IL108885A - Benzoxazine derivatives and pharmaceutical compositions containing them - Google Patents
Benzoxazine derivatives and pharmaceutical compositions containing themInfo
- Publication number
- IL108885A IL108885A IL108885A IL10888594A IL108885A IL 108885 A IL108885 A IL 108885A IL 108885 A IL108885 A IL 108885A IL 10888594 A IL10888594 A IL 10888594A IL 108885 A IL108885 A IL 108885A
- Authority
- IL
- Israel
- Prior art keywords
- formula
- group
- compound
- tetrahydro
- produce
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9302659A FR2702477B1 (fr) | 1993-03-08 | 1993-03-08 | Dérivés de benzoxazine, leur préparation et leur application en thérapeutique. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL108885A0 IL108885A0 (en) | 1994-06-24 |
| IL108885A true IL108885A (en) | 1998-02-22 |
Family
ID=9444751
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL108885A IL108885A (en) | 1993-03-08 | 1994-03-07 | Benzoxazine derivatives and pharmaceutical compositions containing them |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5447928A (cs) |
| EP (1) | EP0614893B1 (cs) |
| JP (1) | JPH0710852A (cs) |
| CN (1) | CN1099032A (cs) |
| AT (1) | ATE166648T1 (cs) |
| AU (1) | AU673226B2 (cs) |
| CA (1) | CA2117122A1 (cs) |
| CZ (1) | CZ284789B6 (cs) |
| DE (1) | DE69410509T2 (cs) |
| DK (1) | DK0614893T3 (cs) |
| ES (1) | ES2119099T3 (cs) |
| FI (1) | FI941068A7 (cs) |
| FR (1) | FR2702477B1 (cs) |
| HU (1) | HUT70539A (cs) |
| IL (1) | IL108885A (cs) |
| NO (1) | NO300542B1 (cs) |
| NZ (1) | NZ260039A (cs) |
| RU (1) | RU2130020C1 (cs) |
| SK (1) | SK27494A3 (cs) |
| TW (1) | TW302362B (cs) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1109880A (zh) * | 1994-02-03 | 1995-10-11 | 合成实验室公司 | 3-(2-氨基乙基)-4-[3-(三氟甲基)苯甲酰基]-3，4-二氢-2h-1，4-苯并噁嗪衍生物、制备及其应用 |
| IL125658A0 (en) | 1997-08-18 | 1999-04-11 | Hoffmann La Roche | Ccr-3 receptor antagonists |
| US6339087B1 (en) | 1997-08-18 | 2002-01-15 | Syntex (U.S.A.) Llc | Cyclic amine derivatives-CCR-3 receptor antagonists |
| US6296833B1 (en) | 1998-01-30 | 2001-10-02 | The Brigham And Women's Hospital, Inc. | Human calcium-sensing receptor in the detection and treatment of cancer |
| TW472491B (en) * | 1999-03-19 | 2002-01-11 | Seiko Epson Corp | Projection system and projector |
| US6355648B1 (en) * | 1999-05-04 | 2002-03-12 | American Home Products Corporation | Thio-oxindole derivatives |
| US6509334B1 (en) * | 1999-05-04 | 2003-01-21 | American Home Products Corporation | Cyclocarbamate derivatives as progesterone receptor modulators |
| US6391907B1 (en) | 1999-05-04 | 2002-05-21 | American Home Products Corporation | Indoline derivatives |
| US6358948B1 (en) | 1999-05-04 | 2002-03-19 | American Home Products Corporation | Quinazolinone and benzoxazine derivatives as progesterone receptor modulators |
| UA73119C2 (en) | 2000-04-19 | 2005-06-15 | American Home Products Corpoir | Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors |
| EP1777225A4 (en) * | 2004-07-15 | 2009-06-24 | Japan Tobacco Inc | FUSED BENZAMIDE COMPOUND AND INHIBITOR OF VANILLOID RECEPTOR 1 (VR1) ACTIVITY |
| JP2008514703A (ja) * | 2004-09-29 | 2008-05-08 | ポートラ ファーマシューティカルズ， インコーポレイテッド | 置換２ｈ−１，３−ベンゾオキサジン−４（３ｈ）−オン |
| BRPI0516754A (pt) * | 2004-09-30 | 2008-09-16 | Hoffmann La Roche | usos e derivados de benzoxazina e quinoxalina |
| AR051780A1 (es) * | 2004-11-29 | 2007-02-07 | Japan Tobacco Inc | Compuestos en anillo fusionados que contienen nitrogeno y utilizacion de los mismos |
| HU230826B1 (hu) | 2014-11-19 | 2018-07-30 | Richter Gedeon Nyrt. | Eljárás benzazepin származékok előállítására |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1287584B (de) * | 1962-07-04 | 1969-01-23 | Thomae Gmbh Dr K | Verfahren zur Herstellung von 2, 3-Dihydro-1, 4-benzoxazinderivaten |
| SU1321373A3 (ru) * | 1985-03-07 | 1987-06-30 | Варнер-Ламберт Компани (Фирма) | Способ получени @ -(2,6-дизамещенных ароматических)- @ -пиридилмочевин или их фармацевтически приемлемых кислотно-аддитивных солей |
| JPS61215381A (ja) * | 1985-03-22 | 1986-09-25 | Ube Ind Ltd | ベンゾオキサジン誘導体および除草剤 |
| GB8803419D0 (en) * | 1988-02-15 | 1988-03-16 | Erba Carlo Spa | 1 4-benzoxazine & 1 4-benzothiazine derivatives & process for their preparation |
| AU638154B2 (en) * | 1990-10-04 | 1993-06-17 | Suntory Limited | Benzoxazine derivative and herbicide containing same as an active ingredient |
| DE4037427A1 (de) * | 1990-11-24 | 1992-05-27 | Kali Chemie Pharma Gmbh | Heterocyclisch substituierte piperazinoalkylbenzoxazin und -thiazin-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
-
1993
- 1993-03-08 FR FR9302659A patent/FR2702477B1/fr not_active Expired - Fee Related
-
1994
- 1994-02-23 EP EP94400382A patent/EP0614893B1/fr not_active Expired - Lifetime
- 1994-02-23 DE DE69410509T patent/DE69410509T2/de not_active Expired - Fee Related
- 1994-02-23 DK DK94400382T patent/DK0614893T3/da active
- 1994-02-23 ES ES94400382T patent/ES2119099T3/es not_active Expired - Lifetime
- 1994-02-23 AT AT94400382T patent/ATE166648T1/de not_active IP Right Cessation
- 1994-02-24 US US08/201,233 patent/US5447928A/en not_active Expired - Fee Related
- 1994-03-05 RU RU94007350A patent/RU2130020C1/ru active
- 1994-03-07 SK SK274-94A patent/SK27494A3/sk unknown
- 1994-03-07 TW TW083101951A patent/TW302362B/zh active
- 1994-03-07 CA CA002117122A patent/CA2117122A1/en not_active Abandoned
- 1994-03-07 NO NO940788A patent/NO300542B1/no unknown
- 1994-03-07 CN CN94102625A patent/CN1099032A/zh active Pending
- 1994-03-07 JP JP6035758A patent/JPH0710852A/ja active Pending
- 1994-03-07 HU HU9400671A patent/HUT70539A/hu unknown
- 1994-03-07 IL IL108885A patent/IL108885A/en not_active IP Right Cessation
- 1994-03-07 NZ NZ260039A patent/NZ260039A/en unknown
- 1994-03-07 AU AU57586/94A patent/AU673226B2/en not_active Ceased
- 1994-03-07 CZ CZ94516A patent/CZ284789B6/cs unknown
- 1994-03-07 FI FI941068A patent/FI941068A7/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2119099T3 (es) | 1998-10-01 |
| US5447928A (en) | 1995-09-05 |
| EP0614893B1 (fr) | 1998-05-27 |
| HUT70539A (en) | 1995-10-30 |
| CN1099032A (zh) | 1995-02-22 |
| AU673226B2 (en) | 1996-10-31 |
| NO940788L (no) | 1994-09-09 |
| FR2702477B1 (fr) | 1995-04-28 |
| ATE166648T1 (de) | 1998-06-15 |
| DE69410509T2 (de) | 1999-01-28 |
| CZ51694A3 (en) | 1994-10-19 |
| CZ284789B6 (cs) | 1999-03-17 |
| SK27494A3 (en) | 1995-03-08 |
| DE69410509D1 (de) | 1998-07-02 |
| CA2117122A1 (en) | 1994-09-09 |
| FI941068A0 (fi) | 1994-03-07 |
| AU5758694A (en) | 1994-09-15 |
| FR2702477A1 (fr) | 1994-09-16 |
| NZ260039A (en) | 1995-06-27 |
| FI941068A7 (fi) | 1994-09-09 |
| EP0614893A1 (fr) | 1994-09-14 |
| DK0614893T3 (da) | 1999-03-22 |
| TW302362B (cs) | 1997-04-11 |
| HU9400671D0 (en) | 1994-06-28 |
| NO940788D0 (no) | 1994-03-07 |
| RU2130020C1 (ru) | 1999-05-10 |
| NO300542B1 (no) | 1997-06-16 |
| JPH0710852A (ja) | 1995-01-13 |
| IL108885A0 (en) | 1994-06-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP3630755B1 (en) | 5-methyl-1,3,4-oxadiazol-2-yl compounds | |
| FI90241B (fi) | Menetelmä terapeuttisesti aktiivisen S(-)-9-halogeeni-3-alkyyli-10-(4-alkyylipiperatsinyyli)-7-okso-2,3-dihydro-7H-pyrido/1,2,3-de//1,4/bentsoksatsiini-6-karboksyylihapon valmistamiseksi | |
| IL108885A (en) | Benzoxazine derivatives and pharmaceutical compositions containing them | |
| EP0839136A1 (en) | BENZO[g]QUINOLINE DERIVATIVES | |
| KR101386387B1 (ko) | 트랜스-1-((1ｒ,3ｓ)-6-클로로-3-페닐인단-1-일)-3,3-디메틸피페라진의 결정성 염기 | |
| NZ230959A (en) | Piperazinylethyl-substituted quinolinones and pharmaceutical compositions | |
| AU2010340745B2 (en) | Sulfone compounds as 5-HT6 receptor ligands | |
| TWI421079B (zh) | 二苯并〔ｂ，ｆ〕〔１，４〕氧氮呯化合物 | |
| CA2615897A1 (en) | Compounds and methods for treatment of amyloid-beta-peptide related disorders | |
| NO171786B (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive isokinolinderivater | |
| US5550125A (en) | 3-(2-aminomethyl)-4-[3-trifluoromethyl)benzoyl]-3-4 dihydro-2h-1,4-benzoxazine derivatives and their therapeutic application | |
| FR2758329A1 (fr) | Derives d'imidazole-4-butane boronique, leur preparation et leur utilisation en therapeutique | |
| FI112214B (fi) | Pyridatsinonijohdannaisia | |
| US5641785A (en) | Oxazoloquinolinone derivatives, their preparation and their therapeutic application as inhibitors of monoamine oxidase | |
| JP3637974B2 (ja) | ピロリジン誘導体 | |
| JP4565747B2 (ja) | テトラヒドロイソキノリンアルカノール誘導体及びそれを含む薬学的組成物 | |
| WO1991011434A1 (fr) | Derive de bicyclolactame | |
| NZ754849A (en) | N-[4-fluoro-5-[[(2s,4s)-2-methyl-4-[(5-methyl-1,2,4-oxadiazol-3-yl)methoxy]-1-piperidyl]methyl]thiazol-2-yl]acetamide as oga inhibitor | |
| NZ754849B2 (en) | N-[4-fluoro-5-[[(2s,4s)-2-methyl-4-[(5-methyl-1,2,4-oxadiazol-3-yl)methoxy]-1-piperidyl]methyl]thiazol-2-yl]acetamide as oga inhibitor | |
| AU2006272049A1 (en) | Substituted piperidine derivatives as somatostatin SST1 receptor antagonists | |
| MXPA99006064A (en) | Acid-addition salts of optically active piperidine compound and process for producing the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| RH | Patent void |