PL3365327T3 - Sposób wytwarzania feksofenadyny i związki pośrednie stosowane w tym sposobie - Google Patents
Sposób wytwarzania feksofenadyny i związki pośrednie stosowane w tym sposobieInfo
- Publication number
- PL3365327T3 PL3365327T3 PL16784529T PL16784529T PL3365327T3 PL 3365327 T3 PL3365327 T3 PL 3365327T3 PL 16784529 T PL16784529 T PL 16784529T PL 16784529 T PL16784529 T PL 16784529T PL 3365327 T3 PL3365327 T3 PL 3365327T3
- Authority
- PL
- Poland
- Prior art keywords
- fexofenadine
- preparation
- intermediates used
- intermediates
- Prior art date
Links
- RWTNPBWLLIMQHL-UHFFFAOYSA-N fexofenadine Chemical compound C1=CC(C(C)(C(O)=O)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 RWTNPBWLLIMQHL-UHFFFAOYSA-N 0.000 title 1
- 229960003592 fexofenadine Drugs 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15191020 | 2015-10-22 | ||
| EP16784529.6A EP3365327B1 (en) | 2015-10-22 | 2016-10-21 | Process for the preparation of fexofenadine and of intermediates used therein |
| PCT/EP2016/075391 WO2017068129A1 (en) | 2015-10-22 | 2016-10-21 | Process for the preparation of fexofenadine and of intermediates used therein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3365327T3 true PL3365327T3 (pl) | 2020-05-18 |
Family
ID=54360053
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL16784529T PL3365327T3 (pl) | 2015-10-22 | 2016-10-21 | Sposób wytwarzania feksofenadyny i związki pośrednie stosowane w tym sposobie |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10696633B2 (pl) |
| EP (1) | EP3365327B1 (pl) |
| CN (1) | CN109071438B (pl) |
| CA (1) | CA3002425C (pl) |
| DK (1) | DK3365327T3 (pl) |
| ES (1) | ES2770341T3 (pl) |
| HR (1) | HRP20200106T1 (pl) |
| HU (1) | HUE047669T2 (pl) |
| PL (1) | PL3365327T3 (pl) |
| PT (1) | PT3365327T (pl) |
| RS (1) | RS59874B1 (pl) |
| WO (1) | WO2017068129A1 (pl) |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2804422A (en) | 1954-12-29 | 1957-08-27 | Wm S Merrell Co | Tranquilizing composition comprising alpha phenyl, alpha-(4-piperidyl)-benzyl alcohol and method of using same |
| US4254129A (en) | 1979-04-10 | 1981-03-03 | Richardson-Merrell Inc. | Piperidine derivatives |
| EP1026147B1 (en) * | 1993-06-24 | 2003-11-19 | Albany Molecular Research, Inc. | Compounds useful as intermediates in the production of piperidine derivatives |
| CA2166059C (en) | 1993-06-25 | 2005-08-16 | Richard Carl Krauss | Novel intermediates for the preparation of antihistaminic 4-diphenylmethyl/diphenylmethoxy piperidine derivatives |
| GB0018691D0 (en) * | 2000-07-28 | 2000-09-20 | Rolabo Sl | Process |
| US6743941B2 (en) | 2001-06-15 | 2004-06-01 | Aventis Pharma Deutschland Gmbh | Process for the production of piperidine derivatives |
| WO2003000658A1 (en) | 2001-06-25 | 2003-01-03 | Aurobindo Pharma Limited | PROCESS FOR THE PREPARATION OF A HIGHLY PURE PHARMACEUTICAL INTERMEDIATE, 4-(CYCLOPROPYLCARBONYL)-α,α-DIMETHYLPHENYLACETIC ACID |
| US7498345B2 (en) | 2004-09-17 | 2009-03-03 | Albany Molecular Research, Inc. | Process for production of piperidine derivatives |
| WO2007135693A2 (en) | 2006-05-18 | 2007-11-29 | Ind-Swift Laboratories Limited | Intermediates useful for the preparation of antihistaminic piperidine derivative |
| EP3247699B1 (en) * | 2015-01-22 | 2019-05-15 | Sanofi-Aventis Deutschland GmbH | Process for the production of 2-[4-(cyclopropanecarbonyl)phenyl]-2-methyl-propanenitrile |
-
2016
- 2016-10-21 US US15/769,661 patent/US10696633B2/en active Active
- 2016-10-21 CN CN201680061995.XA patent/CN109071438B/zh active Active
- 2016-10-21 CA CA3002425A patent/CA3002425C/en active Active
- 2016-10-21 PL PL16784529T patent/PL3365327T3/pl unknown
- 2016-10-21 HU HUE16784529A patent/HUE047669T2/hu unknown
- 2016-10-21 HR HRP20200106TT patent/HRP20200106T1/hr unknown
- 2016-10-21 PT PT167845296T patent/PT3365327T/pt unknown
- 2016-10-21 RS RS20200121A patent/RS59874B1/sr unknown
- 2016-10-21 ES ES16784529T patent/ES2770341T3/es active Active
- 2016-10-21 DK DK16784529.6T patent/DK3365327T3/da active
- 2016-10-21 EP EP16784529.6A patent/EP3365327B1/en active Active
- 2016-10-21 WO PCT/EP2016/075391 patent/WO2017068129A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP3365327A1 (en) | 2018-08-29 |
| HUE047669T2 (hu) | 2020-05-28 |
| PT3365327T (pt) | 2020-02-06 |
| CA3002425C (en) | 2023-10-17 |
| EP3365327B1 (en) | 2019-11-20 |
| DK3365327T3 (da) | 2020-02-24 |
| ES2770341T3 (es) | 2020-07-01 |
| US10696633B2 (en) | 2020-06-30 |
| CN109071438B (zh) | 2023-02-21 |
| CA3002425A1 (en) | 2017-04-27 |
| US20180297951A1 (en) | 2018-10-18 |
| WO2017068129A1 (en) | 2017-04-27 |
| RS59874B1 (sr) | 2020-03-31 |
| HRP20200106T1 (hr) | 2020-04-03 |
| CN109071438A (zh) | 2018-12-21 |
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