DK1026147T3 - Forbindelser, der er anvendelige som mellemprodukter i fremstillingen af piperidinderivater - Google Patents

Forbindelser, der er anvendelige som mellemprodukter i fremstillingen af piperidinderivater

Info

Publication number
DK1026147T3
DK1026147T3 DK00200419T DK00200419T DK1026147T3 DK 1026147 T3 DK1026147 T3 DK 1026147T3 DK 00200419 T DK00200419 T DK 00200419T DK 00200419 T DK00200419 T DK 00200419T DK 1026147 T3 DK1026147 T3 DK 1026147T3
Authority
DK
Denmark
Prior art keywords
intermediates
preparation
compounds useful
piperidine derivatives
compounds
Prior art date
Application number
DK00200419T
Other languages
English (en)
Inventor
Ambra Thomas E D
Original Assignee
Albany Molecular Res Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22176189&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1026147(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Albany Molecular Res Inc filed Critical Albany Molecular Res Inc
Application granted granted Critical
Publication of DK1026147T3 publication Critical patent/DK1026147T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/86—Unsaturated compounds containing keto groups containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK00200419T 1993-06-24 1994-06-21 Forbindelser, der er anvendelige som mellemprodukter i fremstillingen af piperidinderivater DK1026147T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8310293A 1993-06-24 1993-06-24

Publications (1)

Publication Number Publication Date
DK1026147T3 true DK1026147T3 (da) 2004-03-22

Family

ID=22176189

Family Applications (3)

Application Number Title Priority Date Filing Date
DK00200419T DK1026147T3 (da) 1993-06-24 1994-06-21 Forbindelser, der er anvendelige som mellemprodukter i fremstillingen af piperidinderivater
DK94920762T DK0703902T3 (da) 1993-06-24 1994-06-21 Fremgangsmåde til fremstilling af piperidinderivater
DK03077245T DK1369409T3 (da) 1993-06-24 1994-06-21 Fremgangsmåde til fremstilling af forbindelser, der er anvendelige som mellemprodukter

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK94920762T DK0703902T3 (da) 1993-06-24 1994-06-21 Fremgangsmåde til fremstilling af piperidinderivater
DK03077245T DK1369409T3 (da) 1993-06-24 1994-06-21 Fremgangsmåde til fremstilling af forbindelser, der er anvendelige som mellemprodukter

Country Status (16)

Country Link
US (9) US5589487A (da)
EP (4) EP1026147B1 (da)
JP (4) JP3034047B2 (da)
KR (2) KR100387348B1 (da)
AT (3) ATE174589T1 (da)
AU (1) AU670004B2 (da)
CA (1) CA2147126C (da)
DE (3) DE69415319T2 (da)
DK (3) DK1026147T3 (da)
ES (3) ES2129130T3 (da)
FI (1) FI109691B (da)
HU (1) HU226559B1 (da)
NO (2) NO308599B1 (da)
NZ (1) NZ268513A (da)
PT (2) PT1369409E (da)
WO (1) WO1995000482A1 (da)

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HU226559B1 (en) 1993-06-24 2009-03-30 Amr Technology Process for the production of piperidine derivatives
US20020007068A1 (en) 1999-07-16 2002-01-17 D'ambra Thomas E. Piperidine derivatives and process for their production
CN1275916C (zh) 1993-06-25 2006-09-20 阿温蒂斯公司 用于制备抗组胺哌啶衍生物的新中间体
US20030045722A1 (en) * 1994-05-18 2003-03-06 Henton Daniel R. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
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Also Published As

Publication number Publication date
DE69415319D1 (de) 1999-01-28
JP4124998B2 (ja) 2008-07-23
ATE174589T1 (de) 1999-01-15
NZ268513A (en) 1996-09-25
JP2002212166A (ja) 2002-07-31
HUT73235A (en) 1996-07-29
US20080227983A1 (en) 2008-09-18
DK1369409T3 (da) 2006-08-14
DE69434696T2 (de) 2006-11-16
PT1026147E (pt) 2004-04-30
AU7174894A (en) 1995-01-17
EP0703902A4 (da) 1996-04-10
JPH11236373A (ja) 1999-08-31
EP1369409A1 (en) 2003-12-10
EP1369409B1 (en) 2006-04-05
EP0723958A1 (en) 1996-07-31
EP0703902B1 (en) 1998-12-16
ATE322473T1 (de) 2006-04-15
CA2147126C (en) 1999-08-24
ES2129130T3 (es) 1999-06-01
EP1026147A1 (en) 2000-08-09
CA2147126A1 (en) 1995-01-05
NO994582D0 (no) 1999-09-21
US20060241303A1 (en) 2006-10-26
US7238834B2 (en) 2007-07-03
NO994582L (no) 1995-12-12
US20060052610A1 (en) 2006-03-09
ES2261871T3 (es) 2006-11-16
EP1026147B1 (en) 2003-11-19
JP3195297B2 (ja) 2001-08-06
ATE254594T1 (de) 2003-12-15
ES2211444T3 (es) 2004-07-16
NO955023L (no) 1995-12-12
US5994549A (en) 1999-11-30
AU670004B2 (en) 1996-06-27
WO1995000482A1 (en) 1995-01-05
US5750703A (en) 1998-05-12
DE69415319T2 (de) 1999-06-10
FI109691B (fi) 2002-09-30
HU226559B1 (en) 2009-03-30
US5589487A (en) 1996-12-31
FI956270A (fi) 1995-12-27
NO955023D0 (no) 1995-12-12
KR960703398A (ko) 1996-08-17
KR100387348B1 (ko) 2003-06-12
KR100387347B1 (ko) 2003-11-28
US7390906B2 (en) 2008-06-24
DK0703902T3 (da) 1999-08-23
JPH08511806A (ja) 1996-12-10
NO308599B1 (no) 2000-10-02
JP2001031650A (ja) 2001-02-06
FI956270A0 (fi) 1995-12-27
EP0703902A1 (en) 1996-04-03
US5578610A (en) 1996-11-26
DE69433346D1 (de) 2003-12-24
US5663412A (en) 1997-09-02
JP3034047B2 (ja) 2000-04-17
JP3658291B2 (ja) 2005-06-08
DE69433346T2 (de) 2004-09-09
HU9503719D0 (en) 1996-02-28
PT1369409E (pt) 2006-08-31
US5581011A (en) 1996-12-03
DE69434696D1 (de) 2006-05-18

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