IL110086A - Process for preparing the history of antihistamines piperidine - Google Patents
Process for preparing the history of antihistamines piperidineInfo
- Publication number
- IL110086A IL110086A IL11008694A IL11008694A IL110086A IL 110086 A IL110086 A IL 110086A IL 11008694 A IL11008694 A IL 11008694A IL 11008694 A IL11008694 A IL 11008694A IL 110086 A IL110086 A IL 110086A
- Authority
- IL
- Israel
- Prior art keywords
- compound
- halo
- keto
- give
- appropriate
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
- C07C235/76—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C235/78—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/16—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same carbon atom of an acyclic carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/782—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic
- C07C49/792—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic containing rings other than six-membered aromatic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/794—Ketones containing a keto group bound to a six-membered aromatic ring having unsaturation outside an aromatic ring
- C07C49/798—Ketones containing a keto group bound to a six-membered aromatic ring having unsaturation outside an aromatic ring containing rings other than six-membered aromatic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
- C07C49/825—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups all hydroxy groups bound to the ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
- C07C49/83—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
- C07C49/835—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups having unsaturation outside an aromatic ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/86—Ketones containing a keto group bound to a six-membered aromatic ring containing —CHO groups
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/86—Unsaturated compounds containing keto groups containing six-membered aromatic rings and other rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/88—Unsaturated compounds containing keto groups containing halogen
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/007—Esters of unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL14361994A IL143619A (en) | 1993-06-25 | 1994-06-22 | Process for the preparation of anthistaminic piperidine derivatives |
IL14361394A IL143613A (en) | 1993-06-25 | 1994-06-22 | Process for the preparation of antihistaminic piperidine derivatives |
IL14360794A IL143607A (en) | 1993-06-25 | 1994-06-22 | Cyclopropyl ketone derivatives useful in the preparation of certain antihistaminic piperidine derivatives |
IL14360701A IL143607A0 (en) | 1993-06-25 | 2001-06-06 | Cyclopropyl ketone derivatives useful in the preparation of certain antihistaminic piperidine derivatives |
IL14361101A IL143611A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of piperidine derivatives |
IL14361901A IL143619A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
IL14360901A IL143609A0 (en) | 1993-06-25 | 2001-06-06 | Omega-halo phenylketone and phenylalcohol derivatives useful in the preparation of certain antihistaminic piperidine derivatives |
IL14361001A IL143610A0 (en) | 1993-06-25 | 2001-06-06 | Piperidine derivatives |
IL14361701A IL143617A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
IL14361501A IL143615A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
IL14361801A IL143618A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
IL14361201A IL143612A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
IL14361301A IL143613A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
IL14360801A IL143608A0 (en) | 1993-06-25 | 2001-06-06 | Omega-halo phenylketone derivatives useful in the preparation of certain antihistaminic piperidine derivatives |
IL14361401A IL143614A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
IL14361601A IL143616A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8269393A | 1993-06-25 | 1993-06-25 | |
US14408493A | 1993-10-27 | 1993-10-27 | |
US23746694A | 1994-05-11 | 1994-05-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL110086A0 IL110086A0 (en) | 1994-10-07 |
IL110086A true IL110086A (en) | 2001-09-13 |
Family
ID=27374315
Family Applications (20)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14361394A IL143613A (en) | 1993-06-25 | 1994-06-22 | Process for the preparation of antihistaminic piperidine derivatives |
IL14361994A IL143619A (en) | 1993-06-25 | 1994-06-22 | Process for the preparation of anthistaminic piperidine derivatives |
IL174850A IL174850A (en) | 1993-06-25 | 1994-06-22 | Compounds used in the preparation of a history of antihistamine piperidine |
IL11008694A IL110086A (en) | 1993-06-25 | 1994-06-22 | Process for preparing the history of antihistamines piperidine |
IL14360794A IL143607A (en) | 1993-06-25 | 1994-06-22 | Cyclopropyl ketone derivatives useful in the preparation of certain antihistaminic piperidine derivatives |
IL143611A IL143611A (en) | 1993-06-25 | 1994-06-22 | Process for the preparation of antihistaminic piperidine derivatives |
IL143612A IL143612A (en) | 1993-06-25 | 1994-06-22 | Process for the preparation of antihistaminic piperidine derivatives |
IL14361401A IL143614A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
IL14361601A IL143616A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
IL14361801A IL143618A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
IL14361201A IL143612A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
IL14361901A IL143619A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
IL14360801A IL143608A0 (en) | 1993-06-25 | 2001-06-06 | Omega-halo phenylketone derivatives useful in the preparation of certain antihistaminic piperidine derivatives |
IL14360901A IL143609A0 (en) | 1993-06-25 | 2001-06-06 | Omega-halo phenylketone and phenylalcohol derivatives useful in the preparation of certain antihistaminic piperidine derivatives |
IL14361101A IL143611A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of piperidine derivatives |
IL14361701A IL143617A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
IL14361501A IL143615A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
IL14361301A IL143613A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
IL14360701A IL143607A0 (en) | 1993-06-25 | 2001-06-06 | Cyclopropyl ketone derivatives useful in the preparation of certain antihistaminic piperidine derivatives |
IL14361001A IL143610A0 (en) | 1993-06-25 | 2001-06-06 | Piperidine derivatives |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14361394A IL143613A (en) | 1993-06-25 | 1994-06-22 | Process for the preparation of antihistaminic piperidine derivatives |
IL14361994A IL143619A (en) | 1993-06-25 | 1994-06-22 | Process for the preparation of anthistaminic piperidine derivatives |
IL174850A IL174850A (en) | 1993-06-25 | 1994-06-22 | Compounds used in the preparation of a history of antihistamine piperidine |
Family Applications After (16)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14360794A IL143607A (en) | 1993-06-25 | 1994-06-22 | Cyclopropyl ketone derivatives useful in the preparation of certain antihistaminic piperidine derivatives |
IL143611A IL143611A (en) | 1993-06-25 | 1994-06-22 | Process for the preparation of antihistaminic piperidine derivatives |
IL143612A IL143612A (en) | 1993-06-25 | 1994-06-22 | Process for the preparation of antihistaminic piperidine derivatives |
IL14361401A IL143614A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
IL14361601A IL143616A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
IL14361801A IL143618A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
IL14361201A IL143612A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
IL14361901A IL143619A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
IL14360801A IL143608A0 (en) | 1993-06-25 | 2001-06-06 | Omega-halo phenylketone derivatives useful in the preparation of certain antihistaminic piperidine derivatives |
IL14360901A IL143609A0 (en) | 1993-06-25 | 2001-06-06 | Omega-halo phenylketone and phenylalcohol derivatives useful in the preparation of certain antihistaminic piperidine derivatives |
IL14361101A IL143611A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of piperidine derivatives |
IL14361701A IL143617A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
IL14361501A IL143615A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
IL14361301A IL143613A0 (en) | 1993-06-25 | 2001-06-06 | A process for the preparation of antihistaminic piperidine derivatives |
IL14360701A IL143607A0 (en) | 1993-06-25 | 2001-06-06 | Cyclopropyl ketone derivatives useful in the preparation of certain antihistaminic piperidine derivatives |
IL14361001A IL143610A0 (en) | 1993-06-25 | 2001-06-06 | Piperidine derivatives |
Country Status (21)
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US (11) | US6242606B1 (fi) |
EP (5) | EP2261207A1 (fi) |
JP (3) | JP3712208B2 (fi) |
KR (1) | KR100333790B1 (fi) |
CN (3) | CN1168717C (fi) |
AT (1) | ATE230395T1 (fi) |
AU (2) | AU699559B2 (fi) |
CA (3) | CA2362339C (fi) |
DE (1) | DE69431954T2 (fi) |
DK (1) | DK0705245T3 (fi) |
ES (1) | ES2190442T3 (fi) |
FI (2) | FI114912B (fi) |
HK (2) | HK1032226A1 (fi) |
HU (1) | HU226037B1 (fi) |
IL (20) | IL143613A (fi) |
MX (4) | MXPA01007692A (fi) |
NO (3) | NO313191B1 (fi) |
NZ (1) | NZ267830A (fi) |
TW (1) | TW334420B (fi) |
WO (1) | WO1995000480A1 (fi) |
ZA (1) | ZA944380B (fi) |
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1994
- 1994-05-26 EP EP10177004A patent/EP2261207A1/en not_active Withdrawn
- 1994-05-26 CN CNB941930319A patent/CN1168717C/zh not_active Expired - Lifetime
- 1994-05-26 EP EP08008300A patent/EP1953142A1/en not_active Withdrawn
- 1994-05-26 AU AU70466/94A patent/AU699559B2/en not_active Expired
- 1994-05-26 DE DE69431954T patent/DE69431954T2/de not_active Expired - Lifetime
- 1994-05-26 JP JP50283195A patent/JP3712208B2/ja not_active Expired - Lifetime
- 1994-05-26 KR KR1019950705911A patent/KR100333790B1/ko not_active IP Right Cessation
- 1994-05-26 CA CA002362339A patent/CA2362339C/en not_active Expired - Lifetime
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- 1994-05-26 WO PCT/US1994/005982 patent/WO1995000480A1/en active IP Right Grant
- 1994-05-26 EP EP10177005A patent/EP2261208A1/en not_active Withdrawn
- 1994-05-26 DK DK94919264T patent/DK0705245T3/da active
- 1994-05-26 CA CA002362337A patent/CA2362337C/en not_active Expired - Lifetime
- 1994-05-26 CN CNB001010352A patent/CN1159277C/zh not_active Expired - Lifetime
- 1994-05-26 EP EP02012626A patent/EP1260504A1/en not_active Withdrawn
- 1994-05-26 HU HU9503705A patent/HU226037B1/hu unknown
- 1994-05-26 ES ES94919264T patent/ES2190442T3/es not_active Expired - Lifetime
- 1994-06-20 ZA ZA944380A patent/ZA944380B/xx unknown
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- 1994-06-22 IL IL14361394A patent/IL143613A/xx not_active IP Right Cessation
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- 1994-07-14 US US08/275,685 patent/US6242606B1/en not_active Expired - Lifetime
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1995
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- 1995-12-22 FI FI956248A patent/FI114912B/fi not_active IP Right Cessation
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1999
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- 2000-11-29 US US09/725,298 patent/US6340761B1/en not_active Expired - Fee Related
- 2000-11-29 US US09/725,291 patent/US6566526B2/en not_active Expired - Fee Related
- 2000-11-29 US US09/725,259 patent/US6552200B2/en not_active Expired - Fee Related
- 2000-12-01 US US09/726,625 patent/US6479663B2/en not_active Expired - Fee Related
- 2000-12-01 US US09/726,580 patent/US6555689B2/en not_active Expired - Fee Related
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- 2000-12-08 US US09/731,654 patent/US6559312B2/en not_active Expired - Fee Related
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2001
- 2001-03-28 US US09/818,966 patent/US6441179B1/en not_active Expired - Fee Related
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- 2001-04-20 HK HK01102808A patent/HK1032226A1/xx not_active IP Right Cessation
- 2001-06-06 IL IL14361401A patent/IL143614A0/xx unknown
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- 2001-06-06 IL IL14361801A patent/IL143618A0/xx unknown
- 2001-06-06 IL IL14361201A patent/IL143612A0/xx unknown
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- 2001-06-06 IL IL14360901A patent/IL143609A0/xx unknown
- 2001-06-06 IL IL14361101A patent/IL143611A0/xx unknown
- 2001-06-06 IL IL14361701A patent/IL143617A0/xx unknown
- 2001-06-06 IL IL14361501A patent/IL143615A0/xx unknown
- 2001-06-06 IL IL14361301A patent/IL143613A0/xx unknown
- 2001-06-06 IL IL14360701A patent/IL143607A0/xx unknown
- 2001-06-06 IL IL14361001A patent/IL143610A0/xx unknown
- 2001-07-30 MX MXPA01007692A patent/MXPA01007692A/es active IP Right Grant
- 2001-07-30 MX MXPA01007688A patent/MXPA01007688A/es active IP Right Grant
- 2001-07-30 MX MXPA01007687A patent/MXPA01007687A/es active IP Right Grant
- 2001-07-30 MX MXPA01007693A patent/MXPA01007693A/es active IP Right Grant
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2002
- 2002-05-03 NO NO20022129A patent/NO319850B1/no not_active IP Right Cessation
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2003
- 2003-02-12 US US10/364,641 patent/US6777555B2/en not_active Expired - Fee Related
- 2003-09-25 FI FI20031381A patent/FI119932B/fi not_active IP Right Cessation
- 2003-10-28 NO NO20034811A patent/NO319873B1/no not_active IP Right Cessation
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2005
- 2005-05-02 JP JP2005133801A patent/JP4384617B2/ja not_active Expired - Lifetime
- 2005-09-07 HK HK05107826A patent/HK1075884A1/xx not_active IP Right Cessation
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2008
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