PT3365327T - Processo para a preparação de fexofenadina e de intermediários usados no mesmo - Google Patents
Processo para a preparação de fexofenadina e de intermediários usados no mesmoInfo
- Publication number
- PT3365327T PT3365327T PT167845296T PT16784529T PT3365327T PT 3365327 T PT3365327 T PT 3365327T PT 167845296 T PT167845296 T PT 167845296T PT 16784529 T PT16784529 T PT 16784529T PT 3365327 T PT3365327 T PT 3365327T
- Authority
- PT
- Portugal
- Prior art keywords
- fexofenadine
- preparation
- intermediates used
- intermediates
- Prior art date
Links
- RWTNPBWLLIMQHL-UHFFFAOYSA-N fexofenadine Chemical compound C1=CC(C(C)(C(O)=O)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 RWTNPBWLLIMQHL-UHFFFAOYSA-N 0.000 title 1
- 229960003592 fexofenadine Drugs 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15191020 | 2015-10-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3365327T true PT3365327T (pt) | 2020-02-06 |
Family
ID=54360053
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT167845296T PT3365327T (pt) | 2015-10-22 | 2016-10-21 | Processo para a preparação de fexofenadina e de intermediários usados no mesmo |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10696633B2 (pt) |
| EP (1) | EP3365327B1 (pt) |
| CN (1) | CN109071438B (pt) |
| CA (1) | CA3002425C (pt) |
| DK (1) | DK3365327T3 (pt) |
| ES (1) | ES2770341T3 (pt) |
| HR (1) | HRP20200106T1 (pt) |
| HU (1) | HUE047669T2 (pt) |
| PL (1) | PL3365327T3 (pt) |
| PT (1) | PT3365327T (pt) |
| RS (1) | RS59874B1 (pt) |
| WO (1) | WO2017068129A1 (pt) |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2804422A (en) | 1954-12-29 | 1957-08-27 | Wm S Merrell Co | Tranquilizing composition comprising alpha phenyl, alpha-(4-piperidyl)-benzyl alcohol and method of using same |
| US4254129A (en) | 1979-04-10 | 1981-03-03 | Richardson-Merrell Inc. | Piperidine derivatives |
| DK1026147T3 (da) | 1993-06-24 | 2004-03-22 | Albany Molecular Res Inc | Forbindelser, der er anvendelige som mellemprodukter i fremstillingen af piperidinderivater |
| HU226037B1 (en) * | 1993-06-25 | 2008-03-28 | Aventis Inc | Process for producing antihistaminic 4-diphenylmethyl/diphenylmethoxy piperidine derivatives and novel intermediates |
| GB0018691D0 (en) | 2000-07-28 | 2000-09-20 | Rolabo Sl | Process |
| US6743941B2 (en) | 2001-06-15 | 2004-06-01 | Aventis Pharma Deutschland Gmbh | Process for the production of piperidine derivatives |
| SK712003A3 (en) | 2001-06-25 | 2003-12-02 | Aurobindo Pharma Ltd | Process for the preparation of 4-(cyclopropylcarbonyl)-alpha, alpha-dimethylphenylacetic acid |
| US7498345B2 (en) | 2004-09-17 | 2009-03-03 | Albany Molecular Research, Inc. | Process for production of piperidine derivatives |
| WO2007135693A2 (en) | 2006-05-18 | 2007-11-29 | Ind-Swift Laboratories Limited | Intermediates useful for the preparation of antihistaminic piperidine derivative |
| US10336698B2 (en) * | 2015-01-22 | 2019-07-02 | Sanofi-Aventis Deutschland Gmbh | Process for the production of 2-[4-(cyclopropanecarbonyl)phenyl]-2-methyl-propanenitrile |
-
2016
- 2016-10-21 PT PT167845296T patent/PT3365327T/pt unknown
- 2016-10-21 PL PL16784529T patent/PL3365327T3/pl unknown
- 2016-10-21 HR HRP20200106TT patent/HRP20200106T1/hr unknown
- 2016-10-21 ES ES16784529T patent/ES2770341T3/es active Active
- 2016-10-21 DK DK16784529.6T patent/DK3365327T3/da active
- 2016-10-21 CA CA3002425A patent/CA3002425C/en active Active
- 2016-10-21 EP EP16784529.6A patent/EP3365327B1/en active Active
- 2016-10-21 CN CN201680061995.XA patent/CN109071438B/zh active Active
- 2016-10-21 US US15/769,661 patent/US10696633B2/en active Active
- 2016-10-21 HU HUE16784529A patent/HUE047669T2/hu unknown
- 2016-10-21 RS RS20200121A patent/RS59874B1/sr unknown
- 2016-10-21 WO PCT/EP2016/075391 patent/WO2017068129A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2017068129A1 (en) | 2017-04-27 |
| PL3365327T3 (pl) | 2020-05-18 |
| DK3365327T3 (da) | 2020-02-24 |
| CN109071438B (zh) | 2023-02-21 |
| US10696633B2 (en) | 2020-06-30 |
| HRP20200106T1 (hr) | 2020-04-03 |
| CA3002425A1 (en) | 2017-04-27 |
| RS59874B1 (sr) | 2020-03-31 |
| CA3002425C (en) | 2023-10-17 |
| CN109071438A (zh) | 2018-12-21 |
| ES2770341T3 (es) | 2020-07-01 |
| HUE047669T2 (hu) | 2020-05-28 |
| US20180297951A1 (en) | 2018-10-18 |
| EP3365327B1 (en) | 2019-11-20 |
| EP3365327A1 (en) | 2018-08-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL287140A (en) | A process for the preparation of polyethylene glycol-converted pharmaceutical binders and their intermediates | |
| SI3380530T1 (sl) | Izboljšan postopek za pripravo sugamadeksa in njegovih intermediatov | |
| SI3433285T1 (sl) | Izboljšan postopek za pripravo sugamadeksa | |
| ZA201706795B (en) | Process for the preparation of dicycloplatin | |
| ZA202003590B (en) | Process for the preparation of opicapone and intermediates thereof | |
| IL259454B (en) | New process and intermediates | |
| IL274142A (en) | A process for the preparation of sanicriviroc and related analogs | |
| EP3189053A4 (en) | An improved process for the preparation of apixaban and intermediates thereof | |
| IL248267B (en) | A process for preparing converted cycloserines | |
| EP3212620A4 (en) | Process for the preparation of apixaban and intermediates thereof | |
| HRP20190403T1 (hr) | Postupak izrade lakozamida | |
| ZA201608823B (en) | Processes for the preparation of azd5363 and novel intermediate used therein | |
| IL247443B (en) | Process for the preparation of 5-fluorotryptophol | |
| IL255819A (en) | An improved process for the preparation of sofosbuvir and intermediates | |
| IL248139A0 (en) | Preparation of microelectrodes | |
| HUP1400543A2 (hu) | Eljárás és köztitermék apixaban elõállítására | |
| IL253077A0 (en) | Process and intermediates for the preparation of Fermpanel | |
| ZA201701973B (en) | Process for the preparation of halo-substituted trifluoroacetophenones | |
| GB2564185B (en) | Process for the preparation of derivatives of benzodioxole | |
| HUP1500647A2 (en) | Intermediate of baricitinib and process for its preparation | |
| IL237572A0 (en) | Process and intermediates for the preparation of dastinib | |
| PL3365327T3 (pl) | Sposób wytwarzania feksofenadyny i związki pośrednie stosowane w tym sposobie | |
| SI3230268T1 (sl) | Proces za pripravo tetrakonazola | |
| PL3075724T3 (pl) | Stała postać agomelatyny |