IL112851A - Process for preparing ¬L¾-or ¬D¾-homoalanin-4-yl-(methyl) phosphonic acid and salts thereof by racemate resolution - Google Patents

Process for preparing ¬L¾-or ¬D¾-homoalanin-4-yl-(methyl) phosphonic acid and salts thereof by racemate resolution

Info

Publication number
IL112851A
IL112851A IL11285195A IL11285195A IL112851A IL 112851 A IL112851 A IL 112851A IL 11285195 A IL11285195 A IL 11285195A IL 11285195 A IL11285195 A IL 11285195A IL 112851 A IL112851 A IL 112851A
Authority
IL
Israel
Prior art keywords
homoalanin
methyl
racemate resolution
salts
preparing
Prior art date
Application number
IL11285195A
Other languages
English (en)
Other versions
IL112851A0 (en
Original Assignee
Hoechst Schering Agrevo Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Schering Agrevo Gmbh filed Critical Hoechst Schering Agrevo Gmbh
Publication of IL112851A0 publication Critical patent/IL112851A0/xx
Publication of IL112851A publication Critical patent/IL112851A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/36—Racemisation of optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/301—Acyclic saturated acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
IL11285195A 1994-03-04 1995-03-02 Process for preparing ¬L¾-or ¬D¾-homoalanin-4-yl-(methyl) phosphonic acid and salts thereof by racemate resolution IL112851A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4407197A DE4407197A1 (de) 1994-03-04 1994-03-04 Verfahren zur Herstellung von /L/-Homoalanin-4-yl-(methyl)phosphinsäure und deren Salze durch Racematspaltung

Publications (2)

Publication Number Publication Date
IL112851A0 IL112851A0 (en) 1995-06-29
IL112851A true IL112851A (en) 2000-08-13

Family

ID=6511844

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11285195A IL112851A (en) 1994-03-04 1995-03-02 Process for preparing ¬L¾-or ¬D¾-homoalanin-4-yl-(methyl) phosphonic acid and salts thereof by racemate resolution

Country Status (19)

Country Link
US (2) US5767309A (Direct)
EP (1) EP0748325B1 (Direct)
JP (1) JP4303785B2 (Direct)
CN (1) CN1053669C (Direct)
AT (1) ATE176475T1 (Direct)
AU (1) AU704175B2 (Direct)
BR (1) BR9506986A (Direct)
CA (1) CA2184718A1 (Direct)
CZ (1) CZ260196A3 (Direct)
DE (2) DE4407197A1 (Direct)
ES (1) ES2128717T3 (Direct)
FI (1) FI963422A0 (Direct)
HU (1) HU215583B (Direct)
IL (1) IL112851A (Direct)
MX (1) MX9603873A (Direct)
TR (1) TR28265A (Direct)
TW (1) TW293012B (Direct)
WO (1) WO1995023805A1 (Direct)
ZA (1) ZA951779B (Direct)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100332399B1 (ko) * 1999-02-22 2002-04-13 김경호 메토프롤롤 라세미체로부터 메토프롤롤 에난티오머의 제조방법
DE19955283A1 (de) * 1999-11-17 2001-05-23 Aventis Res & Tech Gmbh & Co Verfahren zur enantioselektiven Gewinnung von Aminosäuren und Aminosäurederivaten unter Verwendung von Racemisierungskatalysatoren
US7879824B2 (en) 2001-07-31 2011-02-01 Dermal Research Laboratories, Inc. Methods of preventing or treating diseases and conditions using complex carbohydrates
US9834802B2 (en) * 2016-03-02 2017-12-05 Agrimetis, Llc Methods for making L-glufosinate
CN106188134B (zh) * 2016-07-01 2018-03-20 永农生物科学有限公司 一种l‑草铵膦或其盐的分离及精制方法
WO2018108794A1 (de) 2016-12-15 2018-06-21 Bayer Cropscience Aktiengesellschaft Verfahren zur herstellung von d-glufosinat oder dessen salzen unter verwendung von ephedrin
WO2018108797A1 (de) 2016-12-15 2018-06-21 Bayer Cropscience Aktiengesellschaft Verfahren zur herstellung von l-glufosinat oder dessen salzen unter verwendung von ephedrin
US11220521B2 (en) 2017-04-17 2022-01-11 Nahls Corporation Co., Ltd. Optically-active 2-amino-phosphonoalkane acid, optically-active 2-amino-phosphonoalkane acid salt, and hydrates of these
AU2018304177B2 (en) * 2017-07-18 2023-11-02 Basf Se Methods for the purification of L-glufosinate
CN110343676B (zh) 2018-04-03 2020-06-23 上海弈柯莱生物医药科技有限公司 一种l-谷氨酸脱氢酶突变体及其应用
CN110467580B (zh) * 2018-05-10 2020-11-13 华润赛科药业有限责任公司 雷西纳德轴手性对映体的拆分方法
CN112739822A (zh) 2018-09-05 2021-04-30 巴斯夫欧洲公司 改善l-草胺膦产率的方法
CN111072718A (zh) * 2018-10-19 2020-04-28 中国药科大学 一种l－草铵膦的制备方法
CN109369713A (zh) * 2018-12-18 2019-02-22 山东省农药科学研究院 一种精草铵膦酸水合物晶体及其制备方法
US12234254B2 (en) 2019-04-16 2025-02-25 Basf Se Methods for producing crystalline L-glufosinate ammonium monohydrate
CN111979208B (zh) 2019-05-23 2023-01-10 弈柯莱生物科技(上海)股份有限公司 一种l-谷氨酸脱氢酶突变体及其应用
US11555046B2 (en) 2020-07-31 2023-01-17 Upl Ltd Crystalline form of L-glufosinate ammonium salt and process for production thereof
TW202539517A (zh) * 2020-07-31 2025-10-16 印度商Ｕｐｌ有限公司 L-固殺草銨鹽之晶形及其生產程序
CN114805433B (zh) * 2021-05-13 2023-11-28 永农生物科学有限公司 不含结晶水的l-草铵膦铵盐晶体形式及固体粉末
CN117597026A (zh) * 2021-06-11 2024-02-23 Upl有限公司 一种用于获得l-草铵膦的方法
JP2025500792A (ja) 2021-12-10 2025-01-15 ビーエーエスエフ ソシエタス・ヨーロピア グルホシネート誘導体の酵素的脱カルバモイル化
AR127934A1 (es) 2021-12-10 2024-03-13 Basf Se Síntesis de glufosinato mediante el uso de un proceso basado en hidantoinasa
CN119325479A (zh) * 2022-06-10 2025-01-17 江苏七洲绿色科技研究院有限公司 L-草铵膦铵盐的结晶及其制备方法和应用
AU2024213094A1 (en) * 2023-01-25 2025-07-24 Vulpes Agricultural Corp. Optically active amino acid salts and method for their preparation
EP4669760A1 (en) 2023-02-23 2025-12-31 Basf Se PROCESS FOR PREPARING L-GLUFOSINATE FROM CYANHYDRIN OR CYANHYDRIN DERIVATIVES
TW202512923A (zh) 2023-06-13 2025-04-01 德商巴地斯顏料化工廠 使用基於醯胺酶之製程合成固殺草
WO2026015462A1 (en) * 2024-07-09 2026-01-15 Vulpes Agricultural Corp. Optically active tryptophan derivative glufosinate salts and preparation method

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3213106A (en) * 1961-11-16 1965-10-19 Ajinomoto Kk Process of racemizing optically active alpha acids
CH551945A (de) * 1970-07-16 1974-07-31 Ciba Geigy Ag Verfahren zur herstellung der (+)-(beta)-amino-(beta)-(3,4-dimethoxy-phenyl)-propionsaeure.
US4265654A (en) * 1977-12-28 1981-05-05 Meiji Seika Kaisha Ltd. Herbicidal compositions
US4401820A (en) * 1981-01-23 1983-08-30 Tanabe Seiyaku Co., Ltd. Process for racemizing optically active α-amino acids or a salt thereof
GB8421964D0 (en) * 1984-08-30 1984-10-03 Beecham Group Plc Chemical process
DE3542645A1 (de) * 1985-12-03 1987-06-04 Hoechst Ag Verfahren zur herstellung von l-homoalanin-4-yl(methyl)-phosphinsaeure sowie ihrer alkylester
DE3609818A1 (de) * 1986-03-22 1987-09-24 Hoechst Ag Verfahren zur herstellung von l-phosphinothricin(derivaten) sowie ihrer alkylester
DE3706022A1 (de) * 1987-02-25 1988-09-08 Hoechst Ag Verfahren zur racemisierung von optisch aktiver d-2-phenacetylamino-4-methylphosphinobuttersaeure
DE3817191A1 (de) * 1988-05-20 1989-11-30 Hoechst Ag Verfahren zur racemisierung von optisch aktiver d-2-n-phenacetylamino-4- methylphosphinobuttersaeure
DE3817956A1 (de) * 1988-05-27 1989-12-07 Hoechst Ag Verfahren zur herstellung phosphorhaltiger l-aminosaeuren sowie ihrer ester und n-derivate
DE3903446A1 (de) * 1989-02-06 1990-10-18 Hoechst Ag Verfahren zur enzymatischen trennung von 2-amino-4-methylphosphinobuttersaeurederivaten
DE3920570A1 (de) * 1989-06-23 1991-01-03 Hoechst Ag Verfahren zur isolierung von l-2-amino-4-methylphosphinobuttersaeure-ammoniumsalz aus einer enzymatischen transaminierungsloesung
DE3923650A1 (de) * 1989-07-18 1991-01-31 Hoechst Ag Verfahren zur gewinnung von l-2-amino-4-methylphosphinobuttersaeure-(salzen) durch elektrodialyse
IL114631A (en) * 1990-06-22 1998-12-06 Novartis Ag Anti-epileptic compositions containing gabab- antagonistic compounds
EP0499376A1 (en) * 1991-01-31 1992-08-19 Hoechst Celanese Corporation Precipitation-induced asymmetric transformation of chiral alpha-amino acids and salts thereof
TW353663B (en) * 1991-04-06 1999-03-01 Hoechst Ag Process for the preparation of phosphorus-containing L-amino acids, their derivatives and intermediates for this process
DE9202282U1 (de) * 1991-04-09 1992-04-30 Siemens AG, 8000 München Schiebeschalter
EP0530506B1 (de) * 1991-08-03 1996-05-01 Hoechst Schering AgrEvo GmbH Optisch aktive Omega-Halogen-2-amino-alkancarbonsäure-derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung optisch aktiver phosphorhaltiger Alpha-Aminosäuren
JPH05165305A (ja) * 1991-12-11 1993-07-02 Sharp Corp 帯電装置
IL104056A (en) * 1991-12-13 1997-02-18 Hoechst Ag Process for the preparation of L-phosphinothricin and its derivatives

Also Published As

Publication number Publication date
JP4303785B2 (ja) 2009-07-29
DE59505034D1 (de) 1999-03-18
ES2128717T3 (es) 1999-05-16
HUT75050A (en) 1997-03-28
AU1759595A (en) 1995-09-18
CA2184718A1 (en) 1995-09-08
HU215583B (hu) 1999-01-28
WO1995023805A1 (de) 1995-09-08
CN1143369A (zh) 1997-02-19
US5869668A (en) 1999-02-09
TR28265A (tr) 1996-04-09
FI963422A7 (fi) 1996-09-02
EP0748325A1 (de) 1996-12-18
ZA951779B (en) 1995-11-09
FI963422L (fi) 1996-09-02
DE4407197A1 (de) 1995-09-07
AU704175B2 (en) 1999-04-15
IL112851A0 (en) 1995-06-29
FI963422A0 (fi) 1996-09-02
CN1053669C (zh) 2000-06-21
ATE176475T1 (de) 1999-02-15
CZ260196A3 (en) 1997-02-12
EP0748325B1 (de) 1999-02-03
MX9603873A (es) 1997-03-29
JPH09509924A (ja) 1997-10-07
BR9506986A (pt) 1997-09-16
TW293012B (Direct) 1996-12-11
HU9602411D0 (en) 1996-11-28
US5767309A (en) 1998-06-16

Similar Documents

Publication Publication Date Title
IL112851A (en) Process for preparing ¬L¾-or ¬D¾-homoalanin-4-yl-(methyl) phosphonic acid and salts thereof by racemate resolution
WO1995023805B1 (de) Verfahren zur herstellung von [l]- oder [d]-homoalanin-4-yl-(methyl)phosphinsäure und deren salzen durch racematspaltung
DK0763010T3 (da) Enantioselektiv præparering af optisk ren albuterol
DE59908211D1 (de) Verfahren zur racematspaltung von 2-hydroxypropionsäuren
ATE147785T1 (de) Verfahren zur herstellung von beta-hydroxy-alpha- aminosäuren
DE59201373D1 (de) Verfahren zur Herstellung von L-Carnitin aus D,L-Carnitinnitrilsalzen.
ATE138414T1 (de) Verfahren zur herstellung von optisch aktiver 2- arylpropionsäure
FR2788271B1 (fr) Nouveau procede de preparation d'aminoacides chiraux
ATE342884T1 (de) Verfahren zur herstellung von geschützten dihydroxypropyl-trialkylammoniumsalzen und derivaten davon
CS9100417A2 (en) Method of amino acids' optically active amides preparation
DE69819538D1 (de) Verfahren zur verbesserung der optischen reinheit von 2r-[1-hydroxy-1-trifluormethyl-3-cyclopropylpropyn-2-yl]-4-chloranilin
DE69102767D1 (de) Verfahren zur umsetzung der r(-)(benzoyl-3 phenyl)-2 propionsäure zum isomer s(+).
DE59007604D1 (de) Verfahren zur Herstellung von R-(+)-3-Oxocycloalkancarbonsäureniederalkylestern.
ATE251097T1 (de) Verfahren zur racemisierung von n-acetyl-d(l)- alpha-aminocarbonsäuren
DE3855499D1 (de) Verfahren zur Bildung von Pflanzennährböden, sowie Anspritzmasse zur Durchführung des Verfahrens
ATE107364T1 (de) Verfahren zur herstellung von optisch aktiven 2- aryloxy- oder 2-arylthioalkansäuren.
FI914116A0 (fi) Menetelmä 2,2-dimetyylisyklopropaanikarboksyylihapon rasemaattipilkkomiseksi
ES8105779A1 (es) Un metodo para producir acido l-glutamico
JPS62164649A (ja) 光学活性２−（４−クロルフエニル）−３−メチル酪酸のラセミ化の方法
TH18940A (th) กรรมวิธีสำหรับการเตรียม กรด (l) หรือ (d)-โฮโมอะลานิน 4-อิล (เมธิล) ฟอสฟินิกและเกลือของกรดนั้นโดยการแยกสารผสมเรซิเมท

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees
KB Patent renewed
KB Patent renewed
EXP Patent expired