseende paa en analyt i ett vaetskeprov
SE9200917A SE9200917D0 (sv) 1991-08-20 1992-03-25 Assay method

Publications (1)

Publication Number Publication Date
SE9200917D0 true SE9200917D0 (sv) 1992-03-25

Family

ID=26661146

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9200917A SE9200917D0 (sv) 1991-08-20 1992-03-25 Assay method

Country Status (7)

Country Link
US (1) US5573956A (sv)
EP (1) EP0599956B1 (sv)
JP (1) JPH06510367A (sv)
AU (1) AU2464892A (sv)
DE (1) DE69217375T2 (sv)
SE (1) SE9200917D0 (sv)
WO (1) WO1993004357A1 (sv)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9201984D0 (sv) * 1992-06-29 1992-06-29 Pharmacia Biosensor Ab Improvement in optical assays
SE500817C2 (sv) * 1993-01-27 1994-09-12 Anders Hanning Sätt att bestämma koncentrationen av en analyt i ett vätskekromatografiskt eller kapillärelektroforetiskt flöde genom att mäta vätskans brytningsindex
SE501663C2 (sv) * 1993-08-24 1995-04-10 Anders Hanning Refraktometrisk metod för indirekt detektion av ett ämne
US6521185B1 (en) * 1995-10-23 2003-02-18 American Research Corporation Of Virginia Fluorescent probes based on the affinity of a polymer matrix for an analyte of interest
GB9602542D0 (en) * 1996-02-08 1996-04-10 Fisons Plc Analytical device
EP0901630B1 (en) * 1996-05-23 2003-08-20 Inverness Medical Switzerland GmbH Improvements in or relating to specific binding assays
SE9602788L (sv) * 1996-07-16 1998-01-17 Anders Hanning Förbättrad refraktometrisk metod
US6165798A (en) * 1996-10-10 2000-12-26 University Of British Columbia Optical quantification of analytes in membranes
US6686208B2 (en) * 1997-03-18 2004-02-03 Institut Fur Chemo- Und Biosensorik Munster E.V. Device and method for carrying out fluoresence immunotests
US5859937A (en) * 1997-04-04 1999-01-12 Neomecs Incorporated Minimally invasive sensor
EP1443320A3 (de) 1997-09-10 2005-02-02 Artificial Sensing Instruments ASI AG Sensorchip zur Charakterisierung einer chemischen und/oder biochemischen Substanz
US6346376B1 (en) * 1998-06-03 2002-02-12 Centre Suisse D'electronique Et De Mictotechnique Sa Optical sensor unit and procedure for the ultrasensitive detection of chemical or biochemical analytes
US6432364B1 (en) * 1998-07-06 2002-08-13 Suzuki Motor Corporation SPR sensor cell and immunoassay apparatus using the same
US7167615B1 (en) 1999-11-05 2007-01-23 Board Of Regents, The University Of Texas System Resonant waveguide-grating filters and sensors and methods for making and using same
US6833920B2 (en) 2000-07-11 2004-12-21 Maven Technologies Llc Apparatus and method for imaging
US7518724B2 (en) * 2000-07-11 2009-04-14 Maven Technologies Image acquisition, processing, and display
US20020093654A1 (en) * 2000-07-11 2002-07-18 Lieberman Robert A. Apparatus and method for imaging
US7126688B2 (en) * 2000-07-11 2006-10-24 Maven Technologies, Llc Microarray scanning
US6594011B1 (en) 2000-07-11 2003-07-15 Maven Technologies, Llc Imaging apparatus and method
US7193711B2 (en) * 2000-07-11 2007-03-20 Maven Technologies, Llc Imaging method and apparatus
US7023547B2 (en) * 2000-07-11 2006-04-04 Maven Technologies, Llc Apparatus including a biochip for imaging of biological samples and method
DE10047007C2 (de) * 2000-09-22 2002-08-29 Fraunhofer Ges Forschung Verfahren zum Nachweis eines Analyten in einem Probenträger und entsprechende Vorrichtung
EP1322710B2 (en) 2000-09-29 2015-02-18 Life Technologies Corporation Modified carbocyanine dyes and their conjugates
US7951583B2 (en) 2006-03-10 2011-05-31 Plc Diagnostics, Inc. Optical scanning system
US8288157B2 (en) 2007-09-12 2012-10-16 Plc Diagnostics, Inc. Waveguide-based optical scanning systems
US9423397B2 (en) 2006-03-10 2016-08-23 Indx Lifecare, Inc. Waveguide-based detection system with scanning light source
US9528939B2 (en) 2006-03-10 2016-12-27 Indx Lifecare, Inc. Waveguide-based optical scanning systems
US9976192B2 (en) 2006-03-10 2018-05-22 Ldip, Llc Waveguide-based detection system with scanning light source
US7867783B2 (en) 2007-02-22 2011-01-11 Maven Technologies, Llc Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
WO2008110026A1 (de) 2007-03-13 2008-09-18 Creoptix Gmbh Integriert-optischer sensor
US7863037B1 (en) 2007-04-04 2011-01-04 Maven Technologies, Llc Ligand binding assays on microarrays in closed multiwell plates
US20090041633A1 (en) * 2007-05-14 2009-02-12 Dultz Shane C Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
US7799558B1 (en) 2007-05-22 2010-09-21 Dultz Shane C Ligand binding assays on microarrays in closed multiwell plates
US8039270B2 (en) * 2008-05-22 2011-10-18 Maven Technologies, Llc Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
US7981664B1 (en) 2008-05-22 2011-07-19 Maven Technologies, Llc Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
GB2461026B (en) 2008-06-16 2011-03-09 Plc Diagnostics Inc System and method for nucleic acids sequencing by phased synthesis
JP5757535B2 (ja) 2009-04-29 2015-07-29 ピーエルシー ダイアグノスティクス， インコーポレイテッド 走査光源による導波管に基づく検出システム
US8355133B2 (en) * 2009-12-30 2013-01-15 Maven Technologies, Llc Biological testing with sawtooth-shaped prisms
CN103097875B (zh) 2010-05-27 2015-11-25 艾皮森泰克公司 改进的传感器测量方法
WO2013075979A1 (en) 2011-11-22 2013-05-30 Episentec Ab Method for sensor calibration
WO2015028571A1 (en) 2013-08-29 2015-03-05 Episentec Ab Improved method of sensor measurement
JP6540710B2 (ja) 2013-11-19 2019-07-10 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ 速い解離速度の相互作用カイネティクスの決定方法
EP3083052B1 (en) 2013-12-19 2019-09-25 GE Healthcare Bio-Sciences AB Laminated microfluidic device with membrane valves
US10018566B2 (en) 2014-02-28 2018-07-10 Ldip, Llc Partially encapsulated waveguide based sensing chips, systems and methods of use
JP6662525B2 (ja) 2014-06-24 2020-03-11 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ 光学センサ表面における物質移動特性の正規化
EP3213071B1 (en) 2014-10-30 2019-07-10 GE Healthcare Bio-Sciences AB Method to determine solvent correction curves
US11181479B2 (en) 2015-02-27 2021-11-23 Ldip, Llc Waveguide-based detection system with scanning light source
GB202107754D0 (en) 2021-05-31 2021-07-14 Univ Newcastle Screening for the effects of complement protein changes

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986000135A1 (en) * 1984-06-13 1986-01-03 Unilever Plc Photometric instruments, their use in methods of optical analyses, and ancillary devices therefor
GB2197065A (en) * 1986-11-03 1988-05-11 Stc Plc Optical sensor device
US4954435A (en) * 1987-01-12 1990-09-04 Becton, Dickinson And Company Indirect colorimetric detection of an analyte in a sample using ratio of light signals
IL85137A (en) * 1987-01-21 1992-02-16 Ares Serono Res & Dev Ltd Method of assaying for a ligand using surface plasmon resonance effect
NL8700851A (nl) * 1987-04-10 1988-11-01 Tno Werkwijze en inrichting voor het detecteren van zeer lage concentraties van een in een meetmedium aanwezige chemische component onder toepassing van oppervlakte-plasmonresonantie en elektrochemisch gestimuleerde adsorptie.
CA1321488C (en) * 1987-08-22 1993-08-24 Martin Francis Finlan Biological sensors
DE68907519T2 (de) * 1988-05-10 1993-10-21 Amersham Int Plc Biosensoren.
EP0341928A1 (en) * 1988-05-10 1989-11-15 AMERSHAM INTERNATIONAL plc Improvements relating to surface plasmon resonance sensors
SE462408B (sv) * 1988-11-10 1990-06-18 Pharmacia Ab Optiskt biosensorsystem utnyttjande ytplasmonresonans foer detektering av en specific biomolekyl, saett att kalibrera sensoranordningen samt saett att korrigera foer baslinjedrift i systemet
GB8906776D0 (en) * 1989-03-23 1989-05-10 Amersham Int Plc Assay method using surface plasmon resonance spectrometry

Also Published As

Publication number Publication date
EP0599956B1 (en) 1997-02-05
JPH06510367A (ja) 1994-11-17
EP0599956A1 (en) 1994-06-08
US5573956A (en) 1996-11-12
DE69217375T2 (de) 1998-06-10
AU2464892A (en) 1993-03-16
DE69217375D1 (de) 1997-03-20
WO1993004357A1 (en) 1993-03-04

Similar Documents

Publication Publication Date Title
SE9200917D0 (sv) Assay method
SE9201984D0 (sv) Improvement in optical assays
AU2734695A (en) Process for detecting evanescently excited luminescence
DE69938663D1 (de) Optisch basierte sensor-vorrichtungen
ATE67853T1 (de) Biologische nachweisvorrichtung.
DK0649535T3 (da) Fremgangsmåde til at forbedre målepræcisionen i optisk biosensor assays med detektering af rumligt dæmpede bølger
DK0524224T3 (da) Metode til at forbedre analysefølsomhed
SE9503028D0 (sv) Method of analysing chemical and physical interactions at a sensor surface
DK0605598T3 (da) Fremgangsmåden ved fotometrisk in vitro bestemmelse af indholdet af en analyt i en prøve
ES2087183T3 (es) Sistema de analisis y procedimiento para la determinacion de un analito en una muestra fluida.
SE9403078D0 (sv) Milk assay
DK0418486T3 (da) Reagens anvendeligt til påvisning og kvantitativ bestemmelse af leukocyter i biologiske væsker samt fremgangsmåde til anvendelse deraf
WO1998041843A3 (de) Vorrichtung und verfahren zur durchführung von fluoreszenzimmunotests
SE9403908L (sv) Anordning för att detektera fluorescens
EP0950892A3 (en) Device for measuring optical density
DE59307666D1 (de) Licht leitendes Analyseelement zur Bestimmung eines Analyts
SE9300231D0 (sv) Foerbaettrad metod foer brytningsindexdetektion i vaetska
SE9102397D0 (sv) Assay method
SE9602788L (sv) Förbättrad refraktometrisk metod
FI915510A (fi) Analytiska element som innehaoller icke-reagerande blockerande faergaemne.