IL108112A - Combination of cholesterol biosynthesis inhibitor and beta-lactam cholesterol absorption inhibitor absorption inhibitor - Google Patents

Combination of cholesterol biosynthesis inhibitor and beta-lactam cholesterol absorption inhibitor absorption inhibitor

Info

Publication number
IL108112A
IL108112A IL10811293A IL10811293A IL108112A IL 108112 A IL108112 A IL 108112A IL 10811293 A IL10811293 A IL 10811293A IL 10811293 A IL10811293 A IL 10811293A IL 108112 A IL108112 A IL 108112A
Authority
IL
Israel
Prior art keywords
phenyl
cholesterol
inhibitor
lower alkyl
heteroaryl
Prior art date
Application number
IL10811293A
Other languages
English (en)
Hebrew (he)
Other versions
IL108112A0 (en
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of IL108112A0 publication Critical patent/IL108112A0/xx
Publication of IL108112A publication Critical patent/IL108112A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL10811293A 1992-12-23 1993-12-21 Combination of cholesterol biosynthesis inhibitor and beta-lactam cholesterol absorption inhibitor absorption inhibitor IL108112A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US99548892A 1992-12-23 1992-12-23

Publications (2)

Publication Number Publication Date
IL108112A0 IL108112A0 (en) 1994-04-12
IL108112A true IL108112A (en) 1999-11-30

Family

ID=25541876

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10811293A IL108112A (en) 1992-12-23 1993-12-21 Combination of cholesterol biosynthesis inhibitor and beta-lactam cholesterol absorption inhibitor absorption inhibitor

Country Status (32)

Country Link
US (1) US5661145A (fr)
EP (1) EP0675714B1 (fr)
JP (1) JP3992728B2 (fr)
KR (1) KR100306936B1 (fr)
CN (1) CN1090479C (fr)
AT (1) ATE175872T1 (fr)
AU (1) AU680864B2 (fr)
CA (1) CA2152351C (fr)
CZ (1) CZ287125B6 (fr)
DE (1) DE69323213T2 (fr)
DK (1) DK0675714T3 (fr)
EE (1) EE03383B1 (fr)
ES (1) ES2128552T3 (fr)
FI (1) FI952916A0 (fr)
GR (1) GR3029405T3 (fr)
HR (1) HRP931515B1 (fr)
HU (1) HU221724B1 (fr)
IL (1) IL108112A (fr)
LT (1) LT3300B (fr)
LV (1) LV10919B (fr)
MX (1) MX9308053A (fr)
MY (1) MY109538A (fr)
NO (1) NO311325B1 (fr)
NZ (1) NZ259790A (fr)
PL (1) PL174128B1 (fr)
SG (1) SG45147A1 (fr)
SI (1) SI9300677A (fr)
SK (1) SK281173B6 (fr)
TW (1) TW319698B (fr)
WO (1) WO1994014433A1 (fr)
YU (1) YU49060B (fr)
ZA (1) ZA939552B (fr)

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US6593078B1 (en) 1999-04-16 2003-07-15 Schering Corporation Use of azetidinone compounds
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DE60206365T2 (de) 2001-03-28 2006-07-06 Schering Corporation, Kenilworth Verfahren für die enantioselektive synthese von azetidinon-zwischenprodukten
MXPA04002572A (es) * 2001-09-21 2004-05-31 Schering Corp Metodos para el tratamiento o prevencion de inflamacion vascular usando inhibidores de absorcion de esterol.
CA2460340C (fr) * 2001-09-21 2011-02-15 Schering Corporation Methodes et combinaisons therapeutiques utiles pour le traitement du xanthome effectue avec des inhibiteurs d'absorption du sterol
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EP1810971B1 (fr) * 2003-03-07 2013-12-25 Merck Sharp & Dohme Corp. Composés d'azetidinone substitués, formulations et utilisations de ceux-ci pour traiter l'hypercholestérolémie
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US4983597A (en) * 1989-08-31 1991-01-08 Merck & Co., Inc. Beta-lactams as anticholesterolemic agents
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PL2807099T3 (pl) 2012-01-26 2017-08-31 Intralot S.A. - Integrated Lottery Systems And Services Sposoby i układy do wydawania

Also Published As

Publication number Publication date
US5661145A (en) 1997-08-26
MY109538A (en) 1997-02-28
SK281173B6 (sk) 2000-12-11
CN1095591A (zh) 1994-11-30
HU9501854D0 (en) 1995-08-28
SK78395A3 (en) 1996-05-08
FI952916A (fi) 1995-06-14
JP3992728B2 (ja) 2007-10-17
EE9400341A (et) 1996-04-15
SG45147A1 (en) 1998-01-16
HUT72081A (en) 1996-03-28
ES2128552T3 (es) 1999-05-16
HRP931515B1 (en) 2000-02-29
PL309636A1 (en) 1995-10-30
IL108112A0 (en) 1994-04-12
LV10919B (en) 1996-04-20
CZ287125B6 (en) 2000-09-13
NO311325B1 (no) 2001-11-19
PL174128B1 (pl) 1998-06-30
EP0675714A1 (fr) 1995-10-11
TW319698B (fr) 1997-11-11
NO952529D0 (no) 1995-06-23
HU221724B1 (hu) 2002-12-28
WO1994014433A1 (fr) 1994-07-07
SI9300677A (en) 1994-09-30
JPH08505141A (ja) 1996-06-04
AU680864B2 (en) 1997-08-14
GR3029405T3 (en) 1999-05-28
MX9308053A (es) 1994-06-30
AU5872094A (en) 1994-07-19
YU49060B (sh) 2003-08-29
NO952529L (no) 1995-06-23
CN1090479C (zh) 2002-09-11
DK0675714T3 (da) 1999-09-13
HRP931515A2 (en) 1996-12-31
ATE175872T1 (de) 1999-02-15
LT3300B (en) 1995-06-26
EP0675714B1 (fr) 1999-01-20
CA2152351A1 (fr) 1994-07-07
CA2152351C (fr) 2009-09-22
NZ259790A (en) 1997-02-24
DE69323213D1 (de) 1999-03-04
LV10919A (lv) 1995-12-20
CZ164395A3 (en) 1996-03-13
EE03383B1 (et) 2001-04-16
LTIP1514A (en) 1994-10-25
ZA939552B (en) 1994-10-12
KR100306936B1 (ko) 2001-11-30
DE69323213T2 (de) 1999-07-08
FI952916A0 (fi) 1995-06-14
YU80293A (sh) 1997-12-05

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